Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.68 (tissue plasminogen activator)
11,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tissue plasminogen activator 6267 PLA 5663 plasminogen 2292 urokinase-type plasminogen activator 1827 plasminogen activator inhibitor-1 1612 fibrinogen 1300 plasminogen activator inhibitor 1281 tPA 1232 thrombin 1089 Sep 795 Plasminogen 443 von Willebrand factor 403 antithrombin III 342 prothrombin 341 PAI 298 Mol 285 protein C 273 u-PA 268 insulin 252 serine protease 244 antithrombin 239 tissue factor 232 thrombomodulin 222 thromboplastin 208 collagen 204 SDS 176 urokinase plasminogen activator 163 fibronectin 161 glycoprotein 161 Plasmin 154 inhibitor-1 152 protein S 151 factor VII 145 matrix metalloproteinase 145 PAI-2 138 C-reactive protein 123 cytokine 114 tumor necrosis factor 113 factor VIII 110 bradykinin 110 more...

Disease stroke 2228 acute myocardial infarction 695 myocardial infarction 560 ischemia 449 cancer 342 atherosclerosis 308 tumor 276 hypertension 269 cerebral ischemia 245 diabetes 240 pulmonary embolism 231 cardiovascular disease 182 SDS 176 melanoma 166 deep vein thrombosis 159 coronary artery disease 143 disseminated intravascular coagulation 122 cerebral infarction 114 obesity 107 coronary heart disease 102 coronary thrombosis 101 Thrombus 91 coagulopathy 91 sepsis 85 Ischemic stroke 82 plaque 78 carcinoma 77 myocardial ischemia 77 vascular disease 76 Alzheimer's disease 75 sepsis 74 subarachnoid hemorrhage 71 breast cancer 71 systemic lupus erythematosus 68 neurological disease 67 unstable angina 65 SEM 64 heart failure 63 type 2 diabetes 62 hepatocellular carcinoma 57 more...

Symptom chest pain 104 pain 95 angina 69 functional recovery 53 anesthesia 50 hypothermia 46 seizures 44 weakness 36 respiratory distress 32 hemiplegia 29 dyspnea 28 overweight 26 dysarthria 22 headache 18 abdominal pain 17 syncope 13 collapse 12 hyperoxia 11 spasm 11 vomiting 11 nausea 11 shortness of breath 9 neurological disability 9 ataxia 8 back pain 7 diarrhea 7 discomfort 7 discomfort 7 exhaustion 7 dizziness 6 analgesia 6 starvation 6 fatigue 6 tremor 6 numbness 6 consciousness disturbance 6 facial droop 6 paraparesis 6 regurgitation 5 cyanosis 5 more...

Drug uPA 386 lysine 325 Cardiovasc 187 Alteplase 98 Alteplase 91 Streptokinase 91 Alteplase 88 Urokinase 79 DDAVP 43 Asn 43 DDAVP 42 TAT 32 Dermatol 30 nitroglycerin 24 Activase 22 Aprotinin 22 Gel 20 CSF 19 Dial 19 CaCl2 15 CaCl2 15 CaCl2 15 ascorbate 14 Retinoic acid 14 MAP 14 Nephron 14 Tenecteplase 12 DFP 12 G418 12 Argatroban 12 Nephron 12 Antithrombin III 11 Optison 10 ACT 10 IFN-gamma 10 ABC 10 Angiotensin II 9 Monit 9 EE2 8 FeCl3 8 more...

Enzyme tissue plasminogen activator 11311 urokinase-type plasminogen activator 2035 plasmin 1564 thrombin 1062 APC 359 thromboplastin 297 trypsin 184 kallikrein 109 mitogen-activated protein kinase 88 collagenase 69 elastase 67 renin 56 thrombin-activatable fibrinolysis inhibitor 55 protein kinase C 55 ACE 51 protein kinase 48 chymotrypsin 43 creatine kinase 42 peroxidase 42 ERK 41 neutrophil elastase 36 MMP-3 36 DNase 34 carboxypeptidase B 32 TAT 32 MMP 31 matrix metalloproteinase 9 30 superoxide dismutase 26 lactate dehydrogenase 25 deoxyribonuclease 22 caspase-3 22 ancrod 22 deoxyribonuclease 22 matrix metalloproteinase 2 20 NO synthase 20 cathepsin D 18 phosphodiesterase 18 focal adhesion kinase 18 reverse transcriptase 17 tissue kallikrein 17 more...

Compound Dec 794 Clin 638 Cardiol 440 lysine 416 DNA 324 arginine 256 serine 251 glucose 232 sodium 218 oxygen 203 calcium 199 SDS 187 sulfate 154 acetate 151 Fibrin 148 Plasmin 146 prostacyclin 140 Fibrinogen 136 ADP 127 Thrombin 126 nitric oxide 117 ADP 100 ADP 100 Heparin 98 Cereb 95 water 90 cAMP 79 galactose 78 TNF 75 TPA 74 retinoic acid 74 TPA 74 ASA 72 alanine 70 FDP 67 His 66 cysteine 60 Gly 58 homocysteine 55 ACS 55 more...

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