Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.68 (tissue plasminogen activator)
 11,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tissue plasminogen activator 0.554
PLA 0.169
tPA 0.109
plasminogen 0.046
plasminogen activator inhibitor-1 0.036
plasminogen activator inhibitor 0.035
urokinase-type plasminogen activator 0.030
u-PA 0.012
Plasminogen 0.009
PAI 0.007
fibrinogen 0.005
PAI-2 0.004
thrombin 0.003
Tissue plasminogen activator 0.002
Plasmin 0.002
urokinase plasminogen activator 0.002
inhibitor-1 0.002
antithrombin III 0.002
alpha 2-plasmin inhibitor 0.002
neuroserpin 0.002
thrombomodulin 0.002
von Willebrand factor 0.001
thrombin-activatable fibrinolysis inhibitor 0.001
Neuroserpin 0.001
protein C 0.001
antithrombin 0.001
tissue factor 0.001
prothrombin 0.001
factor VII 0.001
protein S 0.001
serine protease 0.001
FDP 0.000
annexin II 0.000
thromboplastin 0.000
tissue factor pathway inhibitor 0.000
lipoprotein receptor-related protein 0.000
uPAR 0.000
PLAT 0.000
Lp(a) 0.000
vWF 0.000
penumbra 0.000
factor XII 0.000
plasminogen activator inhibitor 2 0.000
annexin A2 0.000
histidine-rich glycoprotein 0.000
heparin cofactor II 0.000
factor Xa 0.000
TPA 0.000
serine protease inhibitor 0.000
beta-thromboglobulin 0.000
vitronectin 0.000
PAI1 0.000
plasminogen-like 0.000
nexin 0.000
thrombin inhibitor 0.000
plasmin precursor 0.000
carboxypeptidase B 0.000
tissue plasminogen activator precursor 0.000
matrix metalloproteinase 0.000
factor VIII 0.000
Protein C 0.000
GPIIb 0.000
MMP-9 0.000
kallikrein 0.000
vascular endothelium 0.000
LRP-DIT 0.000
SERPINE2 protein 0.000
rho GTPase activating protein 0.000
C9orf46 0.000
factor XIIIa 0.000
Prothrombin 0.000
Urokinase plasminogen activator 0.000
Fibrinopeptide A 0.000
fibronectin 0.000
TMPRSS5 0.000
platelet factor 4 0.000
bradykinin 0.000
MMP-2 0.000
LRP 0.000
gene trap ankyrin repeat 0.000
more...
Disease
stroke 0.003
acute myocardial infarction 0.002
coronary thrombosis 0.001
Acute Stroke 0.001
Ischemic stroke 0.000
myocardial infarction 0.000
Thrombus 0.000
pulmonary embolism 0.000
cerebral ischemia 0.000
PLAT 0.000
ischemia 0.000
deep vein thrombosis 0.000
cerebral infarction 0.000
Pleural infection 0.000
disseminated intravascular coagulation 0.000
venous stasis 0.000
Subretinal hemorrhage 0.000
Congenital dysfibrinogenemia 0.000
atherosclerosis 0.000
Plastic bronchitis 0.000
dysfibrinogenemia 0.000
coagulopathy 0.000
Saddle PE 0.000
Brain Ischemia 0.000
veno-occlusive disease 0.000
Embolic stroke 0.000
Pulmonary artery thrombosis 0.000
Vascular thoracic outlet syndrome 0.000
Coronary artery reocclusion 0.000
FENIB 0.000
Suprachoroidal hemorrhage 0.000
unstable angina 0.000
Livedo vasculitis 0.000
Corticosteroid-induced glaucoma 0.000
Systemic fibrinogenolysis 0.000
Acute transmural myocardial infarction 0.000
DWI 0.000
SDS 0.000
Livedoid vasculitis 0.000
Post MI 0.000
hepatic veno-occlusive disease 0.000
cardiovascular disease 0.000
neurological disease 0.000
hypofibrinogenemia 0.000
Recurrent pulmonary embolism 0.000
coronary artery disease 0.000
coronary heart disease 0.000
Acute coagulopathy 0.000
subarachnoid hemorrhage 0.000
cerebral embolism 0.000
hypertension 0.000
PLG 0.000
global aphasia 0.000
brain edema 0.000
melanoma 0.000
hemiparesis 0.000
XDP 0.000
Middle cerebral artery occlusion 0.000
Staphylococcal endocarditis 0.000
vascular disease 0.000
Thrombophilia 0.000
cerebral vasospasm 0.000
Choroidal neovascular membrane 0.000
von Willebrand disease 0.000
Acute massive pulmonary embolism 0.000
postphlebitic syndrome 0.000
Transmural myocardial infarction 0.000
Retinal atrophy 0.000
HPC4 0.000
transient ischemic attack 0.000
cerebrovascular occlusion 0.000
Anaphylactoid reaction 0.000
aphasia 0.000
Aortic valve sclerosis 0.000
Essential mixed cryoglobulinemia 0.000
Plasminogen deficiency 0.000
diabetes 0.000
inferior myocardial infarction 0.000
antiphospholipid syndrome 0.000
myocardial ischemia 0.000
more...
