Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.64 (
proteinase K
)
4,071
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
prion protein
398
prion
357
PrP
354
SDS
313
Sep
292
Mol
290
chymotrypsin
179
polypeptide
170
lipopolysaccharide
127
Proteinase
102
lysozyme
90
ATP
85
RNase
81
glycoprotein
79
membrane protein
74
endoplasmic reticulum
72
Gen
68
GSD
64
Pseudomonas
64
DNase
63
kit
56
DNase I
55
catalase
55
ATPase
53
serine protease
51
serum albumin
49
alkaline phosphatase
49
lipase
46
neuraminidase
42
microsomal
40
fused
39
synuclein
39
membrane-bound
39
NMR
37
RNase A
36
endonuclease
36
amylase
33
LPS
32
Trypsin
31
alpha-amylase
29
lectin
29
integral membrane protein
26
cytokine
26
collagen
25
lymphoid
23
fibronectin
22
PLA
22
alpha-synuclein
22
collagenase
22
TOF
21
peroxidase
21
gut
20
casein
20
DNA polymerase
19
PRNP
19
ribonuclease A
19
insulin
19
histone
19
ESI
19
tumor necrosis factor
18
p53
18
ADP
18
Met
17
keratin
17
thrombin
17
NADH
17
AMP
17
hyaluronidase
16
Polymerase
16
thymus
16
PEG
16
fibrinogen
15
ubiquitin
15
lactoferrin
15
Prion protein
15
glucosamine
15
dimeric
15
phospholipase A2
14
28 kDa
14
cytochrome c
14
transferrin
14
35 kDa
14
IL-8
14
beta-globin
14
albumin
14
TLR2
14
phosphatidylinositol-specific
14
amyloid precursor protein
13
IFN-gamma
13
THP
13
PBS
13
TNF
13
superoxide dismutase
13
precursor protein
13
spermatozoa
13
surface antigen
13
CD4
13
chitinase
12
proteasome
12
tRNA
12
IL-6
12
chondroitinase
12
peptidase
11
acetylcholinesterase
11
NADPH
11
serine protease inhibitor
11
phosphatase
11
cytochrome
11
GTP
11
ABC
11
C18
11
interferon
11
transmembrane protein
11
HEK
11
H. influenzae
11
hemoglobin
11
threonine
10
tumor necrosis factor alpha
10
cryptic
10
unknown function
10
TLR4
10
porin
10
deoxyribonuclease
10
protease inhibitor
10
telomeric
10
CD8
10
IL-10
10
ribonucleoprotein
9
neutrophil elastase
9
MOLT
9
IgE
9
dihydrofolate reductase
9
caspase-3
9
Poly
9
NAD
9
ACS
9
MRS
9
mucin
9
CD14
9
apoE
9
galactosamine
9
plasminogen
9
esterase
9
Ca2+-ATPase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glial fibrillary acidic protein
8
brush border
8
olfactory
8
beta-actin
8
reductase
8
cytochrome c oxidase
8
proteoglycan
8
glutathione S-transferase
8
glucan
8
mer
8
interleukin-6
8
lactate dehydrogenase
8
membrane glycoprotein
8
mast cell
8
cathepsin B
8
more...
