Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.32 (bromelain)
 1,025 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
glioma tumor suppressor candidate region gene 2 14.9
regulator of G-protein signalling 13 14.9
C7orf60 14.9
C6orf62 13.9
C15orf32 13.3
glutathione S-transferase mu 2 12.3
GP180 11.8
otopetrin 1 11.6
cysteine dioxygenase type 1 11.6
KIFAP3 11.2
TMEM59 11.2
sortilin 1 11.1
protein tyrosine phosphatase receptor type D 11.0
COPS2 11.0
muCANP 10.8
nuclear receptor coactivator 4 10.0
CD5 molecule 9.8
HA2 9.7
KAP3 9.7
cysteine proteinase inhibitor 9.7
mCANP 9.6
germ cell alkaline phosphatase 9.4
ribosomal protein L29 9.4
DORA 9.3
Gamma-glutamyl transpeptidase 9.3
FBXO11 9.1
cysteine proteinase 9.1
p76 9.0
NB2 9.0
Carboxypeptidase A 8.8
cathepsin V 8.8
PTMA 8.8
calcium-activated neutral protease 8.7
Prolyl endopeptidase 8.7
SAP-1 8.6
cystatin S 8.5
HA1 8.5
anionic trypsinogen 8.4
cathepsin C 8.4
UTF1 8.4
plasma prekallikrein 8.3
DCT1 8.3
A121 8.3
placental-like alkaline phosphatase 8.3
soluble CD44 8.2
cysteine endopeptidase 8.1
mitoNEET 8.1
cathepsin B1 8.1
GREM1 8.1
WD-repeat protein 8.0
30K) 8.0
FIP 8.0
CD44 protein 7.9
cathepsin H 7.9
wts 7.9
neurosin 7.9
chymotrypsin 7.8
Hageman factor 7.7
cysteine protease 7.7
PRX 7.7
IgL 7.7
angiotensin I-converting enzyme 7.7
unknown specificity 7.5
OSP 7.5
Chymotrypsin 7.5
X mRNA 7.5
FBA 7.4
eIF5A 7.4
MCG 7.3
prostaglandin-endoperoxide synthase 2 7.3
CPI 7.2
endo-beta-N-acetylglucosaminidase 7.2
p64 7.2
cathepsin B 7.1
Rh D 7.1
GPIX 7.1
HC2 7.0
ED3 7.0
cystatin A 7.0
GALT 7.0
more...
Disease
Perennial allergic rhinitis 11.2
RP19 11.1
digestive system cancer 8.6
Irritant contact dermatitis 8.3
FIP 8.0
ED3 7.9
FA2 7.7
Schmitz 7.7
Clostridium difficile colitis 7.5
FIP 7.5
USH2A 7.4
Goldblatt hypertension 7.3
Lequesne 7.2
reticuloendotheliosis 7.2
pseudomyxoma peritonei 7.1
pleurisy 7.1
BCM 7.0
GALT 6.6
Arthus reaction 6.2
avian sarcoma 6.2
Atopic 6.2
autoimmune hemolytic anemia 6.1
VPI 6.1
Glanzmann's thrombasthenia 6.1
HPC 6.0
threatened abortion 5.9
trismus 5.8
HPP 5.7
FDC 5.5
influenza 5.4
lactose intolerance 5.4
monocytic leukemia 5.4
roundworm 5.3
nephrosclerosis 5.2
PAA 5.2
SDS 5.2
rind 5.1
Cholangiocarcinoma 5.1
mucinous carcinoma 5.0
Cholangiocarcinoma 5.0
chronic sinusitis 5.0
Spleen 5.0
bronchitis 4.9
protein deficiency 4.9
bronchitis 4.8
plaque 4.7
EL4 4.7
thrombophlebitis 4.7
Appendix 4.6
Appendix 4.6
Appendix 4.6
Hymenolepis 4.5
Hereditary angioedema 4.5
hypergammaglobulinemia 4.5
African trypanosomiasis 4.4
pancreatic insufficiency 4.3
lymphocytic choriomeningitis 4.3
CCD 4.3
antiphospholipid syndrome 4.3
Proteinuria 4.2
colibacillosis 4.2
CCD 4.2
calcinosis 4.1
Plaque 4.1
babesiosis 4.0
DBA 3.9
lymphoproliferative disorders 3.9
Osteosarcoma 3.8
Osteosarcoma 3.8
ichthyosis 3.8
AGS 3.8
THC 3.8
gastrointestinal cancer 3.8
mesothelioma 3.7
cryptosporidiosis 3.7
Newcastle disease 3.7
Thymus 3.6
Thymus 3.6
Thymus 3.6
hemolytic anemia 3.6
more...
