Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.56 (caspase-3)
 35,750 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
zinc finger protein 800 9.8
Minichromosome maintenance complex component 3 9.8
BRI3-binding protein 9.8
ubiquitin specific protease 2 9.8
Glyoxylate reductase/hydroxypyruvate reductase 9.8
C1orf201 9.8
zinc finger protein 224 9.8
IRX5 protein 9.8
troponin I, cardiac 9.8
DDX46 protein 9.8
tetratricopeptide repeat domain 9C 9.8
caspase and RIP adapter with death domain 9.8
DAGD 9.8
Death associated protein 3 9.8
LOC401317 9.8
AMPH1 9.8
hect domain and RLD 5 9.8
gamma-glutamyltransferase 2 9.8
Homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein 9.8
interleukin-12 p35 subunit 9.8
CMH1 9.8
ALS2CR7 9.8
ACIN1 protein 9.8
CPP32 9.5
caspase-3 9.4
p21, Cip1 9.2
CMH-1 9.1
DFF35 9.1
caspase-9 8.8
D4S234E 8.8
RAN binding protein 9 8.8
Engulfment and cell motility protein 1 8.8
C4orf22 8.8
Cell death activator 8.8
RING finger protein 121 8.8
sterile alpha motif and leucine zipper containing kinase AZK 8.8
anti-Mullerian hormone receptor type II 8.8
Sal-like 4 (Drosophila) 8.8
Polypeptide N-acetylgalactosaminyltransferase 14 8.8
p21 protein (Cdc42/Rac)-activated kinase 3 8.8
more...
Disease
CMH1 9.8
Bovine tritrichomonosis 8.8
Non-bacterial prostatitis 8.2
DFNA24 8.2
HMN7B 7.8
POF4 7.8
PFM2 7.8
Retinal microaneurysms 7.5
Alcoholic liver damage 7.5
recurrent gallbladder cancer 7.2
Ischemic cerebral infarction 7.0
Brain Ischemia 7.0
nutmeg liver 7.0
Radiocontrast nephropathy 7.0
Malignant insulinoma 6.8
Neonatal necrotizing enterocolitis 6.6
Neonatal pneumonia 6.6
Impaired social interaction 6.6
Fowl cholera 6.6
Coliform mastitis 6.5
endometrial adenoacanthoma 6.5
DECD 6.5
Proteus mirabilis infection 6.5
Eimeriosis 6.5
Diabetic encephalopathy 6.4
DFNA5 6.4
cerebral ischemia/hypoxia 6.3
Reovirus infection 6.3
lung sarcoma 6.1
ADLTE 6.1
Middle cerebral artery occlusion 6.1
Neonatal anoxia 6.0
neck neoplasm 5.9
androgen independent prostate cancer 5.9
Thromboembolic stroke 5.9
Hereditary periodic fever 5.9
IHG 5.8
oral neoplasm 5.8
methionine synthase deficiency 5.8
Glycogen storage disease type Ib 5.8
more...
Symptom
Chronic pelvic pain syndrome 4.9
not coping 4.6
sinus congestion 4.5
Motor dysfunction 4.4
Ear swelling 3.8
Circling 3.8
Inflammatory pain 3.6
Scratch 3.5
skin damage 3.5
Behavioral symptoms 3.4
hyperoxia 3.4
functional recovery 3.2
infant diarrhea 3.0
collapse 3.0
disturbed balance 3.0
stomach pain 2.8
Acute urinary retention 2.8
Joint hypermobility 2.8
memory loss 2.7
Anoxia 2.7
bradykinesia 2.7
startle reaction 2.5
neurological disability 2.5
starvation 2.4
POA 2.3
Tenderness 2.2
impaired motor coordination 2.2
loss of balance 2.0
hypothermia 1.9
incoordination 1.8
male subfertility 1.7
Neuropathic pain 1.7
halitosis 1.6
cachexia 1.6
hyperemesis 1.6
HSA 1.4
forgetfulness 1.4
acute stress 1.3
loss of taste 1.3
dry eye 1.2
more...
