Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.22.25 (chymopapain)
 430 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
STK-1 12.2
CD34 molecule 11.4
HPCA 11.0
cystatin D 10.6
cysteine proteinase 9.6
cathepsin H 9.6
cysteine proteinase inhibitor 9.5
CD19 antigen 9.5
GSH2 9.5
Chondroitinase 9.4
cysteine endopeptidase 9.4
CD34 antigen 9.4
CEI 9.4
P68 9.3
N-acetylmuramoyl-L-alanine amidase 9.3
chondroitinase 8.9
cathepsin S 8.7
SCC antigen 8.6
cartilage-derived 8.6
CD51 8.5
artemin 8.3
cathepsin L 8.2
elastase inhibitor 8.0
Cathepsin L 7.8
prolyl endopeptidase 7.7
cathepsin C 7.6
flt 7.6
SIP 7.4
CPB 7.4
Hyaluronidase 7.4
alanyl 7.2
cathepsin B 7.1
SUP 7.1
cysteine protease 7.0
TSK 7.0
cytokeratin 8 6.9
CPI 6.9
proteoglycan 6.9
PME 6.8
Chymotrypsin 6.8
ABC 6.8
collagenase 6.8
prolidase 6.8
serine proteinase inhibitor 6.7
FAST 6.7
MK2 6.6
cystatin C 6.4
cathepsin G 6.3
P16 6.1
EMD 6.0
PPP 6.0
Thy-1 5.9
epithelial cell adhesion molecule 5.9
Proteinase 5.9
N-myc 5.7
chymotrypsin 5.7
p17 5.7
IgE 5.6
cathepsin D 5.6
cyclophilin 5.6
C11 5.5
chymotrypsin-like 5.4
aggrecan 5.3
CD34 5.3
cathepsin K 5.3
calpain 5.2
syndecan 5.2
deoxyribonuclease 5.1
chitinase 5.1
PGD2 5.1
CD33 5.1
galactosamine 5.0
CD13 5.0
hyaluronidase 5.0
MSC 5.0
Calcitonin 5.0
CD38 5.0
CD62L 4.9
L-selectin 4.9
trypsin inhibitor 4.9
more...
Disease
discitis 10.6
herniated disc 10.4
psychasthenia 9.8
Lumbar disc herniation 9.7
encephalomyelopathy 9.5
Oppenheim 9.4
psychogenic pain 9.3
spinal stenosis 8.6
arachnoiditis 8.5
nerve root compression 8.3
metastatic neuroblastoma 8.1
anaphylaxis 8.1
spondylosis 7.8
metastatic neuroblastoma 7.8
hypochondriasis 7.8
cauda equina syndrome 7.7
hysteria 7.7
disc degeneration 7.6
hypomania 7.6
Lowe 7.5
Heymann nephritis 7.4
vascular obstruction 7.0
spondylolisthesis 6.9
radiculopathy 6.9
paranoia 6.8
serum sickness 6.8
allergic conjunctivitis 6.6
mononeuropathy 6.6
meninges 6.4
epithelioma 6.3
osteochondrosis 6.3
degenerative disc disease 6.2
myelitis 5.9
drug hypersensitivity 5.9
osteoporotic fracture 5.8
spondylitis 5.8
rhinitis 5.7
infectious endocarditis 5.7
EMD 5.7
paraplegia 5.6
childhood asthma 5.4
OCD 5.3
neurofibroma 5.2
urticaria 5.1
hernia 5.0
thrombophlebitis 4.9
uterine leiomyoma 4.8
Barrett's esophagus 4.8
EIA 4.7
degenerative disease 4.7
African trypanosomiasis 4.7
PDB 4.5
diabetic neuropathy 4.4
pruritus 4.3
lymphoblastic leukemia 4.3
follicular lymphoma 4.2
food allergy 4.2
chondrosarcoma 4.1
conjunctivitis 3.9
decubitus 3.8
respiratory disease 3.7
subarachnoid hemorrhage 3.7
mole 3.6
ankylosing spondylitis 3.5
mole 3.4
bone disease 3.3
allergic rhinitis 3.2
Proteus 3.2
hematologic malignancies 3.2
scoliosis 3.1
chronic myeloid leukemia 3.0
cleft palate 2.8
neuropathy 2.7
prolapse 2.7
osteoarthritis 2.6
multiple myeloma 2.6
Evans 2.6
tetanus 2.6
celiac disease 2.5
non-Hodgkin's lymphoma 2.4
more...
