Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.79 (granzyme B)
 3,301 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
granzyme B 3287
perforin 1169
CD8 1063
CD4 608
IFN 516
cytokine 439
IL-2 280
interferon 251
CD56 203
Sep 196
TNF 179
IFN-gamma 177
granzyme A 167
IL-10 164
CD25 155
serine protease 154
Fas 151
lymphoid 146
Mol 142
caspase-3 141
Fas ligand 129
IL-15 117
CD28 116
interferon-gamma 115
PD-1 114
CD69 113
tumor necrosis factor 112
TCR 110
PFP 109
TIA-1 104
CD107a 100
IL-17 94
FasL 93
IL-4 89
interleukin-2 84
HLA 83
IL-6 80
CD20 79
MHC 78
T-bet 77
CD27 75
chemokine 72
CD16 72
CD30 70
NKG2D 67
Bcl-2 66
IL-21 63
T cell receptor 63
CD2 62
CD5 61
CD57 59
PD-L1 58
CTLA-4 57
granulysin 56
interferon gamma 55
CCR7 54
caspase-8 53
TNF-alpha 51
HLA-DR 49
CD62L 48
CD127 48
MHC class I 46
FOXP3 45
Bid 44
cytochrome c 44
major histocompatibility complex 43
CD103 40
TRAIL 37
natural killer cell 36
CD68 36
CD7 36
CD95 35
CXCR3 35
IL-18 35
CD19 34
p53 33
CXCL10 33
proteinase inhibitor 9 33
NKp46 33
STAT3 32
CCR5 31
Cytokine 31
CD44 31
CD11b 31
CD86 30
CD38 30
4-1BB 30
gut 30
lymphokine 30
nodal 29
CD45 29
IL-8 29
GM-CSF 28
NK1 28
IL-13 28
CD95L 28
cathepsin G 28
CD80 28
CD43 27
SIV 27
human leukocyte antigen 27
CD40 26
CD40L 26
NKp30 25
MHC class II 25
IL-5 25
HLA-A2 25
NKG2A 25
Ki-67 25
CD11c 24
Gag 24
fused 24
tumor necrosis factor alpha 24
IL-2 receptor 24
lipopolysaccharide 23
IL-7 23
serine protease inhibitor 23
CD34 22
KLRG1 22
CD94 21
granzyme H 21
ERK 21
CPP32 21
PD1 21
glycoprotein 21
ICAM-1 20
CD39 20
mast cell 20
cage 20
CXCL9 20
TGF-beta 19
STAT1 19
CD161 19
B7-H3 18
mTOR 18
interleukin-10 18
STAT5 18
annexin V 18
IL-22 17
MR1 17
protease inhibitor 17
caspase-9 17
OX40 17
APC 17
CD14 17
LPS 17
cysteine protease 16
CD1d 16
CX3CR1 16
AKT 16
serglycin 16
NKp44 16
eomesodermin 16
membrane protein 16
membrane-bound 15
IL-23 15
chymase 15
RANTES 15
thymus 15
HLA class I 15
more...
