Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.56 (
caspase-3
)
35,750
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase-3
35429
Bcl-2
7976
caspase-9
4746
cytochrome c
4160
p53
3259
Mol
3217
caspase-8
3202
PARP
3025
Sep
2325
annexin V
1657
p38
1586
Fas
1553
TNF
1552
tumor necrosis factor
1448
superoxide dismutase
1359
GSH
1239
JNK
1138
poly(ADP-ribose) polymerase
1130
p21
1105
ROS
1073
more...
Disease
cancer
7334
tumor
4651
ischemia
1568
GSH
1240
leukemia
1173
tumor growth
1128
breast cancer
1126
carcinoma
1039
hepatocellular carcinoma
1013
Alzheimer's disease
886
B-cell lymphoma
766
MCF
763
diabetes
740
neuroblastoma
670
lung cancer
653
colon cancer
651
stroke
594
Parkinson's disease
586
prostate cancer
586
cerebral ischemia
552
more...
Symptom
collapse
252
seizures
168
starvation
150
functional recovery
137
anesthesia
113
pain
92
hypothermia
71
hyperoxia
61
diarrhea
61
respiratory distress
40
weakness
27
memory loss
27
thinning
25
ataxia
21
skin damage
19
cachexia
19
tremor
18
bradykinesia
17
exhaustion
15
acute stress
13
more...
Drug
ROS
1073
Monit
151
ascorbate
120
MAP
112
vitamin E
107
Dermatol
104
lysine
103
Cardiovasc
97
IFN-gamma
96
IL-2
92
Ethanol
84
Arsenic trioxide
73
AMC
66
CED
64
CSF
59
p75
56
Taxol
53
Glutathione
51
caffeine
47
TTC
46
more...
Enzyme
caspase-3
35750
caspase-9
4691
mitogen-activated protein kinase
3450
PARP
3345
caspase-8
3091
superoxide dismutase
1778
ERK
1219
catalase
1117
protein kinase
1071
lactate dehydrogenase
937
caspase-1
741
glutathione peroxidase
626
caspase-7
551
caspase-7
532
alanine aminotransferase
433
protein kinase C
430
proteasome
424
focal adhesion kinase
422
luciferase
410
MEK
382
more...
Compound
DNA
6730
oxygen
4966
Dec
2510
MTT
2292
TNF
1552
glucose
1324
GSH
1266
GSH
1266
dUTP
1263
calcium
1090
water
1012
nitric oxide
961
cysteine
950
iodine
898
MDA
859
ATP
825
hydrogen
740
Asp
716
bromide
685
ADP-ribose
662
more...