Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.69 (
APC
)
16,337
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
APC
8035
protein C
6318
thrombin
2049
protein S
2009
prothrombin
1274
Sep
1100
antithrombin
1029
antithrombin III
1022
thrombomodulin
946
Protein C
918
fibrinogen
917
p53
807
factor V
705
Mol
704
factor V Leiden
677
CD4
613
cytokine
539
TCR
519
MHC
495
thromboplastin
473
more...
Disease
APC
8035
cancer
2198
tumor
1837
colorectal cancer
930
sepsis
683
sepsis
672
familial adenomatous polyposis
630
carcinogenesis
495
tumorigenesis
478
systemic lupus erythematosus
452
carcinoma
412
lupus
406
disseminated intravascular coagulation
394
deep vein thrombosis
393
lupus
362
colon cancer
348
stroke
312
adenoma
289
polyposis
282
coagulopathy
231
more...
Symptom
respiratory distress
63
pain
59
abdominal pain
44
headache
36
seizures
36
anesthesia
34
hypothermia
23
starvation
22
dyspnea
21
diarrhea
21
angina
19
collapse
19
vomiting
19
chest pain
19
erythema
18
weakness
16
splenomegaly
15
exhaustion
14
functional recovery
14
livedo
13
more...
Drug
IFN-gamma
404
IL-2
380
CSF
94
lysine
78
Antithrombin III
72
Cardiovasc
69
Dermatol
60
Asn
45
Drotrecogin alfa
44
Drotrecogin alfa
44
PTC
42
Vitamin K
37
TAT
29
THF
28
CPT-11
24
CaCl2
22
CaCl2
22
CaCl2
22
Gel
21
Nephron
19
more...
Enzyme
APC
16337
thrombin
2009
thromboplastin
817
tissue plasminogen activator
359
ERK
273
plasmin
218
proteasome
202
protein kinase
198
mitogen-activated protein kinase
188
urokinase-type plasminogen activator
121
trypsin
118
focal adhesion kinase
95
methylenetetrahydrofolate reductase
80
methylenetetrahydrofolate reductase
80
protein kinase C
69
kallikrein
65
cdc2
65
lysozyme
56
GSK
55
peroxidase
54
more...
Compound
DNA
1490
Dec
1185
Clin
876
calcium
482
arginine
384
Thrombin
270
serine
229
sodium
186
lysine
177
sulfate
161
alanine
149
oxygen
146
tyrosine
144
water
137
TNF
135
glucose
133
DCC
127
homocysteine
127
His
114
cysteine
108
more...