Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.68 (tissue plasminogen activator)
11,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tissue plasminogen activator 6267 PLA 5663 plasminogen 2292 urokinase-type plasminogen activator 1827 plasminogen activator inhibitor-1 1612 fibrinogen 1300 plasminogen activator inhibitor 1281 tPA 1232 thrombin 1089 Sep 795 Plasminogen 443 von Willebrand factor 403 antithrombin III 342 prothrombin 341 PAI 298 Mol 285 protein C 273 u-PA 268 insulin 252 serine protease 244 antithrombin 239 tissue factor 232 thrombomodulin 222 thromboplastin 208 collagen 204 SDS 176 urokinase plasminogen activator 163 fibronectin 161 glycoprotein 161 Plasmin 154 inhibitor-1 152 protein S 151 factor VII 145 matrix metalloproteinase 145 PAI-2 138 C-reactive protein 123 cytokine 114 tumor necrosis factor 113 factor VIII 110 bradykinin 110 factor Xa 108 Tissue plasminogen activator 107 MMP-9 106 vascular endothelium 103 ADP 100 TPA 99 Lp(a) 98 uPAR 94 alpha 2-plasmin inhibitor 93 penumbra 91 vitronectin 89 epidermal growth factor 86 albumin 86 She 84 MMP-2 83 MRI 79 TNF 75 thrombin-activatable fibrinolysis inhibitor 74 tissue factor pathway inhibitor 74 annexin II 72 kallikrein 71 polypeptide 71 serine protease inhibitor 70 HDL 67 FDP 67 vWF 67 hemoglobin 66 neuroserpin 64 vascular endothelial growth factor 64 lipopolysaccharide 62 VIII 61 brain-derived neurotrophic factor 60 GPIIb 60 fused 59 lipoprotein receptor-related protein 59 beta-thromboglobulin 59 IL-6 57 renin 56 Pol 56 factor XII 55 more...

Disease stroke 2228 acute myocardial infarction 695 myocardial infarction 560 ischemia 449 cancer 342 atherosclerosis 308 tumor 276 hypertension 269 cerebral ischemia 245 diabetes 240 pulmonary embolism 231 cardiovascular disease 182 SDS 176 melanoma 166 deep vein thrombosis 159 coronary artery disease 143 disseminated intravascular coagulation 122 cerebral infarction 114 obesity 107 coronary heart disease 102 coronary thrombosis 101 Thrombus 91 coagulopathy 91 sepsis 85 Ischemic stroke 82 plaque 78 carcinoma 77 myocardial ischemia 77 vascular disease 76 Alzheimer's disease 75 sepsis 74 breast cancer 71 subarachnoid hemorrhage 71 systemic lupus erythematosus 68 neurological disease 67 unstable angina 65 SEM 64 heart failure 63 type 2 diabetes 62 hepatocellular carcinoma 57 hyperlipidemia 54 Acute Stroke 53 hemiparesis 50 thrombocytopenia 50 metastases 49 lupus 49 depression 43 hyperglycemia 43 cirrhosis 43 brain edema 42 lupus 42 congestive heart failure 41 tumor growth 41 venous stasis 37 aphasia 37 pneumonia 35 dementia 35 renal disease 34 transient ischemic attack 32 hypercholesterolemia 32 veno-occlusive disease 32 von Willebrand disease 32 leukemia 31 HIV 31 preeclampsia 31 antiphospholipid syndrome 30 essential hypertension 30 dyslipidemia 29 pulmonary hypertension 29 hyperinsulinemia 29 liver disease 28 metabolic syndrome 28 heart disease 28 cold 27 haemophilia 27 multiple myeloma 26 fibrosarcoma 26 coma 26 acute promyelocytic leukemia 26 macular degeneration 25 more...

Symptom chest pain 104 pain 95 angina 69 functional recovery 53 anesthesia 50 hypothermia 46 seizures 44 weakness 36 respiratory distress 32 hemiplegia 29 dyspnea 28 overweight 26 dysarthria 22 headache 18 abdominal pain 17 syncope 13 collapse 12 nausea 11 spasm 11 vomiting 11 hyperoxia 11 shortness of breath 9 neurological disability 9 ataxia 8 discomfort 7 exhaustion 7 discomfort 7 back pain 7 diarrhea 7 paraparesis 6 facial droop 6 dizziness 6 analgesia 6 fatigue 6 tremor 6 numbness 6 consciousness disturbance 6 starvation 6 hemoptysis 5 agitation 5 regurgitation 5 tachypnea 5 acute stress 5 cyanosis 5 neck pain 5 exertional dyspnea 4 cough 4 pelvic pain 4 flushing 4 disturbed balance 4 flank pain 4 hepatomegaly 4 vertigo 4 livedo 4 chills 4 dysesthesia 3 lethargy 3 exertional angina 3 blurred vision 3 low back pain 3 hypercapnia 2 persistent cough 2 pleuritic chest pain 2 forgetfulness 2 rigors 2 leg pain 2 nasal discharge 2 constipation 2 paresis 2 neuralgia 2 stridor 2 anorexia 2 Fluctuation 2 erythema 2 incoordination 2 sleepiness 2 facial pain 2 presyncope 2 nausea and vomiting 2 thinning 2 more...

