Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.32 (
bromelain
)
1,025
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
chymotrypsin
72
Sep
67
glycoprotein
60
SDS
58
polypeptide
38
neuraminidase
34
lipopolysaccharide
32
cysteine protease
31
Mol
31
cysteine proteinase
29
casein
27
IgE
27
bradykinin
24
collagen
21
LPS
21
HA2
20
cathepsin B
19
Gen
19
cytokine
17
serum albumin
16
lectin
16
TOF
15
NMR
15
CD5
14
peptidase
13
thrombin
13
collagenase
13
cysteine proteinase inhibitor
13
trypsin inhibitor
12
PFC
12
peroxidase
12
HA1
12
lipase
12
lymphoid
11
autoantigen
10
CD44
10
B10
10
Angiotensin-converting enzyme
9
kallikrein
9
amylase
9
gut
9
alkaline phosphatase
9
lysozyme
8
IL-6
8
esterase
8
SRBC
8
heavy chain
7
TNF
7
IFN-gamma
7
membrane-bound
7
cathepsin D
7
IL-4
7
albumin
7
tumor necrosis factor
7
beta 1
7
cathepsin L
7
Trypsin
7
Met
6
IL-5
6
mucin
6
IL-2
6
PEG
6
phospholipase
6
caspase-9
6
brush border
6
gamma-glutamyltransferase
6
angiotensin I-converting enzyme
6
caspase-3
6
gamma-glutamyl transpeptidase
6
CD45
5
spermatozoa
5
PBS
5
cytochrome c
5
Gamma-glutamyl transpeptidase
5
PGA
5
myosin
5
insulin
5
phospholipase A2
5
DBA
5
wts
5
aminopeptidase
4
Bcl-2
4
Pseudomonas
4
fused
4
protease inhibitor
4
placental alkaline phosphatase
4
microsomal
4
CD62L
4
CD4
4
ADP
4
thymus
4
myoglobin
4
transferrin
4
C-terminal peptide
4
p53
4
dimeric
4
VP2
4
Chymotrypsin
4
CD16
4
dilute
4
cathepsin C
4
Thy-1
4
plasma prekallikrein
4
serine protease
4
matrix protein
4
thromboplastin
4
TGF-beta
4
IL-10
4
DPP
4
cytochrome
3
IL-1 beta
3
carp
3
IgA
3
X-linked
3
MUC1
3
Poly
3
antichymotrypsin
3
interleukin-2
3
catalase
3
SOD
3
cathepsin K
3
thyroglobulin
3
TCA
3
gamma-glutamyltranspeptidase
3
chronic renal failure
3
hyaluronidase
3
substance P
3
interleukin-6
3
precursor protein
3
MUC5AC
3
integral membrane protein
3
glucosamine
3
cathepsin H
3
GSH
3
cyclooxygenase-2
3
CD14
3
IL-1
3
TEM
3
28 kDa
3
PLA
3
CPI
3
ACE
3
heat shock protein
3
CCD
3
interferon
3
Hageman factor
3
leucine aminopeptidase
3
phosphatase
3
rheumatoid factor
3
hemoglobin
3
cyclooxygenase
3
prothrombin
3
ribonucleoprotein
3
Fc gamma
3
cryptic
3
glycophorin A
3
elastin
3
dipeptidyl peptidase IV
3
IgG3
3
MRC
3
ATPase
3
ERK2
2
Alkaline phosphatase
2
fibrinogen
2
metallothionein
2
CD2
2
MHC class II
2
COX-2
2
ERK1
2
p38
2
lactoperoxidase
2
hinge
2
carbonic anhydrase
2
L-selectin
2
Fc receptor
2
AMP
2
major histocompatibility complex
2
ESI
2
long chain
2
aspartate aminotransferase
2
IFN
2
A431
2
factor XII
2
chitinase
2
ERK
2
envelope protein
2
amyloid beta
2
