Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.22.32 (
bromelain
)
1,025
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
5he effect of age on the immunological responses to Babesia microti infection in the mouse was investigated. Aged mice experienced reduced and delayed peak parasitemias compared to younger animals; however, the old mice failed to clear the parasites from the blood and experienced fluctuating parasitemias until death.
Babesiosis
produced suppression of responses to nonspecific B and T cell mitogens concomitant with rising autoantibody plaque forming cells reactive with untreated and
bromelain
modified mouse erythrocytes. Similar observations of increased susceptibility to
babesiosis
with age and immunosuppression have been made in human
babesiosis
. Thus, the murine model for this hemoprotozoan infection is faithful to the human immunological responses.
...
PMID:The effect of age on the infection and immunoresponsiveness of mice to Babesia microti. 665 19
