Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.36 (caspase-1)
 6,285 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CMH1 12.3
ICE 12.3
toll-like receptor adaptor molecule 2 12.3
leucine-rich repeat-containing 3 12.3
DAGD 12.3
ILPIP 12.3
Ly6/PLAUR domain-containing protein 6 12.3
caspase and RIP adapter with death domain 12.3
ICEBERG 11.8
CARD12 11.6
PYPAF2 11.6
IPAF 11.4
pyrin domain containing 1 11.4
apoptosis-associated speck-like protein containing a CARD 11.4
transmembrane protein 176B 11.3
Ras-related protein Rab-37 11.3
guanylate binding protein 4 11.3
IGLL3 11.3
USP50 11.3
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor 11.3
GIG4 11.3
Tripartite motif-containing protein 31 11.3
NLRP13 11.3
NLRC4 11.3
gasdermin D 11.2
GSDMD 11.2
NALP1 11.1
NLRP3 protein 11.1
AIM2 11.1
NLRP6 11.0
NLRP1 10.9
NIMA-related kinase 7 10.9
PYPAF7 10.9
NALP2 10.9
ICH-2 10.8
HIPPI 10.8
AIM2 protein 10.8
NLRP3 10.8
NEK7 10.8
protease E) 10.7
cPOP2 10.7
NLRP11 10.7
CAGE1 10.7
DDX19A 10.7
RAB39A 10.7
NLRP1 protein 10.7
gasdermin 10.7
pyrin 10.7
Caspase-1 10.6
ASC 10.5
PYPAF3 10.5
Chemokine (C-C motif) ligand 3 10.3
NLR family, pyrin domain containing 3 10.3
NLRP10 10.2
CMH-1 10.1
CPP32 10.1
IL-18 10.0
IL-1F7 10.0
TNFRSF1A-associated via death domain 10.0
EIF-5A 10.0
POP3 10.0
NALP3 10.0
CARD8 9.9
leucine-rich-repeat protein 9.9
CASP1 9.9
CASP-1 9.9
NLRP8 9.7
potassium inwardly-rectifying channel 9.7
Lysophosphatidic acid receptor 1 9.7
TNF receptor-associated factor 4 9.7
ASC2 9.7
ICERE-1 9.7
NLRP12 9.7
TXNIP 9.7
ASC-1 9.6
ICH-1L 9.6
APIP 9.6
ICH3 9.6
IL-1F6 9.6
CIAS1 9.5
TMS1 9.5
NLRP9 9.5
EEA1 protein 9.5
huntingtin interacting protein 1 9.5
interleukin-18 9.5
p20 9.4
RFC140 9.4
PSTPIP2 9.4
BRCC3 9.4
GBP5 9.3
COMMD10 9.3
Septin-2 9.3
neural cell adhesion molecule 2 9.3
P2X purinoceptor 7 9.3
NAIP 9.3
NLRP7 9.2
CARD-containing protein 9.2
Fas-associating protein 9.1
PN-I 9.1
cell death inhibiting RNA 9.1
myotubularin-related protein 3 9.1
Adapter protein 9.1
CMK 9.1
POP1 9.1
caspase 4 9.1
NLRP4 9.1
DEFA3 9.1
CED 9.0
NLRP2 9.0
GBP3 9.0
DFF35 9.0
RAIDD 9.0
toll-like receptor 6 9.0
glutathione S-transferase omega 1-1 9.0
NLRC3 9.0
RIP2 8.9
IL18 8.9
DHX33 8.8
SIGLEC5 8.8
IL-1F9 8.8
Pannexin-1 8.8
interleukin 18 8.7
ORCTL3 8.7
CARD6 8.7
caspase-14 8.6
Caspase-activated DNase 8.6
Friend leukemia virus integration 1 8.6
calmodulin 3 8.6
SFRS3 8.6
EIF3A 8.6
caspase 2 8.6
IL-18Rbeta 8.5
TUBB6 8.5
endosomal adaptor protein 8.5
MIHC 8.5
Interleukin-18 8.4
formin 2 8.4
CCL4L 8.4
ETS1 protein 8.4
ABRO1 8.4
p10 8.4
IFI16 8.4
ASCI 8.3
serine/threonine kinase 2 8.3
CLAN 8.3
SIPP1 8.3
DPP9 8.2
IL-1Rrp2 8.2
GBP2 8.2
MAP kinase kinase 3 8.2
P2X7 8.2
INCA 8.2
AG11 8.1
CASP-9 8.1
POP2 8.1
TMS-1 8.1
Interleukin 18 8.1
Nod1 8.1
NOD 8.1
leucine-rich repeat protein 8.1
SR-A1 8.1
TSLP protein 8.1
IFIX 8.1
neuronal apoptosis inhibitory protein 8.0
Siglec-14 8.0
IL-1F8 8.0
TXNDC5 8.0
Meprin A 8.0
GABRE 8.0
DPR1 8.0
MATP 8.0
AII 8.0
Y8) 7.9
IL18R1 7.9
DPP8 7.9
RPS6KA1 7.9
HORMAD2 7.9
LAP3 7.9
casp 7.9
Bcl-10 7.9
CASP4 7.9
ATP11C 7.9
nucleotide-binding oligomerization domain 2 7.9
interleukin-18 binding protein 7.8
PKN1 7.8
GSDMC 7.8
UBE2O 7.8
pejvakin 7.8
TOSO 7.8
CD95 antigen 7.8
guanine nucleotide exchange factor for Rap1 7.8
DEFA1 7.8
UBR2 7.8
NDUFS7 7.8
FLICE 7.8
