Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.79 (
granzyme B
)
3,301
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
granzyme B
3287
perforin
1169
CD8
1063
CD4
608
IFN
516
cytokine
439
IL-2
280
interferon
251
CD56
203
Sep
196
TNF
179
IFN-gamma
177
granzyme A
167
IL-10
164
CD25
155
serine protease
154
Fas
151
lymphoid
146
Mol
142
caspase-3
141
Fas ligand
129
IL-15
117
CD28
116
interferon-gamma
115
PD-1
114
CD69
113
tumor necrosis factor
112
TCR
110
PFP
109
TIA-1
104
CD107a
100
IL-17
94
FasL
93
IL-4
89
interleukin-2
84
HLA
83
IL-6
80
CD20
79
MHC
78
T-bet
77
more...
Disease
tumor
875
cancer
636
lymphoma
152
HIV
136
melanoma
126
Epstein
119
leukemia
114
tumor growth
112
T-cell lymphoma
103
virus infection
101
influenza
87
cytomegalovirus
72
carcinoma
55
tumor progression
54
Hodgkin's disease
53
hepatocellular carcinoma
53
graft-versus-host disease
51
breast cancer
46
infectious diseases
44
tuberculosis
43
immunodeficiency
41
T-cell lymphomas
41
lung cancer
41
colorectal cancer
38
multiple sclerosis
37
Mycobacterium
36
colon cancer
34
anaplastic large cell lymphoma
34
squamous cell carcinoma
34
acute myeloid leukemia
32
metastases
31
diabetes
30
adenocarcinoma
29
AIDS
29
malaria
28
autoimmune disease
28
vaccinia
26
systemic lupus erythematosus
24
hepatitis C
24
lymphocytic choriomeningitis
24
more...
Symptom
exhaustion
40
splenomegaly
14
hepatosplenomegaly
13
pain
6
starvation
5
collapse
5
weakness
4
anorexia
4
cough
4
fatigue
4
diarrhea
3
respiratory distress
3
vomiting
3
seizures
3
hepatomegaly
3
headache
3
ataxia
3
abdominal pain
2
hypothermia
2
dizziness
2
lethargy
2
functional recovery
2
thinning
2
nasal discharge
2
bone pain
2
dyspnea
2
back pain
1
bradykinesia
1
tremor
1
nausea and vomiting
1
abdominal discomfort
1
acidity
1
ENT
1
tinnitus
1
discomfort
1
nasal congestion
1
discomfort
1
rhinorrhea
1
angina
1
asthenia
1
more...
Drug
IL-2
280
IFN-gamma
176
Dermatol
47
CSF
31
lysine
13
CED
9
CTX
6
CAM
6
Lenalidomide
5
Estrogens
4
Paraffin
4
Imiquimod
3
ROS
3
TRM
3
TAT
3
G-CSF
3
CCL
3
Asn
3
MAP
3
PDL
3
Ginseng
3
ICI
3
AMC
2
Tolvaptan
2
Prednisolone
2
ACT
2
IFN-beta
2
Cetuximab
2
Sorafenib
2
Herceptin
2
ABC
2
G418
2
Belatacept
2
Ipilimumab
2
Isoniazid
1
Leaf
1
Adriamycin
1
Bortezomib
1
CaCl2
1
GEO
1
more...
Enzyme
granzyme B
3301
TSP-1
168
caspase-3
118
ERK
73
caspase-8
36
mitogen-activated protein kinase
34
trypsin
33
caspase-1
32
tryptase
24
cathepsin G
24
APC
19
carboxylesterase
17
caspase-7
17
reverse transcriptase
17
lactate dehydrogenase
14
CD10
13
chymotrypsin
13
chymase
13
focal adhesion kinase
13
luciferase
12
caspase-9
12
caspase-6
12
PARP
11
granzyme M
11
MIP
11
neutrophil elastase
11
caspase-7
11
granzyme K
10
arginase
10
protein kinase
10
elastase
10
cathepsin C
9
P-glycoprotein
9
protein kinase C
9
RNA polymerase
8
alanine aminotransferase
8
TdT
8
MEK
8
thrombin
7
cathepsin D
7
more...
Compound
Dec
233
DNA
224
TNF
179
Clin
153
serine
125
Asp
63
cysteine
42
oxygen
39
calcium
39
alanine
29
NKT
24
arginine
22
lysine
21
tyrosine
19
aspartic acid
18
PMA
18
PMA
18
aspartic acid
18
aspartic acid
18
aspartic acid
18
methionine
15
retinoic acid
14
SDS
14
acetate
14
Serine
13
phosphate
13
galactose
12
Phe
12
sulfate
12
leucine
12
cAMP
12
TEM
11
glucose
10
chromium
10
His
9
sodium
9
MTT
9
water
9
Gly
8
dUTP
8
more...