Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.9 (enterokinase)
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Human Gene/Protein
enterokinase 15.5
enteropeptidase 15.5
YSA1H 14.5
Serase-1B 14.5
epitheliasin 14.5
Epitheliasin 14.5
mesotrypsinogen 14.1
HLAL 13.5
spinesin 13.5
hemochromatosis type 2 13.5
DESC1 13.2
trypsinogen 4 12.9
anionic trypsinogen 12.7
PHAP I 12.5
25KD 12.4
YSA1 12.4
TMPRSS9 12.4
trypsinogen 12.3
trypsin 1 12.1
Acid carboxypeptidase 12.1
mesotrypsin 11.9
frizzled 1 11.8
serine protease 1 11.5
PBII 11.4
GPR116 11.4
airway trypsin-like protease 11.4
corin 11.3
cationic trypsinogen 11.3
Pyrroline-5-carboxylate reductase 10.9
Complement receptor type 1 10.9
aldehyde oxidase 1 10.8
PRSS3 10.8
sperm protein 10.8
ALT2 10.7
insulinoma-associated protein 2 10.7
PTPRR 10.7
sentrin-specific protease 10.6
GRM6 10.6
MAT2 10.6
PRSS2 10.6
C4.4A 10.5
Trx 10.5
beta-tubulin protein 10.4
GPR126 10.3
HFE2 10.3
hepsin 10.3
BD6 10.3
Hexokinase-2 10.2
agrin 10.2
HD-6 10.2
collectrin 10.1
neurotrypsin 10.1
Nucleoporin 10.1
Interleukin-24 10.0
Corin 9.9
MT-SP1 9.9
TMPRSS4 9.9
O-sialoglycoprotein endopeptidase 9.8
TMPRSS3 9.7
PRSS1 9.7
single chain Fv fragment 9.7
LPA5 9.6
collagen-like protein 9.6
maltase-glucoamylase 9.4
OG2 9.4
beta-tryptase 9.4
DB5 9.3
ferroportin1 9.3
FHL-1 9.2
PAP2 9.2
fibrocystin 9.2
pancreatic secretory trypsin inhibitor 9.1
CD30 ligand 9.0
hemoglobin beta 9.0
trypsin-like serine protease 9.0
KIAA0319 9.0
ADAM8 9.0
Smad anchor for receptor activation 8.9
BDH 8.9
type II integral membrane protein 8.9
more...
Disease
Intestinal enterokinase deficiency 15.5
Edematous pancreatitis 10.7
HFE2 9.4
glucose-galactose malabsorption 9.1
Acute necrotizing pancreatitis 9.0
HEP 8.6
chronic enteritis 8.0
alcoholic pancreatitis 7.6
pancreatic insufficiency 7.5
Tag 7.4
acrodermatitis enteropathica 7.1
Crabs 7.0
duodenitis 6.9
RPC 6.9
acute pancreatitis 6.7
western equine encephalomyelitis 6.5
trichuriasis 6.5
juvenile myelomonocytic leukemia 6.4
pancreatitis 6.4
steatorrhea 6.3
failure to thrive 6.1
lactose intolerance 6.0
MCS 6.0
MCS 6.0
monocytic leukemia 6.0
Lymph nodes 5.8
erythropoietic protoporphyria 5.8
HPC 5.6
chronic pancreatitis 5.5
protein deficiency 5.5
carcinoma of the pancreas 5.4
Pancreas 5.3
CCL 5.2
chronic myelomonocytic leukemia 5.1
Pancreas 5.1
malabsorption 5.0
SDS 5.0
Wells 4.9
EDC 4.8
Luminal 4.7
iron deficiency anemia 4.6
erythroleukemia 4.5
Schistosoma japonicum 4.4
Osteosarcoma 4.4
Osteosarcoma 4.4
enteropathy 4.4
ADH 4.4
biliary obstruction 4.3
HPA 4.1
EIA 4.1
listeriosis 4.0
PGA 3.9
seminal vesicles 3.8
Schistosoma mansoni 3.7
insulinoma 3.7
fibrosarcoma 3.7
Cryptococcus neoformans 3.5
celiac disease 3.4
Disorder 3.3
ICP 3.2
SCH 3.2
dyskinesia 3.2
adult respiratory distress syndrome 3.1
liver cancer 3.0
Adhesion 3.0
CTX 3.0
cystic fibrosis 2.9
bronchitis 2.9
bronchitis 2.8
Legionella 2.8
malnutrition 2.7
diphtheria 2.7
liver cancer 2.6
epididymis 2.5
peptic ulcer 2.5
Mycobacterium 2.4
schistosomiasis 2.4
gastric cancer 2.4
urethra 2.3
APC 2.2
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Symptom
autodigestion 8.2
hypoproteinemia 7.4
HSA 4.0
diarrhea 3.2
tremor 2.4
constipation 2.2
