Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.7 (plasmin)
9,023 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
plasminogen 3554
urokinase-type plasminogen activator 1898
PLA 1891
thrombin 1860
fibrinogen 1514
tissue plasminogen activator 693
Plasmin 646
Sep 616
Plasminogen 549
plasminogen activator inhibitor-1 540
serine protease 507
antithrombin III 379
plasminogen activator inhibitor 365
collagen 365
kallikrein 364
prothrombin 348
SDS 309
chymotrypsin 305
fibronectin 278
Mol 277
antithrombin 269
factor Xa 220
casein 220
glycoprotein 207
matrix metalloproteinase 201
alpha 2-plasmin inhibitor 200
uPAR 193
trypsin inhibitor 186
tPA 184
urokinase plasminogen activator 179
thromboplastin 165
collagenase 163
polypeptide 155
u-PA 154
tissue factor 144
thrombomodulin 142
bradykinin 134
serine protease inhibitor 134
protein C 133
mast cell 122
MMP-9 119
von Willebrand factor 116
albumin 114
FDP 112
MMP-2 111
cathepsin G 111
vitronectin 108
cytokine 108
inhibitor-1 106
Lp(a) 101
protease inhibitor 100
PAI-2 84
insulin 84
HNE 83
neutrophil elastase 83
PAI 80
TGF-beta 80
metalloproteinase 79
annexin II 76
ADP 74
thrombin-activatable fibrinolysis inhibitor 73
Tissue plasminogen activator 73
factor XII 65
tumor necrosis factor 65
MMP-1 64
nexin 63
matrix metalloproteinase 2 62
esterase 62
vascular endothelial growth factor 62
C1 inhibitor 61
lipopolysaccharide 61
MMP-3 61
serum albumin 61
Trypsin 60
thrombin inhibitor 60
transforming growth factor-beta 60
urinary kallikrein 60
VIII 59
epidermal growth factor 58
alpha 1-antitrypsin 58
more...
Disease
cancer 539
tumor 510
SDS 309
disseminated intravascular coagulation 232
stroke 162
atherosclerosis 148
acute myocardial infarction 126
mastocytosis 115
myocardial infarction 111
diabetes 110
anaphylaxis 104
Alzheimer's disease 99
sepsis 97
metastases 94
melanoma 94
deep vein thrombosis 93
carcinoma 92
tumor growth 91
sepsis 86
breast cancer 84
tumor progression 78
coagulopathy 65
pulmonary embolism 64
cardiovascular disease 62
hypertension 61
plaque 61
ischemia 55
leukemia 54
glomerulonephritis 51
proteinuria 50
rheumatoid arthritis 49
asthma 49
coronary artery disease 43
acute promyelocytic leukemia 43
hepatocellular carcinoma 43
fibrosarcoma 41
renal disease 37
mastitis 36
nephrotic syndrome 36
cirrhosis 35
nephritis 35
arthritis 34
vascular disease 34
depression 34
uterus 32
Hereditary angioedema 32
lung cancer 32
glioma 31
Yersinia 31
infectious diseases 30
thrombocytopenia 30
squamous cell carcinoma 29
mastocytoma 29
ovarian cancer 28
diabetic nephropathy 28
systemic lupus erythematosus 28
prostate cancer 27
Thrombus 27
Mastocytosis 26
cornea 26
Systemic mastocytosis 25
adenocarcinoma 24
obesity 24
lung carcinoma 23
glomerulosclerosis 23
mole 23
urticaria 23
influenza 23
multiple myeloma 22
leptospirosis 22
cold 22
myocardial ischemia 22
tumorigenesis 22
preeclampsia 22
mole 22
type 2 diabetes 21
Lyme disease 21
cerebral ischemia 21
osteoarthritis 21
renal failure 20
more...
Symptom
anesthesia 46
pain 26
collapse 18
flushing 17
seizures 15
respiratory distress 14
angina 12
spasm 11
functional recovery 11
splenomegaly 10
dyspnea 10
headache 10
chest pain 9
diarrhea 9
vomiting 8
erythema 6
stigma 6
abdominal pain 6
hypothermia 6
cough 5
autodigestion 5
exhaustion 5
syncope 5
hepatosplenomegaly 5
nausea 5
thinning 5
dizziness 4
analgesia 4
starvation 4
Fluctuation 3
Decreased activity 3
low back pain 3
Darier's sign 3
shortness of breath 3
wheezing 3
discomfort 3
discomfort 3
HSA 3
agitation 3
oliguria 2
Welt 2
eds 2
acute abdominal pain 2
cyanosis 2
skin damage 2
acidity 2
dry skin 2
lethargy 2
acute stress 2
arthralgia 2
chills 2
rhinorrhea 2
bitter taste 2
hypoproteinemia 2
fatigue 2
Ill 2
localized edema 2
periorbital edema 2
tremor 1
photopsia 1
chest tightness 1
intestinal bleeding 1
bone pain 1
hyperoxia 1
disturbed balance 1
dry eye 1
leg pain 1
Stinging 1
hemiplegia 1
generalized rash 1
sleepiness 1
hemoptysis 1
vertigo 1
stridor 1
skin irritation 1
gumma 1
sneezing 1
dysesthesia 1
exertional angina 1
hepatomegaly 1
more...
