Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.4 (trypsin)
 42,187 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

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Human Gene/Protein
CTRL protein 9.6
ITIH4 protein 9.6
zinc finger protein 432 9.6
tryptase I 9.6
ATHL1 9.6
alpha subunit of GsGTP binding protein 9.6
Tryptase I 9.6
Protease, serine, 3 9.6
Tracheobronchial mucin 9.6
protein DDX26B 9.6
OVCH1 9.6
mMCP-7-like I 9.6
cAMP-dependent protein kinase type I-beta regulatory subunit 9.6
C16orf89 9.6
testis serine protease 5 9.6
TYSND1 9.6
MiIX 9.6
Ig kappa chain V-III region SIE 9.6
kallikrein-related peptidase 15 9.6
Prostinogen 9.6
SPINK2 protein 9.6
skin tryptase 9.4
trypsin I 9.3
tryptase beta I 9.3
beta-tryptase 9.2
Trypsin-2 9.1
elastase 2A 9.1
tryptase epsilon 9.1
mesotrypsinogen 8.9
trypsin 1 8.8
Mast cell tryptase 8.8
carboxypeptidase A3 8.8
proteinase inhibitor 8 8.8
marapsin 8.8
mesotrypsin 8.7
Trypsin 8.7
mast cell tryptase 8.7
TPSAB1 8.6
trypsinogen 4 8.6
Orosomucoid 2 8.6
60S ribosomal protein L7 8.6
DESC1 8.6
Serase-1B 8.6
Trypsinogen 4 8.6
EGF-like module-containing mucin-like hormone receptor-like 2 8.6
TJP4 8.6
phospholipase C beta-2 8.6
KLK15 protein 8.6
SPINK9 8.6
aminopeptidase O 8.6
chondroitinsulfatase 8.6
Yes-associated protein 2 8.6
zinc finger protein 222 8.6
TRY1 8.6
GARNL3 8.6
OR1D4 8.6
progestin and adipoQ receptor family member III 8.6
anionic trypsinogen 8.6
1,4-beta-poly-N-acetylglucosaminidase 8.6
vitelline membrane outer layer 1 8.6
HLF2 8.6
HLA-DRB1 protein 8.6
chymotrypsin 8.5
enteropeptidase 8.4
serine protease 1 8.4
trypsinogen 8.3
proteinase-activated receptor-2 8.3
pancreatopeptidase E 8.2
TMPRSS11A 8.2
Kallikrein 5 8.2
SERPINB12 8.2
centerin 8.2
chymase 8.2
Protease-activated receptor 2 8.2
cationic trypsinogen 8.1
chymotrypsin-like 8.1
trypsin inhibitor 8.0
Chymotrypsin 8.0
KKI 8.0
ADA2B 8.0
more...
Disease
NEDE 9.6
Peripheral retinitis 9.6
Acinar cell cystadenocarcinoma 9.6
embryo hypoxia 8.6
Benign mesenchymal neoplasms 8.6
CAAR 8.0
familial hypothyroidism 8.0
Hemorrhagic pancreatitis 7.7
Peripancreatic necrosis 7.6
Psoriatic plaque 7.4
Pancreatic duct obstruction 7.4
Hereditary chronic pancreatitis 7.4
Alcoholic liver damage 7.2
RP30 7.2
Idiopathic anaphylaxis 7.1
Carcinoid crisis 7.0
noninfectious hepatitis 7.0
Struck 6.6
SPD1 6.6
Cockroach allergy 6.6
Baker's asthma 6.6
mast cell leukemia 6.5
Senear-Usher syndrome 6.5
Systemic mastocytosis 6.5
Seropositive rheumatoid arthritis 6.4
Fibrosing colonopathy 6.4
congestive atelectasis 6.4
VCPDM 6.4
Edematous pancreatitis 6.3
Cutaneous cysts 6.2
BDB 6.2
Mastocytosis 6.1
Eosinophilic disorders 6.1
mastocytosis 6.0
pig-bel 6.0
Irreversible shock 6.0
streptoccocal 6.0
Cutaneous mastocytosis 5.9
urticaria pigmentosa 5.9
Other dermatoses 5.9
Teschen disease 5.9
Diffuse cutaneous mastocytosis 5.9
pancreatic insufficiency 5.8
Tripe palms 5.8
RP19 5.8
Bile duct proliferation 5.8
AD7 5.7
WNS 5.6
Neuropathogenesis 5.6
Irvine-Gass syndrome 5.5
histiocytic leukemia 5.4
dental deposit 5.4
Fletcher trait 5.4
Netherton syndrome 5.3
steatorrhea 5.3
Retinol deficiency 5.3
AA1 5.3
Neonatal calf diarrhea 5.3
adult medulloblastoma 5.3
Oroya fever 5.2
EA4 5.2
Elastolysis 5.2
SM-AHNMD 5.2
mastocytoma 5.2
TD2 5.1
acute pancreatitis 5.1
Porencephaly 5.1
Takahara 5.1
gluten sensitivity 5.1
metaphyseal dysostosis 5.0
Mastocytoma 5.0
Flavivirus infection 5.0
Hyperamylasemia 5.0
Acute necrotizing pancreatitis 5.0
fogo selvagem 5.0
MF4 5.0
Pancreatic duct 4.9
SDS 4.9
ANM 4.9
Pruritic urticarial papules and plaques of pregnancy 4.9
more...