osteosarcoma
2
LFA-1
2
interleukin-4
2
rat)
2
MD-2
2
ALA
2
threonine
2
Neuraminidase
2
DAP
2
reductase
2
mast cell
2
extracellular signal-regulated kinase
2
p38 mitogen-activated protein kinase
2
EST
2
DNase
2
antithrombin III
2
urokinase-type plasminogen activator
2
ALP
2
keratin
2
glucosidase
2
SARS
2
lactate dehydrogenase
2
sky
2
fibronectin
2
hepatocyte growth factor
2
surface antigen
2
granulocyte-macrophage colony-stimulating factor
2
calpain
2
unknown function
2
Transglutaminase
2
GABA
2
transglutaminase
2
MHC
2
FIP
2
epidermal growth factor
2
myosin heavy chain
2
TNF-alpha
2
LAK
2
CLA
2
cyclooxygenase 2
2
alpha2-macroglobulin
2
acid phosphatase
2
ferritin
2
trypsinogen
2
cage
2
calcium-activated neutral protease
2
cytochrome P-450
2
thymic stromal lymphopoietin
2
p62
2
CAS
2
CD7
2
chemokine receptor
2
TLR4
2
lymphokine
2
IgH
2
CD8
2
CD62P
2
vimentin
2
MUC2
2
leukocyte interferon
1
MEK
1
CD6
1
alpha-amylase
1
ACR
1
p50
1
DORA
1
EPA
1
P60
1
CCR7
1
SAM
1
THP
1
N-glycanase
1
CD40
1
MRI
1
acetylcholine receptor
1
GALT
1
metalloproteinase
1
placental-like alkaline phosphatase
1
IgL
1
X-linked recessive
1
DPP IV
1
RNase
1
cathepsin G
1
EGFR
1
C6orf62
1
NADPH
1
acetylcholinesterase
1
glutathione peroxidase
1
alpha-1-antichymotrypsin
1
C-C
1
FDC
1
neutral endopeptidase
1
sIL-6R
1
B-CLL
1
RNP
1
CD80
1
BAX
1
scratch
1
lipoxygenase
1
IDA
1
FFM
1
carcinoembryonic antigen
1
sortilin 1
1
VCAM1
1
mouse)
1
interleukin 2
1
metalloprotease
1
IL-33
1
SRM
1
beta-tubulin
1
Interferon-gamma
1
CAP
1
PPD
1
endonuclease G
1
T cell receptor
1
acetyl-CoA carboxylase
1
GP180
1
CD47
1
IL-13
1
MCT
1
Raf-1
1
mitoNEET
1
ATG5
1
MCT1
1
Carboxypeptidase A
1
MMP-2
1
ADC
1
Cathepsin L
1
CCL4
1
interferon gamma
1
eIF5A
1
FEV
1
interferon-gamma
1
more...
Disease
influenza
81
SDS
58
cancer
50
plaque
46
tumor
44
carcinoma
10
breast cancer
9
melanoma
9
hypertension
8
autoimmune disease
8
tumor growth
7
pleurisy
7
systemic lupus erythematosus
6
osteoarthritis
6
bronchitis
6
bronchitis
6
inflammatory bowel disease
6
asthma
5
lymphoma
5
DBA
5
multiple myeloma
5
diabetes
5
cold
5
Spleen
4
hepatocellular carcinoma
4
leukemia
4
lupus
4
proteinuria
4
autoimmune hemolytic anemia
4
rheumatoid arthritis
4
lupus
3
squamous cell carcinoma
3
PAA
3
pseudomyxoma peritonei
3
GSH
3
SARS
3
TEM
3
worms
3
TEM
3
mesothelioma
3
obesity
3
immunodeficiency
3
HIV
3
virus infection
3
MCF
3
chronic renal failure
3
lung cancer
3
rabies
3
CCD
3
cleft palate
3
hemolytic anemia
3
CCD
3
encephalomyelitis
3
tumorigenesis
3
neuropathy
3
B-cell lymphoma
3
antiphospholipid syndrome
3
