Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.73 (urokinase-type plasminogen activator)
10,685 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein urokinase-type plasminogen activator 9466 plasminogen 2854 PLA 2635 urokinase plasminogen activator 1175 plasminogen activator inhibitor-1 1174 uPAR 1007 plasminogen activator inhibitor 821 Sep 717 tissue plasminogen activator 713 thrombin 606 fibrinogen 590 Plasminogen 576 u-PA 528 Mol 511 serine protease 447 matrix metalloproteinase 406 MMP-9 371 collagen 335 MMP-2 332 tPA 320 vitronectin 292 PAI-2 275 SDS 246 fibronectin 245 vascular endothelial growth factor 198 Plasmin 188 inhibitor-1 182 PAR 164 PAI 161 epidermal growth factor 154 cytokine 146 kallikrein 144 hepatocyte growth factor 142 metalloproteinase 130 ERK1 129 tissue factor 128 urokinase plasminogen activator receptor 119 CD87 118 EPA 116 serine protease inhibitor 115 ERK 115 tumor necrosis factor 114 VEGF 113 p38 111 casein 111 collagenase 109 MMP-1 108 glycoprotein 106 albumin 103 insulin 98 MAPK 98 MMP 93 E-cadherin 93 matrix metalloproteinase 2 92 cell surface receptor 91 prothrombin 91 nexin 91 polypeptide 89 AP-1 89 antithrombin III 89 factor Xa 88 TIMP-2 85 chymotrypsin 85 p53 82 MMP9 82 TGF-beta 80 cathepsin B 79 thromboplastin 74 lipopolysaccharide 74 trypsin inhibitor 73 transforming growth factor-beta 72 MMP-3 71 PC-3 69 fused 69 plasminogen activator inhibitor 2 69 stromelysin 68 TNF 67 tyrosine kinase 66 protein C 65 antithrombin 65 more...

Disease cancer 1865 tumor 1689 breast cancer 562 metastases 372 carcinoma 367 acute myocardial infarction 309 tumor growth 255 tumor progression 253 SDS 246 myocardial infarction 215 stroke 212 prostate cancer 208 melanoma 199 pulmonary embolism 194 ischemia 171 deep vein thrombosis 134 adenocarcinoma 130 ovarian cancer 126 MCF 117 hepatocellular carcinoma 116 atherosclerosis 115 lung cancer 104 SCID 102 carcinogenesis 92 squamous cell carcinoma 89 fibrosarcoma 87 diabetes 87 gastric cancer 86 colon cancer 85 colorectal cancer 82 glioma 80 lung carcinoma 78 tumorigenesis 77 primary tumor 76 plaque 76 glioblastoma 74 hypertension 72 leukemia 66 disseminated intravascular coagulation 65 sepsis 61 pancreatic cancer 59 Thrombus 58 proteinuria 56 osteosarcoma 53 sepsis 52 rheumatoid arthritis 50 tumor angiogenesis 49 aggressiveness 48 HGF 48 epithelial ovarian cancer 45 coronary artery disease 41 heart failure 41 uterus 40 thrombocytopenia 40 non-small cell lung cancer 40 renal disease 39 SEM 39 glomerulosclerosis 39 empyema 39 Alzheimer's disease 39 arthritis 38 cerebral infarction 36 Infection 36 infectious diseases 36 obesity 36 osteoarthritis 35 nephrotic syndrome 35 cardiovascular disease 34 pneumonia 33 coronary thrombosis 33 cerebral ischemia 32 lung metastases 32 HIV 31 pulmonary fibrosis 31 unstable angina 30 glomerulonephritis 30 cirrhosis 30 metastatic breast cancer 29 hepatitis C 29 multiple myeloma 29 more...

Symptom pain 68 angina 61 chest pain 58 dyspnea 28 anesthesia 27 respiratory distress 20 abdominal pain 17 seizures 15 headache 15 functional recovery 15 spasm 14 vomiting 11 flushing 11 collapse 10 cyanosis 10 hemiplegia 10 syncope 9 weakness 9 flank pain 7 consciousness disturbance 7 exertional dyspnea 7 hyperoxia 7 starvation 6 dysarthria 6 paresis 6 hypothermia 6 shortness of breath 6 nausea 6 lethargy 4 tachypnea 4 back pain 4 thinning 4 exhaustion 4 paraparesis 4 stigma 4 hemoptysis 4 diarrhea 3 epigastric pain 3 tremor 3 acute abdominal pain 3 acidity 3 discomfort 3 discomfort 3 hypercapnia 3 vertigo 3 asynergy 3 HSA 3 regurgitation 3 hypocapnia 3 numbness 3 disturbed balance 3 fatigue 3 neurological disability 2 cough 2 rhinorrhea 2 sleepiness 2 low back pain 2 oliguria 2 Ill 2 overweight 2 insomnia 2 nausea and vomiting 2 erythema 2 analgesia 2 autodigestion 2 chills 2 neck pain 2 pallor 2 agitation 2 nasal discharge 1 Decreased activity 1 swollen leg 1 paresthesia 1 anosmia 1 intestinal bleeding 1 pelvic pain 1 loss of balance 1 wrist pain 1 dysuria 1 acute stress 1 more...

