Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.64 (
proteinase K
)
4,071
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
prion protein
398
prion
357
PrP
354
SDS
313
Sep
292
Mol
290
chymotrypsin
179
polypeptide
170
lipopolysaccharide
127
Proteinase
102
lysozyme
90
ATP
85
RNase
81
glycoprotein
79
membrane protein
74
endoplasmic reticulum
72
Gen
68
Pseudomonas
64
GSD
64
DNase
63
kit
56
DNase I
55
catalase
55
ATPase
53
serine protease
51
alkaline phosphatase
49
serum albumin
49
lipase
46
neuraminidase
42
microsomal
40
synuclein
39
membrane-bound
39
fused
39
NMR
37
RNase A
36
endonuclease
36
amylase
33
LPS
32
Trypsin
31
alpha-amylase
29
more...
Disease
SDS
313
scrapie
241
Creutzfeldt-Jakob disease
111
cancer
95
spongiform encephalopathy
85
tumor
69
Parkinson's disease
59
Alzheimer's disease
49
neuroblastoma
39
Mycobacterium
36
HIV
35
Mycoplasma
31
dementia
27
CJD
26
tuberculosis
26
Gerstmann
26
BSE
26
immunodeficiency
24
Haemophilus
22
cold
22
infectious diseases
21
hepatitis B
20
leukemia
18
plaque
18
wasting
17
carcinoma
16
periodontitis
16
hepatitis C
15
cholera
15
Chlamydia
15
hepatocellular carcinoma
14
melanoma
14
influenza
14
Yersinia
13
Infection
13
breast cancer
12
cytomegalovirus
12
carcinogenesis
12
leptospirosis
11
gastroenteritis
11
more...
Symptom
diarrhea
10
ataxia
10
insomnia
9
starvation
9
tremor
8
collapse
5
myoclonus
4
sleepiness
3
agitation
3
Ill
2
acidity
2
microbial colonization
2
splenomegaly
2
POA
1
flushing
1
halitosis
1
pain
1
bradykinesia
1
headache
1
eds
1
seizures
1
male subfertility
1
HSA
1
pallor
1
paraparesis
1
cachexia
1
erythema
1
No adverse effect
1
memory loss
1
nausea
1
cerebellar ataxia
1
vertigo
1
Drug
lysine
69
DNase I
56
Pronase
29
Gel
26
Asn
21
NADH
18
IFN-gamma
13
Bifidobacterium
12
ABC
11
ampicillin
7
lactose
7
Dermatol
6
IL-2
6
CSF
5
Ethanol
5
NaI
5
NaI
5
NaI
5
Papain
5
NaI
5
NH3
5
CaCl2
4
ascorbate
4
Mutagen
4
citric acid
4
Alanine
4
Nephron
4
CaCl2
4
CaCl2
4
FLP
3
NBT
3
Glycerol
3
PCP
3
Biopolymers
3
NAG
3
Paraffin
3
ZnCl2
3
MRC
3
ZnCl2
3
MAP
3
more...
Enzyme
proteinase K
4071
trypsin
547
chymotrypsin
225
subtilisin
162
RNase
143
pepsin
112
RNase
111
papain
97
lysozyme
90
DNase
82
elastase
57
catalase
56
ATPase
54
alkaline phosphatase
49
lipase
46
thermolysin
46
neuraminidase
44
endonuclease
36
phospholipase C
31
peroxidase
30
alpha-amylase
29
ribonuclease
27
ribonuclease
27
collagenase
25
DNA polymerase
21
reverse transcriptase
21
micrococcal nuclease
21
hyaluronidase
21
RNA polymerase
20
protein kinase
19
phospholipase A2
19
proteasome
19
thrombin
17
topoisomerase
16
endoglycosidase H
16
hyaluronidase
16
topoisomerase
15
ERK
15
thermitase
15
neutrophil elastase
14
more...
Compound
DNA
922
sodium
404
SDS
335
Dec
299
sulfate
286
phenol
236
chloroform
180
water
177
Clin
131
ethanol
124
serine
120
Triton X-100
113
lysine
101
EDTA
101
EDTA
100
calcium
99
ammonium
87
salt
86
ATP
85
alanine
82
urea
81
cysteine
78
methionine
77
hydrogen
77
phosphate
75
bromide
68
leucine
66
galactose
65
silver
63
arginine
57
tyrosine
54
Tris
53
guanidine
53
methanol
52
oxygen
51
glucose
50
His
49
HCl
48
Phe
48
Tris
47
more...