Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.6 (thromboplastin)
13,278 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thromboplastin 8139
factor Xa 5162
prothrombin 4735
thrombin 4498
fibrinogen 2136
antithrombin 927
antithrombin III 877
tissue factor 861
Sep 838
factor VIII 785
protein C 505
factor VII 505
thrombin inhibitor 474
factor V 464
VIII 406
collagen 401
Prothrombin 396
tissue factor pathway inhibitor 339
von Willebrand factor 324
plasminogen 322
factor IX 301
PLA 266
hemoglobin 259
protein S 253
serine protease 239
ADP 209
thrombomodulin 178
albumin 175
Mol 173
SDS 170
glycoprotein 168
dilute 167
hemophilia A 166
factor XI 165
tissue plasminogen activator 165
Factor VIII 161
factor XII 156
urokinase-type plasminogen activator 141
She 138
heavy chain 137
FVIII 134
heparin cofactor II 128
plasminogen activator inhibitor 119
kallikrein 117
NMR 114
chymotrypsin 112
lipopolysaccharide 107
polypeptide 104
platelet factor 4 97
plasminogen activator inhibitor-1 95
annexin V 93
bradykinin 91
tumor necrosis factor 90
aspartate aminotransferase 89
alkaline phosphatase 85
C-reactive protein 78
fused 76
alanine aminotransferase 76
membrane-bound 74
serum albumin 73
cytokine 67
trypsin inhibitor 67
X mRNA 66
serine protease inhibitor 64
TNF 64
Antithrombin 63
FIX 63
lactate dehydrogenase 63
factor V Leiden 62
protease inhibitor 62
Protein C 62
EPI 60
coagulation factor VIII 59
GPIIb 56
coagulation factor X 54
P-selectin 53
FDP 53
epidermal growth factor 49
Hageman factor 47
insulin 47
LPS 46
Factor IX 46
alpha 2-plasmin inhibitor 46
Antithrombin III 45
DIC 45
plasma prekallikrein 44
apoE 43
Protein S 43
vWF 43
Pol 43
IL-6 41
Plasminogen 41
vascular endothelium 41
APC 39
coagulation factor V 38
glycoprotein IIb 38
beta-thromboglobulin 38
FXI 38
beta2-glycoprotein I 37
interleukin-6 37
STA 36
phospholipase A2 36
cytochrome P450 35
PCI 35
thrombin receptor 34
platelet-derived 34
esterase 33
protein Z-dependent protease inhibitor 33
ATP 33
Factor XII 33
alpha 1-antitrypsin 32
intrinsic factor 31
PAR-2 31
ACS 31
fibronectin 30
neutrophil elastase 30
P-glycoprotein 30
protein Z 29
HDL 28
creatine kinase 28
ACL 27
cathepsin G 26
chronic renal failure 26
SAR 26
white cell 25
granulocyte 24
Plasmin 23
cage 23
ASA 23
IgA 23
serine proteinase inhibitor 22
ACT 22
Fibrinogen-like protein 2 22
PAR1 22
Thrombomodulin 21
tPA 21
TNF-alpha 21
kit 21
Mal 21
P2Y12 21
glucosamine 21
TAT 20
PAR-1 20
Gen 20
KOP 20
LDH 19
coagulation factor IX 19
arginine vasopressin 19
membrane protein 19
GPI 19
lipoprotein lipase 19
IL-8 19
coagulation factor VII 18
CD62P 18
alpha2-macroglobulin 18
effector cell protease receptor-1 18
Met 18
interferon 18
urinary kallikrein 18
metalloprotease 18
more...