Disease
tumor 875
cancer 636
lymphoma 152
HIV 136
melanoma 126
Epstein 119
leukemia 114
tumor growth 112
T-cell lymphoma 103
virus infection 101
influenza 87
cytomegalovirus 72
carcinoma 55
tumor progression 54
Hodgkin's disease 53
hepatocellular carcinoma 53
graft-versus-host disease 51
breast cancer 46
infectious diseases 44
tuberculosis 43
immunodeficiency 41
lung cancer 41
T-cell lymphomas 41
colorectal cancer 38
multiple sclerosis 37
Mycobacterium 36
squamous cell carcinoma 34
anaplastic large cell lymphoma 34
colon cancer 34
acute myeloid leukemia 32
metastases 31
diabetes 30
adenocarcinoma 29
AIDS 29
autoimmune disease 28
malaria 28
vaccinia 26
systemic lupus erythematosus 24
hepatitis C 24
lymphocytic choriomeningitis 24
Blocking 23
rheumatoid arthritis 23
type 1 diabetes 22
transient ischemic attack 21
immunopathology 21
multiple myeloma 20
tumorigenesis 20
B-cell lymphoma 20
viremia 20
herpes simplex 20
non-small cell lung cancer 19
EBV infection 19
leishmaniasis 19
encephalomyelitis 19
Stevens-Johnson syndrome 18
Infection 17
APC 17
SCID 16
prostate cancer 16
encephalitis 15
solid tumor 15
asthma 15
thrombocytopenia 14
gastric cancer 14
hepatitis B 14
SDS 14
non-Hodgkin's lymphoma 14
chronic hepatitis 14
renal disease 14
enteropathy 14
hepatitis 14
rash 14
chronic lymphocytic leukemia 13
lymphadenopathy 13
Chagas 13
pancreatic cancer 13
primary tumor 13
eosinophilia 13
myelodysplastic syndrome 13
NOD 13
mycosis fungoides 13
atherosclerosis 12
MCF 12
celiac disease 12
cirrhosis 12
lung carcinoma 12
acute lymphoblastic leukemia 11
panniculitis 11
Crohn's disease 11
sepsis 11
lupus 11
glioblastoma 11
carcinogenesis 11
plaque 11
sepsis 11
MIP 11
ulcerative colitis 10
B-cell lymphomas 10
colitis 10
metastatic melanoma 10
Leukemia 10
inflammatory bowel disease 10
ovarian cancer 10
glioma 10
adult T-cell leukemia/lymphoma 10
psoriasis 10
renal cell carcinoma 10
chronic lymphocytic leukemia 10
lymphoproliferative disorders 9
cervical cancer 9
lymphoblastic leukemia 9
liver cancer 9
pancytopenia 9
mastocytoma 9
dermatitis 9
pneumonia 9
hypertension 9
EMA 9
skin disease 9
lung metastases 8
liver cancer 8
TEM 8
hematologic malignancies 8
suicide 8
ADCC 8
secondary infection 8
drug hypersensitivity 8
TEM 8
arthritis 8
neuroblastoma 8
bladder cancer 8
herpes 8
dengue 8
liver metastases 8
bacterial infection 8
head and neck cancer 7
EL4 7
ischemia 7
stroke 7
myelopathy 7
osteosarcoma 7
rare disease 7
lupus 7
cowpox 7
RSV infection 7
heart failure 7
aggression 7
chronic obstructive pulmonary disease 7
sarcoma 7
Hepatocellular carcinoma 7
ISH 7
HAM 7
chronic myeloid leukemia 7
epithelial ovarian cancer 7
aplastic anemia 7
obesity 6
bronchiolitis 6
varicella 6
type 2 diabetes 6
Peripheral T-cell lymphoma 6
more...
Symptom
exhaustion 40
splenomegaly 14
hepatosplenomegaly 13