Drug
lysine 678
uPA 358
Urokinase 101
Dermatol 101
Aprotinin 81
Cardiovasc 72
Streptokinase 65
Asn 58
Fragment 51
Gel 37
TAT 27
CTA 24
DFP 24
lactose 21
Antithrombin III 20
Asthma 18
Alteplase 16
CaCl2 16
CaCl2 16
Alteplase 16
CaCl2 16
Alteplase 14
Ancrod 13
ABC 12
Gelatin 11
Nephron 10
Nephron 10
DDAVP 9
MAP 9
PTC 9
DDAVP 9
IFN-gamma 8
Amiloride 8
ascorbate 8
Amiloride 8
Albumin 7
CSF 7
ACT 7
AMC 6
Bifidobacterium 6
L-tyrosine 6
Batimastat 6
Batimastat 6
Pronase 6
Dial 5
Monit 5
ROS 5
Activase 5
Argatroban 5
Captopril 5
Bayer 4
balanced salt solution 4
Fraction 4
PTH 4
ampicillin 4
Fluorescein 4
Angiotensin II 4
Dalteparin 4
vitamin E 4
Lovastatin 4
AHF 4
Nafamostat mesilate 3
Fluorescein 3
EE2 3
Gabexate mesilate 3
EPA 3
Doxycycline 3
Batroxobin 3
Indomethacin 3
Vitamin E 3
Hypaque 3
Guanidine 3
Guanidine 3
PE2 3
EPI 3
Hypaque 3
Vitamin B12 3
MRC 3
CPR 3
Retinoic acid 3
more...
Enzyme
plasmin 9023
urokinase-type plasminogen activator 2013
thrombin 1812
tissue plasminogen activator 1564
trypsin 1106
kallikrein 534
thromboplastin 370
chymotrypsin 351
elastase 341
APC 218
collagenase 214
neutrophil elastase 165
tryptase 138
cathepsin G 116
MMP-3 93
papain 83
ERK 78
tissue kallikrein 76
transglutaminase 71
Hageman factor 61
carboxypeptidase B 59
mitogen-activated protein kinase 57
pepsin 54
matrix metalloproteinase 2 54
cathepsin B 53
MMP 53
cathepsin D 52
enolase 51
protein kinase C 51
renin 49
thrombin-activatable fibrinolysis inhibitor 43
hyaluronidase 40
protein kinase 40
subtilisin 40
matrix metalloproteinase 9 37
peroxidase 37
CD10 32
hyaluronidase 29
furin 29
phospholipase C 28
glyceraldehyde-3-phosphate dehydrogenase 28
TAT 27
glyceraldehyde-3-phosphate dehydrogenase 27
alkaline phosphatase 26
glyceraldehyde-3-phosphate dehydrogenase 25
glyceraldehyde-3-phosphate dehydrogenase 25
glyceraldehyde-3-phosphate dehydrogenase 25
thermolysin 24
interstitial collagenase 23
neuraminidase 23
CPN 23
focal adhesion kinase 23
Pla 22
deaminase 22
chymosin 21
DNase 19
ancrod 19
catalase 19
chondroitinase 19
ACE 19
lipase 19
chondroitinase 17
phospholipase A2 17
reverse transcriptase 17
acrosin 17
matriptase 14
proteinase K 14
insulin-degrading enzyme 13
matriptase 13
beta-galactosidase 13
MEK 13
lysozyme 12
fibrolase 12
C1 esterase 12
chymase 12
lactate dehydrogenase 12
lysin 12
luciferase 12
apyrase 11
caspase-3 11
more...
Compound
lysine 956
serine 724
Dec 647
Plasmin 619
Clin 539
arginine 503
SDS 324
sulfate 308
sodium 307
calcium 273
DNA 195
Thrombin 182
Fibrin 167
leucine 166
Phe 162
alanine 155
NH2 152
Gly 142
Fibrinogen 136
cysteine 133
ACS 116
EDTA 114
FDP 112
acetate 110
EDTA 106
ADP 103
tyrosine 102
His 98
Asp 91
methionine 84
glucose 81
urea 80
oxygen 79
ADP 74
ADP 74
6-aminohexanoic acid 71
6-aminohexanoic acid 71
phosphate 71
Heparin 68
Ile 67
DEAE 66
threonine 65
water 63
zinc 61
Trypsin 60
glutamic acid 60
Tranexamic acid 59
salt 57
ammonium 54
PEG 50
Cardiol 45
DIC 44
bromide 44
creatinine 43
PAR 42
retinoic acid 42
ASA 41
PEG 38
galactose 38
MDA 38
PMSF 37
proline 34
Serine 32
nitrogen 31
PAP 31
PAP 31
PAP 31
PAP 31
Triton X-100 31
TNF 30
ethanol 30
THP 29
TEM 29
nitric oxide 29
THP 29
HCl 29
copper 28
Collagen 28
hydrogen 28
acrylamide 28
more...