Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.36 (caspase-1)
 6,285 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ICE 0.167
NLRP3 0.082
IL-18 0.041
ASC 0.032
pyrin 0.029
Caspase-1 0.021
AIM2 0.019
NLRC4 0.018
gasdermin D 0.010
apoptosis-associated speck-like protein containing a CARD 0.009
NLRP1 0.007
CPP32 0.006
GSDMD 0.004
NALP3 0.003
NOD 0.003
gasdermin 0.003
interleukin-18 0.003
NLRP3 protein 0.003
NLRP6 0.002
NALP1 0.002
IPAF 0.002
caspase-3 0.002
IL-1 0.001
p20 0.001
CED 0.001
ICEBERG 0.001
caspase-8 0.001
CASP1 0.001
TXNIP 0.001
P2X7 0.001
cytokine 0.001
CMK 0.001
NEK7 0.001
THP 0.001
AII 0.001
cysteine protease 0.001
p10 0.001
LPS 0.001
pyrin domain containing 1 0.001
Fas 0.001
CARD8 0.001
TMS1 0.001
adaptor protein 0.001
TLR4 0.001
NLRP12 0.000
IL18 0.000
NLRP10 0.000
NAIP 0.000
lipopolysaccharide 0.000
RIP2 0.000
cathepsin B 0.000
CIAS1 0.000
NLR family, pyrin domain containing 3 0.000
PYPAF2 0.000
CARD12 0.000
AIM2 protein 0.000
IL-6 0.000
interleukin 18 0.000
caspase 2 0.000
TNF 0.000
ICH-2 0.000
HIPPI 0.000
IL-33 0.000
poly(ADP-ribose) polymerase 0.000
Interleukin-18 0.000
thymic stromal lymphopoietin 0.000
CASP-1 0.000
NIMA-related kinase 7 0.000
PYPAF7 0.000
NALP2 0.000
FLICE 0.000
MyD88 0.000
Bcl-2 0.000
ICH3 0.000
NLRP11 0.000
ILPIP 0.000
Ly6/PLAUR domain-containing protein 6 0.000
DAGD 0.000
caspase and RIP adapter with death domain 0.000
toll-like receptor adaptor molecule 2 0.000
CMH1 0.000
leucine-rich repeat-containing 3 0.000
NLRP7 0.000
caspase 4 0.000
CMH-1 0.000
TLR2 0.000
PARP 0.000
tumor necrosis factor 0.000
leucine-rich-repeat protein 0.000
ROS 0.000
ICH-1L 0.000
IL1B 0.000
APO-1 0.000
NLRP2 0.000
PYPAF3 0.000
NLRP13 0.000
transmembrane protein 176B 0.000
IGLL3 0.000
guanylate binding protein 4 0.000
Ras-related protein Rab-37 0.000
USP50 0.000
GIG4 0.000
Tripartite motif-containing protein 31 0.000
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor 0.000
IFI16 0.000
P2X purinoceptor 7 0.000
CD95 0.000
Fas ligand 0.000
IL-1F7 0.000
HMGB1 0.000
RIP3 0.000
ATP 0.000
RAIDD 0.000
GBP5 0.000
Nod1 0.000
RAB39A 0.000
protease E) 0.000
CAGE1 0.000
NLRP1 protein 0.000
cPOP2 0.000
DDX19A 0.000
interacting protein 0.000
leucine-rich repeat protein 0.000
RIPK3 0.000
ASC-1 0.000
POP3 0.000
MEFV 0.000
FADD 0.000
p65 0.000
IL-1F6 0.000
IL-1 beta 0.000
Pannexin-1 0.000
NLRC3 0.000
bcl-2 0.000
Chemokine (C-C motif) ligand 3 0.000
caspase-9 0.000
MLKL 0.000
ASC2 0.000
BRCC3 0.000
PSTPIP2 0.000
caspase-14 0.000
THP1 0.000
ATP receptor 0.000
caspase 6 0.000
NOD2 0.000
APIP 0.000
P2X 0.000
EIF-5A 0.000
TNFRSF1A-associated via death domain 0.000
IFN 0.000
caspase 7 0.000
NLRP9 0.000
neuronal apoptosis inhibitory protein 0.000
adapter protein 0.000
POP1 0.000
RFC140 0.000
INCA 0.000
RIPK1 0.000
NLRP8 0.000
TNF receptor-associated factor 4 0.000
more...
