Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.79 (granzyme B)
3,301 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
granzyme B 3287
perforin 1169
CD8 1063
CD4 608
IFN 516
cytokine 439
IL-2 280
interferon 251
CD56 203
Sep 196
TNF 179
IFN-gamma 177
granzyme A 167
IL-10 164
CD25 155
serine protease 154
Fas 151
lymphoid 146
Mol 142
caspase-3 141
Fas ligand 129
IL-15 117
CD28 116
interferon-gamma 115
PD-1 114
CD69 113
tumor necrosis factor 112
TCR 110
PFP 109
TIA-1 104
CD107a 100
IL-17 94
FasL 93
IL-4 89
interleukin-2 84
HLA 83
IL-6 80
CD20 79
MHC 78
T-bet 77
CD27 75
chemokine 72
CD16 72
CD30 70
NKG2D 67
Bcl-2 66
T cell receptor 63
IL-21 63
CD2 62
CD5 61
CD57 59
PD-L1 58
CTLA-4 57
granulysin 56
interferon gamma 55
CCR7 54
caspase-8 53
TNF-alpha 51
HLA-DR 49
CD127 48
CD62L 48
MHC class I 46
FOXP3 45
cytochrome c 44
Bid 44
major histocompatibility complex 43
CD103 40
TRAIL 37
natural killer cell 36
CD7 36
CD68 36
CXCR3 35
IL-18 35
CD95 35
CD19 34
NKp46 33
proteinase inhibitor 9 33
p53 33
CXCL10 33
STAT3 32
more...
Disease
tumor 875
cancer 636
lymphoma 152
HIV 136
melanoma 126
Epstein 119
leukemia 114
tumor growth 112
T-cell lymphoma 103
virus infection 101
influenza 87
cytomegalovirus 72
carcinoma 55
tumor progression 54
hepatocellular carcinoma 53
Hodgkin's disease 53
graft-versus-host disease 51
breast cancer 46
infectious diseases 44
tuberculosis 43
lung cancer 41
immunodeficiency 41
T-cell lymphomas 41
colorectal cancer 38
multiple sclerosis 37
Mycobacterium 36
squamous cell carcinoma 34
colon cancer 34
anaplastic large cell lymphoma 34
acute myeloid leukemia 32
metastases 31
diabetes 30
adenocarcinoma 29
AIDS 29
autoimmune disease 28
malaria 28
vaccinia 26
hepatitis C 24
lymphocytic choriomeningitis 24
systemic lupus erythematosus 24
Blocking 23
rheumatoid arthritis 23
type 1 diabetes 22
immunopathology 21
transient ischemic attack 21
tumorigenesis 20
herpes simplex 20
viremia 20
multiple myeloma 20
B-cell lymphoma 20
encephalomyelitis 19
non-small cell lung cancer 19
EBV infection 19
leishmaniasis 19
Stevens-Johnson syndrome 18
Infection 17
APC 17
SCID 16
prostate cancer 16
solid tumor 15
asthma 15
encephalitis 15
SDS 14
thrombocytopenia 14
non-Hodgkin's lymphoma 14
hepatitis 14
renal disease 14
hepatitis B 14
gastric cancer 14
enteropathy 14
rash 14
chronic hepatitis 14
primary tumor 13
chronic lymphocytic leukemia 13
pancreatic cancer 13
Chagas 13
lymphadenopathy 13
NOD 13
myelodysplastic syndrome 13
mycosis fungoides 13
more...
