Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.73 (urokinase-type plasminogen activator)
 10,685 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
urokinase-type plasminogen activator 9466
plasminogen 2854
PLA 2635
urokinase plasminogen activator 1175
plasminogen activator inhibitor-1 1174
uPAR 1007
plasminogen activator inhibitor 821
Sep 717
tissue plasminogen activator 713
thrombin 606
fibrinogen 590
Plasminogen 576
u-PA 528
Mol 511
serine protease 447
matrix metalloproteinase 406
MMP-9 371
collagen 335
MMP-2 332
tPA 320
more...
Disease
cancer 1865
tumor 1689
breast cancer 562
metastases 372
carcinoma 367
acute myocardial infarction 309
tumor growth 255
tumor progression 253
SDS 246
myocardial infarction 215
stroke 212
prostate cancer 208
melanoma 199
pulmonary embolism 194
ischemia 171
deep vein thrombosis 134
adenocarcinoma 130
ovarian cancer 126
MCF 117
hepatocellular carcinoma 116
more...
Symptom
pain 68
angina 61
chest pain 58
dyspnea 28
anesthesia 27
respiratory distress 20
abdominal pain 17
seizures 15
functional recovery 15
headache 15
spasm 14
flushing 11
vomiting 11
cyanosis 10
hemiplegia 10
collapse 10
weakness 9
syncope 9
consciousness disturbance 7
hyperoxia 7
more...
Drug
uPA 1874
Urokinase 388
lysine 298
Cardiovasc 162
Dermatol 93
Streptokinase 57
CSF 44
Gel 31
DFP 28
CTA 27
Aprotinin 25
Alteplase 24
Alteplase 23
Alteplase 22
IFN-gamma 21
MAP 20
Amiloride 20
Gelatin 20
Asn 20
Amiloride 20
more...
Enzyme
urokinase-type plasminogen activator 10685
tissue plasminogen activator 2035
plasmin 2013
thrombin 590
mitogen-activated protein kinase 342
trypsin 337
ERK 246
collagenase 226
kallikrein 199
thromboplastin 150
protein kinase C 138
APC 121
MMP-3 115
MMP 107
focal adhesion kinase 105
elastase 94
chymotrypsin 94
protein kinase 91
MEK 90
matrix metalloproteinase 2 82
more...
Compound
Dec 740
serine 527
Clin 513
lysine 419
DNA 408
arginine 336
sodium 281
SDS 263
sulfate 224
acetate 221
MDA 209
Plasmin 179
PAR 164
Cardiol 147
calcium 142
tyrosine 135
Gly 125
cysteine 112
oxygen 110
Fibrin 105
more...