Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.68 (tissue plasminogen activator)
11,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tissue plasminogen activator 6267
PLA 5663
plasminogen 2292
urokinase-type plasminogen activator 1827
plasminogen activator inhibitor-1 1612
fibrinogen 1300
plasminogen activator inhibitor 1281
tPA 1232
thrombin 1089
Sep 795
Plasminogen 443
von Willebrand factor 403
antithrombin III 342
prothrombin 341
PAI 298
Mol 285
protein C 273
u-PA 268
insulin 252
serine protease 244
more...
Disease
stroke 2228
acute myocardial infarction 695
myocardial infarction 560
ischemia 449
cancer 342
atherosclerosis 308
tumor 276
hypertension 269
cerebral ischemia 245
diabetes 240
pulmonary embolism 231
cardiovascular disease 182
SDS 176
melanoma 166
deep vein thrombosis 159
coronary artery disease 143
disseminated intravascular coagulation 122
cerebral infarction 114
obesity 107
coronary heart disease 102
more...
Symptom
chest pain 104
pain 95
angina 69
functional recovery 53
anesthesia 50
hypothermia 46
seizures 44
weakness 36
respiratory distress 32
hemiplegia 29
dyspnea 28
overweight 26
dysarthria 22
headache 18
abdominal pain 17
syncope 13
collapse 12
hyperoxia 11
nausea 11
spasm 11
more...
Drug
uPA 386
lysine 325
Cardiovasc 187
Alteplase 98
Streptokinase 91
Alteplase 91
Alteplase 88
Urokinase 79
DDAVP 43
Asn 43
DDAVP 42
TAT 32
Dermatol 30
nitroglycerin 24
Activase 22
Aprotinin 22
Gel 20
CSF 19
Dial 19
CaCl2 15
more...
Enzyme
tissue plasminogen activator 11311
urokinase-type plasminogen activator 2035
plasmin 1564
thrombin 1062
APC 359
thromboplastin 297
trypsin 184
kallikrein 109
mitogen-activated protein kinase 88
collagenase 69
elastase 67
renin 56
thrombin-activatable fibrinolysis inhibitor 55
protein kinase C 55
ACE 51
protein kinase 48
chymotrypsin 43
creatine kinase 42
peroxidase 42
ERK 41
more...
Compound
Dec 794
Clin 638
Cardiol 440
lysine 416
DNA 324
arginine 256
serine 251
glucose 232
sodium 218
oxygen 203
calcium 199
SDS 187
sulfate 154
acetate 151
Fibrin 148
Plasmin 146
prostacyclin 140
Fibrinogen 136
ADP 127
Thrombin 126
more...