Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.6 (
thromboplastin
)
13,278
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
We describe the use of low doses of warfarin to treat
calcinosis
in a patient with systemic sclerosis or CREST syndrome. Our patient had Raynaud's phenomenon, skin sclerosis of the neck and the distal surface of the elbows, and pitting ulcers and scarification of the fingers as well as cutaneous
calcinosis
. After beginning warfarin, no calcium containing substance was discharged from the fingertip ulcers. There was no tendency to bleed and activated partial
thromboplastin
time and prothrombin time were normal. Sequential radiographs of the hands showed that
calcinosis
had improved. Since there seem to be few adverse effects, the use of warfarin in patients with
calcinosis
warrants further study.
...
PMID:The effects of warfarin on calcinosis in a patient with systemic sclerosis. 837 Dec 27
