Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.64 (
proteinase K
)
4,071
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
prion protein
398
prion
357
PrP
354
SDS
313
Sep
292
Mol
290
chymotrypsin
179
polypeptide
170
lipopolysaccharide
127
Proteinase
102
lysozyme
90
ATP
85
RNase
81
glycoprotein
79
membrane protein
74
endoplasmic reticulum
72
Gen
68
GSD
64
Pseudomonas
64
DNase
63
kit
56
DNase I
55
catalase
55
ATPase
53
serine protease
51
serum albumin
49
alkaline phosphatase
49
lipase
46
neuraminidase
42
microsomal
40
fused
39
synuclein
39
membrane-bound
39
NMR
37
RNase A
36
endonuclease
36
amylase
33
LPS
32
Trypsin
31
lectin
29
alpha-amylase
29
cytokine
26
integral membrane protein
26
collagen
25
lymphoid
23
PLA
22
collagenase
22
alpha-synuclein
22
fibronectin
22
peroxidase
21
TOF
21
casein
20
gut
20
PRNP
19
ESI
19
histone
19
DNA polymerase
19
insulin
19
ribonuclease A
19
tumor necrosis factor
18
p53
18
ADP
18
AMP
17
keratin
17
Met
17
thrombin
17
NADH
17
PEG
16
thymus
16
hyaluronidase
16
Polymerase
16
lactoferrin
15
glucosamine
15
dimeric
15
fibrinogen
15
Prion protein
15
ubiquitin
15
albumin
14
35 kDa
14
phospholipase A2
14
more...
Disease
SDS
313
scrapie
241
Creutzfeldt-Jakob disease
111
cancer
95
spongiform encephalopathy
85
tumor
69
Parkinson's disease
59
Alzheimer's disease
49
neuroblastoma
39
Mycobacterium
36
HIV
35
Mycoplasma
31
dementia
27
tuberculosis
26
BSE
26
CJD
26
Gerstmann
26
immunodeficiency
24
Haemophilus
22
cold
22
infectious diseases
21
hepatitis B
20
leukemia
18
plaque
18
wasting
17
periodontitis
16
carcinoma
16
cholera
15
Chlamydia
15
hepatitis C
15
influenza
14
melanoma
14
hepatocellular carcinoma
14
Infection
13
Yersinia
13
carcinogenesis
12
cytomegalovirus
12
breast cancer
12
Legionella
11
MCF
11
herpes simplex
11
gastroenteritis
11
leptospirosis
11
worms
10
cervical cancer
10
Lyme disease
10
pertussis
10
uterus
10
pneumonia
10
Brucella abortus
10
multiple myeloma
10
Bordetella
10
hepatitis A
10
Schistosoma mansoni
9
MRS
9
kuru
9
vaccinia
9
Dementia with Lewy bodies
8
adenocarcinoma
8
gonococcal
8
hepatitis
8
dehydration
8
Klebsiella
8
cystic fibrosis
8
Epstein
8
syphilis
8
Proteus
8
FFI
8
malaria
7
virus infection
7
arthritis
7
encephalitis
7
TEM
7
vCJD
7
diabetes
7
squamous cell carcinoma
7
AIDS
7
ICP
6
sepsis
6
fungal infection
6
more...