RIP3 7.7
CXADR 7.7
CIB2 7.7
ATP receptor 7.7
caspase 6 7.7
IL-18BP 7.7
caspase 7 7.7
PITSLRE 7.7
SLC15A4 7.7
FMN2 7.7
MTMR3 7.7
CHST6 7.7
prostaglandin F receptor 7.7
PRAP 7.7
Trif 7.6
NLRC5 7.6
organic anion transporter 4 7.6
STP2 7.6
Death-associated protein kinase 1 7.6
ACZ 7.6
G protein-coupled receptor 120 7.6
PSTPIP1 7.6
p53-inducible protein 7.6
RIPK2 7.6
IL-1F10 7.6
thymic stromal lymphopoietin 7.5
P2RX7 7.5
PRB1 7.5
carboxypeptidase B1 7.5
Thioredoxin-interacting protein 7.5
MEFV 7.5
RIPK3 7.5
DUSP7 7.4
SENP7 7.4
PRKCD 7.4
DLM-1 7.4
proteinase inhibitor 9 7.4
PSTPIP 7.4
thioredoxin interacting protein 7.4
15-PGDH 7.4
TNFRSF8 7.4
p12 subunit 7.4
DFNA5 7.4
TSLPR 7.3
cysteine protease 7.3
MLKL 7.3
UNC93B1 7.3
NLRX1 7.3
MNDA 7.3
BCAP 7.3
CRADD 7.3
ALG9 7.2
nucleotide-binding oligomerization domain containing 2 7.2
AQP2 protein 7.2
TNFRSF21 7.2
DEFB4 7.2
cathepsin V 7.2
p10 protein 7.2
PM/Scl-75 7.2
SLY 7.2
PEP3 7.2
IL-33 7.2
IL-32 7.1
caspase-8 7.1
MLT1 7.1
APCL 7.1
HOIL-1 7.1
NLRP5 7.1
PTR3 7.1
TRIM16 7.1
THP1 7.1
NOD1 7.1
IL-22BP 7.1
RILP 7.1
STF-1 7.1
IL1B 7.1
APO-1 7.1
Rab-interacting lysosomal protein 7.1
ICAD 7.1
CASP11 7.0
myeloid differentiation primary response gene 88 7.0
cathepsin L2 7.0
STE20-like kinase 7.0
ADAM10 protein 7.0
RIG-1 7.0
RPL19 7.0
BAG6 7.0
LPIN2 7.0
MKP-5 7.0
phosphate cyclase 7.0
CASP5 7.0
PKG1 7.0
Claudin 1 7.0
ECTO 7.0
B3.1 6.9
ASK2 6.9
POH1 6.9
ASIC4 6.9
ESET 6.9
TRIM8 6.9
SARM 6.9
cathepsin B 6.9
THP 6.9
CARD9 6.9
CRIg 6.9
SENP6 6.9
HMGB1 6.9
PIDD 6.9
Ameloblastin 6.9
BSX 6.9
FADD 6.9
interferon regulatory factor-1 6.9
GDI 6.9
PACRG 6.8
p202 6.8
IL18RAP 6.8
GAS2 6.8
TRADD 6.8
adaptor protein 6.8
High-mobility group box 1 6.8
BCL6 protein 6.8
Heat shock transcription factor 1 6.8
signal transducer and activator of transcription-1 6.8
RAR-related orphan receptor gamma 6.8
Interferon regulatory factor 1 6.8
more...
Disease
CMH1 12.3
Oral pemphigus vulgaris 11.3
Non-bacterial prostatitis 10.7
Chronic skin disease 10.7
POF4 10.3
Alcoholic liver damage 10.0
Acute glaucoma 8.6
ICE syndrome 8.6
Muckle-Wells syndrome 8.5
Mevalonate kinase deficiency 8.4
NOMID 8.3
Pulmonary fat embolism 8.2
Vaccinia virus infection 8.2
Dissecting aortic aneurysm 8.2
NOD 8.1
Gouty arthritis 7.9
MYP3 7.9
Macular corneal dystrophy 7.8
Therapy-related myelodysplastic syndrome 7.5
Sepsis-associated encephalopathy 7.4
DFNA5 7.4
CINCA syndrome 7.3
malignant myeloma 7.2
gouty nephropathy 7.2
cowpox 7.2
Geographic atrophy 7.1
CPS deficiency 7.1
WTS 6.9
Parvovirus infection 6.9
Aortic atherosclerosis 6.9
Pulmonary eosinophilia 6.8
rhabdoid tumor of the kidney 6.8
Leishmania braziliensis infection 6.8
Viral myocarditis 6.7
familial Mediterranean fever 6.6
Diabetic encephalopathy 6.6
bacterial dysentery 6.6
bacillary dysentery 6.6
Hereditary tyrosinemia type I 6.5
Neonatal infection 6.3
West Nile encephalitis 6.1
placental disorders 6.1
Histoplasma capsulatum infection 6.1
Crescentic glomerulonephritis 6.1
FCU 6.1
Influenza A virus infection 6.1
Apical periodontitis 6.1
trichophytosis 6.0
gout 6.0
Intestinal ischemia 6.0
Critically Ill 6.0
Streptococcus pneumoniae meningitis 6.0
favus 5.9
Klebsiella pneumoniae infection 5.9
Aspergillus fumigatus infection 5.9
Lumbar disc herniation 5.9
Submandibular gland 5.8
Parasitic infection 5.8
