Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.5 (thrombin)
33,306 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein thrombin 33120 fibrinogen 5799 prothrombin 3713 collagen 2650 factor Xa 2515 antithrombin 2399 Sep 2296 ADP 2152 thromboplastin 2148 antithrombin III 2115 tissue factor 1640 protein C 1391 thrombomodulin 1075 thrombin inhibitor 1003 Mol 954 von Willebrand factor 942 glycoprotein 940 thrombin receptor 933 PLA 922 plasminogen 877 serine protease 872 factor VIII 723 ATP 677 SDS 621 P-selectin 609 GPIIb 577 urokinase-type plasminogen activator 558 factor V 535 tissue plasminogen activator 520 bradykinin 493 protein S 475 factor VII 454 VIII 453 albumin 445 plasminogen activator inhibitor 433 plasminogen activator inhibitor-1 431 polypeptide 416 chymotrypsin 415 PAR-1 414 fibronectin 408 heparin cofactor II 393 cytokine 380 kallikrein 356 cyclooxygenase 354 platelet factor 4 339 PAR1 338 tissue factor pathway inhibitor 325 insulin 323 lipopolysaccharide 321 Prothrombin 318 AMP 314 epidermal growth factor 296 phospholipase A2 287 beta-thromboglobulin 277 tumor necrosis factor 275 platelet-derived growth factor 275 glycoprotein IIb 271 vascular endothelium 259 NMR 255 platelet-derived 246 FVIII 244 Rho 241 trypsin inhibitor 239 factor IX 239 GPIb 236 Thrombomodulin 236 Protein C 225 tyrosine kinase 224 heavy chain 216 CD62P 213 factor XI 210 hemoglobin 209 GTP 201 Factor VIII 198 protease-activated receptor-1 198 serum albumin 198 PAR4 187 RhoA 186 IL-6 185 fused 182 more...

Disease cancer 879 stroke 810 disseminated intravascular coagulation 785 thrombocytopenia 689 tumor 650 atherosclerosis 639 SDS 621 myocardial infarction 504 sepsis 483 sepsis 460 deep vein thrombosis 440 coagulopathy 435 diabetes 377 haemophilia 349 hypertension 319 ischemia 296 pulmonary embolism 275 Haemophilia 271 pertussis 263 plaque 263 cardiovascular disease 242 acute myocardial infarction 231 coronary artery disease 226 systemic lupus erythematosus 217 unstable angina 187 PAF 182 lupus 168 myocardial ischemia 154 Thrombus 151 vascular disease 144 Alzheimer's disease 141 lupus 139 cirrhosis 130 tumor growth 120 Glanzmann's thrombasthenia 120 von Willebrand disease 118 melanoma 117 breast cancer 115 leukemia 112 carcinoma 110 APC 107 liver disease 105 SEM 105 antiphospholipid syndrome 103 metastases 97 tumor progression 97 asthma 95 Heparin-induced thrombocytopenia 93 coronary heart disease 92 obesity 92 cold 91 hepatocellular carcinoma 89 renal failure 85 Bernard-Soulier syndrome 85 thrombocytosis 83 dysfibrinogenemia 82 Adhesion 82 HIV 82 type 2 diabetes 82 preeclampsia 81 sickle cell disease 79 multiple myeloma 79 depression 74 heart failure 74 coronary thrombosis 72 neuroblastoma 69 cerebral ischemia 69 rheumatoid arthritis 66 renal disease 66 brain edema 64 NAME 64 hyperlipidemia 64 hypofibrinogenemia 63 pulmonary hypertension 62 hypercholesterolemia 61 Blocking 58 pulmonary edema 56 mole 55 mole 54 anemia 54 more...

Symptom anesthesia 118 pain 114 angina 104 respiratory distress 74 hypothermia 48 collapse 41 seizures 35 spasm 31 headache 29 chest pain 25 exhaustion 19 dyspnea 17 agitation 17 functional recovery 16 diarrhea 16 discomfort 15 discomfort 15 overweight 13 abdominal pain 11 splenomegaly 11 hemoptysis 11 nausea 10 fatigue 10 weakness 9 starvation 9 tremor 9 acidity 9 HSA 9 thinning 8 vomiting 8 colic 8 analgesia 8 paresis 7 flushing 7 cyanosis 7 livedo 6 exertional angina 6 erythema 6 back pain 6 hepatomegaly 6 hyperoxia 5 dizziness 5 distraction 5 intestinal bleeding 5 chills 4 ENT 4 acute stress 4 oliguria 4 lethargy 3 Organ failure 3 epigastric pain 3 monoplegia 3 abdominal discomfort 3 myalgia 3 hepatosplenomegaly 3 Anoxia 3 arthralgia 3 cough 3 shortness of breath 3 menopausal symptoms 2 acute abdomen 2 neck pain 2 hypoproteinemia 2 microbial colonization 2 Welt 2 hypercapnia 2 hunger 2 eds 2 paresthesia 2 numbness 2 anorexia 2 pelvic pain 2 disturbed balance 2 loin pain 2 sleepiness 2 acute pain 2 cachexia 2 Scratch 1 Postoperative pain 1 cerebellar ataxia 1 more...