Symptom
sciatica 10.8
Radicular pain 10.7
Neurologic symptoms 8.7
leg pain 8.6
abdominal cramps 7.1
back pain 6.9
low back pain 6.8
chronic back pain 6.6
chest tightness 6.6
dysesthesia 6.3
spasm 6.1
tingling 5.9
Sedation 5.8
neuralgia 5.4
sneezing 5.3
rhinorrhea 5.0
wheezing 5.0
paresthesia 4.9
shortness of breath 3.8
anesthesia 3.8
pain 3.4
nausea and vomiting 2.9
discomfort 2.7
discomfort 2.6
erythema 2.5
collapse 2.4
acidity 2.3
chest pain 2.1
weakness 2.0
respiratory distress 1.9
analgesia 1.4
headache 0.4
diarrhea 0.4
Drug
Chymopapain 15.7
Conray 9.7
Kaolin 8.3
Papain 8.0
anti-CD33 7.8
Pronase 7.4
Hyaluronidase 7.4
Hyaluronidase 7.2
Metrizamide 7.0
ABC 6.8
Bupivacaine 6.6
Hypaque 6.1
Hypaque 5.9
MgSO4 5.6
L-tyrosine 5.0
Histamine 4.7
G-CSF 3.8
Asn 3.7
Gel 2.3
Leaf 1.8
Asthma 1.5
lysine 0.3
Enzyme
chymopapain 16.2
chymopapain 16.2
chondroitin sulfate ABC endolyase 15.2
caricain 15.0
EC 6.3.1.8 13.6
stem bromelain 12.2
streptopain 11.6
actinidin 11.3
ficin 11.2
bromelin 10.4
GP-I 10.3
glycoprotease 10.2
C1 esterase 10.1
bromelain 9.9
papain 9.7
proteinase A 9.7
cathepsin H 9.7
alpha-lytic protease 9.4
clostripain 9.2
proteinase A 9.1
cathepsin S 8.8
chondroitinase 8.8
chondroitinase 8.7
endoproteinase Glu-C 8.5
cathepsin L 8.2
endo-beta-galactosidase 8.2
murein hydrolase 7.9
cathepsin C 7.6
hyaluronidase 7.3
prolidase 7.2
cathepsin B 7.2
beta-1,3-glucanase 6.8
beta-1,3-glucanase 6.8
deaminase 6.7
FAST 6.6
prolyl endopeptidase 6.5
PRA 6.5
subtilisin 6.4
cathepsin G 6.4
collagenase 6.3
thermolysin 6.3
carboxypeptidase A 6.2
chymotrypsin 5.9
rubisco 5.8
cathepsin D 5.7
deoxyribonuclease 5.7
elastase 5.6
deoxyribonuclease 5.6
pepsin 5.4
cathepsin K 5.3
proteinase K 5.2
chitinase 5.1
MDR 5.1
hyaluronidase 5.0
trypsin 5.0
BMT 4.8
tryptase 4.7
CD13 4.4
CD10 3.9
glutamine synthetase 3.9
phosphorylase 3.7
kallikrein 3.6
phospholipase A2 3.4
neuraminidase 3.4
DNase 3.3
lysozyme 2.8
acid phosphatase 2.5
reverse transcriptase 2.2
APC 2.2
DNA polymerase 2.1
ACE 2.0
phospholipase C 2.0
catalase 0.4
superoxide dismutase 0.3
peroxidase 0.2
Compound
PCPI 13.0
N-acetylphenylalanine 11.1
N-acetylphenylalanine 11.1
Deoxypyridinoline 9.7
E-64 8.9
keratan sulfate 8.7
Terfenadine 8.2
hexuronic acid 8.1
hexuronic acid 8.1
hexuronic acid 8.1
hexuronic acid 8.1
Nitrofurantoin 8.0
Safranin O 7.9
PHE 7.5
CPB 7.5
Cortisone 7.3
Bupivacaine 6.6
Chondroitin sulfate 6.5
Paraquat 6.2
Paraquat 6.1
Cysteine 6.0
Hypaque 5.8
cysteine 5.8
PMSF 5.7
nitrous acid 5.3
PGD2 5.3
MBC 5.1
Calcitonin 5.0
MBC 5.0
MDR 4.9
Histamine 4.7
LTC4 4.7
Trypsin 4.5
glutamic acid 4.5
PDB 4.3
Gly 4.1
hexose 4.1
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
2-hydroxyethyl 4.0
Morphine 3.8
APAP 3.8
serine 3.8
2-hydroxyethyl 3.7
hexose 3.6
hexose 3.6
hexose 3.6
GalNAc 3.5
6-12 3.4
DEAE 3.3
DMSO 3.2
aniline 3.1
acrylamide 3.1
DMF 3.1
alanine 3.1
EDTA 3.0
EDTA 3.0
Tris 3.0
CAT 3.0
CAT 3.0
guanidine 3.0
molybdenum 3.0
CAT 2.9
Panam 2.9
isoleucine 2.9
Tris 2.8
isoleucine 2.8
arginine 2.8
bromide 2.8
N-acetylcysteine 2.8
His 2.7
sulfate 2.7
naphthalene 2.7
asparagine 2.6
hyaluronic acid 2.6
Phe 2.5
more...