Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.54 (calpain 3)
 430 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
calpain 3 167
calpain 152
p94 119
CAPN3 87
LGMD2A 60
titin 56
calpastatin 46
Mol 46
dysferlin 42
Sep 36
dystrophin 27
cysteine protease 26
creatine kinase 21
sarcomeric 20
telethonin 16
calpain 2 15
connectin 15
proteasome 14
fukutin-related protein 13
caveolin-3 12
muscle specific 12
ubiquitin 12
LGMD2B 12
muscle protein 11
insulin 9
desmin 9
ADL 9
delta-sarcoglycan 9
MAM 9
TRIM32 9
myosin heavy chain 8
myotilin 8
SOD 8
DAG 8
nebulin 8
SDS 8
CAPN1 8
merosin 7
polypeptide 7
EMD 6
LMNA 6
alpha-actinin 6
GDD 6
atrogin-1 6
alternatively spliced 6
SGC 6
lamin A/C 6
DYSF 6
myostatin 6
crystallin 5
ATP 5
calpain 10 5
cysteine proteinase 5
cathepsin B 5
calpain inhibitor 5
collagen 5
ankyrin 5
SGCA 5
LAMA2 5
ryanodine receptor 5
30K) 5
membrane protein 4
cardiac ankyrin repeat protein 4
RYR1 4
caspase-3 4
Facioscapulohumeral muscular dystrophy 4
glycoprotein 4
caveolin 3 4
MRI 4
DMD 4
dystrophin-associated glycoprotein 4
calmodulin 4
myogenin 4
calcium-activated neutral protease 4
fukutin 4
nCL-2 4
myosin 4
IkappaBalpha 3
apolipoprotein 3
FER 3
growth hormone 3
Gen 3
Titin 3
MuRF1 3
GNE 3
AHNAK 3
gamma-sarcoglycan 3
surface antigen 3
cytokine 3
TTN 3
CARP 3
COL6A1 3
p65 3
MyoD 3
IFN-gamma 3
myoglobin 3
FLNC 3
CaMKII 3
Emery-Dreifuss muscular dystrophy 3
cathepsin 3
GAA 3
cryptic 3
casein 3
NY-ESO-1 2
CAPN11 2
IL-6 2
tyrosine kinase 2
DNAJB6 2
myeloperoxidase 2
muscle LIM protein 2
Fukutin-related protein 2
calcineurin 2
TNF 2
MYOT 2
MHC 2
Connectin 2
Bos taurus 2
mCANP 2
She 2
COL6A3 2
ubiquitin ligase 2
twist 2
CAPN3 protein 2
endoplasmic reticulum 2
lamin A 2
myosin light chain 2
VCP 2
housekeeping 2
Thy-1 2
p28 2
differentially expressed protein 2
UTR 2
p35 2
CAPN10 2
SGCG 2
beta-actin 2
p39 2
MITF 2
FRZB 2
p53 2
p33 2
p12 2
insulin-like growth factor 2
gelsolin 2
beta-catenin 2
fer 2
p84 2
IL-4 2
myopalladin 2
p21 2
HLA 2
extracellular matrix protein 2
POMT1 2
p83 2
SMA 2
muCANP 2
MHC class I 2
X-linked 2
CANP 2
Ubiquitin 2
IFN 2
dominant) 2
Desmin 2
scratch 2
p26 2
fused 2
IL-2 2
cardiac muscle 2
p38 2
calpain 9 2
Dystrophin 2
p51 2
IkappaB alpha 2
IRF 2
alpha, beta 2
cathepsin L 2
SGCB 2
cathepsin D 1
nucleolar protein 1
Calpain-1 1
ANOVA 1
STAT5A 1
CLSTN1 1
CASZ1 1
McLeod syndrome 1
Cathepsin L 1
SERCA2 1
calpain 5 1
S100A10 1
talin 1
SOX10 1
CHI3 1
GSE 1
non-catalytic 1
GMPPB 1
28 kDa 1
lactate dehydrogenase-A 1
TNNT1 1
TRA 1
FERM domain containing 5 1
NGF 1
HLA-B35 1
E3 ubiquitin ligase 1
Na(+)/K(+)-ATPase 1
Telethonin 1
p74 1
peptidase 1
UBIAD1 1
PTRF 1
IL-10 1
HLA class I 1
p45 1
CS protein 1
myoferlin 1
calcium-activated neutral proteinase 1
cardiac troponin T 1
p43 1
