EC:3.4.21.69 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.4.21.69 (APC)
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Human Gene/Protein
APC	10.9
LONRF2	10.9
ZNF584	10.9
ZNF430	10.9
Protein C	10.9
CENTG3	10.9
ZBTB22	10.9
trigger of mitotic entry 1	10.9
CORT protein	10.9
protein C	10.9
GCST	10.9
USP37 protein	10.9
APC7	10.7
type I protein C	10.6
APC8	10.6
anaphase-promoting complex/cyclosome	10.6
plasma protein C	10.6
APC3	10.4
endothelial protein C receptor	10.3
tumor suppressor APC	10.2
APC4	10.2
protein S	10.0
KEN	10.0
KIAA1731	9.9
HCC5	9.9
CCDC84	9.9
G8 protein	9.9
PRGP1	9.9
ABTB2	9.9
AURKAIP1	9.9
early mitotic inhibitor 1	9.9
TPARL	9.9
VHL-like protein	9.9
MYH mRNA	9.9
MFSD9	9.9
ZNF688	9.9
IL-12R-beta2	9.9
MAD2L1 binding protein	9.9
B-cell CLL/lymphoma 9 protein	9.9
UBE2V	9.9

Disease
Omental gangrene	10.9
Acquired hypoprothrombinemia	10.9
MLVI2	10.9
APC	10.6
hereditary protein C deficiency	10.6
Protein C deficiency	10.6
Activated protein C resistance	10.5
PC deficiency	10.5
Sepsis with acute organ dysfunction	10.3
HPC4	10.2
Duodenal polyposis	9.9
Duodenal mass	9.9
Factor II mutation	9.9
Noninfective endocarditis	9.9
Acute coagulopathy	9.7
Antithrombin deficiency	9.6
Factor V Leiden mutation	9.5
MYH-associated polyposis	9.5
Coumarin necrosis	9.3
Protein S deficiency	9.2
Purpura fulminans	9.1
VKCFD1	8.9
Disorders of mitochondrial metabolism	8.9
Serrated adenoma	8.8
AAPC	8.7
Aberrant Crypt Foci	8.6
goiter with hyperthyroidism	8.6
epituberculosis	8.6
Familial Hypertrophic Cardiomyopathy	8.6
Thrombophilia	8.6
Severe sepsis	8.5
von Willebrand disease type 2N	8.3
Hypodysfibrinogenemia	8.3
Adenocarcinoma of the gastroesophageal junction	8.3
Neonatal thrombocytopenia	8.2
Turcot syndrome	8.1
familial adenomatous polyposis	8.1
fulminant purpura	8.1
Carotid artery thrombosis	8.1
MHS6	8.1

Symptom
Unexplained abdominal pain	7.8
Livedoid	7.3
Intermittent fever	7.2
Organ failure	5.0
livedo	4.9
leg edema	4.1
anal pain	4.0
left upper quadrant pain	3.9
Flare	3.5
peri-menopausal	3.4
Neurologic symptoms	3.4
impaired motor coordination	3.3
pedal edema	3.2
hyperemesis	2.7
Fluctuation	2.7
right lower quadrant pain	2.7
respiratory distress	2.6
right upper quadrant pain	2.5
eye pain	2.4
mastalgia	2.3
intestinal bleeding	2.3
Spots	2.1
DNA marker	2.1
HSA	2.0
hemiplegia	2.0
syncopal episodes	1.9
tachypnea	1.9
clumsiness	1.8
hypoproteinemia	1.8
neuralgia	1.7
presyncope	1.7
neck stiffness	1.7
dysarthria	1.6
splenomegaly	1.6
leg pain	1.5
epigastric pain	1.5
abdominal pain	1.5
chills	1.5
erythema	1.4
exertional angina	1.4

Drug
Efaproxiral sodium	10.9
Edodekin alfa	10.9
Selodenoson	10.9
Drotrecogin alfa	10.1
Drotrecogin alfa	10.1
Zofenopril calcium	9.1
Motexafin lutetium	8.6
Holin	8.6
APD-356	8.1
Antithrombin III	8.1
Percodan	7.9
Gemifloxacin mesylate	7.8
Zanolimumab	7.6
Desmoteplase	7.6
Parecoxib sodium	7.5
Ximelagatran	7.4
Fosamprenavir calcium	7.2
Z-Pro-Prolinal	7.2
Valdecoxib	7.0
Percocet	6.9
Valcyte	6.9
Kifunensine	6.9
Zomepirac sodium	6.9
OP-2	6.8
Hemolink	6.8
Bextra	6.8
Provenge	6.7
Warfarin sodium	6.6
Ziprasidone hydrochloride	6.5
Ecallantide	6.5
PT-141	6.5
Mononine	6.3
Ancrod	6.3
Antihemophilic factor	6.2
L-Asparaginase	6.1
Betamethasone dipropionate	6.1
Phenprocoumon	6.0
Dextran sulfate sodium	5.9
Coumadin	5.8
Palonosetron hydrochloride	5.8

Enzyme
choline-sulfatase	10.9
APC	10.9
sarcosine reductase	9.3
EC 5.4.99.15	8.6
thrombin-activatable fibrinolysis inhibitor	8.1
separase	7.9
duodenase	7.9
glycine reductase	7.9
succinyl-diaminopimelate desuccinylase	7.6
STK11	7.6
RVV-V	7.2
histidinol phosphate aminotransferase	7.0
thromboplastin	6.9
thrombin	6.9
phycocyanobilin:ferredoxin oxidoreductase	6.8
bacillolysin	6.6
vibriolysin	6.5
aminopeptidase Y	6.5
dichloromethane dehalogenase	6.5
C1 esterase	6.4
cancer procoagulant	6.4
methylenetetrahydrofolate reductase	6.2
methylenetetrahydrofolate reductase	6.2
granzyme M	6.1
polo-like kinase 1	6.0
tissue plasminogen activator	6.0
neurosin	5.9
TSR	5.8
coagulation factor XIa	5.7
acetylornithinase	5.6
plasmin	5.6
fibrolase	5.5
ubiquitin-protein ligase	5.5
dolichol kinase	5.0
carboxypeptidase B	5.0
Delta6-desaturase	5.0
deoxyhypusine hydroxylase	4.9
tripeptidase	4.9
MHCK	4.8
CPN	4.7