Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.5 (thrombin)
 33,306 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thrombin 0.970
factor Xa 0.037
antithrombin 0.034
fibrinogen 0.033
prothrombin 0.029
antithrombin III 0.024
thrombin receptor 0.017
thromboplastin 0.016
thrombin inhibitor 0.015
tissue factor 0.013
thrombomodulin 0.012
protein C 0.009
heparin cofactor II 0.007
PAR-1 0.007
PAR1 0.005
factor V 0.004
ADP 0.004
PAR4 0.004
Thrombomodulin 0.003
protease-activated receptor-1 0.003
protease-activated receptor 1 0.003
GPIIb 0.003
von Willebrand factor 0.003
tissue factor pathway inhibitor 0.003
Prothrombin 0.003
plasminogen 0.002
serine protease 0.002
P-selectin 0.002
factor VII 0.002
Antithrombin 0.002
platelet factor 4 0.002
protein S 0.002
thrombin-activatable fibrinolysis inhibitor 0.002
collagen 0.002
factor VIII 0.002
Protein C 0.002
PAR-4 0.002
Heparin cofactor II 0.002
PLA 0.002
GPIb 0.001
plasminogen activator inhibitor 0.001
factor XI 0.001
tissue plasminogen activator 0.001
beta-thromboglobulin 0.001
glycoprotein IIb 0.001
CD62P 0.001
Antithrombin III 0.001
nexin 0.001
PAR-2 0.001
PAR2 0.001
urokinase-type plasminogen activator 0.001
plasminogen activator inhibitor-1 0.001
Thrombin receptor 0.001
alpha 2-plasmin inhibitor 0.001
PAR3 0.001
Fibrinopeptide A 0.001
factor XII 0.001
FXI 0.001
kallikrein 0.001
VIII 0.001
factor IX 0.001
glycoprotein VI 0.001
platelet-derived 0.001
endothelial protein C receptor 0.001
X mRNA 0.001
FVIII 0.001
PAR-3 0.001
factor XIIIa 0.001
chymotrypsin 0.001
Factor VIII 0.001
FDP 0.000
bradykinin 0.000
Plasmin 0.000
FIX 0.000
PAC-1 0.000
glycoprotein 0.000
protease-activated receptor 4 0.000
serine protease inhibitor 0.000
PAF 0.000
trypsin inhibitor 0.000
more...
Disease
disseminated intravascular coagulation 0.002
dysfibrinogenemia 0.001
coagulopathy 0.001
Glanzmann's thrombasthenia 0.000
thrombocytopenia 0.000
deep vein thrombosis 0.000
Heparin-induced thrombocytopenia 0.000
haemophilia 0.000
PAF 0.000
Thrombus 0.000
Bernard-Soulier syndrome 0.000
Haemophilia 0.000
Scott syndrome 0.000
SDS 0.000
hypofibrinogenemia 0.000
unstable angina 0.000
atherosclerosis 0.000
Acquired dysfibrinogenemia 0.000
pulmonary embolism 0.000
Thrombophilia 0.000
stroke 0.000
coronary thrombosis 0.000
Owren 0.000
afibrinogenemia 0.000
sepsis 0.000
Congenital dysfibrinogenemia 0.000
sepsis 0.000
von Willebrand disease 0.000
myocardial infarction 0.000
pertussis 0.000
HPC4 0.000
Glanzmann 0.000
hemorrhagic diathesis 0.000
platelet disorder 0.000
antiphospholipid syndrome 0.000
PC deficiency 0.000
thrombocytosis 0.000
acute myocardial infarction 0.000
Acute coagulopathy 0.000
leeches 0.000
DIP 0.000
hypoprothrombinemia 0.000
hemophilia B 0.000
retinoblastoma stage 0.000
Heparin-induced thrombosis 0.000
Factor V inhibition 0.000
RP34 0.000
Retinal microembolism 0.000
plaque 0.000
Abdominal sepsis 0.000
lupus 0.000
lupus 0.000
vascular disease 0.000
Adhesion 0.000
coronary artery disease 0.000
DVT 0.000
APC 0.000
systemic lupus erythematosus 0.000
Saddle PE 0.000
Non-rheumatic atrial fibrillation 0.000
ischemia 0.000
brain edema 0.000
PPP 0.000
hereditary factor VII deficiency 0.000
cardiovascular disease 0.000
postperfusion syndrome 0.000
Congenital afibrinogenemia 0.000
