Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.5 (thrombin)
 33,306 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ZA protein 9.9
serum prothrombin conversion accelerator 9.9
integrator complex subunit 4 9.9
PKC-potentiated PP1 inhibitory protein 9.9
CRADD protein 9.9
human factor FVIII 9.9
thrombin 9.9
protease-activated receptor 3 9.5
Thrombin receptor 9.4
PAR4 9.3
protease-activated receptor 1 9.2
thrombin receptor 9.2
heparin cofactor II 9.1
Heparin cofactor II 9.1
PAR-1 9.0
protease-activated receptor-1 9.0
signalosome subunit 3 8.9
FGL2 protein 8.9
Platelet phospholipase A2 8.9
DC33 8.9
Regulator of G-protein signaling 18 8.9
NAT6 8.9
SERPINE2 protein 8.9
F11R protein 8.9
thrombin inhibitor 8.9
PAR-4 8.9
factor Xa 8.9
PAR1 8.9
antithrombin 8.8
Thrombomodulin 8.8
effector cell protease receptor-1 8.8
proteinase inhibitor 8 8.7
PAR3 8.6
CHERP 8.6
Antithrombin 8.6
Fibrinopeptide A 8.5
antithrombin III 8.5
thrombomodulin 8.5
thrombin-activatable fibrinolysis inhibitor 8.5
protease-activated receptor 4 8.5
more...
Disease
Acquired dysfibrinogenemia 9.9
Factor V inhibition 9.9
Retinal microembolism 9.9
retinoblastoma stage 9.9
Heparin-induced thrombosis 9.9
RP34 9.9
Saddle PE 8.9
Non-rheumatic atrial fibrillation 8.9
Congenital dysfibrinogenemia 8.7
Acute coagulopathy 8.7
HPC4 8.6
HMERF 8.3
Scott syndrome 8.3
dysfibrinogenemia 8.3
Livedo vasculitis 7.9
hereditary factor VII deficiency 7.9
Non-ST elevation myocardial infarction (NSTEMI) 7.9
Skin hemorrhage 7.9
Owren 7.6
Erythrocytopenia 7.6
Generalized atherosclerosis 7.6
Abdominal sepsis 7.5
postperfusion syndrome 7.5
EGMA 7.4
hyperheparinemia 7.3
gray syndrome 7.3
WFS2 7.3
Heparin-induced thrombocytopenia with thrombosis 7.3
Cavernous lymphangioma 7.3
Heparin-induced thrombocytopenia 7.2
von Willebrand disease type 2B 7.1
Carotid artery thrombosis 7.1
von Willebrand disease type 2B 7.1
Caffeine withdrawal 7.1
Glanzmann 7.1
Glanzmann's thrombasthenia 7.0
afibrinogenemia 7.0
Transient amnesia 6.9
Hepatosplenic schistosomiasis 6.9
hypofibrinogenemia 6.8
more...
Symptom
Easy bruising 6.4
Breast tenderness 5.8
Organ failure 5.5
retrosternal discomfort 4.8
monoplegia 4.7
dacryops 4.7
localized edema 3.2
disturbed balance 3.1
exertional angina 2.9
Signs and Symptoms 2.8
livedo 2.7
intestinal bleeding 2.6
loin pain 2.6
Anoxia 2.4
arm weakness 2.4
bradypnea 2.3
angina 2.2
spasm 2.0
respiratory distress 1.8
autodigestion 1.6
HSA 1.5
hypothermia 1.4
mastalgia 1.3
bladder pain 1.3
Scratch 1.3
colic 1.3
orthopnea 1.1
oliguria 1.1
stomach pain 0.9
syncopal episodes 0.9
arm pain 0.9
microbial colonization 0.9
abdominal cramps 0.8
eds 0.8
Decreased activity 0.8
swollen joints 0.8
cyanosis 0.8
hemoptysis 0.8
hypoproteinemia 0.8
abdominal discomfort 0.7
more...