Disease
thrombocytopenia 630
systemic lupus erythematosus 596
stroke 590
disseminated intravascular coagulation 571
lupus 544
coagulopathy 518
lupus 484
deep vein thrombosis 390
cancer 369
haemophilia 325
pulmonary embolism 272
Haemophilia 270
sepsis 197
myocardial infarction 179
SDS 170
sepsis 169
antiphospholipid syndrome 155
tumor 154
anemia 126
von Willebrand disease 122
liver disease 107
hypertension 105
atherosclerosis 100
diabetes 98
acute myocardial infarction 98
Lupus 97
Acquired hemophilia 83
ischemia 81
hemophilia B 80
renal failure 78
Thrombus 73
cirrhosis 72
abortion 67
unstable angina 65
cardiovascular disease 63
renal impairment 62
coronary artery disease 58
hepatitis 58
heart failure 52
plaque 51
carcinoma 51
renal disease 50
autoimmune disease 47
SEM 47
vitamin K deficiency 47
HIV 46
renal insufficiency 45
hemorrhagic diathesis 45
virus infection 45
preeclampsia 44
leukemia 44
cold 44
hepatocellular carcinoma 43
hypofibrinogenemia 41
depression 40
hemolytic anemia 40
obesity 39
myocardial ischemia 39
APC 39
pneumonia 38
coma 38
proteinuria 38
leukopenia 37
hypoprothrombinemia 36
Heparin-induced thrombocytopenia 34
infectious diseases 34
cerebral ischemia 33
multiple myeloma 33
metastases 32
lymphoma 32
acute renal failure 32
coronary thrombosis 32
cerebral infarction 30
chronic renal failure 30
thrombocytosis 30
immunodeficiency 29
respiratory failure 29
dengue 28
coronary heart disease 28
purpura 27
venous stasis 27
vascular disease 26
SAR 26
nephrotic syndrome 26
glomerulonephritis 26
fits 25
syphilis 24
Owren 24
hyperlipidemia 23
pulmonary hypertension 23
vasculitis 23
adenocarcinoma 23
thrombocytopenic purpura 23
breast cancer 22
melanoma 22
chronic liver disease 22
heart disease 22
pancreatitis 22
osteoporosis 21
DVT 21
rare disease 21
lung cancer 21
Thrombophilia 21
acute promyelocytic leukemia 21
adult respiratory distress syndrome 20
SARS 20
peritonitis 20
petechiae 20
rash 20
acute lymphoblastic leukemia 19
arthritis 19
lymphopenia 19
Best 19
hepatitis B 19
cytomegalovirus 19
Brown 19
Rosenthal 19
SLE 19
type 2 diabetes 18
endocarditis 18
viral hepatitis 18
Fibrillation 18
West 18
tumor growth 18
Glanzmann's thrombasthenia 17
Infection 17
transient ischemic attack 16
hypoglycemia 16
rheumatoid arthritis 16
PCC 16
pheochromocytoma 16
hemiparesis 16
Fletcher trait 15
myeloproliferative disorders 15
circulating anticoagulants 15
mole 15
malaria 15
hyperglycemia 15
Alzheimer's disease 15
neutropenia 15
osteoarthritis 15
mole 15
subarachnoid hemorrhage 15
AIDS 15
asthma 14
prostate cancer 14
malnutrition 14
congestive heart failure 14
GSH 14
hypercholesterolemia 14
hemorrhagic fever 14
amyloidosis 14
confusion 14
dysfibrinogenemia 14
platelet disorder 14
MCF 14
thrombophlebitis 13
acute myeloid leukemia 13
leeches 13
sickle cell disease 13
more...