Disease
SDS
313
scrapie
241
Creutzfeldt-Jakob disease
111
cancer
95
spongiform encephalopathy
85
tumor
69
Parkinson's disease
59
Alzheimer's disease
49
neuroblastoma
39
Mycobacterium
36
HIV
35
Mycoplasma
31
dementia
27
Gerstmann
26
BSE
26
tuberculosis
26
CJD
26
immunodeficiency
24
Haemophilus
22
cold
22
infectious diseases
21
hepatitis B
20
leukemia
18
plaque
18
wasting
17
periodontitis
16
carcinoma
16
cholera
15
hepatitis C
15
Chlamydia
15
influenza
14
hepatocellular carcinoma
14
melanoma
14
Yersinia
13
Infection
13
cytomegalovirus
12
carcinogenesis
12
breast cancer
12
Legionella
11
herpes simplex
11
MCF
11
leptospirosis
11
gastroenteritis
11
multiple myeloma
10
pertussis
10
Bordetella
10
pneumonia
10
hepatitis A
10
cervical cancer
10
uterus
10
Brucella abortus
10
worms
10
Lyme disease
10
kuru
9
MRS
9
vaccinia
9
Schistosoma mansoni
9
adenocarcinoma
8
Proteus
8
hepatitis
8
gonococcal
8
dehydration
8
Dementia with Lewy bodies
8
Epstein
8
Klebsiella
8
syphilis
8
FFI
8
cystic fibrosis
8
diabetes
7
vCJD
7
arthritis
7
encephalitis
7
virus infection
7
squamous cell carcinoma
7
AIDS
7
malaria
7
TEM
7
ICP
6
fungal infection
6
sepsis
6
Adhesion
6
mastitis
6
obesity
6
Shigella flexneri
6
TEM
6
amyotrophic lateral sclerosis
6
lymphoma
6
CEM
6
depression
5
parvovirus
5
PCL
5
stomatitis
5
PCP
5
spotted fever
5
sepsis
5
encephalopathy
5
GSH
5
Cryptococcus neoformans
5
amyloidosis
5
candidiasis
5
CAA
5
ovarian cancer
5
Shiga
5
periodontal disease
5
mental illness
4
pseudotuberculosis
4
myopathy
4
multiple sclerosis
4
Dissociation
4
epithelial ovarian cancer
4
rheumatoid arthritis
4
viremia
4
schizophrenia
4
melioidosis
4
vascular disease
4
meningitis
4
cognitive impairment
4
Shigella
4
atherosclerosis
4
ischemia
4
endocarditis
4
gastritis
4
cornea
4
conversion reaction
4
neurological disease
4
hypercholesterolemia
4
colon cancer
4
Gaucher disease
4
acute myeloid leukemia
4
colorectal cancer
4
fibrosarcoma
4
parkinsonism
4
tumor growth
4
abdominal aortic aneurysm
4
SEM
4
osteomyelitis
3
human papilloma virus
3
human papilloma virus
3
AAA
3
STS
3
LAP
3
SARS
3
toxoplasmosis
3
osteoarthritis
3
leishmaniasis
3
CAP
3
scrub typhus
3
volvulus
3
APC
3
long QT syndrome
3
MRSA
3
leprosy
3
dengue
3
vagina
3
PCC
3
dental caries
3
hyperglycemia
3
Spleen
3
Newcastle disease
3
urethritis
3
more...
Symptom
diarrhea
10
ataxia
10
insomnia
9
starvation
9
tremor
8
collapse
5
myoclonus
4
sleepiness
3
agitation
3
Ill
2
acidity
2
microbial colonization
2
splenomegaly
2
POA
1
flushing
1
halitosis
1
pain
1
bradykinesia
1
headache
1
eds
1
seizures
1
male subfertility
1
HSA
1
pallor
1
paraparesis
1
cachexia
1
erythema
1
No adverse effect
1
memory loss
1
nausea
1
cerebellar ataxia
1
vertigo
1
Drug
lysine
69
DNase I
56
Pronase
29
Gel
26
Asn
21
NADH
18
IFN-gamma
13
Bifidobacterium
12
ABC
11
ampicillin
7
lactose
7