Disease
NOD 0.003
Muckle-Wells syndrome 0.000
CMH1 0.000
Oral pemphigus vulgaris 0.000
gout 0.000
Non-bacterial prostatitis 0.000
Chronic skin disease 0.000
cowpox 0.000
familial Mediterranean fever 0.000
POF4 0.000
Alcoholic liver damage 0.000
Mevalonate kinase deficiency 0.000
anthrax 0.000
bacterial infection 0.000
colitis 0.000
Legionella 0.000
sepsis 0.000
Gouty arthritis 0.000
sepsis 0.000
ICE syndrome 0.000
Acute glaucoma 0.000
NOMID 0.000
Vaccinia virus infection 0.000
Pulmonary fat embolism 0.000
Dissecting aortic aneurysm 0.000
atherosclerosis 0.000
peritonitis 0.000
bacillary dysentery 0.000
MYP3 0.000
Sepsis-associated encephalopathy 0.000
Shigella 0.000
Macular corneal dystrophy 0.000
ischemia 0.000
Shigella flexneri 0.000
Yersinia 0.000
diabetic cardiomyopathy 0.000
virus infection 0.000
cerebral ischemia 0.000
salmonellosis 0.000
infectious diseases 0.000
DFNA5 0.000
CINCA syndrome 0.000
endotoxic shock 0.000
cancer 0.000
inflammatory bowel disease 0.000
Therapy-related myelodysplastic syndrome 0.000
Alzheimer's disease 0.000
Blocking 0.000
pseudotuberculosis 0.000
Infection 0.000
gouty nephropathy 0.000
malignant myeloma 0.000
tumor 0.000
maple syrup urine disease 0.000
Geographic atrophy 0.000
DSS 0.000
CPS deficiency 0.000
tularemia 0.000
rhabdoid tumor of the kidney 0.000
WTS 0.000
type 2 diabetes 0.000
Viral myocarditis 0.000
Aortic atherosclerosis 0.000
Parvovirus infection 0.000
immunopathology 0.000
Pulmonary eosinophilia 0.000
monocytic leukemia 0.000
DSS 0.000
atopic dermatitis 0.000
Leishmania braziliensis infection 0.000
Intestinal ischemia 0.000
Diabetic encephalopathy 0.000
bacterial dysentery 0.000
rheumatoid arthritis 0.000
tumorigenesis 0.000
Hereditary tyrosinemia type I 0.000
obesity 0.000
diabetes 0.000
periodontitis 0.000
pneumonia 0.000
B-cell lymphoma 0.000
arthritis 0.000
amyotrophic lateral sclerosis 0.000
diabetic retinopathy 0.000
alcoholic fatty liver 0.000
Neonatal infection 0.000
multiple sclerosis 0.000
Chlamydia 0.000
cold 0.000
Mycobacterium 0.000
Streptococcus pneumoniae meningitis 0.000
West Nile encephalitis 0.000
placental disorders 0.000
leukemia 0.000
Histoplasma capsulatum infection 0.000
FCU 0.000
Crescentic glomerulonephritis 0.000
dermatitis 0.000
psoriasis 0.000
hyperuricemia 0.000
Influenza A virus infection 0.000
allergic rhinitis 0.000
Apical periodontitis 0.000
macular degeneration 0.000
trichophytosis 0.000
diabetic nephropathy 0.000
Critically Ill 0.000
legionellosis 0.000