Symptom
anesthesia 131
pain 72
abdominal pain 53
diarrhea 46
vomiting 43
hypothermia 41
dyspnea 37
respiratory distress 35
headache 35
weakness 29
nausea 27
angina 25
fatigue 24
seizures 24
splenomegaly 21
anorexia 20
hepatomegaly 18
chest pain 18
cough 18
lethargy 16
Ill 16
hepatosplenomegaly 15
collapse 15
flushing 15
colic 14
hypoproteinemia 12
myalgia 12
tachypnea 11
pallor 11
livedo 10
analgesia 10
hemoptysis 9
nausea and vomiting 9
dizziness 9
discomfort 8
oliguria 8
discomfort 8
cyanosis 8
chills 8
exhaustion 7
erythema 7
arthralgia 6
hemiplegia 6
tremor 5
sleepiness 5
dysarthria 5
consciousness disturbance 5
paresis 5
overweight 5
exertional dyspnea 4
chorea 4
intestinal bleeding 4
shortness of breath 4
syncope 4
back pain 4
abdominal discomfort 4
HSA 3
low back pain 3
agitation 3
tense 3
constipation 3
paraparesis 3
epigastric pain 3
flank pain 3
paresthesia 3
sore throat 3
ataxia 3
regurgitation 3
functional recovery 2
ENT 2
polydipsia 2
Livedoid 2
menometrorrhagia 2
muscle rigidity 2
Respiratory symptoms 2
spasm 2
spasticity 2
dysuria 2
leg edema 2
presyncope 2
polyuria 2
cachexia 2
irregular bleeding 2
dark urine 2
hyperoxia 2
hypercapnia 2
tonic-clonic seizure 1
Sedation 1
decreased appetite 1
acute pain 1
urinary frequency 1
Organ failure 1
leg pain 1
acute abdominal pain 1
abnormal bruising 1
menopausal symptoms 1
bloating 1
labored breathing 1
non-productive cough 1
pleuritic chest pain 1
apathy 1
shoulder pain 1
CSR 1
epigastric distress 1
distraction 1
stomach pain 1
ovulatory bleeding 1
clonus 1
eds 1
acute abdomen 1
Decreased activity 1
abdominal cramps 1
arm pain 1
not coping 1
numbness 1
Todd's paralysis 1
otalgia 1
acute stress 1
Overlying 1
chronic back pain 1
stridor 1
Visual symptoms 1
Fluctuation 1
right upper quadrant pain 1
Mental status changes 1
fever of unknown origin 1
Urticarial vasculitis 1
Postoperative pain 1
tinnitus 1
loin pain 1
stuffy nose 1
heartburn 1
bradypnea 1
prostration 1
asthenia 1
arm weakness 1
staggering gait 1
acidity 1
chest tightness 1
pelvic pain 1
hip pain 1
twitching 1
hypertonia 1
hypotonia 1
nasal congestion 1
productive cough 1
neck stiffness 1
fussy infant 1
Drug
Cardiovasc 221
Fondaparinux 120
Apixaban 99
Vitamin K 90
lysine 72
CaCl2 64
CaCl2 63
CaCl2 63
PTC 55
LMWH 55
Argatroban 53
Antithrombin III 45
Dalteparin 44
Asn 36
Gel 33
Fragmin 30
EE2 27
Dermatol 26
Ximelagatran 24
ACT 22
ENT 22
TAT 20
RBT 20
uPA 19
nitroglycerin 19
DDAVP 18
PFA 18
Kaolin 17
DDAVP 16
Aprotinin 16
IL-2 15
Norplant 15
NovoSeven 15
Monit 14
Lepirudin 14
Phosphatidylserine 14
Bivalirudin 14
Protamine sulfate 14
Vitamin B12 13
FeCl3 13
Orgaran 13
Lovenox 13
Dial 12
Albumin 12
DFP 12
TAK 12
Clopidogrel 11
lactose 11
Hirulog 11
vitamin E 11
Hydroxyethylstarch 10
Fraction 10
CTX 10
ROC 10
MAP 10
Nephron 9
Norplant 9
EPI 9
Nephron 9
Fragment 8
Ringer's solution 7
Prednisolone 7
Thrombostat 7
Urokinase 7
ascorbate 7
Bayer 6
Coumadin 6
ABC 6
Prednisone 6
Streptokinase 6
Portal 5
Alteplase 5
IFN-gamma 5
EPA 5
Phenprocoumon 5
citric acid 4
Cangrelor 4
Leaf 4
NADH 4
Fluorescein 4
Rituximab 4
AHF 4
CSF 4
Abciximab 4
Alteplase 4
Heparin sodium 4
Alteplase 4
Pentastarch 4
DNase I 4
Fluorescein 4
Glutathione 3
Sodium dehydroacetate 3
Desirudin 3
Ketorolac 3
CFT 3
Ardeparin 3
Desmopressin acetate 3
Biopolymers 3
MgSO4 3
Retinoic acid 3
Isotretinoin 3
Calciparine 3