vascular ischemia 5.8
anthrax 5.7
Prostate tumor 5.7
Irritant contact dermatitis 5.7
PAPA 5.6
Middle cerebral artery occlusion 5.6
cough variant asthma 5.6
Candida sepsis 5.6
maple syrup urine disease 5.6
monocytic leukemia 5.6
endotoxic shock 5.5
diabetic cardiomyopathy 5.5
Burkitt-like lymphoma 5.5
Pulmonary infiltrates 5.5
Chronic inflammatory demyelinating polyradiculoneuropathy 5.5
Prosthetic valve endocarditis 5.5
AML progression 5.4
dental abscess 5.4
Oral infection 5.4
closed angle glaucoma 5.3
Diarrheal disease 5.3
DSS 5.3
Fungal keratitis 5.3
Schnitzler syndrome 5.2
Legionella 5.2
Asherman's syndrome 5.2
Shigella flexneri 5.1
Recessive dystrophic epidermolysis bullosa 5.1
mouse leukemia L1210 5.1
PFD 5.1
RP3 5.1
testicular dysfunction 5.1
Ureteral obstruction 5.1
Visna 5.0
pseudotuberculosis 5.0
DSS 5.0
Diabetes and Pregnancy 5.0
FAB M4 5.0
aggressive lymphoma 5.0
salivary gland cancer 5.0
Aeromonas hydrophila infection 5.0
VES 4.9
Dengue hemorrhagic fever 4.9
legionellosis 4.9
Diabetic peripheral neuropathy 4.9
PCD 4.9
VISA 4.9
Maedi 4.8
genital infection 4.8
bullous dermatoses 4.8
tularemia 4.8
Sendai virus infection 4.7
bacterial infection 4.7
pseudogout 4.7
salmonellosis 4.7
Gram-negative bacteremia 4.7
Plasmodium vivax infection 4.7
Shigella 4.7
Renal fibrosis 4.6
Small intestine 4.6
pulpitis 4.6
X-linked lymphoproliferative syndrome 4.6
geographic tongue 4.5
cardiac overload 4.5
AA amyloidosis 4.5
acute monocytic leukemia 4.5
immunopathology 4.5
infectious colitis 4.5
Allergic asthma 4.5
Invasive pulmonary aspergillosis 4.5
colitis 4.5
T-cell deficiency 4.5
Alcoholic liver disease 4.5
normocytic anemia 4.4
Pseudomonas infection 4.4
GM2 gangliosidosis 4.4
Hidradenitis suppurativa 4.4
Franklin 4.4
chronic cystitis 4.4
Cerebral venous thrombosis 4.3
renal ischemia 4.3
OPS 4.3
vibriosis 4.3
Yersinia 4.3
alcoholic fatty liver 4.3
pregnancy disorder 4.3
Werdnig-Hoffmann disease 4.3
low-grade lymphomas 4.2
LAD2 4.2
Classical swine fever 4.2
Choriocarcinoma 4.2
PIE 4.2
enterocolitis 4.2
Age-related macular degeneration 4.2
SOST 4.2
PME 4.2
Mixed infection 4.2
polyradiculoneuropathy 4.2
Autoimmune hepatitis 4.2
Blocking 4.2
peritonitis 4.2
CMD 4.1
hyperuricemia 4.1
beriberi 4.1
melioidosis 4.1
histiocytoma 4.1
scarlet fever 4.1
AOS 4.1
rhinovirus infection 4.1
CMD 4.1
Silence 4.1
acute pharyngitis 4.1
Helicobacter pylori gastritis 4.1
Chlamydia trachomatis infection 4.1
intestinal cancer 4.1
beryllium disease 4.1
secondary AML 4.0
Endothelial dysfunction 4.0
hypertensive nephropathy 4.0
atypical pneumonia 4.0
CYLD 4.0
Diffuse large B-cell lymphoma 3.9
Candida albicans infection 3.9
XPB 3.9
PTP 3.9
Febrile neutropenia 3.9
OCP 3.9
OPA1 3.9
LYP 3.9
Angiostrongylus cantonensis 3.9
SDA 3.9
cerebral ischemia 3.9
RSV infection 3.9
Brucella abortus 3.9
Cerebral malaria 3.9
polyneuritis 3.8
Severe sepsis 3.8
CVS 3.8
LQT1 3.8
epididymo-orchitis 3.8
protozoan infection 3.8
hyperhomocysteinemia 3.8
HIV-2 infection 3.8
immune complex disease 3.8
silicosis 3.8
PCS 3.8
Liver regeneration 3.8
Staphylococcus aureus infection 3.8
FAS 3.8
Bielschowsky 3.8
AS1 3.8
stage III NSCLC 3.8
DBM 3.8
brain edema 3.7
Shigella sonnei 3.7
IPS 3.7
dyschondroplasia 3.7
bubonic plague 3.7
sepsis 3.7
diabetic retinopathy 3.7
Pulmonary infection 3.7
RTS 3.7