cardiac myosin binding protein-C 1
DRw11 1
CPT2 1
NMD 1
myelin-associated glycoprotein 1
Creatine kinase 1
thymus 1
periaxin 1
Axin 1
M-cadherin 1
plectin 1
AHNAK2 1
E-cadherin 1
MAP 1
MART-1 1
transportin 3 1
enolase 1
IL-7 1
C5orf25 1
angiopoietin 1 1
beta-myosin heavy chain 1
CDP 1
PDK4 1
VEGFR2 1
acyl-CoA dehydrogenase 1
4EBP1 1
cytoskeletal protein 1
ankyrin repeat protein 1
NCOR2 1
p16 1
LOX-1 1
GANC 1
FSH 1
superoxide dismutase 1
STAT 1
galectin-3 1
alpha-tubulin 1
Atrogin-1 1
alpha tropomyosin 1
p67 1
sarcospan 1
LPS 1
filensin 1
SARM 1
IGF-I 1
pT1 1
HSP27 1
Ca2+-ATPase 1
insulin-like growth factor I 1
PEST 1
TPA 1
UNC5H2 1
lectin 1
CLP36 1
Stat2 1
p68 1
cyclin A 1
vinculin 1
leptin receptor 1
polymerase I and transcript release factor 1
thyroglobulin 1
DR5 1
chymotrypsin 1
troponin T 1
CDK2 1
acid phosphatase 1
fibronectin 1
78 kDa 1
PANK2 1
NADH 1
Nkx-2.5 1
LGMD2K 1
CKB 1
hemoglobin 1
DR7 1
p49 1
Met 1
myospryn 1
CD9 1
Fukuyama-type congenital muscular dystrophy 1
nSMase2 1
collagenase 1
MLC1 1
NCL 1
p85 1
castor zinc finger 1 1
WAF1 1
CTBP1 1
SAGE 1
FLIP 1
DES 1
bradykinin 1
RyR3 1
transient receptor potential canonical 1 1
TAP 1
TCR 1
glucose-6-phosphate dehydrogenase 1
P10 1
neuronal nitric oxide synthase 1
TRIM29 1
4E-BP1 1
ras 1
calcineurin inhibitor 1
reductase 1
RPL38 1
melusin 1
CLOCK 1
San 1
platelet-derived growth factor 1
nidogen 1
pT3 1
fetuin-A 1
ARMS 1
Trypsin 1
AE4 1
phosphoinositide 3-kinase 1
LOX 1
thrombospondin 2 1
TNF-alpha 1
neuropilin-1 1
SDHA 1
CD18 1
JNK 1
mTOR 1
putative function 1
gamma, delta 1
caveolin 1
interferon 1
LEF1 1
PLEC1 1
dopachrome tautomerase 1
mucin 1
PGC 1
glucosidase 1
CIP1 1
SYNE1 1
ATPase 1
Dickkopf-1 1
IGF1 1
nestin 1
MEK1 1
extracellular signal-regulated kinase 1
nSMase3 1
ferredoxin 1
MYOD 1
p55 1
p32 1
CD52 1
YB-1 1
CAST 1
heat shock protein 1
SMCHD1 1
EF-hand domain 1
KChIP4 1
MLP 1
neuraminidase 1
precursor polypeptide 1
Cx32 1
dimeric 1
troponin C 1
AMPD1 1
Wnt7a 1
insulin receptor 1
proteasome inhibitor 1
CAPN9 1
myosin light chain kinase 1
matrix metalloprotease 1
NFATc3 1
glutamate dehydrogenase 1
HLA-B51 1
FOS 1
Walker 1
M14 1
DMS 1
TCAP 1
80 kDa) 1
p30 1
splicing factor 1 1
vascular endothelial growth factor 1
cyclin-dependent kinase 1
calpain 13 1
translation initiation factor 1
thyroid hormone 1
PML 1
MuRF 1
AARP 1
androgen receptor 1
LAGE-1 1
glucosamine 1
affixin 1
phosphorylase kinase 1
p22 1
phosphoglycerate mutase 1
glial fibrillary acidic protein 1
TRIM 1
p41 1
muscle-specific protein 1
EGR1 1
DR8 1
IL-32 1
IL-5 1
p10 1
melanoma-associated antigen 1
syncytin 1
MATK 1
HLA-DR beta chain 1
retina-specific 1
CD43 1
apolipoprotein D 1
Erb 1
peroxidase 1
PDGF-C 1
CELL 1
AGL 1
ALX1 1
glutathione S-transferase 1
frizzled-related protein 1
