Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.69 (APC)
16,337 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein APC 8035 protein C 6318 thrombin 2049 protein S 2009 prothrombin 1274 Sep 1100 antithrombin 1029 antithrombin III 1022 thrombomodulin 946 Protein C 918 fibrinogen 917 p53 807 factor V 705 Mol 704 factor V Leiden 677 CD4 613 cytokine 539 TCR 519 MHC 495 thromboplastin 473 anaphase-promoting complex/cyclosome 451 beta-catenin 447 plasminogen 432 tissue factor 405 IFN-gamma 405 factor VIII 403 catenin 394 IL-2 380 CD8 377 factor Xa 360 MHC class II 357 ubiquitin 328 ubiquitin ligase 302 KRAS 302 Protein S 288 VIII 272 von Willebrand factor 259 serine protease 257 plasminogen activator inhibitor-1 248 IL-10 248 factor VII 248 PLA 248 cyclin 244 IL-4 244 plasminogen activator inhibitor 242 Thrombomodulin 236 tissue plasminogen activator 230 myosin 225 CD28 221 adenomatous polyposis coli 206 endothelial protein C receptor 205 proteasome 200 glycoprotein 199 CTNNB1 196 IL-6 194 tissue factor pathway inhibitor 188 BRAF 180 PCI 176 E3 ubiquitin ligase 173 CD40 171 E-cadherin 169 MHC class I 168 LPS 159 p16 158 CD86 156 CDH1 153 insulin 153 lymphoid 150 TNF-alpha 149 factor IX 146 CD80 145 securin 143 tumor necrosis factor 143 HLA 142 heavy chain 137 PTEN 136 TNF 135 MLH1 134 epidermal growth factor 133 C4b-binding protein 132 more...

Disease APC 8035 cancer 2198 tumor 1837 colorectal cancer 930 sepsis 683 sepsis 672 familial adenomatous polyposis 630 carcinogenesis 495 tumorigenesis 478 systemic lupus erythematosus 452 carcinoma 412 lupus 406 disseminated intravascular coagulation 394 deep vein thrombosis 393 lupus 362 colon cancer 348 stroke 312 adenoma 289 polyposis 282 coagulopathy 231 adenocarcinoma 225 pulmonary embolism 209 diabetes 197 breast cancer 179 antiphospholipid syndrome 166 purpura 166 tumor progression 156 myocardial infarction 144 ischemia 143 atherosclerosis 142 metastases 137 thrombocytopenia 135 tumor growth 132 hyperhomocysteinemia 126 PC deficiency 125 dysplasia 115 HIV 115 gastric cancer 114 Thrombophilia 111 hypertension 109 hepatocellular carcinoma 108 Lyme disease 108 SDS 100 cirrhosis 100 Merkel cell carcinoma 97 influenza 91 Lynch syndrome 90 hypertrophic cardiomyopathy 90 desmoid 89 leukemia 89 preeclampsia 86 obesity 86 melanoma 86 lung cancer 85 ATM 83 virus infection 79 encephalomyelitis 78 prostate cancer 77 lymphoma 75 infectious diseases 72 autoimmune disease 72 Activated protein C resistance 72 inflammatory bowel disease 71 Severe sepsis 67 acute myocardial infarction 64 liver disease 63 multiple sclerosis 61 cardiovascular disease 61 Haemophilia 60 abortion 60 Protein C deficiency 59 ulcerative colitis 58 vascular disease 57 Lupus 57 haemophilia 56 anemia 53 Hippel 51 asthma 51 colitis 50 pneumonia 50 more...

Symptom respiratory distress 63 pain 59 abdominal pain 44 seizures 36 headache 36 anesthesia 34 hypothermia 23 starvation 22 dyspnea 21 diarrhea 21 collapse 19 vomiting 19 angina 19 chest pain 19 erythema 18 weakness 16 splenomegaly 15 functional recovery 14 exhaustion 14 livedo 13 overweight 11 nausea 9 hemiplegia 8 hypotonia 7 HSA 6 dysarthria 6 leg edema 6 hepatomegaly 6 paresis 6 hyperoxia 6 shortness of breath 6 chills 6 anorexia 5 epigastric pain 5 lethargy 5 tachypnea 5 analgesia 5 fatigue 5 dizziness 4 colic 4 hemoptysis 4 hepatosplenomegaly 4 Livedoid 4 ataxia 4 back pain 4 leg pain 3 cough 3 cyanosis 3 sleepiness 3 discomfort 3 syncope 3 discomfort 3 pallor 3 acidity 3 neuralgia 3 flushing 3 acute abdomen 3 chorea 2 spasm 2 exertional dyspnea 2 DNA marker 2 hypoproteinemia 2 intestinal bleeding 2 Ill 2 spasticity 2 arthralgia 2 asthenia 2 nausea and vomiting 2 anal pain 2 pelvic pain 2 acute abdominal pain 2 vertigo 2 cachexia 2 facial pain 2 right upper quadrant pain 2 thinning 2 Fluctuation 2 numbness 2 left upper quadrant pain 1 agitation 1 more...