Symptom
Mucoid sputum 9.6
autodigestion 7.1
Local swelling 5.9
Darier's sign 5.5
Bladder distention 5.2
dyslalia 5.0
Spots 5.0
PUO 4.8
Nasal symptoms 4.4
No toxic effect 4.2
rundown 3.4
prominent nose 3.2
scaly skin 3.1
Blanching 2.8
HSA 2.7
generalized erythema 2.7
hypoproteinemia 2.6
sneezing 2.6
generalized rash 2.4
dry skin 2.4
halitosis 2.3
acid regurgitation 2.2
Flare 2.1
flushing 2.1
prostration 2.0
eds 1.8
disturbed balance 1.7
ACHE 1.7
postnasal drip 1.5
Decreased activity 1.5
agitation 1.2
No adverse effect 1.2
rhinorrhea 1.2
diarrhea 1.2
nasal congestion 1.0
skin damage 1.0
bladder pain 1.0
starvation 0.9
bloating 0.9
nasal discharge 0.7
Halo 0.7
DNA marker 0.7
bitter taste 0.7
collapse 0.6
stomach pain 0.6
microbial colonization 0.5
wheezing 0.5
Hudson 0.5
Anoxia 0.5
urinary frequency 0.4
adenitis 0.4
Gastrointestinal symptoms 0.4
stridor 0.4
Fluctuation 0.3
presyncope 0.3
acidity 0.3
colic 0.2
Mills 0.2
Wind 0.2
abdominal pain 0.2
leg edema 0.2
twitching 0.1
right upper quadrant pain 0.1
epigastric pain 0.1
erythema 0.1
CSR 0.1
heartburn 0.1
tremor 0.1
hepatosplenomegaly 0.0
anosmia -0.0
cancer pain -0.0
bone pain -0.0
cachexia -0.1
lethargy -0.1
vomiting -0.1
rigors -0.1
masculinization -0.2
general problem -0.2
hyperoxia -0.2
dry eye -0.2
more...
Drug
Cyclotheonamide A 9.6
Elaszym 8.6
Emadine 8.0
Epsilon-Aminocaproic acid 8.0
Brinase 7.7
3,4-Dichloroisocoumarin 7.7
Astelin 7.6
Tarazepide 7.6
Insulin precursor 7.6
Pronase 7.2
Patanol 7.1
Methylprednisolone succinate 7.0
Pancreatin 6.9
Loxonin 6.8
Butylamine 6.8
Gabexate mesilate 6.7
Aprotinin 6.6
Berberine sulfate 6.6
Chitotriose 6.6
Phenylphosphate 6.4
Papain 6.3
Protein hydrolysate 6.3
Proflavin 6.2
Hadacidin 6.2
Emedastine difumarate 6.2
Lexipafant 6.2
Prolastin 6.2
1,4-Dithiothreitol 6.1
Kallidinogenase 6.1
Oxyphenbutazone 6.0
Bromelain 6.0
Iletin II 6.0
Banminth 6.0
Loxiglumide 6.0
Oxyphenbutazone 5.9
Fennel 5.8
Elcatonin 5.8
Trazodon 5.8
Camostat mesilate 5.8
Formycin 5.8
Pancrease 5.8
DFP 5.7
Nafamostat mesilate 5.6
1-Deoxymannojirimycin 5.6
Sulfamide 5.5
Argininosuccinate 5.5
Hemolink 5.5
Dexamethasone acetate 5.5
Olopatadine hydrochloride 5.4
Hirulog 5.4
Terbutaline sulfate 5.3
Gelfilm 5.2
Pepstatin 5.2
Plasmanate 5.2
Cadralazine 5.1
Ulinastatin 5.0
Febantel 5.0
Cardizem CD 4.9
Mycostatin 4.9
Hemopure 4.9
Ancrod 4.9
Carbopol 934P 4.9
Secretin 4.9
Tora 4.8
Minocin 4.8
Cibacron Blue 4.7
Lysostaphin 4.7
Tenecteplase 4.7
Isosulfan blue 4.7
AMC 4.6
Bicine 4.6
Asn 4.5
Gel 4.5
Prulifloxacin 4.5
Dodecyl Sulfate 4.4
Hypromellose 4.4
Pentamidine isethionate 4.4
Pegaspargase 4.4
PE2 4.3
Lactase 4.2
more...