Levonorgestrel 3
Silica 3
LMOX 3
Serum albumin 3
CAM 3
ampicillin 3
Ancrod 3
Vitamin E 3
Simvastatin 3
Indomethacin 3
CTX 2
Vitamin A 2
CTX 2
Gabexate mesilate 2
Methylprednisolone 2
pyridoxal phosphate 2
ZnO 2
Napsagatran 2
Safflower 2
Itraconazole 2
Dakar 2
caffeine 2
CDP 2
ZnCl2 2
Maltose 2
NH3 2
Warfarin sodium 2
Eptifibatide 2
Iohexol 2
Bromelain 2
ALA 2
Helium 2
KGF 2
Angiotensin II 2
Cilostazol 2
Acacia 2
Nabumetone 2
Ethamsylate 2
Spectrum 2
Rutin 2
Perphenazine 2
ROS 2
Normiflo 2
Iloprost 2
Carbetimer 2
ZnCl2 2
Gamma globulin 1
Ethanol 1
CVA 1
CTC 1
IPD 1
VCR 1
CDX 1
Mezlocillin 1
Clivarine 1
Ketorolac tromethamine 1
Monensin 1
Iopromide 1
more...
Enzyme
thromboplastin 13278
thrombin 4505
APC 817
plasmin 370
trypsin 366
tissue plasminogen activator 297
kallikrein 196
urokinase-type plasminogen activator 150
chymotrypsin 131
alanine aminotransferase 116
aspartate aminotransferase 107
alkaline phosphatase 86
lactate dehydrogenase 75
elastase 64
heparinase 54
phospholipase A2 49
Hageman factor 47
neutrophil elastase 45
creatine kinase 40
mitogen-activated protein kinase 38
tissue kallikrein 35
phospholipase C 32
ACS 31
P-glycoprotein 30
peroxidase 28
ERK 27
papain 27
tryptase 26
cathepsin G 24
glutathione S-transferase 24
subtilisin 22
TAT 20
clotting enzyme 20
beta-galactosidase 19
asparaginase 19
lipoprotein lipase 19
catalase 18
protein kinase 17
protein kinase C 17
superoxide dismutase 17
deaminase 16
AST 15
collagenase 15
ACE 15
thrombin-activatable fibrinolysis inhibitor 14
CYP3A4 14
lipase 14
cancer procoagulant 14
gamma-glutamyl transpeptidase 13
enterokinase 13
acetylcholinesterase 13
phosphodiesterase 12
lysozyme 12
renin 10
neuraminidase 10
coagulation factor VIIa 10
luciferase 10
reverse transcriptase 10
thermolysin 9
cholinesterase 9
ATPase 9
focal adhesion kinase 8
pepsin 8
caspase-3 8
PTA 8
transglutaminase 8
coagulation factor XIa 8
matriptase 7
chymase 7
ceruloplasmin 7
matriptase 7
beta-glucuronidase 6
hyaluronidase 6
apyrase 6
CD10 6
RNase 6
lipoxygenase 6
thromboxane synthase 6
ficin 6
bromelain 6
sorbitol dehydrogenase 6
granzyme B 6
HIV-1 protease 5
dihydrofolate reductase 5
RVV-V 5
CAD 5
proteinase K 5
PNGase F 5
acid phosphatase 5
ancrod 5
CAD 5
CAD 5
ribonuclease 4
coagulation factor IXa 4
endonuclease 4
RNase 4
nucleotidase 4
phenylalanine hydroxylase 4
ribonuclease 4
UDP-glucuronosyltransferase 4
BAL 4
chondroitinase 4
RNA polymerase 4
glutamate dehydrogenase 4
NO synthase 4
thymidine kinase 4
MMP 4
TdT 4
TGT 4
chondroitinase 4
MAP 4
alpha-L-fucosidase 3
heme oxygenase 3
ornithine aminotransferase 3
factor C 3
PAH 3
methylenetetrahydrofolate reductase 3
AMPK 3
proteasome 3
methylenetetrahydrofolate reductase 3
C3 convertase 3
hepsin 3
cathepsin K 3
sialidase 3
5'-nucleotidase 3
caspase-1 3
alcohol oxidase 3
thyroid peroxidase 3
firefly luciferase 3
glutathione peroxidase 3
glutamate dehydrogenase 3
cathepsin B 3
hepsin 3
glutamate dehydrogenase 3
beta-lactamase 3
endoproteinase Glu-C 3
alcohol dehydrogenase 2
beta-secretase 2
S1 nuclease 2
cathepsin D 2
HSD 2
hyaluronidase 2
CPT 2
urease 2
TSR 2
carboxypeptidase B 2
acrosin 2
alpha-galactosidase 2
adenylate cyclase 2
lactic acid dehydrogenase 2
CPT 2
chondroitin ABC lyase 2
C1 esterase 2
cysteine dioxygenase 2
C3 convertase 2
Mg2+-ATPase 2
CPT 2
LPL 2
cathepsin C 2
lysyl endopeptidase 2
more...