renal ischemia 0.000
encephalomyelitis 0.000
Klebsiella pneumoniae infection 0.000
favus 0.000
Lumbar disc herniation 0.000
Aspergillus fumigatus infection 0.000
stroke 0.000
Submandibular gland 0.000
neuroblastoma 0.000
PAPA 0.000
liver fibrosis 0.000
Parasitic infection 0.000
Middle cerebral artery occlusion 0.000
GSH 0.000
vascular ischemia 0.000
Prostate tumor 0.000
Age-related macular degeneration 0.000
genital infection 0.000
asthma 0.000
Chronic inflammatory demyelinating polyradiculoneuropathy 0.000
Parkinson's disease 0.000
Irritant contact dermatitis 0.000
aggressive lymphoma 0.000
ulcerative colitis 0.000
cough variant asthma 0.000
cognitive impairment 0.000
Candida sepsis 0.000
brain edema 0.000
enterocolitis 0.000
hepatocellular carcinoma 0.000
Crohn's disease 0.000
Burkitt-like lymphoma 0.000
FAS 0.000
tuberculosis 0.000
Pulmonary infiltrates 0.000
Prosthetic valve endocarditis 0.000
melanoma 0.000
AML progression 0.000
influenza 0.000
dental abscess 0.000
chronic obstructive pulmonary disease 0.000
Oral infection 0.000
Brucella abortus 0.000
melioidosis 0.000
PCD 0.000
closed angle glaucoma 0.000
hyperhomocysteinemia 0.000
Diarrheal disease 0.000
Fungal keratitis 0.000
testicular dysfunction 0.000
Schnitzler syndrome 0.000
Ureteral obstruction 0.000
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Symptom
Chronic pelvic pain syndrome 0.000
localized erythema 0.000
General symptoms 0.000
collapse 0.000
peri-menopausal 0.000
hyperoxia 0.000
dry eye 0.000
male subfertility 0.000
starvation 0.000
pain 0.000
respiratory distress 0.000
hypothermia 0.000
diarrhea 0.000
chills 0.000
despair 0.000
arthralgia 0.000
splenomegaly 0.000
memory loss 0.000
dry skin 0.000
emaciation 0.000
functional recovery 0.000
exhaustion 0.000
abnormal gait 0.000
seizures 0.000
fatigue 0.000
headache 0.000
nausea 0.000
acute stress 0.000
erythema 0.000
chorea 0.000
overweight 0.000
tense 0.000
anorexia 0.000
acidity 0.000
cachexia 0.000
vomiting 0.000
asthenia 0.000
flushing 0.000
myalgia 0.000
polyuria 0.000
cerebellar ataxia 0.000
cough 0.000
acute pain 0.000
pelvic pain 0.000
apathy 0.000
distraction 0.000
nausea and vomiting 0.000
back pain 0.000
anesthesia 0.000
lethargy 0.000
hepatomegaly 0.000
dyspnea 0.000
analgesia 0.000
ataxia 0.000
abdominal pain 0.000
dystonia 0.000
syncope 0.000
constipation 0.000
Ill 0.000
sleepiness 0.000
chest pain 0.000
angina 0.000
discomfort 0.000
discomfort 0.000
Drug
CED 0.002
Mifobate 0.000