Enzyme
brachyurin 9.6
snapalysin 9.6
trypsin 9.6
pyrrolooxygenase 9.6
spermosin 9.4
tryptase 9.4
Leu-proteinase 9.0
chymotrypsin 8.6
hemorrhagic proteinase IV 8.6
LDL receptor kinase 8.6
nucleoside N-ribosyltransferase 8.6
gamma-renin 8.6
chondroitinsulfatase 8.6
Scytalidium lignicolum acid proteinase 8.6
duodenase 8.5
chymotrypsin C 8.4
stratum corneum tryptic enzyme 8.4
kallikrein 14 8.3
peptidyl-Lys metalloendopeptidase 8.2
chymase 8.2
pancreatic elastase 2 8.2
carboxypeptidase B 8.0
kallikrein 12 8.0
quercetin 3-O-methyltransferase 8.0
sinapine esterase 8.0
neprilysin-2 8.0
hippostasin 8.0
yeast ribonuclease 8.0
clostripain 7.9
endoproteinase Asp-N 7.9
endoproteinase Glu-C 7.8
coagulation factor XIa 7.8
ficin 7.8
complement subcomponent C1r 7.8
enterokinase 7.6
phosphoamidase 7.6
mast cell protease 5 7.6
EC 2.4.1.122 7.6
flavastacin 7.6
thermolysin 7.5
protein methylase I 7.4
prostase 7.4
carboxypeptidase A 7.2
beta-lytic protease 7.2
meprin B 7.2
hypodermin C 7.2
undecaprenyl pyrophosphate synthetase 7.2
H2-proteinase 7.2
acrosin 7.2
EC 1.1.1.101 7.2
kallikrein 13 7.2
CMP-sialic acid hydrolase 7.2
UDP-glucose:dolichol phosphate glucosyltransferase 7.2
lysyl endopeptidase 7.2
cucumisin 7.1
actinase E 7.1
tissue kallikrein 7.1
protein methylase I 7.1
prostasin 7.1
pepsin 7.0
Streptomyces griseus protease B 7.0
phytanoyl-CoA ligase 7.0
papain 7.0
subtilisin 7.0
alpha-lytic protease 6.9
stratum corneum chymotryptic enzyme 6.9
oligopeptidase B 6.9
elastase 6.9
KLK7 6.9
RVV-V 6.9
bromelain 6.9
cathepsin G 6.8
dihydrolipoyl transacylase 6.8
bacillolysin 6.8
CBPP 6.8
NMN glycohydrolase 6.8
hepsin 6.8
diaminopropionate ammonia-lyase 6.8
proteinase yscD 6.8
hepsin 6.8
more...
Compound
C24H40O4 9.6
C24H40O4 9.6
6-aminotryptophan 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
C24H40O4 9.6
Torquatone 9.6
C24H40O4 9.6
4-Amino-3-nitrobenzoic acid 9.6
Orange R 9.6
Trypsin 8.7
3-phenyl-1H-indazole 8.6
C7H6O4 8.6
Luvatren 8.6
C7H6O4 8.6
C7H6O4 8.6
1,2-dibromo-1,2-dichloroethane 8.6
TNY 8.6
C7H6O4 8.6
C24H40O4 8.6
Salcomine 8.6
C7H6O4 8.6
C7H6O4 8.6
C24H40O4 8.6
Benzyloxycarbonyl-L-alanine 8.6
C7H6O4 8.6
Brunfelsamidine 8.6
C6H6N4 8.0
Aranciamycin 8.0
Allochenodeoxycholic acid 8.0
Triricinolein 8.0
C9H10N4O 8.0
Coumalic acid 8.0
4-ethylpiperidine 8.0
C10H8O2 8.0
3-bromopropanoic acid 8.0
TPCK 8.0
Aquacobalamin 7.6
Isoursodeoxycholic acid 7.6
phenylmethanesulfonic acid 7.6
Substance B 7.6
3-sulfobenzoic acid 7.6
5-bromotryptophan 7.6
3-sulfobenzoic acid 7.6
3-sulfobenzoic acid 7.6
Z-Gly-Pro 7.5
GDMA 7.4
Benzamidine 7.4
3,4,5-trihydroxybenzaldehyde 7.2
Pulchellin 7.2
4-(4-hydroxyphenyl)butanoic acid 7.2
C3H4O2 7.2
S-Methylglutathione 7.2
Pseudoisocyanine 7.2
N-Acetylimidazole 7.2
isodeoxycholic acid 7.2
Z-Gly 7.1
Versene 7.1
diphenyl phosphonate 7.0
AcPyAD 7.0
C3H4O2 7.0
Azocoll 6.9
Azocasein 6.8
Hexahydrophthalic anhydride 6.8
1,2-cyclohexanedione 6.8
CEPC 6.8
Girard P reagent 6.8
DHS-I 6.8
Guazatine 6.8
Bilirubin diglucuronide 6.8
Ac-Tyr-OEt 6.8
N-Acetylserine 6.8
4-methylbenzenesulfonohydrazide 6.8
benzenecarboximidamide 6.8
more...