reticuloendotheliosis
3
infectious diseases
2
avian sarcoma
2
HPC
2
solid tumor
2
mammary tumor
2
malaria
2
dermatitis
2
anemia
2
trismus
2
FIP
2
lymphoproliferative disorders
2
malabsorption
2
cholera
2
adenocarcinoma
2
Nose
2
stomatitis
2
African trypanosomiasis
2
hyperlipidemia
2
Plaque
2
multiple sclerosis
2
Placenta
2
ischemia
2
pruritus
2
endometriosis
2
Newcastle disease
2
osteosarcoma
2
arthritis
2
pancreatic cancer
2
ulcerative colitis
2
colitis
2
Brown
2
cirrhosis
2
colorectal cancer
2
metastases
2
uterus
2
Glanzmann's thrombasthenia
2
lymphocytic choriomeningitis
2
allergic rhinitis
2
SCID
2
sinusitis
2
thrombophlebitis
2
chronic sinusitis
2
FIP
2
Barrett's esophagus
1
rind
1
glioma
1
MRS
1
FA2
1
depression
1
Alzheimer's disease
1
polio
1
polycystic ovary syndrome
1
IVF
1
FDC
1
ICP
1
Crohn's disease
1
intussusception
1
VPI
1
Goldblatt hypertension
1
calcinosis
1
AAA
1
dyskinesia
1
sepsis
1
mole
1
Osteosarcoma
1
USH2A
1
glioblastoma multiforme
1
vaccinia
1
Irritant contact dermatitis
1
cutaneous melanoma
1
PSS
1
Blocking
1
Osteosarcoma
1
peptic ulcer
1
abdominal aortic aneurysm
1
Colitis
1
nephrosclerosis
1
Thymus
1
arthropathy
1
Echinococcus
1
lung carcinoma
1
hypergammaglobulinemia
1
Atopic
1
hay fever
1
scleroderma
1
protein deficiency
1
Contact Dermatitis
1
renal disease
1
AGS
1
THC
1
Pancreas
1
chronic obstructive pulmonary disease
1
PCL
1
mole
1
dehydration
1
HPP
1
residual disease
1
sarcoma
1
papillary thyroid cancer
1
sepsis
1
xerostomia
1
SLE
1
GALT
1
type 2 diabetes
1
Mycobacterium
1
lactose intolerance
1
gastric cancer
1
psychosis
1
malnutrition
1
Proteinuria
1
type 1 diabetes
1
mental illness
1
rheumatism
1
Still
1
prostate cancer
1
diabetic nephropathy
1
gastrointestinal cancer
1
ichthyosis
1
Cryptococcus neoformans
1
tumor progression
1
Frey
1
chronic bronchitis
1
synovitis
1
gastritis
1
fits
1
gastroenteritis
1
ash
1
Epstein
1
Lequesne
1
CAP
1
RP19
1
arteriosclerosis
1
enteritis
1
cryptosporidiosis
1
lupus nephritis
1
syphilis
1
digestive system cancer
1
Cholangiocarcinoma
1
Appendix
1
Appendix
1
liver cancer
1
B-cell lymphomas
1
Schmitz
1
ED3
1
anaphylaxis
1
Arthus reaction
1
hepatitis
1
peripheral neuropathy
1
mastitis
1
hepatitis A
1
plasmacytoma
1
hepatitis B
1
abortion
1
pyelonephritis
1
PAF
1
EL4
1
ileus
1
portal hypertension
1
Hereditary angioedema
1
mucinous carcinoma
1
retinoblastoma
1
Parkinson's disease
1
Thymus
1
Infection
1
roundworm
1
Rous sarcoma
1
tetanus
1
CAM
1
urticaria
1
Appendix
1
chronic fatigue syndrome
1
cervical intraepithelial neoplasia
1
Clostridium difficile colitis