pain 6
collapse 5
starvation 5
weakness 4
anorexia 4
cough 4
fatigue 4
respiratory distress 3
diarrhea 3
seizures 3
headache 3
vomiting 3
hepatomegaly 3
ataxia 3
abdominal pain 2
hypothermia 2
lethargy 2
thinning 2
bone pain 2
dizziness 2
nasal discharge 2
functional recovery 2
dyspnea 2
back pain 1
bradykinesia 1
tremor 1
nausea and vomiting 1
abdominal discomfort 1
acidity 1
tinnitus 1
discomfort 1
nasal congestion 1
erythema 1
paresthesia 1
ENT 1
acute stress 1
pelvic pain 1
discomfort 1
rhinorrhea 1
angina 1
asthenia 1
microbial colonization 1
nausea 1
rigors 1
Drug
IL-2 280
IFN-gamma 176
Dermatol 47
CSF 31
lysine 13
CED 9
CTX 6
CAM 6
Lenalidomide 5
Paraffin 4
Estrogens 4
G-CSF 3
ICI 3
CCL 3
TAT 3
PDL 3
Imiquimod 3
Asn 3
Ginseng 3
MAP 3
TRM 3
ROS 3
AMC 2
Herceptin 2
Cetuximab 2
ABC 2
Tolvaptan 2
Prednisolone 2
Sorafenib 2
Belatacept 2
ACT 2
IFN-beta 2
G418 2
Ipilimumab 2
Nephron 1
Adriamycin 1
vitamin E 1
PMEA 1
Bortezomib 1
CaCl2 1
CTC 1
Ouabain 1
Cefpiramide 1
Activin 1
ENT 1
ID2 1
Tuberculin 1
Olomoucine 1
Retinoic acid 1
Revlimid 1
Angiotensin II 1
CTC 1
Imatinib 1
Basiliximab 1
Meth 1
Alefacept 1
Asthma 1
MTC 1
CFS 1
p75 1
Isoniazid 1
Sunitinib malate 1
Leaf 1
Tacrolimus 1
GEO 1
3,4-Dichloroisocoumarin 1
Etoposide 1
DNase I 1
Albumin 1
Biopolymers 1
Histamine 1
Portal 1
Calcipotriol 1
BH4 1
Gel 1
Exenatide 1
CaCl2 1
Fulvestrant 1
Heme 1
Tannic acid 1
Glide 1
Ranitidine 1
CTX 1
Piperacillin 1
Basiliximab 1
Dasatinib 1
MDS 1
CTX 1
NH3 1
Fragment 1
CaCl2 1
ROC 1
ETA 1
Alanine 1
Enzyme
granzyme B 3301
TSP-1 168
caspase-3 118
ERK 73
caspase-8 36
mitogen-activated protein kinase 34
trypsin 33
caspase-1 32
cathepsin G 24
tryptase 24
APC 19
caspase-7 17
reverse transcriptase 17
carboxylesterase 17
lactate dehydrogenase 14
chymotrypsin 13
CD10 13
chymase 13
focal adhesion kinase 13
caspase-9 12
luciferase 12
caspase-6 12
neutrophil elastase 11
PARP 11
MIP 11
caspase-7 11
granzyme M 11
arginase 10
granzyme K 10
elastase 10
protein kinase 10
P-glycoprotein 9
protein kinase C 9
cathepsin C 9
alanine aminotransferase 8
MEK 8
TdT 8
RNA polymerase 8
transcriptase 7
thrombin 7
caspase-6 7
cathepsin D 7
proteasome 7
thromboplastin 6
tyrosinase 6
superoxide dismutase 6
cathepsin B 5
caspase-2 5
firefly luciferase 5
complex I 5
endonuclease 5
aspartate aminotransferase 5
ACS 5
beta-galactosidase 5
plasmin 5
NO synthase 4
glutathione peroxidase 4
caspase-2 4
RNase 4
peroxidase 4
cathepsin K 4
DNase 4
RNase 4
phosphatidylinositol 3-kinase 4
CAD 4
glutathione S-transferase 4
CAD 4
CAD 4
CD13 4
p80 3
NOS 3
enterokinase 3
BMT 3
matrix metalloproteinase 9 3
collagenase 3
cdc2 3
DNA methyltransferase 3
AMP-activated protein kinase 3
tryptophan hydroxylase 3
lysozyme 3
calcineurin 3
adenosine deaminase 3
papain 3
TAT 3
AST 3
creatine kinase 3
tissue plasminogen activator 3
