Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.69 (APC)
16,337 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
APC 8035
protein C 6318
thrombin 2049
protein S 2009
prothrombin 1274
Sep 1100
antithrombin 1029
antithrombin III 1022
thrombomodulin 946
Protein C 918
fibrinogen 917
p53 807
factor V 705
Mol 704
factor V Leiden 677
CD4 613
cytokine 539
TCR 519
MHC 495
thromboplastin 473
anaphase-promoting complex/cyclosome 451
beta-catenin 447
plasminogen 432
tissue factor 405
IFN-gamma 405
factor VIII 403
catenin 394
IL-2 380
CD8 377
factor Xa 360
MHC class II 357
ubiquitin 328
ubiquitin ligase 302
KRAS 302
Protein S 288
VIII 272
von Willebrand factor 259
serine protease 257
PLA 248
factor VII 248
more...
Disease
APC 8035
cancer 2198
tumor 1837
colorectal cancer 930
sepsis 683
sepsis 672
familial adenomatous polyposis 630
carcinogenesis 495
tumorigenesis 478
systemic lupus erythematosus 452
carcinoma 412
lupus 406
disseminated intravascular coagulation 394
deep vein thrombosis 393
lupus 362
colon cancer 348
stroke 312
adenoma 289
polyposis 282
coagulopathy 231
adenocarcinoma 225
pulmonary embolism 209
diabetes 197
breast cancer 179
purpura 166
antiphospholipid syndrome 166
tumor progression 156
myocardial infarction 144
ischemia 143
atherosclerosis 142
metastases 137
thrombocytopenia 135
tumor growth 132
hyperhomocysteinemia 126
PC deficiency 125
HIV 115
dysplasia 115
gastric cancer 114
Thrombophilia 111
hypertension 109
more...
Symptom
respiratory distress 63
pain 59
abdominal pain 44
headache 36
seizures 36
anesthesia 34
hypothermia 23
starvation 22
dyspnea 21
diarrhea 21
chest pain 19
collapse 19
vomiting 19
angina 19
erythema 18
weakness 16
splenomegaly 15
exhaustion 14
functional recovery 14
livedo 13
overweight 11
nausea 9
hemiplegia 8
hypotonia 7
dysarthria 6
shortness of breath 6
leg edema 6
hepatomegaly 6
paresis 6
hyperoxia 6
HSA 6
chills 6
lethargy 5
epigastric pain 5
fatigue 5
anorexia 5
tachypnea 5
analgesia 5
hepatosplenomegaly 4
back pain 4
more...
Drug
IFN-gamma 404
IL-2 380
CSF 94
lysine 78
Antithrombin III 72
Cardiovasc 69
Dermatol 60
Asn 45
Drotrecogin alfa 44
Drotrecogin alfa 44
PTC 42
Vitamin K 37
TAT 29
THF 28
CPT-11 24
CaCl2 22
CaCl2 22
CaCl2 22
Gel 21
Nephron 19
MAP 18
uPA 17
Irinotecan 17
Vitamin B12 15
Nephron 14
ROS 12
caffeine 12
Ximelagatran 12
Coumadin 10
G-CSF 10
Asthma 9
Fragment 9
Monit 9
CIA 9
Dial 8
ABC 8
DNase I 8
Aprotinin 8
ROC 8
Fraction 7
more...
Enzyme
APC 16337
thrombin 2009
thromboplastin 817
tissue plasminogen activator 359
ERK 273
plasmin 218
proteasome 202
protein kinase 198
mitogen-activated protein kinase 188
urokinase-type plasminogen activator 121
trypsin 118
focal adhesion kinase 95
methylenetetrahydrofolate reductase 80
methylenetetrahydrofolate reductase 80
protein kinase C 69
kallikrein 65
cdc2 65
lysozyme 56
GSK 55
peroxidase 54
polo-like kinase 1 50
chymotrypsin 47
STK11 45
RNA polymerase 45
calcineurin 44
ATPase 43
separase 42
luciferase 40
MEK 37
thrombin-activatable fibrinolysis inhibitor 36
caspase-3 36
asparaginase 29
TAT 29
catalase 28
elastase 28
neutrophil elastase 26
alkaline phosphatase 24
glutathione S-transferase 23
PARP 23
superoxide dismutase 22
more...
Compound
DNA 1490
Dec 1185
Clin 876
calcium 482
arginine 384
Thrombin 270
serine 229
sodium 186
lysine 177
sulfate 161
alanine 149
oxygen 146
tyrosine 144
water 137
TNF 135
glucose 133
homocysteine 127
DCC 127
His 114
cysteine 108
methionine 106
SDS 105
threonine 103
Asp 99
acetate 98
Gly 91
phosphate 90
leucine 87
nitrogen 81
Heparin 77
prostacyclin 72
nitric oxide 72
Phe 71
Fibrinogen 70
hydrogen 67
Cardiol 67
glutamine 67
NH2 64
ATP 64
ADP 61
more...