rickettsiosis 3.7
DLBCL 3.7
PNET 3.7
Choroid 3.7
retinoschisis 3.7
Choroid 3.7
macular degeneration 3.7
LAP 3.7
AIN 3.7
Bernard-Soulier syndrome 3.6
allergic rhinitis 3.6
atopic dermatitis 3.6
acute arthritis 3.6
Multiple system atrophy 3.6
Marion 3.6
ASM 3.6
inflammatory bowel disease 3.6
CCL 3.6
primitive neuroectodermal tumor 3.6
Nonalcoholic fatty liver 3.6
sepsis 3.6
interstitial cystitis 3.6
Mastitis 3.6
furunculosis 3.5
hydrosalpinx 3.5
Hypertrophic 3.5
SWS 3.5
Opiates 3.5
ABS 3.5
periodontitis 3.5
Chondrosarcoma 3.5
tracheobronchitis 3.5
Chondrosarcoma 3.5
hyperosmolality 3.5
MEC 3.5
CSE 3.5
BDC 3.5
liver fibrosis 3.5
Ischemic stroke 3.5
erysipelas 3.5
CP1 3.5
CEM 3.4
lyssavirus 3.4
Myxoma 3.4
alcoholic hepatitis 3.4
ABS 3.4
Ross River 3.4
Sandhoff disease 3.4
diabetic nephropathy 3.4
Chlamydia 3.4
secondary infection 3.4
LIP 3.3
TAM 3.3
xerophthalmia 3.3
idiopathic pulmonary fibrosis 3.3
ARVD 3.3
ehrlichiosis 3.3
Weil 3.3
protein-losing enteropathy 3.3
acne 3.3
cognitive disorder 3.3
avian leukosis 3.3
acne vulgaris 3.3
TAS 3.3
multicentric Castleman's disease 3.3
B-cell lymphoma 3.3
primitive neuroectodermal tumor 3.3
dermatitis 3.3
sporotrichosis 3.3
pyoderma gangrenosum 3.2
myelosuppression 3.2
Chronic heart failure 3.2
adult AML 3.2
encephalomyelitis 3.2
regional pain syndrome 3.2
dysentery 3.2
Proteinuria 3.2
coxsackievirus 3.2
malignant mesothelioma 3.2
amyotrophic lateral sclerosis 3.2
MIP 3.2
excessive drinking 3.2
virus infection 3.1
acute chest syndrome 3.1
oropharyngeal squamous cell carcinoma 3.1
paracoccidioidomycosis 3.1
amelogenesis imperfecta 3.1
Zinc deficiency 3.1
vitiligo 3.1
lupus nephritis 3.1
Infection 3.1
chromoblastomycosis 3.1
SIRS 3.1
skin ulcers 3.1
alopecia areata 3.1
cystinosis 3.1
cystitis 3.1
streptococcal pharyngitis 3.0
croup 3.0
testicular feminization 3.0
more...
Symptom
Chronic pelvic pain syndrome 7.4
localized erythema 7.4
General symptoms 6.4
peri-menopausal 4.8
male subfertility 4.3
dry eye 3.5
hyperoxia 3.1
despair 2.7
dry skin 2.3
emaciation 2.3
chills 2.2
abnormal gait 2.2
collapse 2.1
memory loss 2.1
arthralgia 1.8
splenomegaly 1.6
hypothermia 1.5
starvation 1.5
respiratory distress 1.5
chorea 1.3
tense 1.2
functional recovery 1.2
exhaustion 1.2
acute stress 1.1
asthenia 0.9
cachexia 0.8
polyuria 0.7
flushing 0.7
diarrhea 0.7
myalgia 0.6
erythema 0.6
anorexia 0.6
cerebellar ataxia 0.5
acidity 0.4
nausea 0.4
acute pain 0.4
pelvic pain 0.3
apathy 0.3
overweight 0.2
distraction 0.1
fatigue 0.1
nausea and vomiting 0.1
vomiting -0.1
seizures -0.1
pain -0.1
headache -0.1
lethargy -0.2
hepatomegaly -0.2
cough -0.2
back pain -0.3
ataxia -0.6
dystonia -0.7
syncope -0.9
dyspnea -0.9
analgesia -0.9
constipation -1.0
abdominal pain -1.0
Ill -1.1
sleepiness -1.3
anesthesia -1.4
chest pain -1.8
angina -2.1
discomfort -2.1
discomfort -2.3
Drug
Mifobate 12.3
Talabostat 10.5
Bv2 9.8
Lexatumumab 9.7
CED 9.5
CA-074 8.5
Platonin 8.4
Rilonacept 8.3
Atractylodes rhizome 8.1
Roferon A 7.9
Ferric ammonium citrate 7.9
Hirudoid 7.5
Adenosine Monophosphate 7.4
Irofulven 7.4
Anakinra 7.3
Peanut oil 7.2
Interferon alfa-2a 6.9
Amlexanox 6.8
Tenidap 6.5
Butaprost 6.4
Tipifarnib 6.2
IL-1ra 6.1
AMC 6.0
Gold sodium thiomalate 6.0
Lipitor 5.9
3-Methyladenine 5.9
Batimastat 5.8
Batimastat 5.8
Immune globulin 5.7
Glybenclamide 5.7
