Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.68 (
tissue plasminogen activator
)
11,311
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tissue plasminogen activator
6267
PLA
5663
plasminogen
2292
urokinase-type plasminogen activator
1827
plasminogen activator inhibitor-1
1612
fibrinogen
1300
plasminogen activator inhibitor
1281
tPA
1232
thrombin
1089
Sep
795
Plasminogen
443
von Willebrand factor
403
antithrombin III
342
prothrombin
341
PAI
298
Mol
285
protein C
273
u-PA
268
insulin
252
serine protease
244
more...
Disease
stroke
2228
acute myocardial infarction
695
myocardial infarction
560
ischemia
449
cancer
342
atherosclerosis
308
tumor
276
hypertension
269
cerebral ischemia
245
diabetes
240
pulmonary embolism
231
cardiovascular disease
182
SDS
176
melanoma
166
deep vein thrombosis
159
coronary artery disease
143
disseminated intravascular coagulation
122
cerebral infarction
114
obesity
107
coronary heart disease
102
more...
Symptom
chest pain
104
pain
95
angina
69
functional recovery
53
anesthesia
50
hypothermia
46
seizures
44
weakness
36
respiratory distress
32
hemiplegia
29
dyspnea
28
overweight
26
dysarthria
22
headache
18
abdominal pain
17
syncope
13
collapse
12
hyperoxia
11
nausea
11
spasm
11
more...
Drug
uPA
386
lysine
325
Cardiovasc
187
Alteplase
98
Streptokinase
91
Alteplase
91
Alteplase
88
Urokinase
79
DDAVP
43
Asn
43
DDAVP
42
TAT
32
Dermatol
30
nitroglycerin
24
Activase
22
Aprotinin
22
Gel
20
CSF
19
Dial
19
CaCl2
15
more...
Enzyme
tissue plasminogen activator
11311
urokinase-type plasminogen activator
2035
plasmin
1564
thrombin
1062
APC
359
thromboplastin
297
trypsin
184
kallikrein
109
mitogen-activated protein kinase
88
collagenase
69
elastase
67
renin
56
thrombin-activatable fibrinolysis inhibitor
55
protein kinase C
55
ACE
51
protein kinase
48
chymotrypsin
43
creatine kinase
42
peroxidase
42
ERK
41
more...
Compound
Dec
794
Clin
638
Cardiol
440
lysine
416
DNA
324
arginine
256
serine
251
glucose
232
sodium
218
oxygen
203
calcium
199
SDS
187
sulfate
154
acetate
151
Fibrin
148
Plasmin
146
prostacyclin
140
Fibrinogen
136
ADP
127
Thrombin
126
more...