ROS 0.000
Talabostat 0.000
CA-074 0.000
Bv2 0.000
Lexatumumab 0.000
Anakinra 0.000
IL-1ra 0.000
Platonin 0.000
Rilonacept 0.000
AMC 0.000
Atractylodes rhizome 0.000
Ferric ammonium citrate 0.000
Roferon A 0.000
IFN-gamma 0.000
Hirudoid 0.000
Adenosine Monophosphate 0.000
Irofulven 0.000
Peanut oil 0.000
Interferon alfa-2a 0.000
Amlexanox 0.000
Tenidap 0.000
Butaprost 0.000
IFN-beta 0.000
Tipifarnib 0.000
3-Methyladenine 0.000
Gold sodium thiomalate 0.000
G-CSF 0.000
Lipitor 0.000
Auranofin 0.000
Batimastat 0.000
Batimastat 0.000
Immune globulin 0.000
Glybenclamide 0.000
Pirfenidone 0.000
Paliperidone 0.000
Lipitor 0.000
Lipitor 0.000
Clodronate 0.000
Propidium 0.000
Aliskiren 0.000
Red ginseng 0.000
Idebenone 0.000
Pepstatin 0.000
Zevalin 0.000
Rhubarb 0.000
Saha 0.000
Vinpocetine 0.000
Rebamipide 0.000
Tianeptine 0.000
Rutin 0.000
Etoposide 0.000
CSF 0.000
Tocilizumab 0.000
Epigallocatechin 0.000
Parkin 0.000
Parkin 0.000
Flavopiridol 0.000
Idarubicin 0.000
Rifaximin 0.000
Glycyrrhiza 0.000
DEX 0.000
Propofol 0.000
Heme 0.000
Compound 9 0.000
Emodin 0.000
PPA 0.000
Ginseng 0.000
IL-2 0.000
Lactase 0.000
Kainic acid 0.000
Silica gel 0.000
TTC 0.000
CPT-11 0.000
CCL 0.000
Mycophenolic acid 0.000
Taxol 0.000
Rosiglitazone 0.000
Silica 0.000
Tannic acid 0.000
Monit 0.000
Adenosine triphosphate 0.000
Olive oil 0.000
Cilostazol 0.000
Nitric Oxide 0.000
Aminoguanidine 0.000
Alliance 0.000
Rolipram 0.000
p75 0.000
Liraglutide 0.000
TAK 0.000
Fludarabine 0.000
Dermatol 0.000
Emodin 0.000
KGF 0.000
PFT 0.000
Imiquimod 0.000
Orphan 0.000
Donepezil 0.000
TES 0.000
Arsenic trioxide 0.000
Taxotere 0.000
VCR 0.000
R1881 0.000
Phosphatidylserine 0.000
BH4 0.000
Simvastatin 0.000
Riboflavin 0.000
CIA 0.000
AGG 0.000
Zoledronic acid 0.000
Irinotecan 0.000
APD 0.000
Amoxicillin 0.000
lysine 0.000
-deoxyadenosine 0.000
ACT 0.000
Paraffin 0.000
Sodium nitroprusside 0.000
MAP 0.000
Estrogens 0.000
Ethanol 0.000
Infliximab 0.000
Infliximab 0.000
ETS 0.000
AZT 0.000
Gefitinib 0.000
Aloe 0.000
RFP 0.000
Azithromycin 0.000
Serum albumin 0.000
Alanine 0.000
CoCl2 0.000
CoCl2 0.000
Rituximab 0.000
Methylene blue 0.000
Pronase 0.000
Honey 0.000
NBT 0.000
Lovastatin 0.000
Glutathione 0.000
BLM 0.000
AZT 0.000
FAD 0.000
Histamine 0.000
Gleevec 0.000
Bifidobacterium 0.000
Sorafenib 0.000
balanced salt solution 0.000
Indomethacin 0.000
VCR 0.000
Triclosan 0.000
Ranitidine 0.000
Cimetidine 0.000
TAC 0.000
CTX 0.000
Acacia 0.000
Gel 0.000
Cimetidine 0.000
more...
