Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.73 (urokinase-type plasminogen activator)
 10,685 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
tumor necrosis factor (ligand) superfamily, member 12 11.5
SERPINE2 protein 11.5
urokinase plasminogen activator 11.5
cell division cycle 7 homolog 11.5
killer cell immunoglobulin-like receptor 2DL4 11.5
u-PA 11.5
C10orf55 11.5
32KD 11.5
urokinase-type plasminogen activator 11.5
PAI-2 10.8
CDC91L1 10.5
growth and transformation-dependent protein 10.5
Serase-1B 10.5
PLAU protein 10.5
DC33 10.5
LRP-DIT 10.5
C9orf46 10.5
uPAR 10.3
CD87 10.3
UEF 10.2
plasminogen activator, urokinase 10.1
plasminogen activator inhibitor 2 10.1
low density lipoprotein-related protein 1 10.0
KIAA0709 10.0
PN-I 10.0
Urokinase plasminogen activator receptor 9.9
Plasminogen 9.8
urokinase plasminogen activator receptor 9.8
tryptase epsilon 9.7
plasminogen 9.7
PLAU 9.6
tPA 9.6
Beta-transducin repeat containing 9.5
kallikrein 12 9.5
SNRPB2 9.5
NET5 9.5
plasmin precursor 9.5
calpain 14 9.5
FIB2 9.5
insulin-like growth factor type II receptor 9.4
TMPRSS9 9.4
C4.4A 9.3
macrophage inflammatory protein 3 9.2
SERPINB13 9.2
S100E 9.2
Kallikrein 5 9.2
Epithelial membrane protein 1 9.2
SERPINB12 9.2
PAI1 mRNA 9.2
plasminogen activator inhibitor 9.2
Plasmin 9.2
plasminogen activator inhibitor-1 9.1
headpin 9.1
UPA 9.0
inhibitor-1 9.0
CSIG 9.0
APOL2 9.0
G protein-coupled receptor 124 9.0
SAP-3 9.0
DHX33 protein 9.0
Pim-1 oncogene 9.0
PLA 8.9
Urokinase plasminogen activator 8.8
GFRA3 8.8
alpha 2-plasmin inhibitor 8.8
PAI1 8.8
PN-II 8.7
PAI 8.7
tissue factor pathway inhibitor-2 8.6
plasminogen-like 8.6
nexin 8.6
PGA5 8.5
SLC8A2 8.5
BRMS1 protein 8.5
SPRR2B 8.5
gamma hENaC 8.5
neurofilament triplet L protein 8.5
regulatory subunit RI alpha 8.5
MPS7 8.5
FSAP 8.4
more...
Disease
RESDX 11.5
Coronary artery reocclusion 11.0
stage IV cervical cancer 10.0
Systemic fibrinogenolysis 9.5
Acute transmural myocardial infarction 9.5
Hepatic lymphoma 9.2
GFD 8.7
stage II cervical cancer 8.6
Myocardial hemorrhage 8.5
Chronic empyema 8.4
Basilar artery thrombosis 8.1
Bacterial pericarditis 7.8
KAL2 7.8
Renal artery occlusion 7.7
Thromboembolic stroke 7.6
Plasminogen deficiency 7.5
HRA 7.4
gastric cancer stage 7.3
Disseminated cancer 7.3
Refractory angina 7.3
Paget-Schroetter syndrome 7.3
Progression of prostate cancer 7.2
postphlebitic syndrome 7.1
PLAT 7.1
ovarian cancer stage 7.1
SPG6 6.8
Pleural infection 6.8
Central retinal artery occlusion 6.8
Acute massive pulmonary embolism 6.7
platelet disorder 6.7
Phlegmasia cerulea dolens 6.7
Superior sagittal sinus thrombosis 6.6
Primary antiphospholipid syndrome 6.5
Scott syndrome 6.4
Segmental demyelination 6.4
Masugi nephritis 6.4
cerebrovascular occlusion 6.4
varicose ulcer 6.4
coronary thrombosis 6.4
Thrombus 6.3
Brain lesion 6.3
Embolic stroke 6.2
Cardiac rupture 6.2
tuberculous effusion 6.2
XDP 6.2
Left ventricular thrombus 6.1
Pulmonary thromboembolism 6.1
Extrahepatic cholestasis 6.1
Diffuse alveolar damage 6.1
ovarian tumors of low malignant potential 6.1
ATRA syndrome 6.0
Ehrlich Ascites Tumor 6.0
hypofibrinogenemia 5.9
metastatic endometrial cancer 5.9
Intracardiac thrombus 5.9
HGF 5.8
Angiostrongyliasis 5.8
Q wave MI 5.8
Portal vein thrombosis 5.8
fibrothorax 5.7
Botryomycosis 5.7
Pannus 5.7
anteroseptal myocardial infarction 5.7
AOI 5.6
cerebral thrombosis 5.6
superficial keratitis 5.5
Spinal epidural hematoma 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
AT3 5.5
vascular obstruction 5.5
Plastic bronchitis 5.5
stage III breast cancer 5.4
anterolateral myocardial infarction 5.4
more...