Symptom
chest pain 0.000
Upper back pain 0.000
Lower extremity weakness 0.000
facial droop 0.000
angina 0.000
hemiplegia 0.000
functional recovery 0.000
Mental status changes 0.000
dysarthria 0.000
hypothermia 0.000
disturbed balance 0.000
neurological disability 0.000
finger pain 0.000
Livedoid 0.000
thoracic back pain 0.000
consciousness disturbance 0.000
respiratory distress 0.000
localized edema 0.000
weakness 0.000
monoplegia 0.000
pain 0.000
dyspnea 0.000
livedo 0.000
overweight 0.000
hyperoxia 0.000
seizures 0.000
anesthesia 0.000
arm weakness 0.000
exertional angina 0.000
syncope 0.000
spasm 0.000
shortness of breath 0.000
paraparesis 0.000
dysesthesia 0.000
pleuritic chest pain 0.000
Fluctuation 0.000
presyncope 0.000
persistent cough 0.000
tachypnea 0.000
non-productive cough 0.000
dark urine 0.000
forgetfulness 0.000
flank pain 0.000
rigors 0.000
abdominal pain 0.000
Scratch 0.000
cyanosis 0.000
numbness 0.000
neck pain 0.000
orthopnea 0.000
stomach pain 0.000
acute stress 0.000
Catch 0.000
blurred vision 0.000
POA 0.000
exertional dyspnea 0.000
clumsiness 0.000
hyperemesis gravidarum 0.000
Anoxia 0.000
nasal discharge 0.000
neck stiffness 0.000
headache 0.000
atypical chest pain 0.000
pelvic pain 0.000
nausea 0.000
collapse 0.000
hemoptysis 0.000
chills 0.000
back pain 0.000
neuralgia 0.000
ataxia 0.000
incoordination 0.000
dizziness 0.000
intestinal bleeding 0.000
renal colic 0.000
exhaustion 0.000
vomiting 0.000
leg pain 0.000
regurgitation 0.000
hepatomegaly 0.000
more...
Drug
uPA 0.006
Alteplase 0.003
Alteplase 0.003
Alteplase 0.003
Streptokinase 0.001
Activase 0.001
Urokinase 0.001
Pamiteplase 0.000
Desmoteplase 0.000
Tenecteplase 0.000
Monteplase 0.000
Lanoteplase 0.000
Prolyse 0.000
DDAVP 0.000
DDAVP 0.000
lysine 0.000
Cyclotheonamide A 0.000
Actimmune 0.000
Argatroban 0.000
Ancrod 0.000
Aprotinin 0.000
Trafermin 0.000
TAT 0.000
Hirulog 0.000
Sibrafiban 0.000
Optison 0.000
Sulotroban 0.000
Antithrombin III 0.000
Batroxobin 0.000
Desmopressin acetate 0.000
DFP 0.000
Cardiovasc 0.000
Foscavir 0.000
Ecallantide 0.000
Diastat 0.000
Asn 0.000
Abciximab 0.000
Calciparine 0.000
Optison 0.000
Thrombostat 0.000
Adenosine Monophosphate 0.000
Iopromide 0.000
Cyclandelate 0.000
Acadesine 0.000
Polyacrylic acid 0.000
C3F8 0.000
Ridogrel 0.000
Eptifibatide 0.000
CGS 13080 0.000
LCBF 0.000
Dalteparin 0.000
Pulmozyme 0.000
Gemfibrozil 0.000
G418 0.000
CS-514 0.000
SF6 0.000
Beraprost 0.000
nitroglycerin 0.000
Gliclazide 0.000
Iloprost 0.000
Chloramine T 0.000
Retinoic acid 0.000
Tiaprofenic acid 0.000
Nafamostat mesilate 0.000
Enalaprilat 0.000
FeCl3 0.000
Enalaprilat 0.000
Trental 0.000
ACT 0.000
Orgaran 0.000
Omapatrilat 0.000
balanced salt solution 0.000
Hyoscyamine 0.000
Fondaparinux 0.000
Cangrelor 0.000
Fragmin 0.000
Coumadin 0.000
LMWH 0.000
Dazoxiben 0.000
Clopidogrel 0.000
more...
