Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.69 (APC)
16,337 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
APC 0.492
protein C 0.387
protein S 0.065
Protein C 0.056
anaphase-promoting complex/cyclosome 0.022
thrombomodulin 0.019
factor V Leiden 0.016
factor V 0.015
antithrombin 0.013
antithrombin III 0.012
endothelial protein C receptor 0.008
Protein S 0.008
thrombin 0.008
prothrombin 0.007
Thrombomodulin 0.007
plasma protein C 0.005
securin 0.003
KEN 0.002
tissue factor pathway inhibitor 0.002
CTNNB1 0.002
fibrinogen 0.002
tissue factor 0.002
APC protein 0.002
thromboplastin 0.002
factor Xa 0.002
beta-catenin 0.001
type I protein C 0.001
adenomatous polyposis coli 0.001
coagulation factor V 0.001
factor VII 0.001
EPCR 0.001
plasminogen 0.001
FZR1 0.001
Mad2 0.001
TCR 0.001
MUTYH 0.001
factor VIII 0.001
ubiquitin ligase 0.001
RASSF1A 0.001
CDH1 0.001
heparin cofactor II 0.001
PCI 0.001
C4b-binding protein 0.001
plasminogen activator inhibitor 0.001
KRAS 0.001
MHC class II 0.001
DCC 0.001
tumor suppressor APC 0.001
CDC20 0.001
MHC 0.001
APC3 0.001
Axin 0.001
Antithrombin III 0.001
protein Z 0.001
APC8 0.001
plasminogen activator inhibitor-1 0.001
MYH 0.001
early mitotic inhibitor 1 0.001
MCC 0.001
VIII 0.001
SMAD4 0.001
AXIN1 0.001
factor IX 0.001
Prothrombin 0.001
tissue plasminogen activator 0.001
p53 0.001
catenin 0.001
Antithrombin 0.000
MLH1 0.000
AXIN 0.000
TM mRNA 0.000
AXIN2 0.000
von Willebrand factor 0.000
vitamin K-dependent protein S 0.000
serine protease 0.000
hMLH1 0.000
APC2 0.000
DAPK 0.000
SFRP1 0.000
K-ras 0.000
more...
Disease
APC 0.387
PC deficiency 0.006
familial adenomatous polyposis 0.006
Activated protein C resistance 0.003
Protein C deficiency 0.003
hereditary protein C deficiency 0.001
Thrombophilia 0.001
disseminated intravascular coagulation 0.001
Factor V Leiden mutation 0.001
colorectal cancer 0.001
polyposis 0.001
Severe sepsis 0.001
deep vein thrombosis 0.001
Purpura fulminans 0.001
sepsis 0.001
lupus 0.001
sepsis 0.000
lupus 0.000
Protein S deficiency 0.000
coagulopathy 0.000
HPC4 0.000
antiphospholipid syndrome 0.000
purpura 0.000
MYH-associated polyposis 0.000
dysfibrinogenemia 0.000
hyperhomocysteinemia 0.000
tumor 0.000
Antithrombin deficiency 0.000
desmoid 0.000
systemic lupus erythematosus 0.000
cancer 0.000
colon cancer 0.000
tumorigenesis 0.000
adenoma 0.000
Lynch syndrome 0.000
carcinogenesis 0.000
Merkel cell carcinoma 0.000
HNPCC 0.000
Turcot syndrome 0.000
pulmonary embolism 0.000
Gardner's syndrome 0.000
AAPC 0.000
Sepsis with acute organ dysfunction 0.000
Acute coagulopathy 0.000
Lyme disease 0.000
Duodenal polyposis 0.000
Factor II mutation 0.000
Portal vein thrombosis 0.000
Acquired hypoprothrombinemia 0.000
Omental gangrene 0.000
MLVI2 0.000
mesenteric thrombosis 0.000
vitamin K deficiency 0.000
Coumarin necrosis 0.000
hypertrophic cardiomyopathy 0.000
superficial thrombophlebitis 0.000
carcinoma 0.000
Serrated adenoma 0.000
Neonatal thrombocytopenia 0.000
Cerebral venous thrombosis 0.000
Duodenal mass 0.000
Noninfective endocarditis 0.000
Budd-Chiari syndrome 0.000
Thrombus 0.000
Familial Hypertrophic Cardiomyopathy 0.000
circulating anticoagulants 0.000
cerebral thrombosis 0.000
clotting factor deficiency 0.000
