Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.54 (
calpain 3
)
430
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
calpain 3
167
calpain
152
p94
119
CAPN3
87
LGMD2A
60
titin
56
calpastatin
46
Mol
46
dysferlin
42
Sep
36
dystrophin
27
cysteine protease
26
creatine kinase
21
sarcomeric
20
telethonin
16
calpain 2
15
connectin
15
proteasome
14
fukutin-related protein
13
caveolin-3
12
more...
Disease
limb-girdle muscular dystrophy
149
muscular dystrophy
74
LGMD2A
53
myopathy
32
muscular atrophy
21
IS2
15
IS1
15
wasting
14
Duchenne muscular dystrophy
12
LGMD2B
12
LGMD2C
9
LGMD2I
9
SDS
8
LGMD2D
8
LGMD2F
7
cancer
7
myositis
7
melanoma
6
cataract
6
LGMD2E
6
more...
Symptom
weakness
46
starvation
3
myalgia
3
dyspnea
2
cachexia
2
fatigue
1
chills
1
Tenderness
1
pain
1
anesthesia
1
anorexia
1
abnormal gait
1
syncopal episodes
1
Drug
IFN-gamma
3
IL-2
2
lysine
2
caffeine
2
MAP
1
CaCl2
1
Cardiovasc
1
MDM
1
CaCl2
1
NADH
1
ENT
1
PTC
1
DMI
1
AMC
1
CaCl2
1
CDP
1
Enzyme
calpain 3
430
calpain 3
154
m-calpain
34
mu-calpain
31
creatine kinase
21
proteasome
14
calpain 10
5
cathepsin B
5
focal adhesion kinase
4
protein kinase
4
reverse transcriptase
3
CaMKII
3
peroxidase
3
trypsin
3
caspase-3
3
beta-galactosidase
2
mitogen-activated protein kinase
2
papain
2
glutathione S-transferase
2
calcineurin
2
more...
Compound
calcium
88
Dec
39
DNA
24
Clin
21
cysteine
21
tyrosine
8
SDS
8
serine
6
COS
5
ATP
5
DMD
4
His
4
leucine
4
methionine
3
E-64
3
glucose
3
MAK
3
alanine
3
NH2
2
Asp
2
more...