Paliperidone 5.6
Lipitor 5.5
Lipitor 5.5
Auranofin 5.5
Red ginseng 5.4
Pirfenidone 5.4
Idebenone 5.4
Pepstatin 5.4
Clodronate 5.3
Zevalin 5.3
Rhubarb 5.3
Propidium 5.3
Aliskiren 5.3
ROS 5.2
Saha 5.2
Vinpocetine 5.1
Rebamipide 5.1
Tianeptine 5.0
Flavopiridol 4.6
Idarubicin 4.6
Rifaximin 4.6
Tocilizumab 4.6
Rutin 4.5
Epigallocatechin 4.5
IFN-beta 4.3
Compound 9 4.3
Lactase 4.2
Etoposide 4.2
Emodin 4.1
PPA 4.1
Silica gel 4.1
DEX 4.1
Kainic acid 4.0
Mycophenolic acid 3.9
G-CSF 3.9
Glycyrrhiza 3.8
Parkin 3.8
Parkin 3.8
Tannic acid 3.7
Olive oil 3.7
Rosiglitazone 3.6
Cilostazol 3.6
Ginseng 3.6
Propofol 3.6
Aminoguanidine 3.6
IFN-gamma 3.6
Rolipram 3.6
CCL 3.6
Liraglutide 3.5
Adenosine triphosphate 3.5
TTC 3.4
Fludarabine 3.4
Emodin 3.4
CPT-11 3.4
KGF 3.4
PFT 3.4
TAK 3.4
Heme 3.3
Imiquimod 3.3
Orphan 3.2
Donepezil 3.2
TES 3.2
Silica 3.1
Taxotere 3.0
VCR 3.0
R1881 3.0
Arsenic trioxide 3.0
Taxol 3.0
Nitric Oxide 3.0
Alliance 2.9
Phosphatidylserine 2.9
BH4 2.7
p75 2.7
Riboflavin 2.7
CIA 2.7
AGG 2.7
Zoledronic acid 2.7
Irinotecan 2.6
Simvastatin 2.6
APD 2.5
Amoxicillin 2.5
Sodium nitroprusside 2.4
-deoxyadenosine 2.3
ACT 2.2
Paraffin 2.2
Estrogens 2.2
Infliximab 2.2
Infliximab 2.2
Gefitinib 2.1
Aloe 2.1
RFP 2.1
Azithromycin 2.1
Serum albumin 2.0
CSF 2.0
CoCl2 2.0
CoCl2 2.0
Methylene blue 2.0
Pronase 2.0
ETS 1.9
Honey 1.9
NBT 1.9
Lovastatin 1.9
AZT 1.9
BLM 1.9
Alanine 1.9
Rituximab 1.8
Gleevec 1.8
IL-2 1.8
Sorafenib 1.7
AZT 1.7
balanced salt solution 1.7
VCR 1.7
Triclosan 1.7
Ranitidine 1.7
Cimetidine 1.7
TAC 1.6
Acacia 1.6
Cimetidine 1.6
Activin 1.6
PTC 1.5
Docetaxel 1.5
Glutathione 1.5
FAD 1.5
Histamine 1.4
Fluorescein 1.4
Monit 1.4
Ethanol 1.4
Bifidobacterium 1.4
ADR 1.3
Indomethacin 1.3
Dakar 1.2
MDS 1.2
MAP 1.2
Glycerol 1.1
Fragment 1.1
L-tyrosine 1.1
TAT 1.1
Imatinib 1.0
Ouabain 1.0
pyridoxal phosphate 1.0
CTX 1.0
Forskolin 1.0
Spectrum 0.9
HCG 0.9
DNase I 0.9
CTX 0.8
CTX 0.8
CAM 0.8
Asn 0.8
Gel 0.8
CaCl2 0.7
CaCl2 0.7
CaCl2 0.6
Vitamin E 0.6
ampicillin 0.6
MRC 0.6
Kenyan 0.5
Glucagon 0.4
niacin 0.4
lysine 0.4
Spectrum 0.3
Biopolymers 0.3
vitamin E 0.2
ABC 0.2
ZnO 0.2
Adriamycin 0.1
Angiotensin II -0.0
lactose -0.1
Dermatol -0.2
ascorbate -0.2
Mutagen -0.2
Asthma -0.3
Leaf -0.5
EE2 -0.6
THF -0.7
citric acid -1.0
Cardiovasc -1.0
caffeine -1.1
NADH -1.1
Dial -2.6
Enzyme
caspase-1 12.3
caspase-5 11.7
caspase-11 11.5
caspase-5 11.5
caspase-11 11.4
proteinase A 10.6
caspase-4 10.6
caspase-4 10.4
thermomycolase 9.5
meprin B 9.4
Pla 9.0
caspase-6 9.0
adenain 8.7
caspase-6 8.7
caspase-2 8.6
caspase-2 8.6
caspase-10 8.5
caspase-10 8.5
D-cysteine desulfhydrase 8.3
NS protease 8.3
caspase-7 8.2
caspase-7 8.0
streptomycin adenylyltransferase 8.0
streptopain 7.7
caspase-8 7.5
granzyme M 7.4
cathepsin V 7.3
alpha-lytic protease 7.1
cathepsin B 6.9
aspartase 6.9
granzyme K 6.9
cholesterol 25-hydroxylase 6.8
mevalonate kinase 6.7
caspase-3 6.7
deoxyhypusine hydroxylase 6.3
serralysin 6.2
legumain 6.0
TSP-1 5.9
apyrase 5.7
caspase-9 5.7
granzyme B 5.6
RGP 5.5
proteinase-3 5.5
PARP 5.4
xyloglucan endotransglycosylase 5.4
phosphoserine phosphatase 5.2
DNase II 5.1
macrophage elastase 5.1
cathepsin X 5.1
ATP diphosphohydrolase 5.0
deoxyhypusine synthase 5.0
pseudouridine synthase 5.0
nucleoside diphosphokinase 5.0
3C protease 5.0
separase 4.9
Omi/HtrA2 4.9