Compound
Clin 1135
Dec 924
calcium 693
sulfate 504
Heparin 498
arginine 430
sodium 380
serine 359
Thrombin 347
ADP 310
ADP 215
DNA 211
ADP 209
water 202
creatinine 198
Cardiol 182
SDS 179
Gly 155
lysine 151
Fibrinogen 149
His 144
Warfarin 144
urea 135
glucose 134
alanine 133
Phe 119
oxygen 113
acetate 109
Factor X 103
nitrogen 98
Vitamin K 91
tyrosine 88
Asp 81
EDTA 80
Ile 79
hydrogen 78
cysteine 77
Fibrin 74
ASA 73
galactose 72
phosphate 69
EDTA 68
prostacyclin 68
leucine 67
DEAE 66
CaCl2 64
TNF 64
salt 61
ethanol 58
threonine 57
FDP 53
NH2 52
Argatroban 52
DIC 47
potassium 45
ammonium 44
PEG 43
nitric oxide 43
methionine 42
iron 39
zinc 35
ACS 34
barium 33
ATP 33
ACS 31
Optimal 31
PEG 30
bromide 28
glutamic acid 28
TEM 28
HCl 26
Protamine 26
copper 26
proline 26
glutamine 24
homocysteine 24
acetone 24
Plasmin 23
aspartic acid 23
pyridine 23
acetic acid 23
aspartic acid 22
tryptophan 22
MDA 22
aspartic acid 22
aspartic acid 22
tryptophan 21
tryptophan 21
tryptophan 21
xylose 19
COS 19
MTT 19
vinyl 19
aldehyde 18
acrylic acid 18
sodium chloride 18
prostaglandin E1 18
Dermatan sulfate 18
titanium 17
ammonia 17
Mg2+ 17
GSH 17
Organon 17
GSH 17
THP 17
THP 16
Estrogen 16
Serine 16
TEG 16
glutamate 16
Collagen 16
glycerol 16
hydroxide 16
piperidine 15
GalNAc 15
piperidine 15
methanol 15
asparagine 14
Phosphatidylserine 14
guanidine 14
Dextran 14
PMSF 14
C-3 14
Hemoglobin 14
manganese 13
Dermatan sulfate 13
phenol 13
Tris 13
TOF 13
sulfuric acid 12
PLA 12
nickel 12
iodine 12
phosphorus 12
Dial 12
carbonate 12
Trypsin 12
A 3 12
2-naphthyl 12
fluorine 12
TAP 11
valine 11
Heparan sulfate 11
aluminum 11
cAMP 11
Triton X-100 11
SO3 11
aldehyde 11
nitrous acid 11
Tris 11
salicylic acid 10
acrylamide 10
PGE2 10
Salt 10
CO2 10
A 42 10
Tranexamic acid 10
Sodium 10
APAP 10
CTX 10
more...