Drug Cardiovasc 467 lysine 327 CaCl2 149 CaCl2 147 CaCl2 147 Antithrombin III 145 Asn 144 TAT 127 Gel 112 Argatroban 107 uPA 84 Fondaparinux 81 Bivalirudin 72 Vitamin K 71 Indomethacin 69 LMWH 60 Ximelagatran 59 PTC 57 Fragment 55 vitamin E 50 Aprotinin 49 Dalteparin 44 MAP 44 Fragmin 43 ascorbate 41 Hirulog 41 Dermatol 41 Ancrod 38 Histamine 38 NovoSeven 37 ABC 36 FeCl3 36 DFP 33 NADH 32 nitroglycerin 32 Apixaban 30 Nephron 30 Batroxobin 30 Dial 30 Phosphatidylserine 29 ACT 29 Lepirudin 28 Albumin 27 Iloprost 27 PFA 27 Urokinase 27 Abciximab 26 Clopidogrel 26 Streptokinase 26 Ethanol 25 CSF 24 Vitamin B12 23 DNase I 22 Leaf 22 DDAVP 21 IFN-gamma 21 ROS 21 Forskolin 20 DDAVP 20 ETA 19 Monit 18 Thrombostat 18 Orgaran 17 Biopolymers 16 Fraction 16 Nephron 16 Gelatin 15 Protamine sulfate 15 Angiotensin II 15 Gelfoam 15 ROC 14 EPA 13 Eptifibatide 13 Lovastatin 13 caffeine 13 AHF 13 CTA 13 IL-2 13 Methylene blue 13 Bayer 12 more...

Enzyme thrombin 33306 thromboplastin 4505 APC 2009 plasmin 1812 trypsin 1519 tissue plasminogen activator 1062 protein kinase C 901 urokinase-type plasminogen activator 590 phospholipase C 561 mitogen-activated protein kinase 494 kallikrein 491 chymotrypsin 478 elastase 396 phospholipase A2 381 protein kinase 372 glutathione S-transferase 230 neutrophil elastase 206 peroxidase 205 ERK 201 transglutaminase 179 adenylate cyclase 177 phosphodiesterase 150 lipoxygenase 148 cathepsin G 134 focal adhesion kinase 132 TAT 127 lactate dehydrogenase 116 apyrase 115 tryptase 112 ATPase 110 ACS 107 thrombin-activatable fibrinolysis inhibitor 106 collagenase 106 myosin light chain kinase 98 alkaline phosphatase 97 papain 96 superoxide dismutase 95 ancrod 87 MEK 87 guanylate cyclase 81 tissue kallikrein 79 creatine kinase 79 NO synthase 79 neuraminidase 78 catalase 77 phosphatidylinositol 3-kinase 73 luciferase 68 heparinase 68 calcineurin 66 caspase-3 66 alanine aminotransferase 61 reverse transcriptase 59 clotting enzyme 58 subtilisin 56 phosphoinositide 3-kinase 55 NADPH oxidase 54 deaminase 53 lysozyme 52 AMPK 49 Hageman factor 47 NADPH oxidase 47 ACE 47 hyaluronidase 46 pepsin 45 carboxypeptidase B 44 thermolysin 44 aequorin 43 phospholipase D 42 renin 38 beta-glucuronidase 38 thromboxane synthase 38 lipoprotein lipase 37 hexosaminidase 36 acetylcholinesterase 35 asparaginase 35 TGT 35 PKG 34 aspartate aminotransferase 34 MAP 33 cathepsin B 32 more...

Compound calcium 3656 Thrombin 3477 ADP 2729 Dec 2408 ADP 2172 ADP 2153 arginine 1858 Clin 1797 DNA 1396 serine 1351 sodium 1223 sulfate 1148 tyrosine 835 prostacyclin 709 Heparin 680 ATP 678 SDS 656 Phe 656 acetate 648 lysine 617 phosphate 582 Gly 561 Fibrinogen 491 cAMP 477 Fibrin 473 nitric oxide 455 alanine 448 EDTA 423 Asp 419 water 419 oxygen 409 EDTA 393 His 368 Cardiol 361 NH2 350 leucine 342 AMP 323 cysteine 306 threonine 300 hydrogen 281 glucose 281 cGMP 277 prostaglandin E1 252 salt 211 methionine 205 GTP 203 ASA 201 urea 174 PEG 172 Ile 164 TNF 160 ethanol 159 galactose 154 DEAE 152 CaCl2 149 Triton X-100 145 PMA 145 TEM 138 PAR 132 Warfarin 129 PMA 128 Collagen 126 ACS 125 iron 122 Factor X 121 creatinine 120 PEG 118 Plasmin 118 FDP 117 proline 114 potassium 113 5-HT 112 H2O2 111 bromide 111 DIC 109 zinc 108 ACS 107 glycerol 106 Argatroban 104 Mg2+ 104 more...

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