proteinase A 4.8
meprin 4.8
HK2 4.8
triose-phosphate isomerase 4.8
IKK 4.7
NADPH oxidase 4.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.7
TdT 4.6
NADPH oxidase 4.6
AMPK 4.5
phosphatidylethanolamine N-methyltransferase 4.5
fatty acid desaturase 4.4
clostripain 4.4
cathepsin S 4.3
cathepsin G 4.3
C3b inactivator 4.3
SpeB 4.2
cathepsin L 4.2
conjugase 4.2
fumarylacetoacetate hydrolase 4.1
LIS 4.1
MPP 4.0
thermolysin 4.0
AMP-activated protein kinase 4.0
MsrA 4.0
NAT 3.9
lactate dehydrogenase 3.8
fructokinase 3.8
neutrophil elastase 3.8
cathepsin C 3.7
TACE 3.7
transaldolase 3.7
m-calpain 3.6
mitogen-activated protein kinase 3.6
cathepsin D 3.6
AMPK 3.6
carboxypeptidase Y 3.5
AST 3.5
chymase 3.5
lactic acid dehydrogenase 3.5
topoisomerase 3.5
AMP-activated kinase 3.4
adenosine kinase 3.4
chymosin 3.4
topoisomerase 3.4
interstitial collagenase 3.4
lactic acid dehydrogenase 3.4
HMG-CoA synthase 3.4
glucosylceramide synthase 3.4
MMP-3 3.4
histidine decarboxylase 3.4
RNase III 3.3
angiotensin-converting enzyme 2 3.3
BMT 3.3
CYP27A1 3.2
HtrA 3.2
MIP 3.2
ADPase 3.2
xanthine oxidase 3.2
3-hydroxy-3-methylglutaryl-CoA reductase 3.2
isopeptidase 3.2
proteasome 3.2
myrosinase 3.2
protein phosphatase 2A 3.1
alanine aminotransferase 3.1
xanthine dehydrogenase 3.0
factor C 3.0
PCE 3.0
elastase 3.0
peroxiredoxin 2.9
mu-calpain 2.9
DNA ligase 2.9
DNA ligase 2.9
E-2 2.8
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.8
superoxide dismutase 2.8
soluble epoxide hydrolase 2.8
CEP 2.8
lactic acid dehydrogenase 2.7
ClpP 2.7
aspartate aminotransferase 2.7
NQO1 2.7
MCS 2.7
fructose 1,6-bisphosphatase 2.7
ubiquitin-protein ligase 2.7
ricin 2.7
dihydropyrimidine dehydrogenase 2.6
diamine oxidase 2.6
papain 2.6
luciferase 2.6
NO synthase 2.6
BAT 2.6
12-lipoxygenase 2.6
tryptophan 2,3-dioxygenase 2.6
aconitase 2.5
S-adenosylmethionine decarboxylase 2.5
myosin light chain kinase 2.5
SPT 2.5
cathepsin K 2.5
enolase 2.4
arginase 2.4
GAS 2.4
pepsin 2.4
PRE 2.4
GSK 2.4
ADP-ribosyltransferase 2.3
bromelain 2.3
nucleotidase 2.3
thymidine phosphorylase 2.3
farnesyltransferase 2.3
paraoxonase 2.3
ADP-ribosyltransferase 2.3
MMP 2.3
lactase 2.2
hormone-sensitive lipase 2.2
chymotrypsin 2.2
CEP 2.2
peroxidase 2.2
phosphoinositide 3-kinase 2.1
cdc2 2.1
uricase 2.1
invertase 2.0
dihydropyrimidine dehydrogenase 2.0
MAP 2.0
CPS 2.0
complex I 2.0
protein kinase 2.0
glyceraldehyde-3-phosphate dehydrogenase 2.0
tyrosine hydroxylase 1.9
catalase 1.9
proteinase K 1.9
histone acetyltransferase 1.9
LPL 1.9
MEK 1.9
heme oxygenase 1.9
alpha-glucosidase 1.8
purine nucleoside phosphorylase 1.8
ribonucleotide reductase 1.8
acyl-CoA dehydrogenase 1.8
indoleamine 2,3-dioxygenase 1.8
chitinase 1.8
urease 1.8
TPP 1.8
subtilisin 1.8
glucocerebrosidase 1.8
DAT 1.8
urease 1.8
ribonucleotide reductase 1.8
farnesyltransferase 1.8
reverse transcriptase 1.7
focal adhesion kinase 1.7
deoxyribonuclease 1.7
calcineurin 1.7
Alternating 1.7
transcriptase 1.7
CD10 1.6
PRA 1.6
ACE 1.6
endonuclease 1.6
PTA 1.6
aldolase 1.6
HSD 1.5
trypsin 1.5
glycerol-3-phosphate dehydrogenase 1.5
thymidylate synthase 1.5
glycerol-3-phosphate dehydrogenase 1.5
NOS 1.5
phosphatidylinositol 3-kinase 1.5
MEKK1 1.4
glutathione S-transferase 1.4
DNase 1.4
BAL 1.4
phytase 1.4
phytase 1.3
chondroitinase 1.3