Symptom
Dull pain 9.5
Refractory angina pectoris 8.2
finger pain 6.3
hemihypesthesia 5.9
swollen leg 5.7
disturbed balance 5.3
Pain at rest 5.1
consciousness disturbance 4.7
facial droop 4.6
autodigestion 4.2
hypalgesia 4.1
asynergy 3.8
chest pain 3.3
flank pain 3.3
angina 3.1
cyanosis 3.0
Scratch 2.9
hemiplegia 2.9
abdominal fullness 2.9
loss of balance 2.7
neurological disability 2.7
exertional dyspnea 2.6
spasm 2.5
Decreased activity 2.5
hypocapnia 2.4
excessive sweating 2.4
flushing 2.4
Fluctuation 2.3
neck stiffness 2.3
dysarthria 2.2
tachypnea 2.2
acute abdominal pain 2.2
right upper quadrant pain 2.1
paraparesis 2.1
hyperoxia 2.0
groin pain 2.0
chest tightness 2.0
intestinal bleeding 1.9
rigors 1.9
wrist pain 1.8
livedo 1.8
general problem 1.8
shortness of breath 1.8
functional recovery 1.7
oliguria 1.7
dysesthesia 1.7
paresis 1.6
respiratory distress 1.6
HSA 1.6
dyspnea 1.6
dry skin 1.6
syncope 1.5
hypersomnia 1.5
hypoproteinemia 1.4
rhinorrhea 1.4
epigastric pain 1.4
pallor 1.2
nasal discharge 1.1
lethargy 1.1
skin damage 1.0
anosmia 1.0
hemoptysis 1.0
menopausal symptoms 0.9
numbness 0.8
abdominal pain 0.7
neck pain 0.6
leg pain 0.5
blurred vision 0.5
chills 0.5
bradykinesia 0.3
vertigo 0.3
dysuria 0.3
hypercapnia 0.2
regurgitation 0.1
thinning 0.1
collapse 0.1
hypothermia 0.0
vomiting 0.0
back pain -0.0
bone pain -0.1
more...
Drug
uPA 11.4
Urokinase 10.9
Warfarin potassium 10.0
Ethyl icosapentate 10.0
Pamiteplase 9.2
Prolyse 9.2
Esberiven 9.0
Lanoteplase 8.7
Monteplase 8.7
Desmoteplase 8.2
Streptokinase 8.2
Alteplase 8.2
Alteplase 8.1
Brinase 8.1
Ancrod 8.1
Alteplase 8.0
Heparin sodium 8.0
Activase 8.0
Capravirine 8.0
Batimastat 7.8
Batimastat 7.8
Indisulam 7.7
Abarelix 7.5
Tenecteplase 7.3
Pentastarch 7.2
L-Homoarginine 6.9
Gabexate mesilate 6.9
Humegon 6.8
Fampridine 6.8
Sodium phenylbutyrate 6.7
DFP 6.5
Pemetrexed disodium 6.4
Marimastat 6.4
Aprotinin 6.3
Ozagrel 6.1
Sulfamylon 6.0
Piretanide 5.9
CTA 5.8
Beraprost 5.8
Coumadin 5.7
Tiaprofenic acid 5.6
Cetrorelix 5.5
Hyperforin 5.5
Radicicol 5.5
Tipifarnib 5.4
KAN 5.4
Orgaran 5.4
Amiloride 5.3
Abciximab 5.3
Ciglitazone 5.3
Panitumumab 5.2
Gelatin 5.1
Antithrombin III 5.1
Dalteparin 5.0
Amiloride 5.0
Azacytidine 5.0
Hydroxyethylstarch 4.8
DDAVP 4.8
DDAVP 4.8
CA-074 4.7
Ulinastatin 4.7
Sodium citrate 4.7
Sodium citrate 4.7
Sesamol 4.7
Argatroban 4.7
Poudre 4.7
KGF 4.6
Compound 15 4.6
Norplant 4.6
Iopromide 4.5
Trabectedin 4.4
Molsidomine 4.3
GEO 4.3
CPZ 4.2
CET 4.2
Cibacron Blue 4.2
CCL 4.2
Calcipotriol 4.2
Swainsonine 4.2
L-Asparaginase 4.1
more...