acidity 1.6
respiratory distress 1.3
abdominal pain 0.6
vomiting 0.6
pain -0.9
Drug
Sodium carbonate 9.8
Neocarzinostatin 8.8
Salmon calcitonin 8.0
Secretin 7.6
GNA 7.4
Lactase 7.4
Aprotinin 7.3
Dexon 7.2
AMC 6.9
KGF 6.6
Papain 6.4
Doxycycline 5.4
IL-11 5.4
TAT 5.3
CCL 5.2
Ranitidine 4.9
uPA 4.5
Fragment 4.3
Asn 4.3
lysine 4.3
L-tyrosine 4.3
ETA 4.1
Alanine 4.1
Gel 4.0
IFN-beta 4.0
Glucagon 3.7
DNase I 3.5
lactose 3.5
Biopolymers 3.5
CTX 3.1
CTX 3.0
CaCl2 2.9
CaCl2 2.9
CaCl2 2.8
EPA 2.7
Nephron 2.4
Ethanol 2.3
CTX 2.2
NADH 2.1
Dial 1.6
ampicillin 1.5
IL-2 0.7
Dermatol -2.5
Enzyme
enterokinase 15.5
mast cell protease 5 13.5
ADP-sugar pyrophosphatase 12.9
duodenase 12.9
oxidized PVA hydrolase 12.7
PVA dehydrogenase 12.2
yeast ubiquitin hydrolase 12.1
deuterolysin 11.0
neurosin 10.5
hepsin 10.3
hepsin 10.3
carboxyl proteinase 10.3
fibrolase 10.1
cyclomaltodextrinase 9.7
plasmepsin II 9.1
sucrase 8.7
matriptase 8.6
glycoprotease 8.6
sucrase-isomaltase 8.6
matriptase 8.6
tripeptidyl peptidase 8.4
jararhagin 8.2
3C protease 8.2
lactase 8.2
carboxypeptidase G2 8.0
mannosidase I 7.8
TDH 7.7
trehalase 7.7
histidase 7.7
trypsin 7.6
carboxypeptidase A 7.6
invertase 7.6
alpha-glucosidase 7.5
chymase 7.5
leucine aminopeptidase 7.4
meprin 7.4
HPI 7.3
disulfide reductase 7.1
acrosin 7.1
chymotrypsin 7.1
chitosanase 7.1
anthranilate synthase 7.1
guanylate kinase 7.0
alanine aminopeptidase 7.0
alcohol oxidase 7.0
dextranase 6.9
aminopeptidase A 6.8
endoproteinase Glu-C 6.8
chorismate mutase 6.7
lactic acid dehydrogenase 6.7
lactic acid dehydrogenase 6.6
lysostaphin 6.6
lysin 6.5
tryptase 6.4
PI-PLC 6.4
cathepsin B 6.3
cathepsin G 6.3
carboxypeptidase B 6.3
elastase 6.1
phenylalanine hydroxylase 6.1
glucoamylase 6.1
MCS 5.9
prolyl endopeptidase 5.9
plasmin 5.8
dipeptidyl peptidase IV 5.8
TSP-1 5.8
12-lipoxygenase 5.8
subtilisin 5.7
beta-secretase 5.7
MDP 5.7
ALDH 5.7
Pla 5.7
glutathione S-transferase 5.6
thromboplastin 5.5
alpha-amylase 5.5
pepsin 5.5
proprotein convertase 5.4
granzyme B 5.4
lipase 5.3
N-acetyltransferase 5.3
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Compound
6-Methyluracil 12.4
Hexamethyldisiloxane 11.8
Diphenoxylate 11.7
Prephenate 10.0
Diisopropyl fluorophosphate 9.4
Benzamidine 9.4
Ectoine 9.1
NTA 9.1
BDH 8.8
Neocarzinostatin 8.8
HEP 8.6
Chloramine-T 8.6
Heptachlor 8.0
MUA 8.0
TNB 7.9
Thioredoxin 7.6
Trypsin 7.6
Secretin 7.5
ADP-glucose 7.5
Glu-Glu 7.4
DMB 7.4
DEX 7.3
BEP 7.3
E-64 7.2
DMB 7.1
Gliotoxin 7.0
IDA 6.9
Pentagastrin 6.9
carbonic acid 6.7
DTP 6.7
Factor X 6.6
Coomassie Blue 6.6
Melittin 6.5
carbonic acid 6.5
3-hydroxybutyric acid 6.4
CHAPS 6.3
Neomycin 6.2
Nordihydroguaiaretic acid 6.2
Asp 6.1
Histidine 6.0
His 6.0
DPC 5.9
DPC 5.9
TAP 5.8
nickel 5.8
HIS 5.8
MAL 5.7
Elastin 5.7
Agar 5.5
GAP 5.5
Doxycycline 5.5
DEAE 5.5
Hydroxyproline 5.4
lysine 5.4
serine 5.3
Heparan sulfate 5.3
PMSF 5.1
Thrombin 5.0
Thyroxine 5.0
DPPC 4.9
Gly 4.9
SDS 4.9
DPPC 4.9
PLP 4.8
Phosphatidylcholine 4.8
SOA 4.8
Serine 4.8
EDC 4.7
LPC 4.7
ANCA 4.7
D-Ala 4.6
aspartic acid 4.6
Cytochrome c 4.6
PMA 4.5
aspartic acid 4.5
Ile 4.5
aspartic acid 4.5
COS 4.5
Triton 4.5
arginine 4.4
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