Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.36 (
caspase-1
)
6,285
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ICE
0.167
NLRP3
0.082
IL-18
0.041
ASC
0.032
pyrin
0.029
Caspase-1
0.021
AIM2
0.019
NLRC4
0.018
gasdermin D
0.010
apoptosis-associated speck-like protein containing a CARD
0.009
NLRP1
0.007
CPP32
0.006
GSDMD
0.004
NALP3
0.003
NOD
0.003
gasdermin
0.003
interleukin-18
0.003
NLRP3 protein
0.003
NLRP6
0.002
NALP1
0.002
IPAF
0.002
caspase-3
0.002
IL-1
0.001
p20
0.001
CED
0.001
ICEBERG
0.001
caspase-8
0.001
CASP1
0.001
TXNIP
0.001
P2X7
0.001
cytokine
0.001
CMK
0.001
NEK7
0.001
THP
0.001
AII
0.001
cysteine protease
0.001
p10
0.001
LPS
0.001
pyrin domain containing 1
0.001
Fas
0.001
more...
Disease
NOD
0.003
Muckle-Wells syndrome
0.000
CMH1
0.000
Oral pemphigus vulgaris
0.000
gout
0.000
Chronic skin disease
0.000
Non-bacterial prostatitis
0.000
cowpox
0.000
familial Mediterranean fever
0.000
POF4
0.000
Alcoholic liver damage
0.000
Mevalonate kinase deficiency
0.000
anthrax
0.000
bacterial infection
0.000
colitis
0.000
Legionella
0.000
sepsis
0.000
Gouty arthritis
0.000
sepsis
0.000
ICE syndrome
0.000
Acute glaucoma
0.000
NOMID
0.000
Dissecting aortic aneurysm
0.000
Vaccinia virus infection
0.000
Pulmonary fat embolism
0.000
atherosclerosis
0.000
peritonitis
0.000
bacillary dysentery
0.000
MYP3
0.000
Sepsis-associated encephalopathy
0.000
Shigella
0.000
Macular corneal dystrophy
0.000
ischemia
0.000
Shigella flexneri
0.000
Yersinia
0.000
diabetic cardiomyopathy
0.000
virus infection
0.000
cerebral ischemia
0.000
salmonellosis
0.000
infectious diseases
0.000
more...
Symptom
Chronic pelvic pain syndrome
0.000
localized erythema
0.000
General symptoms
0.000
collapse
0.000
peri-menopausal
0.000
hyperoxia
0.000
dry eye
0.000
male subfertility
0.000
starvation
0.000
pain
0.000
respiratory distress
0.000
hypothermia
0.000
diarrhea
0.000
chills
0.000
despair
0.000
arthralgia
0.000
splenomegaly
0.000
memory loss
0.000
dry skin
0.000
emaciation
0.000
functional recovery
0.000
exhaustion
0.000
abnormal gait
0.000
seizures
0.000
fatigue
0.000
headache
0.000
nausea
0.000
acute stress
0.000
erythema
0.000
chorea
0.000
overweight
0.000
tense
0.000
anorexia
0.000
acidity
0.000
cachexia
0.000
vomiting
0.000
asthenia
0.000
flushing
0.000
myalgia
0.000
polyuria
0.000
more...
Drug
CED
0.002
Mifobate
0.000
ROS
0.000
Talabostat
0.000
CA-074
0.000
Bv2
0.000
Lexatumumab
0.000
Anakinra
0.000
IL-1ra
0.000
Platonin
0.000
Rilonacept
0.000
AMC
0.000
Atractylodes rhizome
0.000
Roferon A
0.000
Ferric ammonium citrate
0.000
IFN-gamma
0.000
Hirudoid
0.000
Adenosine Monophosphate
0.000
Irofulven
0.000
Peanut oil
0.000
Interferon alfa-2a
0.000
Amlexanox
0.000
Tenidap
0.000
Butaprost
0.000
IFN-beta
0.000
Tipifarnib
0.000
3-Methyladenine
0.000
Gold sodium thiomalate
0.000
G-CSF
0.000
Lipitor
0.000
Auranofin
0.000
Batimastat
0.000
Batimastat
0.000
Immune globulin
0.000
Glybenclamide
0.000
Pirfenidone
0.000
Paliperidone
0.000
Lipitor
0.000
Lipitor
0.000
Clodronate
0.000
more...
Enzyme
caspase-1
1.000
caspase-11
0.017
caspase-11
0.017
caspase-4
0.005
caspase-5
0.005
caspase-4
0.005
caspase-5
0.005
proteinase A
0.004
caspase-3
0.002
Pla
0.001
caspase-8
0.001
caspase-2
0.001
caspase-6
0.001
caspase-2
0.001
caspase-6
0.001
caspase-7
0.001
caspase-7
0.000
cathepsin B
0.000
caspase-10
0.000
caspase-10
0.000
PARP
0.000
caspase-9
0.000
mitogen-activated protein kinase
0.000
meprin B
0.000
thermomycolase
0.000
granzyme B
0.000
adenain
0.000
NADPH oxidase
0.000
NADPH oxidase
0.000
lactate dehydrogenase
0.000
D-cysteine desulfhydrase
0.000
NS protease
0.000
mevalonate kinase
0.000
apyrase
0.000
streptomycin adenylyltransferase
0.000
aspartase
0.000
streptopain
0.000
alpha-lytic protease
0.000
TSP-1
0.000
cathepsin V
0.000
more...
Compound
ASC
0.032
THP
0.001
THP
0.001
CMK
0.001
TNF
0.000
Asp
0.000
ATP
0.000
Chelidonic acid
0.000
leucine
0.000
DCB
0.000
Ginsenoside Rf
0.000
DCB
0.000
oxygen
0.000
DCB
0.000
cysteine
0.000
2-methyl-6-undecylpiperidine
0.000
DCB
0.000
Theasinensin A
0.000
DCB
0.000
Nodakenin
0.000
5-Methoxytryptophan
0.000
Nigericin
0.000
DNA
0.000
Cucurbitacin D
0.000
dUTP
0.000
3,4-pyridinedicarboxylic acid
0.000
2-hydroxy-1-propanesulfonic acid
0.000
TPCK
0.000
Wedelolactone
0.000
1-heptadecene
0.000
Dracorhodin
0.000
N-acetylcysteine
0.000
Rhaponticin
0.000
alanine
0.000
Ruscogenin
0.000
Dihydromyricetin
0.000
potassium
0.000
Gedunin
0.000
Glibenclamide
0.000
Aluminum hydroxide
0.000
more...