Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.7 (
plasmin
)
9,023
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
plasminogen
3554
urokinase-type plasminogen activator
1898
PLA
1891
thrombin
1860
fibrinogen
1514
tissue plasminogen activator
693
Plasmin
646
Sep
616
Plasminogen
549
plasminogen activator inhibitor-1
540
serine protease
507
antithrombin III
379
plasminogen activator inhibitor
365
collagen
365
kallikrein
364
prothrombin
348
SDS
309
chymotrypsin
305
fibronectin
278
Mol
277
antithrombin
269
casein
220
factor Xa
220
glycoprotein
207
matrix metalloproteinase
201
alpha 2-plasmin inhibitor
200
uPAR
193
trypsin inhibitor
186
tPA
184
urokinase plasminogen activator
179
thromboplastin
165
collagenase
163
polypeptide
155
u-PA
154
tissue factor
144
thrombomodulin
142
bradykinin
134
serine protease inhibitor
134
protein C
133
mast cell
122
more...
Disease
cancer
539
tumor
510
SDS
309
disseminated intravascular coagulation
232
stroke
162
atherosclerosis
148
acute myocardial infarction
126
mastocytosis
115
myocardial infarction
111
diabetes
110
anaphylaxis
104
Alzheimer's disease
99
sepsis
97
melanoma
94
metastases
94
deep vein thrombosis
93
carcinoma
92
tumor growth
91
sepsis
86
breast cancer
84
tumor progression
78
coagulopathy
65
pulmonary embolism
64
cardiovascular disease
62
plaque
61
hypertension
61
ischemia
55
leukemia
54
glomerulonephritis
51
proteinuria
50
rheumatoid arthritis
49
asthma
49
acute promyelocytic leukemia
43
coronary artery disease
43
hepatocellular carcinoma
43
fibrosarcoma
41
renal disease
37
mastitis
36
nephrotic syndrome
36
cirrhosis
35
more...
Symptom
anesthesia
46
pain
26
collapse
18
flushing
17
seizures
15
respiratory distress
14
angina
12
spasm
11
functional recovery
11
splenomegaly
10
dyspnea
10
headache
10
chest pain
9
diarrhea
9
vomiting
8
stigma
6
abdominal pain
6
hypothermia
6
erythema
6
nausea
5
exhaustion
5
autodigestion
5
syncope
5
cough
5
thinning
5
hepatosplenomegaly
5
starvation
4
analgesia
4
dizziness
4
discomfort
3
Fluctuation
3
agitation
3
shortness of breath
3
wheezing
3
low back pain
3
Decreased activity
3
discomfort
3
Darier's sign
3
HSA
3
eds
2
more...
Drug
lysine
678
uPA
358
Urokinase
101
Dermatol
101
Aprotinin
81
Cardiovasc
72
Streptokinase
65
Asn
58
Fragment
51
Gel
37
TAT
27
CTA
24
DFP
24
lactose
21
Antithrombin III
20
Asthma
18
CaCl2
16
CaCl2
16
Alteplase
16
CaCl2
16
Alteplase
16
Alteplase
14
Ancrod
13
ABC
12
Gelatin
11
Nephron
10
Nephron
10
DDAVP
9
DDAVP
9
PTC
9
MAP
9
Amiloride
8
Amiloride
8
IFN-gamma
8
ascorbate
8
ACT
7
CSF
7
Albumin
7
Batimastat
6
Bifidobacterium
6
more...
Enzyme
plasmin
9023
urokinase-type plasminogen activator
2013
thrombin
1812
tissue plasminogen activator
1564
trypsin
1106
kallikrein
534
thromboplastin
370
chymotrypsin
351
elastase
341
APC
218
collagenase
214
neutrophil elastase
165
tryptase
138
cathepsin G
116
MMP-3
93
papain
83
ERK
78
tissue kallikrein
76
transglutaminase
71
Hageman factor
61
carboxypeptidase B
59
mitogen-activated protein kinase
57
pepsin
54
matrix metalloproteinase 2
54
cathepsin B
53
MMP
53
cathepsin D
52
enolase
51
protein kinase C
51
renin
49
thrombin-activatable fibrinolysis inhibitor
43
protein kinase
40
hyaluronidase
40
subtilisin
40
peroxidase
37
matrix metalloproteinase 9
37
CD10
32
hyaluronidase
29
furin
29
glyceraldehyde-3-phosphate dehydrogenase
28
more...
Compound
lysine
956
serine
724
Dec
647
Plasmin
619
Clin
539
arginine
503
SDS
324
sulfate
308
sodium
307
calcium
273
DNA
195
Thrombin
182
Fibrin
167
leucine
166
Phe
162
alanine
155
NH2
152
Gly
142
Fibrinogen
136
cysteine
133
ACS
116
EDTA
114
FDP
112
acetate
110
EDTA
106
ADP
103
tyrosine
102
His
98
Asp
91
methionine
84
glucose
81
urea
80
oxygen
79
ADP
74
ADP
74
6-aminohexanoic acid
71
6-aminohexanoic acid
71
phosphate
71
Heparin
68
Ile
67
more...