Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.7 (
plasmin
)
9,023
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The article presents results of study concerning biochemical markers of endothelial dysfunction and structural changes in cardiovascular system of aluminium production workers with initial and advanced symptoms of occupationally related bronchopulmonary diseases. Common pathogenetic traits of cardiovascular diseases with initial and advanced symptoms of occupationally related bronchopulmonary diseases are disordered regulation of vascular tone due to
nitrogen
and
plasmin
, atherosclerotic plaques formation and changed cardiomyocytes function. Individuals with initial symptoms of occupationally related bronchopulmonary diseases are characterized by increased cardiomyocytes apoptosis due to circulatory disorders. Mechanisms of cardiovascular diseases for advanced symptoms of occupationally related bronchopulmonary diseases are related to disordered regulation of cellular hemostasis by
nitrogen
oxide and
plasmin
, changed regulation via b-adrenoreceptors and altered cardiomyocytes metabolism.
...
PMID:[Biochemical markers of endothelial dysfunction and cardiovascular system state in patients with occupationai bronchopulmonary diseases]. 3035 51
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