Symptom
diarrhea
10
ataxia
10
insomnia
9
starvation
9
tremor
8
collapse
5
myoclonus
4
sleepiness
3
agitation
3
Ill
2
acidity
2
microbial colonization
2
splenomegaly
2
POA
1
flushing
1
halitosis
1
pain
1
bradykinesia
1
headache
1
eds
1
seizures
1
male subfertility
1
HSA
1
pallor
1
paraparesis
1
cachexia
1
erythema
1
No adverse effect
1
memory loss
1
nausea
1
cerebellar ataxia
1
vertigo
1
Drug
lysine
69
DNase I
56
Pronase
29
Gel
26
Asn
21
NADH
18
IFN-gamma
13
Bifidobacterium
12
ABC
11
ampicillin
7
lactose
7
IL-2
6
Dermatol
6
NaI
5
Ethanol
5
NaI
5
NaI
5
NH3
5
CSF
5
NaI
5
Papain
5
CaCl2
4
CaCl2
4
Alanine
4
Nephron
4
Mutagen
4
ascorbate
4
citric acid
4
CaCl2
4
NBT
3
ZnCl2
3
PCP
3
Glycerol
3
NAG
3
Paraffin
3
MRC
3
ZnCl2
3
FLP
3
Biopolymers
3
MAP
3
L-tyrosine
2
Sodium carbonate
2
FAD
2
SBT
2
Fragment
2
nitroglycerin
2
Fraction
2
DBS
2
Asparaginase
2
ZnO
2
Leaf
2
Adenosine triphosphate
1
RFP
1
Onconase
1
Dial
1
Albumin
1
Ammonium chloride
1
Celsis
1
Parkin
1
FeCl3
1
CIA
1
CTX
1
balanced salt solution
1
KAN
1
CrCl3
1
CFS
1
IPM
1
MDM
1
SiO2
1
Fructose
1
Growth hormone
1
Gelatin
1
Alliance
1
Hypaque
1
Rasburicase
1
Indomethacin
1
PPA
1
Ouabain
1
L-Asparaginase
1
Ethylenediamine
1
more...
Enzyme
proteinase K
4071
trypsin
547
chymotrypsin
225
subtilisin
162
RNase
143
pepsin
112
RNase
111
papain
97
lysozyme
90
DNase
82
elastase
57
catalase
56
ATPase
54
alkaline phosphatase
49
lipase
46
thermolysin
46
neuraminidase
44
endonuclease
36
phospholipase C
31
peroxidase
30
alpha-amylase
29
ribonuclease
27
ribonuclease
27
collagenase
25
micrococcal nuclease
21
DNA polymerase
21
reverse transcriptase
21
hyaluronidase
21
RNA polymerase
20
protein kinase
19
proteasome
19
phospholipase A2
19
thrombin
17
endoglycosidase H
16
topoisomerase
16
hyaluronidase
16
thermitase
15
topoisomerase
15
ERK
15
plasmin
14
neutrophil elastase
14
mitogen-activated protein kinase
13
chondroitinase
13
glutathione S-transferase
13
SPC
13
S1 nuclease
13
bromelain
13
superoxide dismutase
13
chondroitinase
12
chitinase
12
carboxypeptidase Y
11
acetylcholinesterase
11
deoxyribonuclease
11
protein kinase C
10
glyceraldehyde-3-phosphate dehydrogenase
10
RNase T1
9
ACS
9
deoxyribonuclease
9
CD10
9
cellulase
9
dihydrofolate reductase
9
endoproteinase Glu-C
9
caspase-3
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
cathepsin B
8
lactate dehydrogenase
8
proprotein convertase
7
acyl-CoA oxidase
7
APC
7
creatine kinase
7
xylanase
7
heparinase
7
transcriptase
7
xylanase
7
lipoprotein lipase
6
tyrosine hydroxylase
6
furin
6
more...
Compound
DNA
922
sodium
404
SDS
335
Dec
299
sulfate
286
phenol
236
chloroform
180
water
177
Clin
131
ethanol
124
serine
120
Triton X-100
113
EDTA
101
lysine
101
EDTA
100
calcium
99
ammonium
87
salt
86
ATP
85
alanine
82
urea
81
cysteine
78
hydrogen
77
methionine
77
phosphate
75
bromide
68
leucine
66
galactose
65
silver
63
arginine
57
tyrosine
54
guanidine
53
Tris
53
methanol
52
oxygen
51
glucose
50
His
49
Phe
48
HCl
48
Tris
47
iron
45
formaldehyde
42
Gly
40
nitrogen
39
acetate
39
PEG
39
threonine
37
copper
37
DEAE
34
Ile
31
Trypsin
31
formaldehyde
30
NH2
28
PEG
27
tryptophan
27
tryptophan
26
carbonate
26
zinc
26
Mg2+
26
tryptophan
26
tryptophan
26
Asp
24
proline
23
isopropanol
23
Congo red
22
valine
22
PLA
21
TOF
21
glycerol
21
potassium
20
acetic acid
20
Tween 20
19
formic acid
19
formic acid
19
ADP
19
formic acid
19
formic acid
19
formic acid
19
formic acid
19
formic acid
19
more...