Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.7 (
plasmin
)
9,023
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Using two models of experimental thrombosis (arterio-venous shunt and Wessler's model) the effect of
plasmin
and its combination with alpha-adrenoreceptor antagonists on the formation of thrombus was studied on white rats. It was established that the efficacy of prophylactic of thrombosis by
plasmin
only was low: middle ball of thrombosis was 2.5-3.0. The combination of
plasmin
with alpha-adrenoblockers dihydroergotoxine or prazosin under these conditions is most efficient against the formation of thrombus (middle ball of thrombus in this case was 0.8-1.1).
Prazosin
under certain conditions have some advantages.
...
PMID:[Thrombosis prophylaxis using plasmin and its combination with alpha-adrenoreceptor antagonists]. 136 12