Drug
Edratide 9.8
Alisma rhizome 8.8
Lexatumumab 8.8
Condurango 8.8
Teroxirone 8.5
P-Nitrophenol 7.8
Alsterpaullone 7.8
Saccharin sodium 7.8
Montirelin 7.5
Mapatumumab 7.5
Scutellaria root 7.4
Advexin 7.3
Purvalanol 7.3
2-Iminobiotin 7.2
Tandutinib 7.0
Diammonium glycyrrhizinate 7.0
7,8-Dihydroneopterin 6.8
Alexidine 6.8
Bupleurum root 6.6
CED 6.6
Balhimycin 6.6
Angelica dahurica root 6.6
Cassia seed 6.6
3-Methyladenine 6.5
Zedoary 6.5
Lemon oil 6.5
3-Methoxybenzamide 6.5
Proflavin 6.5
Limaprost 6.5
Bv2 6.3
Bear bile 6.3
Epothilone B 6.3
Avasimibe 6.2
Lestaurtinib 6.1
Flurbiprofen axetil 6.1
Berberine chloride 6.0
Sodium phenylbutyrate 6.0
CA-074 6.0
Ulinastatin 6.0
Mevastatin 6.0
more...
Enzyme
caspase-3 9.8
caspase-9 9.1
caspase-7 9.1
caspase-7 9.0
caspase-6 8.8
holocytochrome c synthetase 8.8
caspase-6 8.8
caspase-8 8.7
caspase-2 8.4
caspase-2 8.4
caspase-10 8.2
caspase-10 8.2
PARP 7.8
caspase-4 7.7
caspase-4 7.6
Omi/HtrA2 7.2
D-2-hydroxy acid dehydrogenase 6.8
caspase-5 6.7
caspase-1 6.7
caspase-5 6.6
caspase-11 6.5
caspase-11 6.5
TdT 6.4
mu-calpain 6.3
m-calpain 6.2
MPP 6.0
BCKA 5.7
HPRP 5.6
MT 1 5.6
aspartate dehydrogenase 5.6
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.5
GSK 5.3
neutral sphingomyelinase 5.2
ceramide synthetase 5.2
aspartase 5.1
mitogen-activated protein kinase 5.0
granzyme B 5.0
phosphoinositide 3-kinase 4.9
cdc2 4.9
lactate dehydrogenase 4.8
more...
Compound
C25H28O6 9.8
Iodinin 9.8
C26H30O6 9.8
estra-1,3,5(10)-trien-17-ol 9.8
Podophyllotoxin acetate 9.8
trans-Dihydronarciclasine 9.8
C25H28O6 9.8
crocetin-(beta-d-gentiobiosyl)-(beta-d-glucosyl)-ester 9.8
C25H28O6 9.8
Altersolanol A 9.8
crocetin di-(beta-d-glucosyl)-ester 9.8
C25H28O6 9.8
Dentatin 8.8
Armepavine 8.8
Wighteone 8.8
Uvaretin 8.8
Lunacridine 8.8
4-chloro-N-methylbenzamide 8.8
7-Deacetoxy-7-oxogedunin 8.8
Vitamin K4 8.8
Gymnemic acid I 8.8
Lunacridine 8.8
C25H28O6 8.8
4-chloro-1H-indole 8.8
Abyssinone V 8.8
Methoxycamptothecin 8.8
Decylubiquinone 8.5
Sinularin 8.4
Sinulariolide 8.2
Ginsenoside Rf 8.2
3-Hydroxybiphenyl 8.2
2-Amino-3-hydroxypyridine 8.2
Vitamin K4 8.2
ergosta-7,22-dien-3-ol 8.2
11H-indeno[1,2-b]quinoxaline 8.2
Lycopodine 8.2
Dracorhodin 8.1
Quinalizarin 7.9
Dehydrocostus lactone 7.9
24-Hydroxycholesterol 7.8
more...