Enzyme
urokinase-type plasminogen activator 11.5
kallikrein 12 10.0
plasmin 9.4
tissue plasminogen activator 9.1
complement subcomponent C1r 8.7
Mucor pusillus rennin 8.6
stratum corneum tryptic enzyme 8.4
prostase 8.4
hepsin 8.0
hepsin 8.0
matriptase 8.0
ancrod 8.0
matriptase 7.7
neurosin 7.5
macrophage elastase 7.4
stromelysin-3 7.3
bacillolysin 7.2
thrombin-activatable fibrinolysis inhibitor 7.2
fibrolase 7.1
deuterolysin 7.0
matrix metalloproteinase 2 6.7
prostasin 6.7
MMP-3 6.6
kallikrein 6.6
matrix metalloproteinase 9 6.5
tissue kallikrein 6.5
coagulation factor XIa 6.3
stratum corneum chymotryptic enzyme 6.3
MMP 6.2
GPI-specific phospholipase C 6.2
interstitial collagenase 6.0
histidase 6.0
aureolysin 6.0
endoproteinase Asp-N 5.9
cathepsin G 5.9
cathepsin B 5.8
KLK13 5.8
carboxypeptidase B 5.7
site-1 protease 5.7
thrombin 5.7
fumarylacetoacetate hydrolase 5.7
MSAS 5.7
KLK7 5.6
carboxypeptidase D 5.6
cathepsin V 5.6
collagenase 3 5.6
Hageman factor 5.5
DFPase 5.5
cathepsin L 5.4
exonuclease VII 5.4
cathepsin D 5.4
neutrophil elastase 5.2
collagenase 5.2
clotting enzyme 5.1
thromboplastin 5.1
cancer procoagulant 5.0
elastase 4.9
phosphatidylinositol phospholipase C 4.9
cathepsin C 4.9
neuropsin 4.9
HCS 4.9
pregnancy-associated plasma protein-A 4.8
mutarotase 4.8
acetylserotonin O-methyltransferase 4.7
pantetheinase 4.7
enterokinase 4.7
acrosin 4.7
alpha-methylacyl-CoA racemase 4.7
PI-PLC 4.7
chymotrypsin 4.7
sulfhydryl oxidase 4.6
cathepsin H 4.6
trypsin 4.6
thermolysin 4.6
oligopeptidase B 4.6
hatching enzyme 4.5
C3b inactivator 4.5
tripeptidase 4.5
tryptase 4.5
APC 4.5
more...
Compound
Sinulariolide 10.0
C29H36O10 10.0
phenylmethanesulfonic acid 9.5
Plasmin 9.4
Adchnon 9.2
benzenecarboximidamide 8.7
BCDR 8.7
6-aminohexanoic acid 8.3
6-aminohexanoic acid 8.3
3-aminophenylalanine 8.1
diphenyl phosphonate 8.0
Aeroplysinin-1 7.7
Z-Gly 7.6
PAR 7.6
Thiodiglycol 7.1
Fibrin 7.1
Acacetin 7.1
Tranexamic acid 7.0
5-aminoisophthalic acid 6.8
LLY 6.7
Peonidin 6.7
Avarol 6.7
Bullatacin 6.6
Mesterolone 6.6
Carboquone 6.5
FDP 6.5
Diallyl disulfide 6.5
Galactan 6.5
Diallyl disulfide 6.5
Caprolactam 6.4
Diisopropyl fluorophosphate 6.4
2,5-piperazinedione 6.4
Abietic acid 6.4
Bisdemethoxycurcumin 6.4
ITG 6.3
Valyl 6.3
Sulfamylon 6.3
Deguelin 6.2
ATF 6.2
PAMBA 6.2
Carboquone 6.2
Carboquone 6.2
Carboquone 6.2
Carboquone 6.2
Papaverine hydrochloride 6.1
Salicin 6.1
Salicin 6.1
FCB 6.0
benzenesulfonyl fluoride 5.9
Chymostatin 5.8
Tazarotene 5.8
N-acetylserine 5.8
Thrombin 5.7
Phenethyl isothiocyanate 5.7
Eupatilin 5.7
8-quinolinyl 5.7
Fibrinogen 5.6
Dermatan sulfate 5.6
2,2-dimethoxypropane 5.6
Zaleplon 5.6
INN 5.5
Fibrinopeptide A 5.5
Hyperforin 5.5
Dianabol 5.5
Mr 30 5.5
Benazepril 5.4
Garcinol 5.4
Anethole 5.4
Benzamidine 5.4
Geranylgeranylacetone 5.4
Flavanone 5.3
Amiloride 5.3
Butein 5.2
Cefmetazole 5.2
Heparin 5.1
Econazole 5.1
Withaferin A 5.1
Phthalocyanine 5.0
Deoxyspergualin 5.0
Noscapine 5.0
more...