Activated protein C resistance 0.000
thrombopathy 0.000
HMERF 0.000
myocardial ischemia 0.000
cerebral thrombosis 0.000
cancer 0.000
Factor XII deficiency 0.000
EGMA 0.000
venous stasis 0.000
Non-ST elevation myocardial infarction (NSTEMI) 0.000
Skin hemorrhage 0.000
Livedo vasculitis 0.000
Heparin-induced thrombocytopenia with thrombosis 0.000
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Symptom
angina 0.000
Easy bruising 0.000
respiratory distress 0.000
Organ failure 0.000
Breast tenderness 0.000
monoplegia 0.000
hypothermia 0.000
spasm 0.000
anesthesia 0.000
retrosternal discomfort 0.000
dacryops 0.000
exertional angina 0.000
collapse 0.000
livedo 0.000
pain 0.000
intestinal bleeding 0.000
chest pain 0.000
disturbed balance 0.000
localized edema 0.000
HSA 0.000
exhaustion 0.000
Anoxia 0.000
Signs and Symptoms 0.000
loin pain 0.000
agitation 0.000
colic 0.000
hemoptysis 0.000
arm weakness 0.000
functional recovery 0.000
bradypnea 0.000
cyanosis 0.000
seizures 0.000
headache 0.000
splenomegaly 0.000
oliguria 0.000
autodigestion 0.000
dyspnea 0.000
discomfort 0.000
paresis 0.000
discomfort 0.000
mastalgia 0.000
bladder pain 0.000
Scratch 0.000
flushing 0.000
abdominal discomfort 0.000
orthopnea 0.000
microbial colonization 0.000
eds 0.000
hepatomegaly 0.000
stomach pain 0.000
hypoproteinemia 0.000
arm pain 0.000
syncopal episodes 0.000
abdominal cramps 0.000
Decreased activity 0.000
swollen joints 0.000
overweight 0.000
thinning 0.000
hyperoxia 0.000
pleuritic chest pain 0.000
Fluctuation 0.000
acidity 0.000
presyncope 0.000
chills 0.000
menopausal symptoms 0.000
tremor 0.000
acute stress 0.000
groin pain 0.000
chest tightness 0.000
nausea 0.000
diarrhea 0.000
rigors 0.000
consciousness disturbance 0.000
ENT 0.000
epigastric pain 0.000
abdominal pain 0.000
general problem 0.000
dysesthesia 0.000
back pain 0.000
starvation 0.000
more...
Drug
Argatroban 0.001
Antithrombin III 0.001
Hirulog 0.001
Bivalirudin 0.001
Ximelagatran 0.001
Fondaparinux 0.001
Batroxobin 0.000
Ancrod 0.000
Fragmin 0.000
Lepirudin 0.000
LMWH 0.000
TAT 0.000
Dalteparin 0.000
Thrombostat 0.000
NovoSeven 0.000
Orgaran 0.000
Vitamin K 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
uPA 0.000
Apixaban 0.000
Desirudin 0.000
Aprotinin 0.000
Abciximab 0.000
Chrysalin 0.000
Protamine sulfate 0.000
PTC 0.000
lysine 0.000
Asn 0.000
Iloprost 0.000
Eptifibatide 0.000
Fragment 0.000
Phosphatidylserine 0.000
Proflavin 0.000
Cyclotheonamide A 0.000
Streptokinase 0.000
Urokinase 0.000
Nafamostat mesilate 0.000
DFP 0.000
Lovenox 0.000
Cardiovasc 0.000
Gabexate mesilate 0.000
Ozagrel sodium 0.000
FeCl3 0.000
Gel 0.000
Warfarin potassium 0.000
Ethyl icosapentate 0.000
Normiflo 0.000
Indomethacin 0.000
PFA 0.000
Dazoxiben 0.000
Brinase 0.000
Napsagatran 0.000
Sodium trimetaphosphate 0.000
Clivarine 0.000
Clopidogrel 0.000
Propylene glycol alginate 0.000
Calciparine 0.000
Aggrenox 0.000
DDAVP 0.000
Lysophosphatidylglycerol 0.000
Cyclandelate 0.000
Vitamin B12 0.000
DDAVP 0.000
Halofenate 0.000
Bromadryl 0.000
Ardeparin 0.000
CGS 13080 0.000
Indolidan 0.000
Monteplase 0.000
AHF 0.000
Surgicel 0.000
ACT 0.000
Dimetapp 0.000
Plavix 0.000
Ethamsylate 0.000
Diastat 0.000
Warfarin sodium 0.000
Aggrastat 0.000
more...