Enzyme
tissue plasminogen activator 1.000
urokinase-type plasminogen activator 0.034
plasmin 0.024
thrombin 0.003
thrombin-activatable fibrinolysis inhibitor 0.001
APC 0.001
thromboplastin 0.001
ancrod 0.000
kallikrein 0.000
carboxypeptidase B 0.000
trypsin 0.000
kyotorphin synthetase 0.000
elastase 0.000
neuropsin 0.000
TAT 0.000
complement subcomponent C1r 0.000
matrix metalloproteinase 9 0.000
MMP-3 0.000
neuropsin 0.000
deoxyribonuclease 0.000
deoxyribonuclease 0.000
neutrophil elastase 0.000
CPN 0.000
collagenase 0.000
tissue kallikrein 0.000
MMP 0.000
NS protease 0.000
destabilase 0.000
fibrolase 0.000
matrix metalloproteinase 2 0.000
chymotrypsin 0.000
cathepsin G 0.000
DNase 0.000
ACE 0.000
clotting enzyme 0.000
ADPase 0.000
neurosin 0.000
macrophage elastase 0.000
creatine kinase 0.000
Hageman factor 0.000
renin 0.000
cathepsin D 0.000
thromboxane synthase 0.000
interstitial collagenase 0.000
mitogen-activated protein kinase 0.000
PNGase F 0.000
endoglycosidase H 0.000
heparinase 0.000
apyrase 0.000
enolase 0.000
protein kinase C 0.000
protease La 0.000
hepsin 0.000
hepsin 0.000
STK 0.000
chondroitinase 0.000
chondroitinase 0.000
tryptase 0.000
protein L-isoaspartyl methyltransferase 0.000
BMT 0.000
matriptase 0.000
cancer procoagulant 0.000
coagulation factor VIIa 0.000
chymase 0.000
LMT 0.000
site-1 protease 0.000
transglutaminase 0.000
FAST 0.000
versatile peroxidase 0.000
lipoprotein lipase 0.000
matriptase 0.000
methylenetetrahydrofolate reductase 0.000
methylenetetrahydrofolate reductase 0.000
protein kinase 0.000
peroxidase 0.000
NO synthase 0.000
jararhagin 0.000
factor C 0.000
dihydrofolate reductase 0.000
cathepsin H 0.000
more...
Compound
Plasmin 0.002
Fibrin 0.001
Fibrinogen 0.001
6-aminohexanoic acid 0.000
6-aminohexanoic acid 0.000
FDP 0.000
Thrombin 0.000
FCB 0.000
lysine 0.000
AEK 0.000
Heparin 0.000
prostacyclin 0.000
Tranexamic acid 0.000
1,3,7-Trihydroxyxanthone 0.000
TPA 0.000
TPA 0.000
serine 0.000
Fibrinopeptide A 0.000
Cardiol 0.000
Edaravone 0.000
arginine 0.000
Promazine hydrochloride 0.000
Scolymoside 0.000
Cereb 0.000
SDS 0.000
Argatroban 0.000
5-amino-2-naphthalenesulfonic acid 0.000
PAR 0.000
Ginkgolide C 0.000
ADP 0.000
2,3-dinor-thromboxane 0.000
diphenyl phosphonate 0.000
ASA 0.000
N-methylpropanamide 0.000
Dec 0.000
Ginkgolide J 0.000
ADP 0.000
homocysteine 0.000
ADP 0.000
Methacycline 0.000
Desmopressin 0.000
Clin 0.000
Pipecolic acid 0.000
Piperlonguminine 0.000
Ginkgolide C 0.000
retinoic acid 0.000
sulfate 0.000
Factor X 0.000
Bradykinin 0.000
acetate 0.000
Tirofiban 0.000
cyclooctanone 0.000
glucose 0.000
piperidine-2-carboxylic acid 0.000
Fucoidan 0.000
cycloheptanone 0.000
cyclooctanone 0.000
4-fluorotryptophan 0.000
sodium 0.000
Stanozolol 0.000
Stanozolol 0.000
DIC 0.000
Methyl isocyanate 0.000
Stanozolol 0.000
8-quinolinyl 0.000
EGT 0.000
nitric oxide 0.000
Warfarin 0.000
Ginkgolide A 0.000
Droloxifene 0.000
DNA 0.000
Bullatacin 0.000
Chondroitin 6-sulfate 0.000
calcium 0.000
15-Hydroxyeicosatetraenoic acid 0.000
NH4OH 0.000
6-Keto-PGF1a 0.000
oxygen 0.000
Fluvastatin 0.000
cAMP 0.000
more...