Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.68 (tissue plasminogen activator)
 11,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tPA 11.5
tissue plasminogen activator 11.5
tissue plasminogen activator precursor 11.5
u-PA 10.5
plasmin precursor 10.5
rho GTPase activating protein 10.5
SERPINE2 protein 10.5
C9orf46 10.5
LRP-DIT 10.5
Neuroserpin 10.1
PLA 9.9
TMPRSS5 9.9
neuroserpin 9.8
plasminogen activator inhibitor 9.8
PAI-2 9.7
PAI 9.5
plasminogen activator inhibitor-1 9.5
spinesin 9.5
EIF-4E 9.5
gene trap ankyrin repeat 9.5
more...
Disease
Saddle PE 10.5
Coronary artery reocclusion 9.9
Vascular thoracic outlet syndrome 9.9
Systemic fibrinogenolysis 9.5
Corticosteroid-induced glaucoma 9.5
Subretinal hemorrhage 9.5
Acute transmural myocardial infarction 9.5
Livedo vasculitis 9.5
Pleural infection 9.3
Congenital dysfibrinogenemia 9.3
Pulmonary artery thrombosis 9.3
Brain Ischemia 9.2
Post MI 9.1
FENIB 9.1
PLAT 8.8
Livedoid vasculitis 8.8
Suprachoroidal hemorrhage 8.7
Acute coagulopathy 8.7
Acute Stroke 8.5
Embolic stroke 8.5
more...
Symptom
Upper back pain 8.9
Lower extremity weakness 8.5
Mental status changes 7.2
facial droop 7.1
finger pain 6.2
Livedoid 5.8
thoracic back pain 5.7
disturbed balance 5.6
neurological disability 4.8
localized edema 4.7
monoplegia 4.7
consciousness disturbance 4.4
hemiplegia 4.4
chest pain 4.1
dysarthria 4.0
arm weakness 3.9
livedo 3.7
exertional angina 3.5
functional recovery 3.5
non-productive cough 3.3
more...
Drug
Cyclotheonamide A 11.5
Pamiteplase 11.1
Prolyse 10.7
Lanoteplase 10.7
Monteplase 10.7
Desmoteplase 10.5
Activase 10.3
Alteplase 10.1
Alteplase 10.0
Alteplase 10.0
Actimmune 9.9
Tenecteplase 9.2
uPA 9.0
Trafermin 8.9
Streptokinase 8.8
Urokinase 8.5
Sibrafiban 8.3
Sulotroban 8.1
Hirulog 7.7
Ancrod 7.6
more...
Enzyme
tissue plasminogen activator 11.5
thrombin-activatable fibrinolysis inhibitor 9.3
kyotorphin synthetase 9.1
urokinase-type plasminogen activator 9.1
plasmin 8.9
complement subcomponent C1r 8.7
ancrod 8.1
NS protease 7.5
neuropsin 7.4
carboxypeptidase B 7.2
destabilase 7.2
fibrolase 7.0
neuropsin 7.0
thrombin 6.5
neurosin 6.4
CPN 6.0
clotting enzyme 6.0
thromboplastin 6.0
APC 6.0
macrophage elastase 5.9
more...
Compound
1,3,7-Trihydroxyxanthone 11.5
Promazine hydrochloride 9.5
Scolymoside 9.5
AEK 9.4
5-amino-2-naphthalenesulfonic acid 9.1
Plasmin 9.0
FCB 8.7
6-aminohexanoic acid 8.5
6-aminohexanoic acid 8.5
Ginkgolide C 8.5
N-methylpropanamide 8.0
diphenyl phosphonate 7.9
Ginkgolide J 7.9
Methacycline 7.8
Fibrinopeptide A 7.7
Piperlonguminine 7.7
FDP 7.6
Ginkgolide C 7.6
Fibrin 7.6
2,3-dinor-thromboxane 7.2
more...