Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.79 (
granzyme B
)
3,301
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
granzyme B
3287
perforin
1169
CD8
1063
CD4
608
IFN
516
cytokine
439
IL-2
280
interferon
251
CD56
203
Sep
196
TNF
179
IFN-gamma
177
granzyme A
167
IL-10
164
CD25
155
serine protease
154
Fas
151
lymphoid
146
Mol
142
caspase-3
141
Fas ligand
129
IL-15
117
CD28
116
interferon-gamma
115
PD-1
114
CD69
113
tumor necrosis factor
112
TCR
110
PFP
109
TIA-1
104
CD107a
100
IL-17
94
FasL
93
IL-4
89
interleukin-2
84
HLA
83
IL-6
80
CD20
79
MHC
78
T-bet
77
CD27
75
chemokine
72
CD16
72
CD30
70
NKG2D
67
Bcl-2
66
T cell receptor
63
IL-21
63
CD2
62
CD5
61
CD57
59
PD-L1
58
CTLA-4
57
granulysin
56
interferon gamma
55
CCR7
54
caspase-8
53
TNF-alpha
51
HLA-DR
49
CD127
48
CD62L
48
MHC class I
46
FOXP3
45
cytochrome c
44
Bid
44
major histocompatibility complex
43
CD103
40
TRAIL
37
natural killer cell
36
CD7
36
CD68
36
CXCR3
35
IL-18
35
CD95
35
CD19
34
NKp46
33
proteinase inhibitor 9
33
p53
33
CXCL10
33
STAT3
32
more...
Disease
tumor
875
cancer
636
lymphoma
152
HIV
136
melanoma
126
Epstein
119
leukemia
114
tumor growth
112
T-cell lymphoma
103
virus infection
101
influenza
87
cytomegalovirus
72
carcinoma
55
tumor progression
54
hepatocellular carcinoma
53
Hodgkin's disease
53
graft-versus-host disease
51
breast cancer
46
infectious diseases
44
tuberculosis
43
lung cancer
41
immunodeficiency
41
T-cell lymphomas
41
colorectal cancer
38
multiple sclerosis
37
Mycobacterium
36
squamous cell carcinoma
34
colon cancer
34
anaplastic large cell lymphoma
34
acute myeloid leukemia
32
metastases
31
diabetes
30
adenocarcinoma
29
AIDS
29
autoimmune disease
28
malaria
28
vaccinia
26
hepatitis C
24
lymphocytic choriomeningitis
24
systemic lupus erythematosus
24
Blocking
23
rheumatoid arthritis
23
type 1 diabetes
22
immunopathology
21
transient ischemic attack
21
tumorigenesis
20
herpes simplex
20
viremia
20
multiple myeloma
20
B-cell lymphoma
20
encephalomyelitis
19
non-small cell lung cancer
19
EBV infection
19
leishmaniasis
19
Stevens-Johnson syndrome
18
Infection
17
APC
17
SCID
16
prostate cancer
16
solid tumor
15
asthma
15
encephalitis
15
SDS
14
thrombocytopenia
14
non-Hodgkin's lymphoma
14
hepatitis
14
renal disease
14
hepatitis B
14
gastric cancer
14
enteropathy
14
rash
14
chronic hepatitis
14
primary tumor
13
chronic lymphocytic leukemia
13
pancreatic cancer
13
Chagas
13
lymphadenopathy
13
NOD
13
myelodysplastic syndrome
13
mycosis fungoides
13
more...