succinate dehydrogenase 1.3
RNase 1.3
ERK 1.3
creatine kinase 1.3
guanylate cyclase 1.3
glutamate decarboxylase 1.2
chaperonin 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
chondroitinase 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
glutathione peroxidase 1.2
matrix metalloproteinase 9 1.2
citrate synthase 1.2
RNase 1.2
collagenase 1.1
matrix metalloproteinase 2 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
phospholipase A2 1.1
TAT 1.1
sucrase 1.1
hypoxanthine-guanine phosphoribosyltransferase 1.0
adenosine deaminase 1.0
protein kinase C 1.0
adenosine deaminase 1.0
SPC 1.0
alpha-amylase 1.0
lipase 0.9
MDP 0.9
sialidase 0.9
asparaginase 0.9
adenylate cyclase 0.9
RNase H 0.9
tryptase 0.9
glyceraldehyde-3-phosphate dehydrogenase 0.8
ATPase 0.8
glucokinase 0.8
acetyl-CoA carboxylase 0.8
lipoxygenase 0.8
thrombin 0.7
phospholipase C 0.7
isocitrate dehydrogenase 0.7
ornithine decarboxylase 0.7
glutathione reductase 0.7
aldose reductase 0.6
isocitrate dehydrogenase 0.6
RNA polymerase 0.5
carbonic anhydrase 0.4
phosphodiesterase 0.4
glucose-6-phosphate dehydrogenase 0.4
ACS 0.4
CaMKII 0.3
APC 0.3
CAD 0.2
MDR 0.2
CAD 0.2
thromboplastin 0.2
CAD 0.2
beta-galactosidase 0.1
kinesin 0.0
pyruvate kinase -0.0
alkaline phosphatase -0.1
glucose oxidase -0.1
demethylase -0.1
phosphorylase -0.1
DNA polymerase -0.2
dihydrofolate reductase -0.2
kallikrein -0.3
hyaluronidase -0.3
aldehyde dehydrogenase -0.4
ribonuclease -0.4
ribonuclease -0.4
P-glycoprotein -0.4
prostate-specific antigen -0.5
ATP synthase -0.5
renin -0.5
neuraminidase -0.5
thymidine kinase -0.6
beta-glucuronidase -0.6
cytochrome oxidase -0.8
plasmin -0.8
urokinase-type plasminogen activator -1.1
lysozyme -1.1
acid phosphatase -1.3
beta-lactamase -1.4
acetylcholinesterase -2.5
Compound
Ginsenoside Rf 10.7
ASC 10.5
Chelidonic acid 10.3
2-methyl-6-undecylpiperidine 10.3
Theasinensin A 10.0
5-Methoxytryptophan 9.7
Nodakenin 9.7
Cucurbitacin D 9.1
CMK 8.9
2-hydroxy-1-propanesulfonic acid 8.8
3,4-pyridinedicarboxylic acid 8.8
1-heptadecene 8.4
Dracorhodin 8.3
Wedelolactone 8.3
Rhaponticin 8.2
Ruscogenin 8.1
Nigericin 7.9
Gedunin 7.8
Micheliolide 7.8
Micheliolide 7.8
Menthone 7.8
DCB 7.6
DCB 7.6
4-phenyl-2-butanone 7.5
LLY 7.5
Sodium hydrosulfide 7.5
Eudesmol 7.4
Propantheline 7.4
DCB 7.4
Diisononyl phthalate 7.4
Mauve 7.4
Androstenediol 7.4
N-acetyltryptophan 7.4
Gentiopicroside 7.4
4-phenyl-2-butanone 7.4
Acacetin 7.3
Aluminum hydroxide 7.3
Loganin 7.3
Merbarone 7.3
Physcion 7.3
Purpurin 7.3
Dihydromyricetin 7.3
Chrysophanol 7.2
Stearidonic acid 7.1
Geranylgeraniol 7.1
DCB 7.1
Chrysophanol 7.1
27-Hydroxycholesterol 7.1
Sinigrin 7.1
DCB 7.0
Aucubin 6.9
TPCK 6.9
AS-101 6.9
TKB 6.9
THP 6.9
THP 6.8
AICA-riboside 6.8
Isoorientin 6.7
Pristimerin 6.6
Pristimerin 6.6
cinnamyl acetate 6.6
Pristimerin 6.6
Pristimerin 6.6
IVE 6.6
Fluocinolone acetonide 6.6
Ziram 6.6
14,15-DHET 6.5
T 12 6.5
Pulegone 6.5
iodic acid 6.5
EGT 6.4
Gadolinium chloride 6.4
Pelargonidin 6.4
Harmine 6.4
L-chicoric acid 6.4
Triphosphate 6.4
Liquiritigenin 6.3
10-Hydroxycamptothecin 6.3
Alum 6.3
Garcinol 6.2
Benzamidine 6.1
Sinomenine 6.1
Dolichol 6.1
Bilobalide 6.1
Nerolidol 6.1
Vanillic acid 6.0
Nerolidol 6.0
Z-Gly-Pro 6.0
D-Galactosamine 6.0
Isoliquiritigenin 5.9
3-Methyladenine 5.9
Paeonol 5.9
Cinnamaldehyde 5.9
Shikonin 5.9
