Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.79 (granzyme B)
 3,301 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CMH1 13.2
Minor histocompatibility antigen HA-1 13.2
CTLA1 13.2
granzyme B variant 13.2
granzyme H 13.2
granzyme B 13.0
proteinase inhibitor 9 12.4
cytotoxic granule-associated RNA-binding protein 12.2
ELKL motif kinase 12.2
EH-binding protein 11.7
cPOP2 11.7
granzyme A 11.5
CGL-2 11.5
Granzyme K 11.4
glutamate receptor subunit 3 11.2
TCRgamma alternate reading frame protein 11.2
TIA-1 11.1
CMH-1 11.1
perforin 11.0
G protein-coupled receptor 83 10.9
SECT 10.8
PTAG 10.7
ADAM 23 10.7
SERP2 10.7
KCTD9 10.7
granulysin 10.5
proteinase inhibitor 8 10.4
EAT2 10.4
RAH 10.4
ZNF683 10.4
ROR-alpha 10.4
CCDC134 10.4
wingless-type MMTV integration site family, member 5A 10.4
gamma2-adaptin 10.4
IL-15RA 10.4
GNLY 10.4
granzyme K 10.4
TIA1 10.3
TRAJ33 10.2
GZMH 10.2
CD107a 10.1
PFP 10.1
PN-I 10.1
retinoic acid early transcript 1 10.1
NKP46 10.1
Osteoclast-associated receptor 10.1
p42.3 10.1
plexin B2 10.1
DCN protein 10.1
ccp1 9.9
Tyrosinase-related protein-2 9.9
Serine proteinase inhibitor 9.9
eomesodermin 9.8
ICH-2 9.8
carboxypeptidase A4 9.8
GALNT10 9.8
KLRG1 9.7
CAP3 9.7
FAIM3 9.7
PAGE4 9.7
killer-cell Ig-like receptor 9.7
SAM50 9.7
HLA-DRB1*0402 9.7
TRBV13 9.7
Dual-specificity phosphatase 2 9.7
ITSN 9.7
UFD2 9.7
MET1 9.5
serglycin 9.5
CD8 beta chain 9.4
carboxypeptidase A3 9.4
TN14 9.4
Granulysin 9.4
IL13RA1 9.3
ACRBP 9.2
ccr6 9.2
Br140 9.2
natural killer cell stimulatory factor 9.2
NKL 9.2
SLAMF4 9.1
more...
Disease
CMH1 13.2
B16 Melanoma 11.2
Pneumonic tularemia 10.9
RCMD-RS 10.7
Lobular panniculitis 10.2
T/NK-cell lymphoma 9.7
AGEP 9.1
Enteropathy-associated T-cell lymphoma 8.9
Infective dermatitis 8.8
Cutaneous Lymphomas 8.7
Extranodal NK/T-cell lymphoma, nasal type 8.7
Subcutaneous panniculitis-like T-cell lymphoma 8.5
FAB M0 8.5
Cytomegalovirus pneumonia 8.4
AILD 8.3
NK-cell leukemia 8.3
Medullary carcinoma 8.2
Central European encephalitis 8.1
Zoonotic cutaneous leishmaniasis 8.1
Hodgkin's-like 8.0
Transplant glomerulopathy 7.9
angioimmunoblastic lymphadenopathy with dysproteinemia 7.9
T-cell lymphoma 7.7
Hepatosplenic T-cell lymphoma 7.6
anaplastic large cell lymphoma 7.5
T cell neoplasms 7.4
Lennert's lymphoma 7.3
Lymphatic metastasis 7.3
DFNA5 7.3
Peripheral T-cell lymphoma 7.3
CNS demyelinating disease 7.2
T-cell lymphomas 7.2
Eosinophilic pustular folliculitis 7.2
Post-kala-azar dermal leishmaniasis 7.1
Oral Cancer 7.1
FBL 7.1
Pseudolymphoma 7.1
pleural plaque 7.1
Civatte 7.1
LGL leukemia 7.1
Fowlpox 7.0
Lymphomatoid papulosis 6.9
Rasmussen encephalitis 6.9
Cytokine release syndrome 6.9
Klebsiella pneumoniae infection 6.9
ISH 6.8
Cerebral malaria 6.8
Stevens-Johnson syndrome 6.8
AML/MDS 6.7
ADCC 6.7
extensive stage SCLC 6.7
perineuritis 6.7
Viral myocarditis 6.7
Lewis Lung Carcinoma 6.6
Lentigo maligna 6.4
cowpox 6.4
Oral infection 6.3
bladder neoplasm 6.2
lymphocytic choriomeningitis 6.2
Macrophage activation syndrome 6.2
gastric neoplasm 6.2
Histiocytic necrotizing lymphadenitis 6.1
Hepatic necrosis 6.1
ocular herpes 6.1
panniculitis 6.0
blood cancer 6.0
drug hypersensitivity 5.9
refractory cytopenia with multilineage dysplasia 5.9
tubulovillous adenoma 5.9
angioimmunoblastic T-cell lymphoma 5.9
small airways disease 5.9
NS4 5.9
Tonsil 5.9
EL4 5.8
stage III melanoma 5.8
AA1 5.8
FDC 5.8
HLP 5.7
spindle cell sarcoma 5.7
immunopathology 5.7
more...
