Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.7 (
plasmin
)
9,023
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
plasminogen
3554
urokinase-type plasminogen activator
1898
PLA
1891
thrombin
1860
fibrinogen
1514
tissue plasminogen activator
693
Plasmin
646
Sep
616
Plasminogen
549
plasminogen activator inhibitor-1
540
serine protease
507
antithrombin III
379
plasminogen activator inhibitor
365
collagen
365
kallikrein
364
prothrombin
348
SDS
309
chymotrypsin
305
fibronectin
278
Mol
277
antithrombin
269
factor Xa
220
casein
220
glycoprotein
207
matrix metalloproteinase
201
alpha 2-plasmin inhibitor
200
uPAR
193
trypsin inhibitor
186
tPA
184
urokinase plasminogen activator
179
thromboplastin
165
collagenase
163
polypeptide
155
u-PA
154
tissue factor
144
thrombomodulin
142
bradykinin
134
serine protease inhibitor
134
protein C
133
mast cell
122
MMP-9
119
von Willebrand factor
116
albumin
114
FDP
112
MMP-2
111
cathepsin G
111
vitronectin
108
cytokine
108
inhibitor-1
106
Lp(a)
101
protease inhibitor
100
PAI-2
84
insulin
84
HNE
83
neutrophil elastase
83
PAI
80
TGF-beta
80
metalloproteinase
79
annexin II
76
ADP
74
thrombin-activatable fibrinolysis inhibitor
73
Tissue plasminogen activator
73
factor XII
65
tumor necrosis factor
65
MMP-1
64
nexin
63
matrix metalloproteinase 2
62
esterase
62
vascular endothelial growth factor
62
C1 inhibitor
61
lipopolysaccharide
61
MMP-3
61
serum albumin
61
Trypsin
60
thrombin inhibitor
60
transforming growth factor-beta
60
urinary kallikrein
60
VIII
59
epidermal growth factor
58
alpha 1-antitrypsin
58
more...
Disease
cancer
539
tumor
510
SDS
309
disseminated intravascular coagulation
232
stroke
162
atherosclerosis
148
acute myocardial infarction
126
mastocytosis
115
myocardial infarction
111
diabetes
110
anaphylaxis
104
Alzheimer's disease
99
sepsis
97
metastases
94
melanoma
94
deep vein thrombosis
93
carcinoma
92
tumor growth
91
sepsis
86
breast cancer
84
tumor progression
78
coagulopathy
65
pulmonary embolism
64
cardiovascular disease
62
hypertension
61
plaque
61
ischemia
55
leukemia
54
glomerulonephritis
51
proteinuria
50
rheumatoid arthritis
49
asthma
49
coronary artery disease
43
acute promyelocytic leukemia
43
hepatocellular carcinoma
43
fibrosarcoma
41
renal disease
37
mastitis
36
nephrotic syndrome
36
cirrhosis
35
nephritis
35
arthritis
34
vascular disease
34
depression
34
uterus
32
Hereditary angioedema
32
lung cancer
32
glioma
31
Yersinia
31
infectious diseases
30
thrombocytopenia
30
squamous cell carcinoma
29
mastocytoma
29
ovarian cancer
28
diabetic nephropathy
28
systemic lupus erythematosus
28
prostate cancer
27
Thrombus
27
Mastocytosis
26
cornea
26
Systemic mastocytosis
25
adenocarcinoma
24
obesity
24
lung carcinoma
23
glomerulosclerosis
23
mole
23
urticaria
23
influenza
23
multiple myeloma
22
leptospirosis
22
cold
22
myocardial ischemia
22
tumorigenesis
22
preeclampsia
22
mole
22
type 2 diabetes
21
Lyme disease
21
cerebral ischemia
21
osteoarthritis
21
renal failure
20
more...
Symptom
anesthesia
46
pain
26
collapse
18
flushing
17
seizures
15
respiratory distress
14
angina
12
spasm
11
functional recovery
11
splenomegaly
10
dyspnea
10
headache
10
chest pain
9
diarrhea
9
vomiting
8
erythema
6
stigma
6
abdominal pain
6
hypothermia
6
cough
5
autodigestion
5
exhaustion
5
syncope
5
hepatosplenomegaly
5
nausea
5
thinning
5
dizziness
4
analgesia
4
starvation
4
Fluctuation
3
Decreased activity
3
low back pain
3
Darier's sign
3
shortness of breath
3
wheezing
3
discomfort
3
discomfort
3
HSA
3
agitation
3
oliguria
2
Welt
2
eds
2
acute abdominal pain
2
cyanosis
2
skin damage
2
acidity
2
dry skin
2
lethargy
2
acute stress
2
arthralgia
2
chills
2
rhinorrhea
2
bitter taste
2
hypoproteinemia
2
fatigue
2
Ill
2
localized edema
2
periorbital edema
2
tremor
1
photopsia
1
chest tightness
1
intestinal bleeding
1
bone pain
1
hyperoxia
1
disturbed balance
1
dry eye
1
leg pain
1
Stinging
1
hemiplegia
1
generalized rash
1
sleepiness
1
hemoptysis
1
vertigo
1
stridor
1
skin irritation
1
gumma
1
sneezing
1
dysesthesia
1
exertional angina
1
hepatomegaly
1
more...