Dermatol
6
IL-2
6
Papain
5
Ethanol
5
NaI
5
NaI
5
CSF
5
NH3
5
NaI
5
NaI
5
citric acid
4
Alanine
4
CaCl2
4
Nephron
4
Mutagen
4
ascorbate
4
CaCl2
4
CaCl2
4
ZnCl2
3
Glycerol
3
PCP
3
NAG
3
ZnCl2
3
Biopolymers
3
FLP
3
Paraffin
3
NBT
3
MRC
3
MAP
3
DBS
2
L-tyrosine
2
FAD
2
SBT
2
Leaf
2
ZnO
2
Asparaginase
2
Fraction
2
Fragment
2
nitroglycerin
2
Sodium carbonate
2
CoCl2
1
Onconase
1
mepivacaine hydrochloride
1
Dial
1
Albumin
1
Ammonium chloride
1
Iodixanol
1
Adenosine triphosphate
1
RFP
1
Parkin
1
FeCl3
1
CIA
1
CFS
1
CTX
1
balanced salt solution
1
KAN
1
CrCl3
1
Polaprezinc
1
Growth hormone
1
MDM
1
Fluorescein
1
SiO2
1
Fructose
1
Cardiovasc
1
IPM
1
Ouabain
1
Lugol
1
Alliance
1
Hypaque
1
Parkin
1
Rasburicase
1
Indomethacin
1
PPA
1
DFP
1
Gelatin
1
AZT
1
Hyaluronidase
1
L-Asparaginase
1
Spectrum
1
FSH-beta
1
Ethylenediamine
1
DHT
1
Angiotensin II
1
Ddc
1
uPA
1
Furan
1
Ranitidine
1
Vitamin E
1
Growth hormone
1
Glutathione
1
Itraconazole
1
Acetic Acid
1
C14H16O2
1
FSH-beta
1
Hyaluronidase
1
Meth
1
Fluorescein
1
all-trans-retinol
1
vitamin E
1
Acacia
1
Diamminedichloroplatinum
1
Taxol
1
Azacytidine
1
Doyle
1
ISP
1
IL-1ra
1
Ginseng
1
AZT
1
-deoxyadenosine
1
FSH-beta
1
CoCl2
1
Celsis
1
Heme
1
Giardiasis
1
BoNT/A
1
K-252a
1
Maltose
1
Etoposide
1
Hypaque
1
Honey
1
TAK
1
Enzyme
proteinase K
4071
trypsin
547
chymotrypsin
225
subtilisin
162
RNase
143
pepsin
112
RNase
111
papain
97
lysozyme
90
DNase
82
elastase
57
catalase
56
ATPase
54
alkaline phosphatase
49
lipase
46
thermolysin
46
neuraminidase
44
endonuclease
36
phospholipase C
31
peroxidase
30
alpha-amylase
29
ribonuclease
27
ribonuclease
27
collagenase
25
micrococcal nuclease
21
reverse transcriptase
21
hyaluronidase
21
DNA polymerase
21
RNA polymerase
20
protein kinase
19
proteasome
19
phospholipase A2
19
thrombin
17
topoisomerase
16
endoglycosidase H
16
hyaluronidase
16
thermitase
15
topoisomerase
15
ERK
15
neutrophil elastase
14
plasmin
14
superoxide dismutase
13
mitogen-activated protein kinase
13
S1 nuclease
13
glutathione S-transferase
13
bromelain
13
chondroitinase
13
SPC
13
chitinase
12
chondroitinase
12
carboxypeptidase Y
11
acetylcholinesterase
11
deoxyribonuclease
11
glyceraldehyde-3-phosphate dehydrogenase
10
protein kinase C
10
ACS
9
CD10
9
dihydrofolate reductase
9
deoxyribonuclease
9
RNase T1
9
endoproteinase Glu-C
9
cellulase
9
lactate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
cathepsin B
8
caspase-3
8
glyceraldehyde-3-phosphate dehydrogenase
8
proprotein convertase
7
transcriptase
7
xylanase
7
APC
7
heparinase
7
acyl-CoA oxidase
7
creatine kinase
7
xylanase
7
lipoprotein lipase
6
transglutaminase
6
PNGase F
6
cathepsin G
6
furin
6
tyrosine hydroxylase
6
RNase P
5
CD13
5
luciferase
5
thromboplastin
5
pectinase
5
beta-lactamase
5
beta-galactosidase
5
proteinase A
5
KAT
5
CPT
5
glucocerebrosidase
5
tyrosinase
5