Symptom
hepatosplenomegaly 4.8
exhaustion 4.8
nasal discharge 3.8
splenomegaly 3.8
rigors 3.6
microbial colonization 3.2
nasal congestion 3.1
bone pain 2.6
abdominal discomfort 2.5
hepatomegaly 2.3
rhinorrhea 2.1
bradykinesia 2.0
asthenia 1.9
lethargy 1.8
anorexia 1.5
pelvic pain 1.3
acute stress 1.1
dizziness 1.0
paresthesia 1.0
starvation 1.0
ataxia 0.9
ENT 0.9
thinning 0.8
collapse 0.8
cough 0.7
respiratory distress 0.6
tinnitus 0.5
functional recovery 0.5
hypothermia 0.2
weakness 0.0
nausea and vomiting 0.0
vomiting -0.1
back pain -0.3
fatigue -0.4
erythema -0.4
dyspnea -0.5
acidity -0.7
abdominal pain -0.7
tremor -0.9
headache -1.0
diarrhea -1.0
angina -1.1
discomfort -1.2
nausea -1.3
discomfort -1.3
seizures -1.5
pain -2.2
Drug
3,4-Dichloroisocoumarin 9.8
Cefpiramide 8.1
Olomoucine 7.8
Belatacept 7.4
CED 7.2
Revlimid 7.1
Alefacept 7.0
IL-2 6.5
Basiliximab 6.5
Tolvaptan 6.5
Basiliximab 6.5
TRM 6.3
Lenalidomide 6.2
Sunitinib malate 6.1
Calcipotriol 5.9
IFN-gamma 5.9
Imiquimod 5.8
Ipilimumab 5.6
PDL 5.5
ID2 5.1
Exenatide 4.9
Fulvestrant 4.8
Tannic acid 4.7
CCL 4.5
Cetuximab 4.3
MTC 4.3
Piperacillin 4.2
Paraffin 4.1
Ginseng 4.1
Estrogens 4.1
Tuberculin 4.1
AMC 4.0
Dasatinib 4.0
Glide 3.9
CFS 3.9
PMEA 3.7
Prednisolone 3.7
Sorafenib 3.7
TAT 3.6
Isoniazid 3.3
CAM 3.3
CSF 3.3
CTC 3.2
ACT 3.2
G418 3.1
Etoposide 3.1
Herceptin 3.1
CTC 2.9
Meth 2.8
Bortezomib 2.7
IFN-beta 2.7
BH4 2.7
GEO 2.6
Ranitidine 2.6
Tacrolimus 2.5
CTX 2.5
Activin 2.5
G-CSF 2.5
ICI 2.4
MDS 2.1
Fragment 2.1
Imatinib 2.0
Ouabain 1.9
ETA 1.8
Alanine 1.8
Heme 1.6
Retinoic acid 1.5
p75 1.3
Asn 1.3
Portal 1.2
ABC 1.1
lysine 1.1
Adriamycin 1.1
Albumin 1.0
Angiotensin II 0.9
MAP 0.9
Histamine 0.8
Dermatol 0.8
CTX 0.8
CTX 0.8
more...