lysyl oxidase 1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 1
PTC 1
ubiquitin-conjugating enzyme E2 1
C-terminal peptide 1
VLCAD 1
tumor necrosis factor 1
S100 1
CRYBB2 1
c-Jun 1
UDP-N-acetylglucosamine 2-epimerase 1
carp 1
chitinase 1
PMP22 1
FHL1 1
BP1 1
DLX2 1
GSTM2 1
POMT2 1
ITGB1BP2 1
Hip 1
DARP 1
protein phosphatase 2B 1
erythrocyte membrane protein 1
MDM 1
RACE 1
NCX3 1
alpha-actin 1
RPL4 1
SARM1 1
PTE 1
GAPDH 1
parvalbumin 1
SUMO 1
Glyceraldehyde-3-phosphate dehydrogenase 1
cytochrome c 1
ETFDH 1
neutral sphingomyelinase 1
ALDOB 1
STAT5B 1
cdk2 1
eIF4E 1
p27 1
natural killer cell 1
p60 1
lipoxygenase 1
FLICE 1
Ankyrin 1
adiponectin 1
C-terminal binding protein 1 1
PDLIM3 1
Poly 1
FISH 1
Dictyostelium 1
p54 1
SLN 1
HSP40 1
utrophin 1
ribeye 1
CD74 1
transactivator 1
AP-2 1
olfactory 1
AP1 1
p25 1
transcriptional activator 1
SERCA1 1
RyR1 1
p180 1
GAS7 1
TRPC1 1
MYC 1
NMDA receptor 1
IGF-II 1
PINCH2 1
phosphatidylinositol 3-kinase 1
HLA-DR 1
CAPN8 1
GST 1
interleukin 2 1
p80 1
PAX3 1
STAT5 1
PEF 1
telomeric 1
ubiquitin-like protein 1
p120GAP 1
protein tyrosine kinase 1
SLUG 1
mitogen-activated protein 1
IKK 1
tyrosinase-related protein-1 1
p100 1
beta-tubulin 1
vascular endothelium 1
JKTBP1 1
heavy chain 1
PARVB 1
ZASP 1
AMP 1
dihydropyridine receptor 1
CLCN1 1
Disease
limb-girdle muscular dystrophy 149
muscular dystrophy 74
LGMD2A 53
myopathy 32
muscular atrophy 21
IS1 15
IS2 15
wasting 14
Duchenne muscular dystrophy 12
LGMD2B 12
LGMD2C 9
LGMD2I 9
SDS 8
LGMD2D 8
LGMD2F 7
cancer 7
myositis 7
LGMD2H 6
melanoma 6
cataract 6
LGMD2E 6
tumor 5
neuromuscular disorder 5
sepsis 5
LGMD2G 5
sepsis 5
type 2 diabetes 5
diabetes 5
LGMD2J 4
BMD 4
cardiomyopathy 4
genetic disorder 4
IBM 4
LGMD1A 4
FMD 4
Emery-Dreifuss muscular dystrophy 3
dilated cardiomyopathy 3
AMD 3
LGMD1C 3
SEM 2
LGMD1D 2
hepatocellular carcinoma 2
gastric cancer 2
Alzheimer's disease 2
rare disease 2
LGMD1F 2
LGMD1E 2
metastatic melanoma 2
CMD 2
leukemia 2
spastic paraplegia 2
LGMD1B 2
CMD 2
Mycoplasma 2
epilepsy 2
Lyme disease 2
protein deficiency 2
dermatomyositis 2
mental retardation 1
McLeod syndrome 1
Fukuyama congenital muscular dystrophy 1
Avian infectious bronchitis 1
vitiligo 1
hereditary fructose intolerance 1
Ullrich 1
stroke 1
MDC1A 1
hypertrophic cardiomyopathy 1
MDM 1
DM1 1
tetanus 1
tumor growth 1
tyrosinemia 1
DMS 1
polymyositis 1
PML 1
lipoatrophy 1
ischemia 1
Maedi 1
EMD 1
mental retardation 1
diabetic cataract 1
minimal residual disease 1
lentigo 1
motor neuron disease 1
confusion 1
malnutrition 1
brain atrophy 1
lipodystrophy 1
vaccinia 1
MDI 1
carcinogenesis 1
aggressiveness 1
blue nevus 1
brain tumor 1
keratoconjunctivitis 1
West 1
mole 1
atherosclerosis 1
hepatitis B 1
familial hemophagocytic lymphohistiocytosis 1
mole 1