Symptom
exhaustion 40
splenomegaly 14
hepatosplenomegaly 13
pain 6
collapse 5
starvation 5
weakness 4
anorexia 4
cough 4
fatigue 4
respiratory distress 3
diarrhea 3
seizures 3
headache 3
vomiting 3
hepatomegaly 3
ataxia 3
abdominal pain 2
hypothermia 2
lethargy 2
thinning 2
bone pain 2
dizziness 2
nasal discharge 2
functional recovery 2
dyspnea 2
back pain 1
bradykinesia 1
tremor 1
nausea and vomiting 1
abdominal discomfort 1
acidity 1
tinnitus 1
discomfort 1
nasal congestion 1
erythema 1
paresthesia 1
ENT 1
acute stress 1
pelvic pain 1
discomfort 1
rhinorrhea 1
angina 1
asthenia 1
microbial colonization 1
nausea 1
rigors 1
Drug
IL-2 280
IFN-gamma 176
Dermatol 47
CSF 31
lysine 13
CED 9
CAM 6
CTX 6
Lenalidomide 5
Estrogens 4
Paraffin 4
TRM 3
ICI 3
PDL 3
Asn 3
MAP 3
Ginseng 3
G-CSF 3
ROS 3
TAT 3
CCL 3
Imiquimod 3
Belatacept 2
IFN-beta 2
Herceptin 2
G418 2
Cetuximab 2
ABC 2
Sorafenib 2
Prednisolone 2
ACT 2
Tolvaptan 2
AMC 2
Ipilimumab 2
Nephron 1
Adriamycin 1
vitamin E 1
PMEA 1
Bortezomib 1
CaCl2 1
CTC 1
Ouabain 1
Cefpiramide 1
Activin 1
ENT 1
ID2 1
Tuberculin 1
Olomoucine 1
Retinoic acid 1
BH4 1
Revlimid 1
CTC 1
Alefacept 1
Asthma 1
CTX 1
Etoposide 1
DNase I 1
Albumin 1
Isoniazid 1
Sunitinib malate 1
Leaf 1
Tacrolimus 1
GEO 1
Gel 1
Exenatide 1
CaCl2 1
Fulvestrant 1
Heme 1
3,4-Dichloroisocoumarin 1
Biopolymers 1
Histamine 1
Portal 1
Calcipotriol 1
Tannic acid 1
Glide 1
Piperacillin 1
Basiliximab 1
Dasatinib 1
MDS 1
CTX 1
more...
Enzyme
granzyme B 3301
TSP-1 168
caspase-3 118
ERK 73
caspase-8 36
mitogen-activated protein kinase 34
trypsin 33
caspase-1 32
cathepsin G 24
tryptase 24
APC 19
reverse transcriptase 17
carboxylesterase 17
caspase-7 17
lactate dehydrogenase 14
CD10 13
chymotrypsin 13
focal adhesion kinase 13
chymase 13
caspase-6 12
caspase-9 12
luciferase 12
MIP 11
neutrophil elastase 11
caspase-7 11
granzyme M 11
PARP 11
granzyme K 10
elastase 10
arginase 10
protein kinase 10
cathepsin C 9
P-glycoprotein 9
protein kinase C 9
TdT 8
MEK 8
RNA polymerase 8
alanine aminotransferase 8
cathepsin D 7
thrombin 7
caspase-6 7
proteasome 7
transcriptase 7
thromboplastin 6
tyrosinase 6
superoxide dismutase 6
plasmin 5
endonuclease 5
firefly luciferase 5
caspase-2 5
ACS 5
complex I 5
aspartate aminotransferase 5
cathepsin B 5
beta-galactosidase 5
caspase-2 4
glutathione peroxidase 4
CAD 4
RNase 4
CAD 4
cathepsin K 4
DNase 4
RNase 4
peroxidase 4
CAD 4
glutathione S-transferase 4
NO synthase 4
CD13 4
phosphatidylinositol 3-kinase 4
adenosine deaminase 3
p80 3
creatine kinase 3
NOS 3
TAT 3
tissue plasminogen activator 3
AST 3
BMT 3
cdc2 3
proteinase-3 3
DNA methyltransferase 3
more...
Compound
Dec 233
DNA 224
TNF 179
Clin 153
serine 125
Asp 63
cysteine 42
oxygen 39
calcium 39
alanine 29
NKT 24
arginine 22
lysine 21
tyrosine 19
PMA 18
aspartic acid 18
aspartic acid 18
aspartic acid 18
PMA 18
aspartic acid 18
methionine 15
retinoic acid 14
acetate 14
SDS 14
Serine 13
phosphate 13
cAMP 12
sulfate 12
Phe 12
galactose 12
leucine 12
TEM 11
glucose 10
chromium 10
sodium 9
His 9
water 9
MTT 9
Gly 8
creatinine 8
COS 8
hyaluronic acid 8
dUTP 8
ATP 8
BCR 8
boron 8
nitric oxide 8
ethanol 7
PEG 7
FK506 7
PEG 7
MDA 7
hydrogen 6
MEK 6
DBA 6
THP 6
CTX 6
DBA 6
CMK 6
GM1 6
DDP 6
DBA 6
THP 6
ADP-ribose 6
Interleukin-2 6
nitrogen 6
Curcumin 6
nickel 5
ACS 5
salt 5
Optimal 5
aluminum 5
ACS 5
SET 5
Ile 5
Cyclosporine 5
Rapamycin 5
glutamate 5
GMP 5
PGE2 5
more...