Symptom
exhaustion
40
splenomegaly
14
hepatosplenomegaly
13
pain
6
collapse
5
starvation
5
weakness
4
anorexia
4
cough
4
fatigue
4
respiratory distress
3
diarrhea
3
seizures
3
headache
3
vomiting
3
hepatomegaly
3
ataxia
3
abdominal pain
2
hypothermia
2
lethargy
2
thinning
2
bone pain
2
dizziness
2
nasal discharge
2
functional recovery
2
dyspnea
2
back pain
1
bradykinesia
1
tremor
1
nausea and vomiting
1
abdominal discomfort
1
acidity
1
tinnitus
1
discomfort
1
nasal congestion
1
erythema
1
paresthesia
1
ENT
1
acute stress
1
pelvic pain
1
discomfort
1
rhinorrhea
1
angina
1
asthenia
1
microbial colonization
1
nausea
1
rigors
1
Drug
IL-2
280
IFN-gamma
176
Dermatol
47
CSF
31
lysine
13
CED
9
CAM
6
CTX
6
Lenalidomide
5
Estrogens
4
Paraffin
4
TRM
3
ICI
3
PDL
3
Asn
3
MAP
3
Ginseng
3
G-CSF
3
ROS
3
TAT
3
CCL
3
Imiquimod
3
Belatacept
2
IFN-beta
2
Herceptin
2
G418
2
Cetuximab
2
ABC
2
Sorafenib
2
Prednisolone
2
ACT
2
Tolvaptan
2
AMC
2
Ipilimumab
2
Nephron
1
Adriamycin
1
vitamin E
1
PMEA
1
Bortezomib
1
CaCl2
1
CTC
1
Ouabain
1
Cefpiramide
1
Activin
1
ENT
1
ID2
1
Tuberculin
1
Olomoucine
1
Retinoic acid
1
BH4
1
Revlimid
1
CTC
1
Alefacept
1
Asthma
1
CTX
1
Etoposide
1
DNase I
1
Albumin
1
Isoniazid
1
Sunitinib malate
1
Leaf
1
Tacrolimus
1
GEO
1
Gel
1
Exenatide
1
CaCl2
1
Fulvestrant
1
Heme
1
3,4-Dichloroisocoumarin
1
Biopolymers
1
Histamine
1
Portal
1
Calcipotriol
1
Tannic acid
1
Glide
1
Piperacillin
1
Basiliximab
1
Dasatinib
1
MDS
1
CTX
1
more...
Enzyme
granzyme B
3301
TSP-1
168
caspase-3
118
ERK
73
caspase-8
36
mitogen-activated protein kinase
34
trypsin
33
caspase-1
32
cathepsin G
24
tryptase
24
APC
19
reverse transcriptase
17
carboxylesterase
17
caspase-7
17
lactate dehydrogenase
14
CD10
13
chymotrypsin
13
focal adhesion kinase
13
chymase
13
caspase-6
12
caspase-9
12
luciferase
12
MIP
11
neutrophil elastase
11
caspase-7
11
granzyme M
11
PARP
11
granzyme K
10
elastase
10
arginase
10
protein kinase
10
cathepsin C
9
P-glycoprotein
9
protein kinase C
9
TdT
8
MEK
8
RNA polymerase
8
alanine aminotransferase
8
cathepsin D
7
thrombin
7
caspase-6
7
proteasome
7
transcriptase
7
thromboplastin
6
tyrosinase
6
superoxide dismutase
6
plasmin
5
endonuclease
5
firefly luciferase
5
caspase-2
5
ACS
5
complex I
5
aspartate aminotransferase
5
cathepsin B
5
beta-galactosidase
5
caspase-2
4
glutathione peroxidase
4
CAD
4
RNase
4
CAD
4
cathepsin K
4
DNase
4
RNase
4
peroxidase
4
CAD
4
glutathione S-transferase
4
NO synthase
4
CD13
4
phosphatidylinositol 3-kinase
4
adenosine deaminase
3
p80
3
creatine kinase
3
NOS
3
TAT
3
tissue plasminogen activator
3
AST
3
BMT
3
cdc2
3
proteinase-3
3
DNA methyltransferase
3
more...
Compound
Dec
233
DNA
224
TNF
179
Clin
153
serine
125
Asp
63
cysteine
42
oxygen
39
calcium
39
alanine
29
NKT
24
arginine
22
lysine
21
tyrosine
19
PMA
18
aspartic acid
18
aspartic acid
18
aspartic acid
18
PMA
18
aspartic acid
18
methionine
15
retinoic acid
14
acetate
14
SDS
14
Serine
13
phosphate
13
cAMP
12
sulfate
12
Phe
12
galactose
12
leucine
12
TEM
11
glucose
10
chromium
10
sodium
9
His
9
water
9
MTT
9
Gly
8
creatinine
8
COS
8
hyaluronic acid
8
dUTP
8
ATP
8
BCR
8
boron
8
nitric oxide
8
ethanol
7
PEG
7
FK506
7
PEG
7
MDA
7
hydrogen
6
MEK
6
DBA
6
THP
6
CTX
6
DBA
6
CMK
6
GM1
6
DDP
6
DBA
6
THP
6
ADP-ribose
6
Interleukin-2
6
nitrogen
6
Curcumin
6
nickel
5
ACS
5
salt
5
Optimal
5
aluminum
5
ACS
5
SET
5
Ile
5
Cyclosporine
5
Rapamycin
5
glutamate
5
GMP
5
PGE2
5
more...