Drug uPA 386 lysine 325 Cardiovasc 187 Alteplase 98 Alteplase 91 Streptokinase 91 Alteplase 88 Urokinase 79 Asn 43 DDAVP 43 DDAVP 42 TAT 32 Dermatol 30 nitroglycerin 24 Activase 22 Aprotinin 22 Gel 20 Dial 19 CSF 19 CaCl2 15 CaCl2 15 CaCl2 15 MAP 14 Nephron 14 ascorbate 14 Retinoic acid 14 DFP 12 Nephron 12 G418 12 Argatroban 12 Tenecteplase 12 Antithrombin III 11 ABC 10 Optison 10 ACT 10 IFN-gamma 10 Angiotensin II 9 Monit 9 Fragment 8 balanced salt solution 8 EE2 8 FeCl3 8 SF6 7 Fluorescein 7 p75 7 Ancrod 7 TTC 6 Abciximab 6 Ringer's solution 6 Gelatin 6 Clopidogrel 6 ROS 6 Ethanol 6 Simvastatin 6 Fluorescein 6 ROC 6 CTA 6 MRC 6 Desmoteplase 5 vitamin E 5 Amiloride 5 EPA 5 Iloprost 5 Ginseng 5 Dalteparin 5 IL-2 5 Glucagon 5 Amiloride 5 DNase I 5 CPR 5 Pamiteplase 4 PTC 4 Monteplase 4 Serum albumin 4 THF 4 Gemfibrozil 4 G-CSF 4 Pravastatin 4 Hirulog 4 Alliance 4 more...

Enzyme tissue plasminogen activator 11311 urokinase-type plasminogen activator 2035 plasmin 1564 thrombin 1062 APC 359 thromboplastin 297 trypsin 184 kallikrein 109 mitogen-activated protein kinase 88 collagenase 69 elastase 67 renin 56 protein kinase C 55 thrombin-activatable fibrinolysis inhibitor 55 ACE 51 protein kinase 48 chymotrypsin 43 peroxidase 42 creatine kinase 42 ERK 41 neutrophil elastase 36 MMP-3 36 DNase 34 carboxypeptidase B 32 TAT 32 MMP 31 matrix metalloproteinase 9 30 superoxide dismutase 26 lactate dehydrogenase 25 deoxyribonuclease 22 deoxyribonuclease 22 ancrod 22 caspase-3 22 matrix metalloproteinase 2 20 NO synthase 20 focal adhesion kinase 18 cathepsin D 18 phosphodiesterase 18 tissue kallikrein 17 reverse transcriptase 17 cathepsin G 16 luciferase 15 RNase 15 RNase 15 enolase 15 lipoprotein lipase 14 phospholipase A2 13 alkaline phosphatase 13 catalase 13 transglutaminase 12 beta-galactosidase 12 proteasome 12 endoglycosidase H 11 adenylate cyclase 11 glutathione S-transferase 11 dihydrofolate reductase 11 hyaluronidase 11 tryptase 11 BMT 10 CPN 10 chondroitinase 10 deaminase 10 chondroitinase 10 glyceraldehyde-3-phosphate dehydrogenase 10 apyrase 10 PNGase F 10 heparinase 9 lipoxygenase 9 ribonuclease 9 ribonuclease 9 glyceraldehyde-3-phosphate dehydrogenase 9 chloramphenicol acetyltransferase 9 interstitial collagenase 8 aspartate aminotransferase 8 subtilisin 8 phospholipase C 8 ATPase 7 PARP 7 AMPK 7 methylenetetrahydrofolate reductase 7 more...

Compound Dec 794 Clin 638 Cardiol 440 lysine 416 DNA 324 arginine 256 serine 251 glucose 232 sodium 218 oxygen 203 calcium 199 SDS 187 sulfate 154 acetate 151 Fibrin 148 Plasmin 146 prostacyclin 140 Fibrinogen 136 ADP 127 Thrombin 126 nitric oxide 117 ADP 100 ADP 100 Heparin 98 Cereb 95 water 90 cAMP 79 galactose 78 TNF 75 TPA 74 retinoic acid 74 TPA 74 ASA 72 alanine 70 FDP 67 His 66 cysteine 60 Gly 58 homocysteine 55 ACS 55 Asp 53 Phe 52 copper 52 methionine 49 phosphate 48 glutamate 47 AMP 45 creatinine 45 leucine 44 NH2 41 EDTA 40 salt 39 tyrosine 37 ethanol 37 6-aminohexanoic acid 36 6-aminohexanoic acid 36 glutamic acid 36 zinc 35 threonine 35 Insulin 34 PAR 34 TEM 32 NMDA 32 urea 32 PEG 32 EDTA 32 MDA 31 ATP 29 iron 26 Ile 26 glutamine 25 CO2 24 Tranexamic acid 24 hydrogen 24 aldosterone 23 Estrogen 22 ammonium 22 asparagine 21 PEG 21 proline 21 more...

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