Drug uPA 1874 Urokinase 388 lysine 298 Cardiovasc 162 Dermatol 93 Streptokinase 57 CSF 44 Gel 31 DFP 28 CTA 27 Aprotinin 25 Alteplase 24 Alteplase 23 Alteplase 22 IFN-gamma 21 Gelatin 20 MAP 20 Asn 20 Amiloride 20 Amiloride 20 nitroglycerin 17 Norplant 14 Dial 13 Nephron 13 Nephron 13 CaCl2 12 CaCl2 12 CaCl2 12 ROS 11 GEO 10 CAM 10 EE2 9 Ancrod 9 DDAVP 9 DDAVP 9 ETS 9 CCL 8 ABC 8 vitamin E 8 G-CSF 8 Ringer's solution 8 Angiotensin II 7 Batimastat 7 Fluorescein 7 Adriamycin 7 DNase I 7 ROC 7 Batimastat 7 Fluorescein 6 Coumadin 6 Antithrombin III 6 ACT 5 IL-2 5 Leaf 5 Fragment 5 ascorbate 5 G418 5 Alanine 5 Portal 4 Retinoic acid 4 FeCl3 4 Activase 4 Indomethacin 4 Dalteparin 4 Herceptin 4 Abciximab 4 TAT 4 Captopril 4 MRC 4 Monit 4 KGF 4 PTH 3 Bayer 3 ICI 3 Glycyrrhiza 3 Lovastatin 3 AMC 3 TTC 3 BLM 3 Cibacron Blue 3 more...

Enzyme urokinase-type plasminogen activator 10685 tissue plasminogen activator 2035 plasmin 2013 thrombin 590 mitogen-activated protein kinase 342 trypsin 337 ERK 246 collagenase 226 kallikrein 199 thromboplastin 150 protein kinase C 138 APC 121 MMP-3 115 MMP 107 focal adhesion kinase 105 elastase 94 chymotrypsin 94 protein kinase 91 MEK 90 matrix metalloproteinase 2 82 cathepsin B 79 matrix metalloproteinase 9 67 cathepsin D 57 phospholipase C 54 neutrophil elastase 52 creatine kinase 38 tissue kallikrein 37 phosphatidylinositol 3-kinase 36 reverse transcriptase 36 matriptase 35 cathepsin G 35 matriptase 33 caspase-3 32 luciferase 32 peroxidase 31 alkaline phosphatase 29 cathepsin L 28 AMPK 23 catalase 23 interstitial collagenase 21 tryptase 21 renin 20 papain 20 lactate dehydrogenase 19 ancrod 19 prostate-specific antigen 19 adenylate cyclase 17 CD10 16 ACE 16 thermolysin 15 furin 15 proteasome 15 IKK 14 transglutaminase 14 lipoprotein lipase 13 RNase 13 ACS 13 hepsin 13 glutathione S-transferase 13 superoxide dismutase 13 pepsin 13 phosphoinositide 3-kinase 13 subtilisin 13 hepsin 13 neuraminidase 13 phospholipase A2 12 RNA polymerase 12 thrombin-activatable fibrinolysis inhibitor 12 chloramphenicol acetyltransferase 12 enolase 12 RNase 12 deaminase 12 ATPase 11 dipeptidyl peptidase IV 11 calcineurin 11 carboxypeptidase B 11 MEKK1 11 MAP 11 aspartate aminotransferase 11 PARP 10 more...

Compound Dec 740 serine 527 Clin 513 lysine 419 DNA 408 arginine 336 sodium 281 SDS 263 sulfate 224 acetate 221 MDA 209 Plasmin 179 PAR 164 Cardiol 147 calcium 142 tyrosine 135 Gly 125 cysteine 112 oxygen 110 Fibrin 105 alanine 103 Phe 96 methionine 91 leucine 84 cAMP 82 water 80 Heparin 78 Thrombin 76 glucose 76 NH2 75 retinoic acid 67 TNF 67 His 66 ACS 61 PMA 58 Asp 58 ASA 57 phosphate 57 PMA 55 ATF 49 zinc 49 MEK 47 urea 47 threonine 46 Fibrinogen 44 Triton X-100 40 ADP 40 ammonium 39 MTT 39 prostacyclin 38 TPA 37 TPA 37 Ile 37 salt 37 Serine 35 THP 35 THP 35 AMP 35 EDTA 35 hydrogen 35 galactose 34 ADP 34 ADP 34 PEG 33 creatinine 33 ethanol 32 EDTA 32 glutamic acid 32 6-aminohexanoic acid 30 6-aminohexanoic acid 30 DEAE 29 FDP 29 copper 29 nitric oxide 29 guanidine 26 HCl 24 PEG 23 iodine 23 Collagen 21 prostaglandin E1 21 more...

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