Enzyme
thrombin 1.000
thromboplastin 0.046
plasmin 0.011
APC 0.007
tissue plasminogen activator 0.003
trypsin 0.002
thrombin-activatable fibrinolysis inhibitor 0.001
kallikrein 0.001
ancrod 0.001
urokinase-type plasminogen activator 0.001
chymotrypsin 0.001
clotting enzyme 0.001
elastase 0.001
phospholipase C 0.001
protein kinase C 0.000
neutrophil elastase 0.000
phospholipase A2 0.000
cathepsin G 0.000
RVV-V 0.000
apyrase 0.000
TAT 0.000
transglutaminase 0.000
tissue kallikrein 0.000
cancer procoagulant 0.000
tryptase 0.000
Hageman factor 0.000
heparinase 0.000
myosin light chain kinase 0.000
carboxypeptidase B 0.000
coagulation factor IXa 0.000
coagulation factor XIa 0.000
thromboxane synthase 0.000
mitogen-activated protein kinase 0.000
lipoxygenase 0.000
TGT 0.000
glutathione S-transferase 0.000
okinaxobin II 0.000
C1 esterase 0.000
coagulation factor VIIa 0.000
protein kinase 0.000
adenylate cyclase 0.000
papain 0.000
aequorin 0.000
matriptase 0.000
phosphodiesterase 0.000
CPN 0.000
thermolysin 0.000
matriptase 0.000
nucleoside N-ribosyltransferase 0.000
12-lipoxygenase 0.000
enterokinase 0.000
guanylate cyclase 0.000
subtilisin 0.000
glutathione-dependent formaldehyde-activating enzyme 0.000
peroxidase 0.000
glycoprotease 0.000
collagenase 0.000
lysyl endopeptidase 0.000
atroxase 0.000
deaminase 0.000
chondroitin ABC lyase 0.000
phosphoinositide 3-kinase 0.000
neuropsin 0.000
phosphatidylinositol 3-kinase 0.000
phospholipase D 0.000
PKG 0.000
asparaginase 0.000
neuropsin 0.000
Ins(1,4,5)P3 3-kinase 0.000
lactate dehydrogenase 0.000
chymase 0.000
PAF acetyltransferase 0.000
diaminopropionate ammonia-lyase 0.000
imidazolonepropionase 0.000
proteinase yscD 0.000
neuraminidase 0.000
ERK 0.000
MEK 0.000
NO synthase 0.000
focal adhesion kinase 0.000
more...
Compound
Thrombin 0.085
ADP 0.005
ADP 0.004
ADP 0.004
Fibrin 0.003
Fibrinogen 0.003
Heparin 0.002
Argatroban 0.001
calcium 0.001
prostacyclin 0.001
arginine 0.001
Fibrinopeptide A 0.001
Factor X 0.001
serine 0.001
Plasmin 0.001
FDP 0.000
sulfate 0.000
Gly 0.000
Dermatan sulfate 0.000
prostaglandin E1 0.000
Phe 0.000
SDS 0.000
tyrosine 0.000
PAR 0.000
EDTA 0.000
Warfarin 0.000
EDTA 0.000
Dermatan sulfate 0.000
sodium 0.000
TXA2 0.000
Asp 0.000
PMSF 0.000
lysine 0.000
DIC 0.000
Vitamin K 0.000
cAMP 0.000
Benzamidine 0.000
Thromboxane B2 0.000
cGMP 0.000
acetate 0.000
ATP 0.000
CaCl2 0.000
4-ethylpiperidine 0.000
1-isopropylpiperidine 0.000
Trypsin 0.000
ETH 0.000
TGT 0.000
alanine 0.000
Dec 0.000
ASA 0.000
NH2 0.000
AMP 0.000
DNA 0.000
Polybrene 0.000
nitric oxide 0.000
PMA 0.000
Clin 0.000
Protamine 0.000
threonine 0.000
leucine 0.000
phosphate 0.000
Ticlopidine 0.000
Collagen 0.000
His 0.000
PMA 0.000
PGH2 0.000
Arachidonic acid 0.000
DEAE 0.000
GTP 0.000
Triton X-100 0.000
9-allyl-6-chloro-9H-purine 0.000
20-OH-LTE4 0.000
Frangulin B 0.000
KT-6 0.000
TEG 0.000
Phosphatidylserine 0.000
Ile 0.000
prostaglandin F1 0.000
cysteine 0.000
3,4,9,10-perylenetetracarboxylic acid 0.000
more...