Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.5 (thrombin)
 33,306 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thrombin 33120
fibrinogen 5799
prothrombin 3713
collagen 2650
factor Xa 2515
antithrombin 2399
Sep 2296
ADP 2152
thromboplastin 2148
antithrombin III 2115
tissue factor 1640
protein C 1391
thrombomodulin 1075
thrombin inhibitor 1003
Mol 954
von Willebrand factor 942
glycoprotein 940
thrombin receptor 933
PLA 922
plasminogen 877
more...
Disease
cancer 879
stroke 810
disseminated intravascular coagulation 785
thrombocytopenia 689
tumor 650
atherosclerosis 639
SDS 621
myocardial infarction 504
sepsis 483
sepsis 460
deep vein thrombosis 440
coagulopathy 435
diabetes 377
haemophilia 349
hypertension 319
ischemia 296
pulmonary embolism 275
Haemophilia 271
plaque 263
pertussis 263
more...
Symptom
anesthesia 118
pain 114
angina 104
respiratory distress 74
hypothermia 48
collapse 41
seizures 35
spasm 31
headache 29
chest pain 25
exhaustion 19
dyspnea 17
agitation 17
diarrhea 16
functional recovery 16
discomfort 15
discomfort 15
overweight 13
hemoptysis 11
splenomegaly 11
more...
Drug
Cardiovasc 467
lysine 327
CaCl2 149
CaCl2 147
CaCl2 147
Antithrombin III 145
Asn 144
TAT 127
Gel 112
Argatroban 107
uPA 84
Fondaparinux 81
Bivalirudin 72
Vitamin K 71
Indomethacin 69
LMWH 60
Ximelagatran 59
PTC 57
Fragment 55
vitamin E 50
more...
Enzyme
thrombin 33306
thromboplastin 4505
APC 2009
plasmin 1812
trypsin 1519
tissue plasminogen activator 1062
protein kinase C 901
urokinase-type plasminogen activator 590
phospholipase C 561
mitogen-activated protein kinase 494
kallikrein 491
chymotrypsin 478
elastase 396
phospholipase A2 381
protein kinase 372
glutathione S-transferase 230
neutrophil elastase 206
peroxidase 205
ERK 201
transglutaminase 179
more...
Compound
calcium 3656
Thrombin 3477
ADP 2729
Dec 2408
ADP 2172
ADP 2153
arginine 1858
Clin 1797
DNA 1396
serine 1351
sodium 1223
sulfate 1148
tyrosine 835
prostacyclin 709
Heparin 680
ATP 678
SDS 656
Phe 656
acetate 648
lysine 617
more...