Hypertrophic cardiomyopathy 0.000
meningococcemia 0.000
adenocarcinoma 0.000
DVT 0.000
familial cancer 0.000
Peutz-Jeghers syndrome 0.000
VKCFD1 0.000
Disorders of mitochondrial metabolism 0.000
stroke 0.000
veno-occlusive disease 0.000
thrombocytopenia 0.000
tumor progression 0.000
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Symptom
Livedoid 0.000
Unexplained abdominal pain 0.000
Intermittent fever 0.000
livedo 0.000
respiratory distress 0.000
leg edema 0.000
abdominal pain 0.000
Organ failure 0.000
anal pain 0.000
hypothermia 0.000
left upper quadrant pain 0.000
erythema 0.000
splenomegaly 0.000
headache 0.000
chest pain 0.000
Flare 0.000
peri-menopausal 0.000
Neurologic symptoms 0.000
starvation 0.000
impaired motor coordination 0.000
hemiplegia 0.000
angina 0.000
pedal edema 0.000
dyspnea 0.000
seizures 0.000
functional recovery 0.000
exhaustion 0.000
HSA 0.000
Fluctuation 0.000
tachypnea 0.000
collapse 0.000
pain 0.000
hyperemesis 0.000
right upper quadrant pain 0.000
dysarthria 0.000
right lower quadrant pain 0.000
vomiting 0.000
chills 0.000
intestinal bleeding 0.000
anesthesia 0.000
hypotonia 0.000
eye pain 0.000
epigastric pain 0.000
mastalgia 0.000
DNA marker 0.000
shortness of breath 0.000
hyperoxia 0.000
neuralgia 0.000
Spots 0.000
hepatomegaly 0.000
diarrhea 0.000
paresis 0.000
hypoproteinemia 0.000
syncopal episodes 0.000
colic 0.000
leg pain 0.000
weakness 0.000
clumsiness 0.000
presyncope 0.000
neck stiffness 0.000
pallor 0.000
lethargy 0.000
hepatosplenomegaly 0.000
overweight 0.000
exertional angina 0.000
chest tightness 0.000
acute abdomen 0.000
acute abdominal pain 0.000
chorea 0.000
nausea 0.000
cyanosis 0.000
dysesthesia 0.000
hemoptysis 0.000
facial pain 0.000
emaciation 0.000
hot flashes 0.000
abnormal gait 0.000
decreased appetite 0.000
asthenia 0.000
muscle stiffness 0.000
more...
Drug
Drotrecogin alfa 0.002
Drotrecogin alfa 0.002
Antithrombin III 0.001
IFN-gamma 0.000
IL-2 0.000
Edodekin alfa 0.000
Selodenoson 0.000
Efaproxiral sodium 0.000
Ximelagatran 0.000
PTC 0.000
Vitamin K 0.000
Zofenopril calcium 0.000
Motexafin lutetium 0.000
Holin 0.000
Valdecoxib 0.000
APD-356 0.000
Percodan 0.000
Irinotecan 0.000
TAT 0.000
Gemifloxacin mesylate 0.000
Coumadin 0.000
Desmoteplase 0.000
Zanolimumab 0.000
CPT-11 0.000
Parecoxib sodium 0.000
CSF 0.000
L-Asparaginase 0.000
Provenge 0.000
Fosamprenavir calcium 0.000
Z-Pro-Prolinal 0.000
Ancrod 0.000
Valcyte 0.000
Kifunensine 0.000
Percocet 0.000
Zomepirac sodium 0.000
OP-2 0.000
Hemolink 0.000
Warfarin sodium 0.000
Vitamin B12 0.000
Bextra 0.000
Asn 0.000
Ziprasidone hydrochloride 0.000
Phenprocoumon 0.000
PT-141 0.000
Ecallantide 0.000
uPA 0.000
Mononine 0.000
Antihemophilic factor 0.000
Dextran sulfate sodium 0.000
Fragmin 0.000
Betamethasone dipropionate 0.000
CIA 0.000
Nesiritide 0.000
Orgaran 0.000
Vioxx 0.000
Fondaparinux 0.000
Palonosetron hydrochloride 0.000
Cangrelor 0.000
lysine 0.000
Kaolin 0.000
THF 0.000
LMWH 0.000
Aprotinin 0.000
fluphenazine dihydrochloride 0.000
Eszopiclone 0.000
CaCl2 0.000
CaCl2 0.000
Clemastine 0.000
CaCl2 0.000
Abatacept 0.000
Sivelestat 0.000
Copaxone 0.000
Efalizumab 0.000
Intron A 0.000
Efalizumab 0.000
CS-514 0.000
Beraprost 0.000
Frovatriptan 0.000
Argatroban 0.000
Genasense 0.000
more...
