Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.69 (
APC
)
16,337
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We describe a positional proteomics approach to simultaneously analyze N- and C-terminal peptides and used it to screen for human protein substrates of granzyme B and
carboxypeptidase A4
in human cell lysates. This approach allowed comprehensive proteome studies, and we report the identification of 965 database-annotated
protein C
termini, 334 neo-C termini resulting from granzyme B processing and 16 neo-C termini resulting from
carboxypeptidase A4
processing.
...
PMID:Complementary positional proteomics for screening substrates of endo- and exoproteases. 2052 45