Drug
lysine
678
uPA
358
Urokinase
101
Dermatol
101
Aprotinin
81
Cardiovasc
72
Streptokinase
65
Asn
58
Fragment
51
Gel
37
TAT
27
CTA
24
DFP
24
lactose
21
Antithrombin III
20
Asthma
18
Alteplase
16
CaCl2
16
CaCl2
16
Alteplase
16
CaCl2
16
Alteplase
14
Ancrod
13
ABC
12
Gelatin
11
Nephron
10
Nephron
10
DDAVP
9
MAP
9
PTC
9
DDAVP
9
IFN-gamma
8
Amiloride
8
ascorbate
8
Amiloride
8
Albumin
7
CSF
7
ACT
7
AMC
6
Bifidobacterium
6
L-tyrosine
6
Batimastat
6
Batimastat
6
Pronase
6
Dial
5
Monit
5
ROS
5
Activase
5
Argatroban
5
Captopril
5
Bayer
4
balanced salt solution
4
Fraction
4
PTH
4
ampicillin
4
Fluorescein
4
Angiotensin II
4
Dalteparin
4
vitamin E
4
Lovastatin
4
AHF
4
Nafamostat mesilate
3
Fluorescein
3
EE2
3
Gabexate mesilate
3
EPA
3
Doxycycline
3
Batroxobin
3
Indomethacin
3
Vitamin E
3
Hypaque
3
Guanidine
3
Guanidine
3
PE2
3
EPI
3
Hypaque
3
Vitamin B12
3
MRC
3
CPR
3
Retinoic acid
3
more...
Enzyme
plasmin
9023
urokinase-type plasminogen activator
2013
thrombin
1812
tissue plasminogen activator
1564
trypsin
1106
kallikrein
534
thromboplastin
370
chymotrypsin
351
elastase
341
APC
218
collagenase
214
neutrophil elastase
165
tryptase
138
cathepsin G
116
MMP-3
93
papain
83
ERK
78
tissue kallikrein
76
transglutaminase
71
Hageman factor
61
carboxypeptidase B
59
mitogen-activated protein kinase
57
pepsin
54
matrix metalloproteinase 2
54
cathepsin B
53
MMP
53
cathepsin D
52
enolase
51
protein kinase C
51
renin
49
thrombin-activatable fibrinolysis inhibitor
43
hyaluronidase
40
protein kinase
40
subtilisin
40
matrix metalloproteinase 9
37
peroxidase
37
CD10
32
hyaluronidase
29
furin
29
phospholipase C
28
glyceraldehyde-3-phosphate dehydrogenase
28
TAT
27
glyceraldehyde-3-phosphate dehydrogenase
27
alkaline phosphatase
26
glyceraldehyde-3-phosphate dehydrogenase
25
glyceraldehyde-3-phosphate dehydrogenase
25
glyceraldehyde-3-phosphate dehydrogenase
25
thermolysin
24
interstitial collagenase
23
neuraminidase
23
CPN
23
focal adhesion kinase
23
Pla
22
deaminase
22
chymosin
21
DNase
19
ancrod
19
catalase
19
chondroitinase
19
ACE
19
lipase
19
chondroitinase
17
phospholipase A2
17
reverse transcriptase
17
acrosin
17
matriptase
14
proteinase K
14
insulin-degrading enzyme
13
matriptase
13
beta-galactosidase
13
MEK
13
lysozyme
12
fibrolase
12
C1 esterase
12
chymase
12
lactate dehydrogenase
12
lysin
12
luciferase
12
apyrase
11
caspase-3
11
more...
Compound
lysine
956
serine
724
Dec
647
Plasmin
619
Clin
539
arginine
503
SDS
324
sulfate
308
sodium
307
calcium
273
DNA
195
Thrombin
182
Fibrin
167
leucine
166
Phe
162
alanine
155
NH2
152
Gly
142
Fibrinogen
136
cysteine
133
ACS
116
EDTA
114
FDP
112
acetate
110
EDTA
106
ADP
103
tyrosine
102
His
98
Asp
91
methionine
84
glucose
81
urea
80
oxygen
79
ADP
74
ADP
74
6-aminohexanoic acid
71
6-aminohexanoic acid
71
phosphate
71
Heparin
68
Ile
67
DEAE
66
threonine
65
water
63
zinc
61
Trypsin
60
glutamic acid
60
Tranexamic acid
59
salt
57
ammonium
54
PEG
50
Cardiol
45
DIC
44
bromide
44
creatinine
43
PAR
42
retinoic acid
42
ASA
41
PEG
38
galactose
38
MDA
38
PMSF
37
proline
34
Serine
32
nitrogen
31
PAP
31
PAP
31
PAP
31
PAP
31
Triton X-100
31
TNF
30
ethanol
30
THP
29
TEM
29
nitric oxide
29
THP
29
HCl
29
copper
28
Collagen
28
hydrogen
28
acrylamide
28
more...