Drug IFN-gamma 404 IL-2 380 CSF 94 lysine 78 Antithrombin III 72 Cardiovasc 69 Dermatol 60 Asn 45 Drotrecogin alfa 44 Drotrecogin alfa 44 PTC 42 Vitamin K 37 TAT 29 THF 28 CPT-11 24 CaCl2 22 CaCl2 22 CaCl2 22 Gel 21 Nephron 19 MAP 18 uPA 17 Irinotecan 17 Vitamin B12 15 Nephron 14 ROS 12 caffeine 12 Ximelagatran 12 Coumadin 10 G-CSF 10 Asthma 9 Fragment 9 CIA 9 Monit 9 Aprotinin 8 DNase I 8 Dial 8 ABC 8 ROC 8 DDAVP 7 DDAVP 7 Fraction 7 CTC 7 ascorbate 7 EPA 6 Valdecoxib 6 LMWH 6 DFP 6 L-Asparaginase 6 EE2 6 ENT 6 NADH 6 CTC 6 IL-11 6 BLM 6 Fondaparinux 5 IFN-beta 5 vitamin E 5 PCP 5 Lovastatin 5 CAM 5 nitroglycerin 5 Bevacizumab 5 CCL 5 Biopolymers 5 ACT 5 Fragmin 4 Alanine 4 ADR 4 Kaolin 4 ZnO 4 Urokinase 4 Paraffin 4 Parkin 4 L-tyrosine 4 Ancrod 4 p75 4 Copaxone 4 CTX 4 Heme 4 more...

Enzyme APC 16337 thrombin 2009 thromboplastin 817 tissue plasminogen activator 359 ERK 273 plasmin 218 proteasome 202 protein kinase 198 mitogen-activated protein kinase 188 urokinase-type plasminogen activator 121 trypsin 118 focal adhesion kinase 95 methylenetetrahydrofolate reductase 80 methylenetetrahydrofolate reductase 80 protein kinase C 69 kallikrein 65 cdc2 65 lysozyme 56 GSK 55 peroxidase 54 polo-like kinase 1 50 chymotrypsin 47 STK11 45 RNA polymerase 45 calcineurin 44 ATPase 43 separase 42 luciferase 40 MEK 37 caspase-3 36 thrombin-activatable fibrinolysis inhibitor 36 asparaginase 29 TAT 29 catalase 28 elastase 28 neutrophil elastase 26 alkaline phosphatase 24 glutathione S-transferase 23 PARP 23 superoxide dismutase 22 neuraminidase 21 tryptase 20 phospholipase A2 20 DNA polymerase 19 granzyme B 19 aspartate aminotransferase 19 alanine aminotransferase 18 ubiquitin-protein ligase 18 reverse transcriptase 17 CD10 16 AMPK 15 MAP 15 AMP-activated protein kinase 15 NO synthase 15 beta-galactosidase 15 SPC 13 ACS 13 DNA methyltransferase 13 RNase 13 cathepsin G 13 RNase 13 prostate-specific antigen 13 phosphatidylinositol 3-kinase 13 adenylate cyclase 12 MMP 12 endonuclease 11 cystathionine beta-synthase 11 BMT 11 carboxylesterase 11 protein phosphatase 2A 11 glutathione peroxidase 11 MIP 11 transcriptase 11 creatine kinase 10 CaMKII 10 phospholipase C 10 lactate dehydrogenase 10 carboxypeptidase B 10 collagenase 10 deaminase 9 more...

Compound DNA 1490 Dec 1185 Clin 876 calcium 482 arginine 384 Thrombin 270 serine 229 sodium 186 lysine 177 sulfate 161 alanine 149 oxygen 146 tyrosine 144 water 137 TNF 135 glucose 133 homocysteine 127 DCC 127 His 114 cysteine 108 methionine 106 SDS 105 threonine 103 Asp 99 acetate 98 Gly 91 phosphate 90 leucine 87 nitrogen 81 Heparin 77 nitric oxide 72 prostacyclin 72 Phe 71 Fibrinogen 70 hydrogen 67 glutamine 67 Cardiol 67 NH2 64 ATP 64 ADP 61 Warfarin 60 FAP 58 urea 58 FAP 58 ADP 52 salt 52 ADP 52 DIC 51 EDTA 50 PMA 48 cAMP 45 PMA 44 Ile 43 galactose 42 zinc 41 EDTA 41 creatinine 40 barium 39 glutamic acid 38 Vitamin K 37 Factor X 36 iron 36 proline 35 TEM 32 retinoic acid 32 PEG 31 NKT 31 PCI 30 FDP 29 COS 29 copper 29 SN-38 29 THP 28 THP 28 MTT 28 tryptophan 28 MEK 28 iodine 27 Estrogen 27 glutamate 25 more...

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