Enzyme
granzyme B 13.2
mast cell protease 5 12.2
granzyme M 11.8
granzyme K 11.1
TSP-1 10.9
caspase-6 7.9
cathepsin C 7.8
caspase-5 7.7
caspase-7 7.5
caspase-6 7.1
aspartase 7.1
caspase-5 7.0
cathepsin G 7.0
caspase-7 6.9
asparaginyl-tRNA synthetase 6.8
caspase-10 6.7
caspase-10 6.7
hydroxyprostaglandin dehydrogenase 6.6
neuropsin 6.6
chymase 6.5
proteinase-3 6.4
tryptase 6.4
macrophage elastase 6.1
SLB 6.0
neuropsin 5.9
caspase-2 5.9
Omi/HtrA2 5.8
carboxylesterase 5.8
p80 5.7
caspase-8 5.7
caspase-2 5.6
legumain 5.6
caspase-1 5.6
cruzipain 5.5
enterokinase 5.4
TdT 5.4
lysyl endopeptidase 5.3
clostripain 5.3
nucleoside hydrolase 5.1
caspase-3 5.0
caspase-11 4.8
caspase-11 4.8
caspase-4 4.7
cathepsin H 4.7
neutrophil elastase 4.7
arginase 4.7
ubiquitin-protein ligase 4.6
caspase-4 4.6
endoproteinase Glu-C 4.5
DNase II 4.5
MIP 4.4
ALDH 4.4
lactic acid dehydrogenase 4.4
cathepsin K 4.4
indoleamine 2,3-dioxygenase 4.3
lactic acid dehydrogenase 4.3
glucosylceramide synthase 4.3
N-acetylglucosaminyltransferase 4.3
lysin 4.2
firefly luciferase 4.1
tryptophan hydroxylase 4.0
cathepsin D 4.0
caspase-9 3.9
mu-calpain 3.8
adenine phosphoribosyltransferase 3.8
matrix metalloproteinase 9 3.7
CD10 3.7
lactic acid dehydrogenase 3.7
TAT 3.6
TACE 3.6
cathepsin B 3.5
chymotrypsin 3.5
APC 3.5
tryptophan 2,3-dioxygenase 3.5
prostate-specific membrane antigen 3.5
BMT 3.4
CD13 3.4
elastase 3.4
carboxypeptidase A 3.3
cathepsin L 3.3
more...
Compound
Xenazoic acid 13.2
Concanamycin A 8.8
diphenyl phosphonate 8.7
2-octynoic acid 8.6
4000 M 8.6
beta-Lapachone 7.7
Ziram 7.5
Arabinoxylan 6.9
Fast Blue B 6.7
CMK 6.6
NKT 6.5
IVE 6.5
1,1,2-trichloroethane 6.4
SHM 6.2
AT-101 6.2
AT-101 6.2
CD 3 6.1
AT-101 6.1
Dimethyl fumarate 6.1
3,4-dihydroxybenzaldehyde 6.0
Carnosic acid 6.0
DQ1 5.8
Nobiletin 5.7
pentanedioic acid 5.7
TNB 5.6
Mupirocin 5.6
Tumor Necrosis Factor 5.5
EBT 5.3
Interleukin-2 5.3
Serine 5.2
Alum 5.2
nonanoic acid 5.1
nonanoic acid 5.1
S-benzyl 5.1
nonanoic acid 5.1
nonanoic acid 5.0
MVA 5.0
Leflunomide 4.9
Cholic acid 4.9
TDT 4.9
Meloxicam 4.8
TNF 4.8
N-(4-hydroxyphenyl)retinamide 4.7
NOXA 4.7
AFC 4.6
DEK 4.6
Pentoxifylline 4.6
Poly(I:C) 4.5
PMA 4.5
nonanoic acid 4.4
Iodo 4.4
SP-1 4.4
SET 4.4
Venlafaxine 4.4
E-64 4.4
Naringin 4.3
DCB 4.3
Piperacillin 4.3
DCB 4.2
MTC 4.2
dATP 4.2
serine 4.2
Coenzyme A 4.2
Asp 4.1
Glu-Glu 4.1
Malate 4.1
DCB 4.1
Wortmannin 4.1
aspartic acid 4.1
ACI 4.1
aspartic acid 4.0
Camptothecin 4.0
Camptothecin 4.0
Camptothecin 4.0
Etanercept 4.0
aspartic acid 3.9
celastrol 3.9
Rapamycin 3.8
PMA 3.8
DCB 3.8
more...