Enzyme
caspase-1 1.000
caspase-11 0.017
caspase-11 0.017
caspase-4 0.005
caspase-5 0.005
caspase-4 0.005
caspase-5 0.005
proteinase A 0.004
caspase-3 0.002
Pla 0.001
caspase-8 0.001
caspase-2 0.001
caspase-6 0.001
caspase-2 0.001
caspase-6 0.001
caspase-7 0.001
caspase-7 0.000
cathepsin B 0.000
caspase-10 0.000
caspase-10 0.000
PARP 0.000
caspase-9 0.000
mitogen-activated protein kinase 0.000
meprin B 0.000
thermomycolase 0.000
granzyme B 0.000
adenain 0.000
NADPH oxidase 0.000
NADPH oxidase 0.000
lactate dehydrogenase 0.000
D-cysteine desulfhydrase 0.000
NS protease 0.000
mevalonate kinase 0.000
apyrase 0.000
streptomycin adenylyltransferase 0.000
aspartase 0.000
streptopain 0.000
alpha-lytic protease 0.000
TSP-1 0.000
cathepsin V 0.000
IKK 0.000
AMP-activated protein kinase 0.000
AMPK 0.000
granzyme M 0.000
superoxide dismutase 0.000
proteasome 0.000
legumain 0.000
granzyme K 0.000
cholesterol 25-hydroxylase 0.000
alanine aminotransferase 0.000
AMPK 0.000
deoxyhypusine hydroxylase 0.000
luciferase 0.000
serralysin 0.000
peroxidase 0.000
TdT 0.000
protein kinase 0.000
topoisomerase 0.000
topoisomerase 0.000
proteinase-3 0.000
RGP 0.000
aspartate aminotransferase 0.000
DNase II 0.000
AST 0.000
cathepsin G 0.000
neutrophil elastase 0.000
xyloglucan endotransglycosylase 0.000
3C protease 0.000
cathepsin L 0.000
catalase 0.000
xanthine oxidase 0.000
phosphoserine phosphatase 0.000
cathepsin D 0.000
meprin 0.000
HK2 0.000
macrophage elastase 0.000
cathepsin X 0.000
separase 0.000
MPP 0.000
Omi/HtrA2 0.000
thermolysin 0.000
ATP diphosphohydrolase 0.000
deoxyhypusine synthase 0.000
NO synthase 0.000
pseudouridine synthase 0.000
elastase 0.000
nucleoside diphosphokinase 0.000
ERK 0.000
fatty acid desaturase 0.000
proteinase A 0.000
triose-phosphate isomerase 0.000
focal adhesion kinase 0.000
MIP 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
MMP-3 0.000
cathepsin S 0.000
phosphatidylethanolamine N-methyltransferase 0.000
clostripain 0.000
C3b inactivator 0.000
reverse transcriptase 0.000
trypsin 0.000
SpeB 0.000
conjugase 0.000
fumarylacetoacetate hydrolase 0.000
NAT 0.000
BMT 0.000
NQO1 0.000
LIS 0.000
papain 0.000
carboxypeptidase Y 0.000
MsrA 0.000
chymase 0.000
protein phosphatase 2A 0.000
pepsin 0.000
TACE 0.000
chymotrypsin 0.000
m-calpain 0.000
fructokinase 0.000
histidine decarboxylase 0.000
MEK 0.000
cathepsin C 0.000
transaldolase 0.000
tyrosine hydroxylase 0.000
adenosine kinase 0.000
interstitial collagenase 0.000
peroxiredoxin 0.000
GSK 0.000
DNA ligase 0.000
DNA ligase 0.000
RNase III 0.000
ATPase 0.000
angiotensin-converting enzyme 2 0.000
lactic acid dehydrogenase 0.000
AMP-activated kinase 0.000
chymosin 0.000
calcineurin 0.000
lactic acid dehydrogenase 0.000
HMG-CoA synthase 0.000
glucosylceramide synthase 0.000
protein kinase C 0.000
3-hydroxy-3-methylglutaryl-CoA reductase 0.000
ACE 0.000
ricin 0.000
endonuclease 0.000
cdc2 0.000
glutathione S-transferase 0.000
CYP27A1 0.000
HtrA 0.000
ADPase 0.000
xanthine dehydrogenase 0.000
complex I 0.000
soluble epoxide hydrolase 0.000
isopeptidase 0.000
myrosinase 0.000
PCE 0.000
enolase 0.000
arginase 0.000
MAP 0.000
diamine oxidase 0.000
factor C 0.000
more...