Brilliant Blue 5.9
Ifosfamide 5.9
Withaferin A 5.8
Etorphine 5.8
Rhein 5.8
Cepharanthine 5.8
Glibenclamide 5.8
Dioscin 5.8
Dioscin 5.8
HEI 5.7
25-Hydroxycholesterol 5.7
Dexmedetomidine 5.7
Latrunculin B 5.7
Natamycin 5.7
Genipin 5.6
Diallyl disulfide 5.6
Hyperoside 5.6
Diallyl disulfide 5.6
Oridonin 5.6
Fluvastatin 5.6
NIX 5.5
Celastrol 5.5
Allicin 5.5
DHM 5.5
DOD 5.5
celastrol 5.5
Ethyl pyruvate 5.5
Asiatic acid 5.4
Juglone 5.4
Thymoquinone 5.4
Mangiferin 5.4
Dibucaine 5.4
Cuprizone 5.4
Matrine 5.4
Matrine 5.4
Matrine 5.4
isonicotinamide 5.4
Cytochalasin D 5.4
Galangin 5.3
Sulforaphane 5.3
AFC 5.3
9H-xanthen-9-one 5.3
Catalpol 5.3
Taxifolin 5.3
Gambogic acid 5.3
Formononetin 5.3
BzATP 5.3
Rifamycin 5.2
Evodiamine 5.2
PIPES 5.2
PIPES 5.2
Polydatin 5.2
PIPES 5.2
Staurosporine 5.2
Dimethyl fumarate 5.2
Iodoacetamide 5.2
Biochanin A 5.2
Morin 5.1
Evodiamine 5.1
Phloretin 5.1
Staurosporine 5.1
Paeoniflorin 5.1
Cordycepin 5.1
Cordycepin 5.1
Cordycepin 5.1
6-Gingerol 5.1
Surfactin 5.1
benzenesulfonyl fluoride 5.1
BayK8644 5.0
Geniposide 5.0
Palmitoleic acid 5.0
dUTP 5.0
TTNPB 5.0
Uric acid 5.0
Acteoside 5.0
Phorbol-12-myristate-13-acetate 5.0
Baicalin 5.0
1,3-butanediol 4.9
Zirconia 4.9
Geraniol 4.9
Nocodazole 4.9
Thiram 4.9
Glycyrrhetinic acid 4.9
HAP 4.8
Palmitic acid 4.8
TNF 4.8
BAF 4.8
1,3-butanediol 4.8
Nobiletin 4.8
Pterostilbene 4.8
MNT 4.8
Geraniol 4.8
Asp 4.8
Thiram 4.7
8-hydroxyguanosine 4.7
Cinnamic acid 4.7
Epirubicin 4.7
DBP 4.6
Aristolochic acid 4.6
Lentinan 4.6
Arecoline 4.6
Magnolol 4.6
Hemin 4.6
Hemin 4.6
Hemin 4.6
Hemin 4.6
Tauroursodeoxycholic acid 4.6
Glycyrrhetinic acid 4.6
11,12-EET 4.5
DEX 4.5
Acrolein 4.5
DCI 4.5
Rutin 4.5
N-acetylcysteine 4.5
Glycolate 4.5
isopentane 4.5
Lipoxin A4 4.5
DSS 4.5
Hemin 4.4
Minocycline 4.4
Rottlerin 4.4
DPI 4.4
Pepstatin 4.4
Salmeterol 4.4
2,5-hexanedione 4.4
VP-16 4.4
ADP-ribose 4.4
FTA 4.4
Tanshinone 4.3
Busulfan 4.3
Geldanamycin 4.3
benzohydrazide 4.3
Rottlerin 4.3
4-Hydroxynonenal 4.3
Rottlerin 4.3
Beryllium 4.3
leucine 4.3
BIP 4.3
3,4-Methylenedioxymethamphetamine 4.2
Rotenone 4.2
Rhodamine 123 4.2
Docosahexaenoic acid 4.2
Chalcone 4.2
Leupeptin 4.2
PCMB 4.2
PCMB 4.2
PCMB 4.2
MPP 4.1
Doxazosin 4.1
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 4.1
Calcium carbonate 4.1
Betulinic acid 4.1
MPP 4.1
PCMB 4.1
Chrysin 4.1
Valinomycin 4.1
Leucine 4.1
Apocynin 4.1
Probenecid 4.1
NPR 4.0
BEP 4.0
3-aminobenzamide 4.0
MVA 4.0
E-64 4.0
Honokiol 4.0
Thiabendazole 4.0
Hesperidin 4.0
POP 4.0
NKT 4.0
Tempol 4.0
Statin 4.0
Perfluorooctanoic acid 4.0
Rosmarinic acid 4.0
Rosmarinic acid 4.0
Edaravone 4.0
Kainic acid 4.0
Kainic acid 4.0
APO 3.9
Hoechst 33342 3.9
cysteine 3.9
BHA 3.9
Sitosterol 3.9
AGE 3.9
Piperine 3.9
Meloxicam 3.9
HBA 3.9
NBC 3.9
6-aminonicotinamide 3.9
Colchicine 3.9
PPA 3.9
Asbestos 3.9
aldehyde 3.8
Sevoflurane 3.8
Leupeptin 3.8
PMSF 3.8
Paclitaxel 3.8
Xanthine 3.8
Microcystin-LR 3.8
tellurium 3.8
Emodin 3.8
DBM 3.8
Patulin 3.8
DLT 3.8
Hematoxylin 3.8
DBM 3.8
MPTP 3.8
TBI 3.8
Metformin 3.8
Epigallocatechin 3.7
Metformin 3.7
ATP 3.7
Ursolic acid 3.7
Prone 3.7
K19 3.7
Actinomycin D 3.7
Topotecan 3.7
Nonylphenol 3.7
Agmatine 3.6
Cer 3.6
Ritonavir 3.6
TACE 3.6
Berberine 3.6
TES 3.6
Naringenin 3.6
dATP 3.6
Brefeldin A 3.6
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