Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.36 (caspase-1)
 6,285 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Ly6/PLAUR domain-containing protein 6 12.3
ILPIP 12.3
DAGD 12.3
ICE 12.3
caspase and RIP adapter with death domain 12.3
CMH1 12.3
leucine-rich repeat-containing 3 12.3
toll-like receptor adaptor molecule 2 12.3
ICEBERG 11.8
PYPAF2 11.6
CARD12 11.6
IPAF 11.4
pyrin domain containing 1 11.4
apoptosis-associated speck-like protein containing a CARD 11.4
transmembrane protein 176B 11.3
Tripartite motif-containing protein 31 11.3
guanylate binding protein 4 11.3
Ras-related protein Rab-37 11.3
IGLL3 11.3
GIG4 11.3
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor 11.3
USP50 11.3
NLRP13 11.3
NLRC4 11.3
gasdermin D 11.2
GSDMD 11.2
NALP1 11.1
NLRP3 protein 11.1
AIM2 11.1
NLRP6 11.0
NLRP1 10.9
NIMA-related kinase 7 10.9
PYPAF7 10.9
NALP2 10.9
ICH-2 10.8
HIPPI 10.8
AIM2 protein 10.8
NLRP3 10.8
NEK7 10.8
cPOP2 10.7
more...
Disease
CMH1 12.3
Oral pemphigus vulgaris 11.3
Non-bacterial prostatitis 10.7
Chronic skin disease 10.7
POF4 10.3
Alcoholic liver damage 10.0
Acute glaucoma 8.6
ICE syndrome 8.6
Muckle-Wells syndrome 8.5
Mevalonate kinase deficiency 8.4
NOMID 8.3
Vaccinia virus infection 8.2
Dissecting aortic aneurysm 8.2
Pulmonary fat embolism 8.2
NOD 8.1
Gouty arthritis 7.9
MYP3 7.9
Macular corneal dystrophy 7.8
Therapy-related myelodysplastic syndrome 7.5
Sepsis-associated encephalopathy 7.4
DFNA5 7.4
CINCA syndrome 7.3
malignant myeloma 7.2
gouty nephropathy 7.2
cowpox 7.2
Geographic atrophy 7.1
CPS deficiency 7.1
WTS 6.9
Aortic atherosclerosis 6.9
Parvovirus infection 6.9
Pulmonary eosinophilia 6.8
rhabdoid tumor of the kidney 6.8
Leishmania braziliensis infection 6.8
Viral myocarditis 6.7
familial Mediterranean fever 6.6
Diabetic encephalopathy 6.6
bacterial dysentery 6.6
bacillary dysentery 6.6
Hereditary tyrosinemia type I 6.5
Neonatal infection 6.3
more...
Symptom
Chronic pelvic pain syndrome 7.4
localized erythema 7.4
General symptoms 6.4
peri-menopausal 4.8
male subfertility 4.3
dry eye 3.5
hyperoxia 3.1
despair 2.7
dry skin 2.3
emaciation 2.3
chills 2.2
abnormal gait 2.2
collapse 2.1
memory loss 2.1
arthralgia 1.8
splenomegaly 1.6
hypothermia 1.5
starvation 1.5
respiratory distress 1.5
chorea 1.3
tense 1.2
functional recovery 1.2
exhaustion 1.2
acute stress 1.1
asthenia 0.9
cachexia 0.8
polyuria 0.7
flushing 0.7
diarrhea 0.7
myalgia 0.6
erythema 0.6
anorexia 0.6
cerebellar ataxia 0.5
acidity 0.4
nausea 0.4
acute pain 0.4
pelvic pain 0.3
apathy 0.3
overweight 0.2
distraction 0.1
more...
Drug
Mifobate 12.3
Talabostat 10.5
Bv2 9.8
Lexatumumab 9.7
CED 9.5
CA-074 8.5
Platonin 8.4
Rilonacept 8.3
Atractylodes rhizome 8.1
Roferon A 7.9
Ferric ammonium citrate 7.9
Hirudoid 7.5
Adenosine Monophosphate 7.4
Irofulven 7.4
Anakinra 7.3
Peanut oil 7.2
Interferon alfa-2a 6.9
Amlexanox 6.8
Tenidap 6.5
Butaprost 6.4
Tipifarnib 6.2
IL-1ra 6.1
AMC 6.0
Gold sodium thiomalate 6.0
Lipitor 5.9
3-Methyladenine 5.9
Batimastat 5.8
Batimastat 5.8
Immune globulin 5.7
Glybenclamide 5.7
Paliperidone 5.6
Lipitor 5.5
Lipitor 5.5
Auranofin 5.5
Red ginseng 5.4
Pirfenidone 5.4
Idebenone 5.4
Pepstatin 5.4
Clodronate 5.3
Zevalin 5.3
more...
Enzyme
caspase-1 12.3
caspase-5 11.7
caspase-11 11.5
caspase-5 11.5
caspase-11 11.4
proteinase A 10.6
caspase-4 10.6
caspase-4 10.4
thermomycolase 9.5
meprin B 9.4
Pla 9.0
caspase-6 9.0
adenain 8.7
caspase-6 8.7
caspase-2 8.6
caspase-2 8.6
caspase-10 8.5
caspase-10 8.5
NS protease 8.3
D-cysteine desulfhydrase 8.3
caspase-7 8.2
caspase-7 8.0
streptomycin adenylyltransferase 8.0
streptopain 7.7
caspase-8 7.5
granzyme M 7.4
cathepsin V 7.3
alpha-lytic protease 7.1
cathepsin B 6.9
aspartase 6.9
granzyme K 6.9
cholesterol 25-hydroxylase 6.8
mevalonate kinase 6.7
caspase-3 6.7
deoxyhypusine hydroxylase 6.3
serralysin 6.2
legumain 6.0
TSP-1 5.9
apyrase 5.7
caspase-9 5.7
more...
Compound
Ginsenoside Rf 10.7
ASC 10.5
Chelidonic acid 10.3
2-methyl-6-undecylpiperidine 10.3
Theasinensin A 10.0
5-Methoxytryptophan 9.7
Nodakenin 9.7
Cucurbitacin D 9.1
CMK 8.9
3,4-pyridinedicarboxylic acid 8.8
2-hydroxy-1-propanesulfonic acid 8.8
1-heptadecene 8.4
Dracorhodin 8.3
Wedelolactone 8.3
Rhaponticin 8.2
Ruscogenin 8.1
Nigericin 7.9
Gedunin 7.8
Micheliolide 7.8
Menthone 7.8
Micheliolide 7.8
DCB 7.6
DCB 7.6
4-phenyl-2-butanone 7.5
LLY 7.5
Sodium hydrosulfide 7.5
Propantheline 7.4
Eudesmol 7.4
DCB 7.4
Androstenediol 7.4
Diisononyl phthalate 7.4
Mauve 7.4
N-acetyltryptophan 7.4
Gentiopicroside 7.4
4-phenyl-2-butanone 7.4
Acacetin 7.3
Aluminum hydroxide 7.3
Dihydromyricetin 7.3
Physcion 7.3
Merbarone 7.3
more...