Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.7 (plasmin)
9,023 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
plasminogen 3554
urokinase-type plasminogen activator 1898
PLA 1891
thrombin 1860
fibrinogen 1514
tissue plasminogen activator 693
Plasmin 646
Sep 616
Plasminogen 549
plasminogen activator inhibitor-1 540
serine protease 507
antithrombin III 379
plasminogen activator inhibitor 365
collagen 365
kallikrein 364
prothrombin 348
SDS 309
chymotrypsin 305
fibronectin 278
Mol 277
antithrombin 269
casein 220
factor Xa 220
glycoprotein 207
matrix metalloproteinase 201
alpha 2-plasmin inhibitor 200
uPAR 193
trypsin inhibitor 186
tPA 184
urokinase plasminogen activator 179
thromboplastin 165
collagenase 163
polypeptide 155
u-PA 154
tissue factor 144
thrombomodulin 142
bradykinin 134
serine protease inhibitor 134
protein C 133
mast cell 122
more...
Disease
cancer 539
tumor 510
SDS 309
disseminated intravascular coagulation 232
stroke 162
atherosclerosis 148
acute myocardial infarction 126
mastocytosis 115
myocardial infarction 111
diabetes 110
anaphylaxis 104
Alzheimer's disease 99
sepsis 97
melanoma 94
metastases 94
deep vein thrombosis 93
carcinoma 92
tumor growth 91
sepsis 86
breast cancer 84
tumor progression 78
coagulopathy 65
pulmonary embolism 64
cardiovascular disease 62
plaque 61
hypertension 61
ischemia 55
leukemia 54
glomerulonephritis 51
proteinuria 50
rheumatoid arthritis 49
asthma 49
acute promyelocytic leukemia 43
coronary artery disease 43
hepatocellular carcinoma 43
fibrosarcoma 41
renal disease 37
mastitis 36
nephrotic syndrome 36
cirrhosis 35
more...
Symptom
anesthesia 46
pain 26
collapse 18
flushing 17
seizures 15
respiratory distress 14
angina 12
spasm 11
functional recovery 11
splenomegaly 10
dyspnea 10
headache 10
chest pain 9
diarrhea 9
vomiting 8
stigma 6
abdominal pain 6
hypothermia 6
erythema 6
nausea 5
exhaustion 5
autodigestion 5
syncope 5
cough 5
thinning 5
hepatosplenomegaly 5
starvation 4
analgesia 4
dizziness 4
discomfort 3
Fluctuation 3
agitation 3
shortness of breath 3
wheezing 3
low back pain 3
Decreased activity 3
discomfort 3
Darier's sign 3
HSA 3
eds 2
more...
Drug
lysine 678
uPA 358
Urokinase 101
Dermatol 101
Aprotinin 81
Cardiovasc 72
Streptokinase 65
Asn 58
Fragment 51
Gel 37
TAT 27
CTA 24
DFP 24
lactose 21
Antithrombin III 20
Asthma 18
CaCl2 16
CaCl2 16
Alteplase 16
CaCl2 16
Alteplase 16
Alteplase 14
Ancrod 13
ABC 12
Gelatin 11
Nephron 10
Nephron 10
DDAVP 9
DDAVP 9
PTC 9
MAP 9
Amiloride 8
Amiloride 8
IFN-gamma 8
ascorbate 8
ACT 7
CSF 7
Albumin 7
Batimastat 6
Bifidobacterium 6
more...
Enzyme
plasmin 9023
urokinase-type plasminogen activator 2013
thrombin 1812
tissue plasminogen activator 1564
trypsin 1106
kallikrein 534
thromboplastin 370
chymotrypsin 351
elastase 341
APC 218
collagenase 214
neutrophil elastase 165
tryptase 138
cathepsin G 116
MMP-3 93
papain 83
ERK 78
tissue kallikrein 76
transglutaminase 71
Hageman factor 61
carboxypeptidase B 59
mitogen-activated protein kinase 57
pepsin 54
matrix metalloproteinase 2 54
cathepsin B 53
MMP 53
cathepsin D 52
enolase 51
protein kinase C 51
renin 49
thrombin-activatable fibrinolysis inhibitor 43
protein kinase 40
hyaluronidase 40
subtilisin 40
peroxidase 37
matrix metalloproteinase 9 37
CD10 32
hyaluronidase 29
furin 29
glyceraldehyde-3-phosphate dehydrogenase 28
more...
Compound
lysine 956
serine 724
Dec 647
Plasmin 619
Clin 539
arginine 503
SDS 324
sulfate 308
sodium 307
calcium 273
DNA 195
Thrombin 182
Fibrin 167
leucine 166
Phe 162
alanine 155
NH2 152
Gly 142
Fibrinogen 136
cysteine 133
ACS 116
EDTA 114
FDP 112
acetate 110
EDTA 106
ADP 103
tyrosine 102
His 98
Asp 91
methionine 84
glucose 81
urea 80
oxygen 79
ADP 74
ADP 74
6-aminohexanoic acid 71
6-aminohexanoic acid 71
phosphate 71
Heparin 68
Ile 67
more...