Infection 1
Disuse atrophy 1
Infections 1
celiac disease 1
LGMD2K 1
ischemic cardiomyopathy 1
plaque 1
galactosemia 1
dysplastic nevi 1
mitochondrial myopathy 1
heart failure 1
camptocormia 1
fits 1
obesity 1
chronic disease 1
Leukemia 1
amyotrophic lateral sclerosis 1
hypertension 1
toxic shock syndrome 1
right bundle branch block 1
transitional cell carcinoma 1
papillary thyroid cancer 1
sarcoma 1
tumor progression 1
Evans 1
cornea 1
foot drop 1
metastases 1
liver cancer 1
parkinsonism 1
Diaphragm 1
benign nevi 1
atrioventricular block 1
choroid plexus papilloma 1
LGMD1G 1
DES 1
Symptom
weakness 46
starvation 3
myalgia 3
dyspnea 2
cachexia 2
fatigue 1
chills 1
Tenderness 1
pain 1
anesthesia 1
anorexia 1
abnormal gait 1
syncopal episodes 1
Drug
IFN-gamma 3
IL-2 2
lysine 2
caffeine 2
MAP 1
CaCl2 1
Cardiovasc 1
MDM 1
CaCl2 1
NADH 1
ENT 1
PTC 1
DMI 1
AMC 1
CaCl2 1
CDP 1
Enzyme
calpain 3 430
calpain 3 154
m-calpain 34
mu-calpain 31
creatine kinase 21
proteasome 14
calpain 10 5
cathepsin B 5
focal adhesion kinase 4
protein kinase 4
caspase-3 3
trypsin 3
reverse transcriptase 3
CaMKII 3
peroxidase 3
papain 2
beta-galactosidase 2
mitogen-activated protein kinase 2
cathepsin L 2
glutathione S-transferase 2
calcineurin 2
neuraminidase 1
acyl-CoA dehydrogenase 1
acid phosphatase 1
chymotrypsin 1
actinidin 1
superoxide dismutase 1
myosin light chain kinase 1
glutamate dehydrogenase 1
cathepsin D 1
phosphoinositide 3-kinase 1
phospholipase C 1
PDK1 1
collagenase 1
p100 1
phosphorylase kinase 1
glucose-6-phosphate dehydrogenase 1
enolase 1
phosphatidylinositol 3-kinase 1
calpain 5 1
cdc2 1
UDP-N-acetylglucosamine 2-epimerase 1
luciferase 1
acyl-CoA dehydrogenase 1
calpain 9 1
lipoxygenase 1
p80 1
neutral sphingomyelinase 1
transcriptase 1
glyceraldehyde-3-phosphate dehydrogenase 1
deaminase 1
MAP 1
chitinase 1
MEK 1
IKK 1
cathepsin G 1
firefly luciferase 1
PGM 1
glutamate dehydrogenase 1
glutamate dehydrogenase 1
lysyl oxidase 1
DCF 1
ATPase 1
RNA polymerase 1
Compound
calcium 88
Dec 39
DNA 24
Clin 21
cysteine 21
tyrosine 8
SDS 8
serine 6
ATP 5
COS 5
His 4
leucine 4
DMD 4
alanine 3
MAK 3
E-64 3
glucose 3
methionine 3
DEAE 2
Phe 2
TNF 2
NH2 2
lysine 2
sulfate 2
Estrogen 2
sodium 2
Emery 2
nitric oxide 2
Ubiquitin 2
oxygen 2
caffeine 2
Asp 2
salt 2
nitrogen 2
Estrogen 1
urea 1
aspartic acid 1
hydrogen 1
retinoic acid 1
CaCl2 1
zinc 1
MSM 1
DMI 1
Pima 1
aspartic acid 1
arginine 1
NADH 1
TCAP 1
Tyrosine 1
Polypeptide 1
EDTA 1
Cyclosporine 1
DMS 1
L-leucine 1
nickel 1
threonine 1
Optimal 1
Creatine 1
Cardiol 1
CDP 1
DMI 1
TPA 1
TAP 1
HgCl2 1
aspartic acid 1
NTA 1
MAP 1
Mendel 1
Heparin 1
Insulin 1
acetate 1
Trypsin 1
creatinine 1
aspartic acid 1
AMP 1
glutamic acid 1
DES 1
Carnosine 1
water 1
EDTA 1
3-methylhistidine 1
TPA 1