1
monocytic leukemia
1
parvovirus
1
infertility
1
rhinitis
1
Hymenolepis
1
Pancreas
1
renal insufficiency
1
rare disease
1
Cholangiocarcinoma
1
food allergy
1
pancreatic insufficiency
1
COPD
1
BCM
1
alcoholic fatty liver
1
babesiosis
1
photosensitivity
1
renal failure
1
acute myeloid leukemia
1
renal cancer
1
papilloma
1
colibacillosis
1
carcinogenesis
1
Perennial allergic rhinitis
1
threatened abortion
1
Thymus
1
lung metastases
1
Symptom
pain
23
diarrhea
5
fatigue
3
angina
2
acidity
2
agitation
2
bitter taste
2
discomfort
1
abdominal pain
1
anesthesia
1
autodigestion
1
exhaustion
1
nausea
1
sneezing
1
thinning
1
Tenderness
1
knee pain
1
erythema
1
joint stiffness
1
low back pain
1
infant diarrhea
1
nasal discharge
1
stigma
1
rhinorrhea
1
discomfort
1
analgesia
1
memory loss
1
nasal congestion
1
numbness
1
persistent cough
1
Drug
Bromelain
125
Papain
17
lysine
14
Asn
13
ascorbate
9
Pronase
6
IFN-gamma
6
IL-2
6
vitamin E
6
Dermatol
5
lactose
4
Gelatin
4
Gel
4
MRC
3
Protein hydrolysate
3
Fraction
3
CaCl2
2
CAM
2
Leaf
2
Kaolin
2
CaCl2
2
CaCl2
2
Biopolymers
2
AMC
2
Captopril
2
RPH
2
caffeine
2
Ethanol
2
Forskolin
1
L-tyrosine
1
citric acid
1
Pancrease
1
Lactose
1
EPA
1
Vitamin A
1
Etodolac
1
Dial
1
Urokinase
1
NADH
1
Trifluoroethanol
1
Ginger
1
Guanidine
1
Alanine
1
Guanidine
1
Travase
1
CTC
1
CTA
1
uPA
1
MAP
1
Tocopherol
1
Aprotinin
1
PTC
1
nitroglycerin
1
ROS
1
Lysostaphin
1
Aloe
1
Dodecyl Sulfate
1
Sulfamylon
1
3-Methyladenine
1
Vitamin E
1
FAD
1
ampicillin
1
CTC
1
CFS
1
Enzyme
bromelain
1025
papain
251
trypsin
157
stem bromelain
101
ficin
93
chymotrypsin
84
subtilisin
39
pepsin
37
neuraminidase
35
elastase
22
cathepsin B
19
bromelin
18
kallikrein
17
peroxidase
14
actinidin
14
collagenase
14
gamma-glutamyl transpeptidase
14
thermolysin
14
proteinase K
13
ACE
13
chymopapain
13
thrombin
13
lipase
12
chymopapain
12
alkaline phosphatase
9
lysozyme
8
phospholipase C
7
cathepsin D
7
cathepsin L
7
thromboplastin
6
mitogen-activated protein kinase
6
GP-I
5
plasmin
5
phospholipase A2
5
CD10
5
dipeptidyl peptidase IV
5
ERK
4
cellulase
4
caspase-9
4
caspase-3
4
cathepsin C
4
pectinase
4
catalase
4
lactate dehydrogenase
3
ATPase
3
cathepsin H
3
urease
3
transpeptidase
3
caricain
3
glucose oxidase
3
protein kinase
3
clostripain
3
hyaluronidase
3
hyaluronidase
3
transglutaminase
3
urease
3
PNGase F
3
Hageman factor
3
leucine aminopeptidase
3
cathepsin K
3
superoxide dismutase
3
alpha-amylase
2
beta-glucosidase
2
carboxypeptidase Y
2
alanine aminotransferase
2
acid phosphatase
2
lysyl endopeptidase
2
invertase
2
focal adhesion kinase