Compound
ASC 0.032
THP 0.001
THP 0.001
CMK 0.001
TNF 0.000
Asp 0.000
ATP 0.000
Chelidonic acid 0.000
leucine 0.000
DCB 0.000
Ginsenoside Rf 0.000
DCB 0.000
oxygen 0.000
DCB 0.000
cysteine 0.000
2-methyl-6-undecylpiperidine 0.000
DCB 0.000
Theasinensin A 0.000
DCB 0.000
Nodakenin 0.000
5-Methoxytryptophan 0.000
Nigericin 0.000
DNA 0.000
Cucurbitacin D 0.000
dUTP 0.000
2-hydroxy-1-propanesulfonic acid 0.000
3,4-pyridinedicarboxylic acid 0.000
TPCK 0.000
Wedelolactone 0.000
1-heptadecene 0.000
Dracorhodin 0.000
N-acetylcysteine 0.000
Rhaponticin 0.000
alanine 0.000
Ruscogenin 0.000
Dihydromyricetin 0.000
potassium 0.000
Gedunin 0.000
Glibenclamide 0.000
Menthone 0.000
Micheliolide 0.000
Micheliolide 0.000
Aluminum hydroxide 0.000
aldehyde 0.000
Alum 0.000
Sodium hydrosulfide 0.000
N-acetyltryptophan 0.000
serine 0.000
Acacetin 0.000
4-phenyl-2-butanone 0.000
LLY 0.000
Loganin 0.000
Eudesmol 0.000
Propantheline 0.000
Mauve 0.000
Diisononyl phthalate 0.000
Androstenediol 0.000
Chrysophanol 0.000
Gentiopicroside 0.000
4-phenyl-2-butanone 0.000
aldehyde 0.000
Chrysophanol 0.000
Brilliant Blue 0.000
nitric oxide 0.000
Dexmedetomidine 0.000
Purpurin 0.000
Merbarone 0.000
Physcion 0.000
ADP-ribose 0.000
Geranylgeraniol 0.000
Stearidonic acid 0.000
DBP 0.000
Sinigrin 0.000
27-Hydroxycholesterol 0.000
glucose 0.000
Ifosfamide 0.000
Aucubin 0.000
AS-101 0.000
TKB 0.000
IVE 0.000
AICA-riboside 0.000
Isoorientin 0.000
Dec 0.000
celastrol 0.000
cinnamyl acetate 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
Harmine 0.000
Staurosporine 0.000
Triphosphate 0.000
Fluocinolone acetonide 0.000
Ziram 0.000
tyrosine 0.000
14,15-DHET 0.000
Uric acid 0.000
Staurosporine 0.000
T 12 0.000
iodic acid 0.000
Pulegone 0.000
calcium 0.000
HEI 0.000
Gadolinium chloride 0.000
EGT 0.000
Pelargonidin 0.000
Sulforaphane 0.000
L-chicoric acid 0.000
AFC 0.000
Cinnamaldehyde 0.000
VP-16 0.000
Liquiritigenin 0.000
Shikonin 0.000
Sinomenine 0.000
10-Hydroxycamptothecin 0.000
Dolichol 0.000
Rhein 0.000
Cytochalasin D 0.000
Vanillic acid 0.000
DSS 0.000
Garcinol 0.000
Benzamidine 0.000
Isoliquiritigenin 0.000
3-Methyladenine 0.000
Paeonol 0.000
Bilobalide 0.000
Nerolidol 0.000
aspartic acid 0.000
Nerolidol 0.000
aspartic acid 0.000
Z-Gly-Pro 0.000
Withaferin A 0.000
Fluvastatin 0.000
aspartic acid 0.000
D-Galactosamine 0.000
Celastrol 0.000
aspartic acid 0.000
Thymoquinone 0.000
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 0.000
sulfate 0.000
acetate 0.000
Etorphine 0.000
Genipin 0.000
sodium 0.000
Oridonin 0.000
MPTP 0.000
Cepharanthine 0.000
Dioscin 0.000
Dioscin 0.000
25-Hydroxycholesterol 0.000
GSH 0.000
GSH 0.000
Allicin 0.000
BzATP 0.000
Latrunculin B 0.000
Natamycin 0.000
Hyperoside 0.000
Diallyl disulfide 0.000
Diallyl disulfide 0.000
Mangiferin 0.000
more...