Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.79 (
granzyme B
)
3,301
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
granzyme B
3287
perforin
1169
CD8
1063
CD4
608
IFN
516
cytokine
439
IL-2
280
interferon
251
CD56
203
Sep
196
TNF
179
IFN-gamma
177
granzyme A
167
IL-10
164
CD25
155
serine protease
154
Fas
151
lymphoid
146
Mol
142
caspase-3
141
more...
Disease
tumor
875
cancer
636
lymphoma
152
HIV
136
melanoma
126
Epstein
119
leukemia
114
tumor growth
112
T-cell lymphoma
103
virus infection
101
influenza
87
cytomegalovirus
72
carcinoma
55
tumor progression
54
Hodgkin's disease
53
hepatocellular carcinoma
53
graft-versus-host disease
51
breast cancer
46
infectious diseases
44
tuberculosis
43
more...
Symptom
exhaustion
40
splenomegaly
14
hepatosplenomegaly
13
pain
6
starvation
5
collapse
5
anorexia
4
fatigue
4
cough
4
weakness
4
diarrhea
3
respiratory distress
3
vomiting
3
ataxia
3
headache
3
seizures
3
hepatomegaly
3
abdominal pain
2
hypothermia
2
dyspnea
2
more...
Drug
IL-2
280
IFN-gamma
176
Dermatol
47
CSF
31
lysine
13
CED
9
CAM
6
CTX
6
Lenalidomide
5
Estrogens
4
Paraffin
4
G-CSF
3
ICI
3
CCL
3
TRM
3
Ginseng
3
TAT
3
MAP
3
PDL
3
Asn
3
more...
Enzyme
granzyme B
3301
TSP-1
168
caspase-3
118
ERK
73
caspase-8
36
mitogen-activated protein kinase
34
trypsin
33
caspase-1
32
cathepsin G
24
tryptase
24
APC
19
caspase-7
17
carboxylesterase
17
reverse transcriptase
17
lactate dehydrogenase
14
chymotrypsin
13
focal adhesion kinase
13
CD10
13
chymase
13
caspase-9
12
more...
Compound
Dec
233
DNA
224
TNF
179
Clin
153
serine
125
Asp
63
cysteine
42
oxygen
39
calcium
39
alanine
29
NKT
24
arginine
22
lysine
21
tyrosine
19
aspartic acid
18
aspartic acid
18
aspartic acid
18
PMA
18
aspartic acid
18
PMA
18
more...