2
deaminase
2
carbonic anhydrase
2
proteasome
2
CPR
2
reverse transcriptase
2
chitinase
2
ascorbate oxidase
2
glycerophosphate acyltransferase
2
acetylesterase
2
RPH
2
cathepsin G
2
aspartate aminotransferase
2
DNase
2
alanine aminopeptidase
2
phosphoenolpyruvate carboxykinase
1
hexosaminidase
1
CD13
1
lipoxygenase
1
acrosin
1
BIS
1
aminopeptidase A
1
AMP-activated protein kinase
1
streptopain
1
chitosanase
1
interstitial collagenase
1
alpha-glucosidase
1
neutrophil elastase
1
adenylate cyclase
1
luciferase
1
lysostaphin
1
cathepsin S
1
acetyl-CoA carboxylase
1
demethylase
1
acyl-CoA synthetase
1
C1 esterase
1
caspase-8
1
beta-galactosidase
1
MEK
1
pyruvate kinase
1
ECH
1
SMP
1
carboxypeptidase A
1
pectin methylesterase
1
tryptase
1
phosphorylase
1
acyl-CoA synthetase
1
creatine kinase
1
angiotensin-converting enzyme 2
1
beta-glucuronidase
1
Pla
1
cruzipain
1
RNase
1
APC
1
MAP
1
hydroxylamine oxidoreductase
1
urokinase-type plasminogen activator
1
AMPK
1
lipoprotein lipase
1
prostate-specific antigen
1
PI-PLC
1
glutaminase
1
endoglycosidase H
1
glutathione S-transferase
1
protein kinase C
1
RNase
1
ricin
1
cathepsin V
1
tyrosinase
1
pyroglutamate aminopeptidase
1
sialidase
1
MDP
1
uricase
1
polo-like kinase 1
1
sulfatase
1
pyroglutamyl peptidase II
1
cdc2
1
PARP
1
ACS
1
phosphoenolpyruvate carboxylase
1
phosphoenolpyruvate carboxykinase
1
acetylcholinesterase
1
arylsulfatase
1
phosphoenolpyruvate carboxykinase
1
sucrase
1
caspase-1
1
renin
1
glutathione peroxidase
1
prostaglandin synthetase
1
AMPK
1
cholinesterase
1
Compound
cysteine
97
Dec
87
water
61
sodium
59
SDS
58
DNA
43
Clin
36
serine
36
sulfate
32
ammonium
28
alanine
27
arginine
27
Phe
26
lysine
22
tryptophan
21
tryptophan
21
leucine
20
tryptophan
19
tryptophan
19
acetone
19
tyrosine
18
Gly
18
oxygen
18
His
17
methionine
16
acrylamide
16
urea
15
GlcNAc
15
TOF
15
phosphate
15
E-64
14
PEG
14
hydrogen
14
DEAE
13
Asp
13
bromide
12
glucose
11
2-mercaptoethanol
11
ethanol
11
xylose
11
galactose
11
zinc
11
calcium
11
salt
10
naphthalene
10
DPPH
10
TCA
10
glutamate
10
BHA
10
glutamine
9
Ile
9
ANS
9
copper
9
ANS
9
acetate
9
NH2
8
Bromelia
8
PEG
8
N-acetylcysteine
8
asparagine
8
proline
8
glutamic acid
8
EDTA
7
Trypsin
7
Triton X-100
7
EDTA
7
guanidine
7
TNF
7
nitrogen
7
DBA
6
threonine
6
iron
6
PGE2
5
potassium
5
aspartic acid
5
L-leucine
5
nitric oxide
5
DBA
5
iodine
5
Pac
5
aspartic acid
5
aspartic acid
5
DBA
5
aspartic acid
5
methanol
5
glycerol
5
benzaldehyde
4
valine
4
ADP
4
hexose
4
MTT
4
vitamin D
4
DPP
4
phenol
4
PAM
4
ADP
4
N-isopropylacrylamide
4