kallikrein
5
phosphodiesterase
5
lysostaphin
5
glycoprotease
4
carboxypeptidase A
4
deaminase
4
urokinase-type plasminogen activator
4
cystathionine gamma-lyase
4
polynucleotide kinase
4
alpha-mannosidase
4
uricase
4
acid phosphatase
4
enolase
4
Thy1
4
PRA
4
cathepsin L
4
NADPH oxidase
4
ricin
4
NADPH oxidase
4
aspartate aminotransferase
4
glutathione peroxidase
4
transhydrogenase
4
arginine deiminase
4
beta-glucuronidase
4
beta-1,3-glucanase
4
beta-1,3-glucanase
4
mannanase
4
lysyl endopeptidase
3
alpha-glucosidase
3
ATP synthase
3
asparaginase
3
neuropathy target esterase
3
lambda exonuclease
3
Fpg protein
3
caspase-9
3
thymidine kinase
3
apyrase
3
mu-calpain
3
carboxylesterase
3
pyruvate dehydrogenase
3
caspase-1
3
cathepsin D
3
ficin
3
Pla
3
endo-beta-galactosidase
3
calcineurin
3
TdT
3
ACE
3
proteinase A
3
hexosaminidase
3
malate dehydrogenase
3
pullulanase
3
pyruvate dehydrogenase
3
chaperonin
3
pyruvate dehydrogenase
3
laccase
3
3'-exonuclease
3
PCP
3
aldolase
3
RNase H
3
beta-amylase
2
5'-nucleotidase
2
chloramphenicol acetyltransferase
2
CPT
2
beta-glucosidase
2
more...
Compound
DNA
922
sodium
404
SDS
335
Dec
299
sulfate
286
phenol
236
chloroform
180
water
177
Clin
131
ethanol
124
serine
120
Triton X-100
113
lysine
101
EDTA
101
EDTA
100
calcium
99
ammonium
87
salt
86
ATP
85
alanine
82
urea
81
cysteine
78
hydrogen
77
methionine
77
phosphate
75
bromide
68
leucine
66
galactose
65
silver
63
arginine
57
tyrosine
54
guanidine
53
Tris
53
methanol
52
oxygen
51
glucose
50
His
49
Phe
48
HCl
48
Tris
47
iron
45
formaldehyde
42
Gly
40
PEG
39
acetate
39
nitrogen
39
threonine
37
copper
37
DEAE
34
Ile
31
Trypsin
31
formaldehyde
30
NH2
28
tryptophan
27
PEG
27
tryptophan
26
tryptophan
26
zinc
26
Mg2+
26
carbonate
26
tryptophan
26
Asp
24
isopropanol
23
proline
23
Congo red
22
valine
22
glycerol
21
PLA
21
TOF
21
acetic acid
20
potassium
20
formic acid
19
acetone
19
formic acid
19
formic acid
19
formic acid
19
ADP
19
formic acid
19
formic acid
19
Tween 20
19
formic acid
19
formic acid
19
formic acid
19
formic acid
19
ADP
18
CTAB
18
AMP
18
GlcNAc
18
NADH
18
ADP
18
hydroxide
18
Tween 80
17
H2O2
17
asparagine
16
formamide
16
glutamine
16
ammonia
15
acetonitrile
15
dUTP
15
glutamic acid
15
2-mercaptoethanol
15
PMSF
14
octyl
13
octyl
13
THP
13
KOH
13
THP
13
glutamate
13
octyl
13
TNF
13
Optimal
12
iodine
12
manganese
12
acrylamide
12
Triton
12
CHAPS
12
isoleucine
12
isoleucine
12
GTP
12
xylose
11
nitric oxide
11
NADPH
11
NADPH
11
DMSO
10
sodium chloride
10
MTT
10
TCA
10
DSM
10
NAD
10
MgCl2
10
COS
10
ClO
9
uridine
9
nitrate
9
ACS
9
ACS
9
NAD
9
GalNAc
9
aspartic acid
8
TTP
8
pyridine
8
DTT
8
Guo
8
DTT
8
UTP
7
palmitic acid
7
Serine
7
CO2
7
chromate
7
aspartic acid
7
aspartic acid
7
UDP
7
Cyt
7
Lactate
7
Lactic acid
7
palmitic acid
7
aldehyde
7
aspartic acid
7
aluminum
7
selenium
7
more...