Enzyme
APC 1.000
thrombin 0.007
thromboplastin 0.003
tissue plasminogen activator 0.001
separase 0.000
thrombin-activatable fibrinolysis inhibitor 0.000
plasmin 0.000
STK11 0.000
methylenetetrahydrofolate reductase 0.000
methylenetetrahydrofolate reductase 0.000
polo-like kinase 1 0.000
proteasome 0.000
urokinase-type plasminogen activator 0.000
choline-sulfatase 0.000
glycine reductase 0.000
sarcosine reductase 0.000
ERK 0.000
kallikrein 0.000
duodenase 0.000
EC 5.4.99.15 0.000
cdc2 0.000
protein kinase 0.000
GSK 0.000
ubiquitin-protein ligase 0.000
TAT 0.000
mitogen-activated protein kinase 0.000
trypsin 0.000
asparaginase 0.000
succinyl-diaminopimelate desuccinylase 0.000
RVV-V 0.000
cancer procoagulant 0.000
histidinol phosphate aminotransferase 0.000
C1 esterase 0.000
chymotrypsin 0.000
phycocyanobilin:ferredoxin oxidoreductase 0.000
focal adhesion kinase 0.000
carboxypeptidase B 0.000
TSR 0.000
bacillolysin 0.000
neutrophil elastase 0.000
vibriolysin 0.000
dichloromethane dehalogenase 0.000
aminopeptidase Y 0.000
tryptase 0.000
lysozyme 0.000
cystathionine beta-synthase 0.000
granzyme M 0.000
Hageman factor 0.000
granzyme B 0.000
calcineurin 0.000
neurosin 0.000
CPN 0.000
cathepsin G 0.000
factor C 0.000
coagulation factor XIa 0.000
protein kinase C 0.000
acetylornithinase 0.000
elastase 0.000
fibrolase 0.000
CGT 0.000
MEK 0.000
SPC 0.000
cathepsin S 0.000
ancrod 0.000
TGT 0.000
tripeptidase 0.000
tissue kallikrein 0.000
dolichol kinase 0.000
Delta6-desaturase 0.000
RNA polymerase 0.000
hepsin 0.000
hepsin 0.000
deoxyhypusine hydroxylase 0.000
MHCK 0.000
BMT 0.000
carboxypeptidase S 0.000
PNGase F 0.000
caspase-5 0.000
ethanolamine ammonia-lyase 0.000
clotting enzyme 0.000
more...
Compound
Thrombin 0.001
DCC 0.000
5-aminopentanoic acid 0.000
FAP 0.000
FAP 0.000
Factor X 0.000
DNA 0.000
Fibrinogen 0.000
arginine 0.000
Warfarin 0.000
homocysteine 0.000
Vitamin K 0.000
DIC 0.000
C8H9N3O3 0.000
1H-imidazo[4,5-b]pyrazine 0.000
C7H14O 0.000
Heparin 0.000
FDP 0.000
SN-38 0.000
serine 0.000
Aspidospermine 0.000
3H-[1,2,3]triazolo[4,5-b]pyridine 0.000
Aspidospermine 0.000
calcium 0.000
[1,2,4]triazolo[4,3-a]pyrazine 0.000
Dec 0.000
[1,2,4]triazolo[4,3-a]pyrimidine 0.000
Clin 0.000
PCI 0.000
[1,2,4]triazolo[4,3-c]pyrimidine 0.000
NKT 0.000
lysine 0.000
prostacyclin 0.000
CPT-11 0.000
alanine 0.000
TNF 0.000
Asp 0.000
Nelfinavir mesylate 0.000
PMA 0.000
Genkwanin 0.000
threonine 0.000
Gly 0.000
Sulindac 0.000
sulfate 0.000
Paraformaldehyde 0.000
Fibrin 0.000
tyrosine 0.000
Ailanthone 0.000
SDS 0.000
Coumarin 0.000
Homocysteine 0.000
Homocysteine 0.000
PMA 0.000
methionine 0.000
Microcephalin 0.000
Amarogentin 0.000
Ailanthone 0.000
glutamine 0.000
Paraformaldehyde 0.000
His 0.000
Ubiquitin 0.000
E09 0.000
2-chlorobenzaldehyde 0.000
E09 0.000
cysteine 0.000
M 14 0.000
leucine 0.000
Plasmin 0.000
sodium 0.000
Benzamidine 0.000
S.T.D. 0.000
TAP 0.000
Fibrinopeptide A 0.000
Neohesperidin 0.000
ETH 0.000
Cbl 0.000
Caprolactam 0.000
K 10 0.000
2,5-piperazinedione 0.000
Stearidonic acid 0.000
more...