MDA
4
ADP
4
PMA
4
PAM
4
Cysteine
4
acrylic acid
4
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
Collagenase
3
benzaldehyde
3
benzaldehyde
3
Optimal
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
aldehyde
3
sodium chloride
3
pyrene
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
octane
3
Triton
3
5-FU
3
TEM
3
benzaldehyde
3
benzaldehyde
3
PAA
3
benzaldehyde
3
benzaldehyde
3
diacetate
3
Benzofuroxan
3
benzaldehyde
3
Phosphatidylinositol
3
MIA
3
benzaldehyde
3
selenium
3
PMA
3
GSH
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
benzaldehyde
3
silver
3
TFE
3
benzaldehyde
3
GSH
3
benzaldehyde
3
benzaldehyde
3
creatinine
3
benzaldehyde
3
ammonia
3
Chitosan
2
Bradykinin
2
AMP
2
D-glucosamine
2
Tris
2
prostaglandin E1
2
GABA
2
2-ethylhexyl
2
GMP
2
Thioflavin T
2
Sodium
2
Congo red
2
2-ethylhexyl
2
cyclohexanone
2
CaCl2
2
ALP
2
betaine
2
ornithine
2
GABA
2
DON
2
DAP
2
ornithine
2
ornithine
2
ornithine
2
coenzyme Q10
2
chloroform
2
PGE
2
ethyl acetate
2
Tris
2
Dextran
2
hyaluronic acid
2
DMF
2
L-carnitine
2
hexose
2
palmitic acid
2
ornithine
2
aldehyde
2
hexose
2
2-ethylhexyl
2
CTAB
2
hippurate
2
phthalaldehyde
2
Salt
2
HCl
2
isoleucine
2
norleucine
2
palmitic acid
2
hexose
2
prostacyclin
2
DDVP
2
hydroxide
2
HPC
2
acetic acid
2
HPC
2
Ascorbic acid
2
caffeine
2
isoleucine
2
COS
2
Polybrene
2
Diazepam
2
CAM
2
DAP
2
MBC
2
Casein
2
gallic acid
2
DPA
1
NADH
1
2-oxoglutarate
1
phosphite
1
DHA
1
NADPH
1
hexadecyl
1
NADP
1
Neu5Ac
1
stearic acid
1
naphthoquinone
1
pyrimidine
1
DDP
1
EPA
1
BCM
1
methylformamide
1
NH4OH
1
TCM
1
UDP-galactose
1
MIC
1
Potassium chloride
1
S-benzylcysteine
1
2-hydroxyethyl
1
2-methyl-2-propanol
1
Glucosamine
1
MEK
1
GalNAc
1
BTG
1
PGD2
1
ADR
1
AAA
1
SPF
1
MAK
1
1,8-cineole
1
Mannose
1
PCPI
1
oxalacetate
1
Dial
1
Tyrosine
1
Forskolin
1
octyl
1
acetonitrile
1
dimethylarsinic acid
1
PPO
1
DPA
1
E 39
1
MCP
1
oxalate
1
2-hydroxyethyl
1
butanal
1
CAT
1
1,3-dibromoacetone
1
Fibrin
1
MBC
1
aluminum
1
CAT
1
dimethylarsinic acid
1
vinyl
1
decyl
1
Methysergide
1
hydrazine
1
3-methylbutanal
1
naphthoquinone
1
dihydrogen phosphate
1
nonanoic acid
1
Glutaraldehyde
1
NADPH
1
pyridine
1
nonanoic acid
1
1-propanol
1
THP
1
FAD
1
FMN
1
Cyt
1
sulfamic acid
1
dimethylarsinic acid
1
Kallikrein
1
1-butanol
1
S-benzylcysteine
1
cyanamide
1
Phosphorylcholine
1
Trehalose
1
1-pentanol
1
3-amino-1-propanol
1
MAP
1
2-hydroxyethyl
1
Z-Arg-Arg-NHMec
1
methane
1
DBT
1
TRH
1
2-hydroxyethyl
1
Curcumin
1
Cellulose
1
DMSO
1
DBP
1
hexane
1
naphthoquinone
1
2-methyl-2-propanol
1
PGH2
1
dimethylarsinic acid
1
more...