Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.68 (
tissue plasminogen activator
)
11,311
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Functional analysis of regulatory elements in the human
tissue plasminogen activator
(
tPA
) gene showed that its promoter (-119/+169) is activated by UV irradiation in HeLa cells. We demonstrated here that the
AP-2 like
CCCCACCC sequence is involved in the UV-mediated activation and Sp1 binds to the sequence.
...
PMID:Identification of the UV-responsive sequence in the human tissue plasminogen activator gene. 1087 89