adenosine deaminase 3
indoleamine 2,3-dioxygenase 3
aspartase 3
proteinase-3 3
phosphodiesterase 2
caspase-10 2
ALDH 2
caspase-10 2
ubiquitin-protein ligase 2
catalase 2
pepsin 2
GSK 2
phosphoinositide 3-kinase 2
lysin 2
AMPK 2
heme oxygenase 2
alkaline phosphatase 2
caspase-5 2
neuraminidase 2
glyceraldehyde-3-phosphate dehydrogenase 2
cathepsin L 2
cruzipain 2
lysyl endopeptidase 2
mast cell protease 5 2
asparaginase 2
MAP 2
Omi/HtrA2 2
BAL 2
AMPK 2
prostate-specific membrane antigen 2
urokinase-type plasminogen activator 2
legumain 2
topoisomerase 1
prostate-specific antigen 1
histone acetyltransferase 1
hyaluronidase 1
endoglycosidase H 1
phospholipase A2 1
MMP-3 1
phospholipase C 1
SPC 1
nucleoside hydrolase 1
caspase-4 1
caspase-11 1
NADPH oxidase 1
NADPH oxidase 1
adenylate kinase 1
diacylglycerol kinase 1
caspase-5 1
MDR 1
caspase-11 1
lysyl oxidase 1
neuropsin 1
urease 1
sialidase 1
xanthine dehydrogenase 1
neuropsin 1
endoproteinase Glu-C 1
TACE 1
clostripain 1
glutathione reductase 1
peroxiredoxin 1
N-acetylglucosaminyltransferase 1
lactic acid dehydrogenase 1
Thy1 1
lactic acid dehydrogenase 1
glutaminase 1
asparaginyl-tRNA synthetase 1
hydroxyprostaglandin dehydrogenase 1
HIV-1 protease 1
caspase-4 1
kallikrein 1
carboxypeptidase A 1
more...
Compound
Dec 233
DNA 224
TNF 179
Clin 153
serine 125
Asp 63
cysteine 42
calcium 39
oxygen 39
alanine 29
NKT 24
arginine 22
lysine 21
tyrosine 19
PMA 18
aspartic acid 18
PMA 18
aspartic acid 18
aspartic acid 18
aspartic acid 18
methionine 15
retinoic acid 14
acetate 14
SDS 14
phosphate 13
Serine 13
Phe 12
galactose 12
sulfate 12
leucine 12
cAMP 12
TEM 11
glucose 10
chromium 10
MTT 9
sodium 9
His 9
water 9
nitric oxide 8
Gly 8
boron 8
creatinine 8
ATP 8
dUTP 8
BCR 8
hyaluronic acid 8
COS 8
PEG 7
MDA 7
PEG 7
FK506 7
ethanol 7
THP 6
CTX 6
Interleukin-2 6
DDP 6
CMK 6
Curcumin 6
DBA 6
THP 6
hydrogen 6
ADP-ribose 6
GM1 6
DBA 6
nitrogen 6
DBA 6
MEK 6
aluminum 5
nickel 5
ACS 5
Cyclosporine 5
Optimal 5
PGE2 5
ACS 5
Rapamycin 5
Ile 5
glutamate 5
SET 5
GMP 5
salt 5
dATP 4
aldehyde 4
Histone 4
tryptophan 4
aldehyde 4
formaldehyde 4
glucose-6-phosphate 4
Tumor Necrosis Factor 4
AMP 4
PPD 3
iodine 3
NH2 3
PPD 3
GSH 3
tryptophan 3
MVA 3
diacetate 3
threonine 3
vitamin D 3
proline 3
ICI 3
PGE 3
BCG 3
ADP 3
zinc 3
iron 3
ADP 3
ADP 3
urea 3
tryptophan 3
tryptophan 3
GSH 3
1,1,2-trichloroethane 2
TNM 2
potassium 2
MAP 2
TAP 2
ammonium 2
Substance P 2
Prednisolone 2
AFC 2
Ara-C 2
Pentoxifylline 2
isopropanol 2
Phosphatidylinositol 2
Alum 2
ABL 2
NMDA 2
PAM 2
NTA 2
strontium 2
Triton X-100 2
SPF 2
PEI 2
MCA 2
Cbl 2
PEI 2
BAL 2
Wortmannin 2
CO2 2
MCA 2
uridine 2
ACI 2
Estrogen 2
cobalt 2
xylose 2
Estrogen 2
Mg2+ 2
E-64 2
Neuronal 2
neopterin 2
CAM 2
INH 2
GTP 2
Progesterone 2
CAP 2
Concanamycin A 2
glutamic acid 2
Panam 1
Piperacillin 1
more...