Drug
Cyclotheonamide A 9.9
Hirulog 9.5
Desirudin 8.9
Ozagrel sodium 8.9
Batroxobin 8.8
Argatroban 8.8
Chrysalin 8.7
Ximelagatran 8.7
Ancrod 8.5
Bivalirudin 8.4
Lepirudin 8.3
Normiflo 8.3
Warfarin potassium 8.3
Ethyl icosapentate 8.3
Proflavin 8.2
Antithrombin III 8.0
Thrombostat 8.0
Fondaparinux 7.9
Sodium trimetaphosphate 7.9
Napsagatran 7.9
Clivarine 7.9
Orgaran 7.8
Fragmin 7.8
Brinase 7.4
Propylene glycol alginate 7.3
Lysophosphatidylglycerol 7.3
Monteplase 7.1
Indolidan 7.1
Ardeparin 7.1
Bromadryl 7.1
Aggrenox 7.0
Nafamostat mesilate 6.9
Dimetapp 6.9
Protamine sulfate 6.9
Dalteparin 6.9
NovoSeven 6.8
Calciparine 6.8
LMWH 6.7
Halofenate 6.7
Gabexate mesilate 6.7
more...
Enzyme
thrombin 9.9
okinaxobin II 9.9
RVV-V 9.7
nucleoside N-ribosyltransferase 8.9
thrombin-activatable fibrinolysis inhibitor 8.7
coagulation factor IXa 8.5
ancrod 8.5
thromboplastin 8.3
clotting enzyme 8.3
coagulation factor XIa 8.0
glutathione-dependent formaldehyde-activating enzyme 7.9
cancer procoagulant 7.7
plasmin 7.6
atroxase 7.6
C1 esterase 7.3
diaminopropionate ammonia-lyase 7.1
imidazolonepropionase 7.1
proteinase yscD 7.1
coagulation factor VIIa 7.0
endopeptidase I 6.9
APC 6.9
spermosin 6.7
tissue plasminogen activator 6.5
Hageman factor 6.5
kallikrein 6.3
duodenase 6.3
apyrase 6.2
cathepsin G 6.2
carboxypeptidase B 6.1
fibrolase 6.1
TGT 6.0
Ins(1,4,5)P3 3-kinase 6.0
thromboxane synthase 6.0
vitamin K epoxidase 6.0
atrolysin C 6.0
PAF acetyltransferase 6.0
glycoprotease 5.9
tissue kallikrein 5.9
neurosin 5.9
neuropsin 5.8
more...
Compound
1-isopropylpiperidine 9.9
9-allyl-6-chloro-9H-purine 9.9
KT-6 9.9
20-OH-LTE4 9.9
4-ethylpiperidine 9.9
Frangulin B 9.9
Thrombin 9.6
Fibrinopeptide A 8.9
Tripteroside 8.9
4-(chloromethyl)benzoic acid 8.9
Isotetrandrine 8.9
Argatroban 8.8
2,5,8,11,14-pentaoxapentadecane 8.3
Diisoeugenol 8.3
C6H6N4 8.3
C10H8O2 8.3
TIPPS 8.3
13-cis-Retinal 8.3
Trihexosylceramide 7.9
nonacosanoic acid 7.9
11(R)-HETE 7.9
2,2-diphenyltetrahydrofuran 7.9
phenylmethanesulfonic acid 7.9
Denudatin B 7.9
Scolymoside 7.9
NSC 176319 7.9
Factor X 7.9
Benzamidine 7.7
Fibrin 7.7
Adchnon 7.6
C6H7NO 7.6
4-Chlorobiphenyl 7.6
N-Acetylimidazole 7.6
3-morpholinone 7.6
PGF3alpha 7.6
2-Hydroxy-5-nitrobenzyl bromide 7.6
Dithiodipropionic acid 7.6
Fibrinogen 7.5
3-aminophenylalanine 7.4
3,4,9,10-perylenetetracarboxylic acid 7.4
more...