Symptom
infant diarrhea 8.2
autodigestion 6.6
Tenderness 6.4
persistent cough 5.7
bitter taste 5.5
joint stiffness 4.9
nasal congestion 4.8
nasal discharge 4.5
sneezing 4.0
rhinorrhea 3.8
knee pain 3.5
memory loss 3.1
numbness 2.6
agitation 2.4
acidity 2.0
low back pain 1.6
angina 1.6
thinning 1.5
pain 1.5
diarrhea 1.4
erythema 1.2
stigma 1.2
exhaustion 1.2
fatigue 0.8
discomfort 0.5
nausea 0.4
discomfort 0.3
analgesia 0.1
abdominal pain -0.0
anesthesia -1.8
Drug
Bromelain 14.4
Protein hydrolysate 11.7
Travase 11.5
RPH 10.1
Papain 9.9
Pancrease 9.5
Sulfamylon 9.4
Dodecyl Sulfate 8.8
Trifluoroethanol 8.7
Lysostaphin 8.5
Kaolin 8.0
Etodolac 7.9
3-Methyladenine 7.5
Pronase 7.2
Guanidine 6.5
Guanidine 6.5
Gelatin 6.2
Ginger 6.0
AMC 5.7
Urokinase 5.6
CFS 5.6
Tocopherol 5.5
Fraction 5.2
Asn 5.1
Aprotinin 5.1
CTC 4.9
Lactose 4.8
Captopril 4.8
MRC 4.8
Aloe 4.7
CTC 4.6
CTA 4.5
PTC 4.2
uPA 3.9
L-tyrosine 3.7
ascorbate 3.6
Forskolin 3.6
Alanine 3.5
CAM 3.4
vitamin E 3.4
Vitamin A 3.4
CaCl2 3.3
CaCl2 3.3
CaCl2 3.2
Vitamin E 3.2
Gel 3.1
lactose 2.9
lysine 2.9
Biopolymers 2.9
IFN-gamma 2.7
IL-2 2.7
Ethanol 2.7
FAD 2.5
EPA 2.1
nitroglycerin 1.8
citric acid 1.7
caffeine 1.5
Leaf 1.5
MAP 1.0
ampicillin 0.9
ROS 0.7
NADH 0.5
Dial 0.0
Dermatol -0.8
Enzyme
bromelain 14.9
stem bromelain 14.8
ficin 13.0
bromelin 12.3
actinidin 11.6
GP-I 11.4
caricain 10.7
streptopain 10.3
RPH 10.3
papain 10.2
chymopapain 9.9
chymopapain 9.8
pyroglutamyl peptidase II 9.4
cathepsin V 8.9
C1 esterase 8.9
clostripain 8.6
cathepsin C 8.3
hydroxylamine oxidoreductase 8.2
acetylesterase 8.2
subtilisin 8.1
cathepsin H 8.0
chymotrypsin 7.9
thermolysin 7.8
glycerophosphate acyltransferase 7.6
pyroglutamate aminopeptidase 7.5
Hageman factor 7.5
cathepsin B 7.1
pepsin 7.1
lysyl endopeptidase 7.0
trypsin 6.9
cathepsin L 6.8
proteinase K 6.6
dipeptidyl peptidase IV 6.5
chitosanase 6.5
kallikrein 6.4
alanine aminopeptidase 6.4
ascorbate oxidase 6.3
neuraminidase 6.2
elastase 6.2
aminopeptidase A 6.2
cruzipain 6.2
lysostaphin 6.0
transpeptidase 6.0
cathepsin S 6.0
PNGase F 5.9
leucine aminopeptidase 5.8
PI-PLC 5.8
cathepsin D 5.7
pectinase 5.7
cathepsin K 5.7
gamma-glutamyl transpeptidase 5.6
carboxypeptidase Y 5.6
acrosin 5.5
SMP 5.5
pectin methylesterase 5.4
acyl-CoA synthetase 5.2
cathepsin G 5.1
Pla 5.1
interstitial collagenase 5.0
BIS 5.0
carboxypeptidase A 5.0
angiotensin-converting enzyme 2 4.9
ECH 4.9
uricase 4.7
arylsulfatase 4.7
acyl-CoA synthetase 4.6
collagenase 4.6
ACE 4.5
hyaluronidase 4.3
polo-like kinase 1 4.3
lipase 4.3
transglutaminase 4.3
beta-glucosidase 4.2
cellulase 4.2
phosphoenolpyruvate carboxylase 4.2
glucose oxidase 4.1
plasmin 4.1
endoglycosidase H 4.1
prostaglandin synthetase 4.1
caspase-9 4.0
more...
Compound
Benzofuroxan 13.7
E 39 13.3
Bromelia 12.4
1,3-dibromoacetone 12.1
PCPI 11.8
Z-Arg-Arg-NHMec 11.0
S-benzylcysteine 10.9
S-benzylcysteine 10.9
S-benzylcysteine 10.5
Sulfamylon 9.7
3-amino-1-propanol 9.4
4-hydroxyphenylarsonic acid 9.3
N-acetylserine 9.1
Gum arabic 8.9
BHA 8.9
E-64 8.9
2-methyl-2-propanol 8.8
2-methyl-2-propanol 8.8
terephthalaldehyde 8.6
Methylsulfonylmethane 8.4
PTMA 8.3
Polybrene 8.1
Z-Gly 8.0
Roxarsone 7.9
3-Methyladenine 7.5
3-hydroxyisovaleric acid 7.5
BTG 7.4
BTG 7.4
Allicin 7.1
Potassium chloride 7.1
BCM 7.1
Phosphorylcholine 7.0
3-methylbutanal 7.0
sulfamic acid 6.9
nonanoic acid 6.8
nonanoic acid 6.8
S-benzyl 6.8
nonanoic acid 6.8
nonanoic acid 6.7
Bacitracin 6.7
Collagenase 6.5
Thioflavin T 6.5
1-pentanol 6.4
DDVP 6.4
2-mercaptoethanol 6.4
ANS 6.4
ANS 6.4
TFE 6.3
Methysergide 6.3
DON 6.3
NH4OH 6.2
HPC 6.2
nonanoic acid 6.1
HPC 6.1
His-Leu 6.1
DBT 6.1
Trypsin 6.1
Cys-Gly 6.0
L-leucine 6.0
phthalaldehyde 6.0
hippurate 5.9
NFS 5.9
methylformamide 5.9
norleucine 5.8
Glu-Glu 5.8
DAP 5.8
DAP 5.8
5-HETE 5.8
Carrageenan 5.7
Factor H 5.7
DPP 5.6
butanal 5.6
MAK 5.6
Kallikrein 5.5
Glucosamine 5.5
hexanoic acid 5.4
oxalacetate 5.4
D-glucosamine 5.4
hexanoic acid 5.4
AFC 5.3
more...