Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.4 (
trypsin
)
42,187
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
chymotrypsin
4896
Sep
2983
Mol
2164
SDS
2011
polypeptide
1814
trypsin inhibitor
1781
Trypsin
1776
thrombin
1535
mast cell
1226
amylase
1207
glycoprotein
1179
ATP
1145
collagenase
1118
serine protease
1100
collagen
1017
lipase
1003
insulin
887
neuraminidase
858
serum albumin
733
ATPase
681
casein
637
chymotrypsin-like
619
protease inhibitor
605
TOF
597
kallikrein
590
albumin
589
lectin
561
chymase
550
trypsinogen
506
gut
480
lysozyme
473
membrane-bound
453
fibronectin
441
IgE
440
proteasome
409
Gen
385
cholecystokinin
375
membrane protein
375
microsomal
373
ADP
369
endoplasmic reticulum
368
alkaline phosphatase
364
Met
359
bradykinin
350
ESI
346
peptidase
344
fibrinogen
331
cytokine
329
urokinase-type plasminogen activator
323
esterase
322
NMR
306
AMP
299
renin
297
hemoglobin
294
factor Xa
285
proteoglycan
280
calmodulin
279
GTP
278
hyaluronidase
274
plasminogen
270
alpha-amylase
268
secretin
261
Pseudomonas
260
serine protease inhibitor
260
peroxidase
260
lipopolysaccharide
251
histone
250
cytochrome c
249
threonine
248
PLA
246
cathepsin G
244
glucosamine
241
mast cell tryptase
240
heavy chain
239
fused
232
Chymotrypsin
232
neutrophil elastase
230
dimeric
220
myosin
220
epidermal growth factor
219
more...
Disease
SDS
2018
cancer
1195
tumor
1177
pancreatitis
559
acute pancreatitis
493
influenza
335
carcinoma
326
asthma
319
plaque
287
diabetes
280
cold
254
cystic fibrosis
249
chronic pancreatitis
244
leukemia
217
anaphylaxis
205
hepatocellular carcinoma
203
breast cancer
193
adenocarcinoma
191
mastocytosis
191
melanoma
177
Alzheimer's disease
173
HIV
160
uterus
150
multiple myeloma
150
Pancreas
150
cholera
144
Pancreas
144
hypertension
139
mole
131
virus infection
131
mole
125
rheumatoid arthritis
117
SEM
114
pancreatic insufficiency
114
pancreatic cancer
114
lymphoma
110
MCF
108
GSH
108
metastases
104
neuroblastoma
99
pertussis
93
infectious diseases
93
malaria
93
atherosclerosis
93
Mycoplasma
92
arthritis
87
celiac disease
85
allergic rhinitis
85
immunodeficiency
84
mastocytoma
83
carcinogenesis
81
emphysema
77
prostate cancer
77
periodontitis
77
atopic dermatitis
75
ischemia
75
sarcoma
75
tumor growth
75
Mycobacterium
75
tumor progression
74
squamous cell carcinoma
71
pruritus
69
osteoarthritis
68
herpes simplex
66
vaccinia
65
steatorrhea
65
depression
65
glioma
62
pneumonia
62
systemic lupus erythematosus
60
Adhesion
60
avian influenza
59
stomatitis
58
Klebsiella
58
worms
57
cirrhosis
57
sepsis
56
hepatitis
56
gastroenteritis
55
psoriasis
53
more...
Symptom
diarrhea
175
pain
130
anesthesia
80
starvation
60
collapse
58
autodigestion
56
abdominal pain
47
vomiting
39
agitation
38
flushing
36
tremor
26
HSA
26
acidity
24
seizures
19
erythema
19
Spots
19
respiratory distress
17
sneezing
15
nausea
15
headache
14
exhaustion
13
cough
12
Welt
12
fatigue
11
weakness
11
dyspnea
11
stigma
9
wheezing
9
syncope
9
discomfort
9
discomfort
9
hypoproteinemia
9
analgesia
9
angina
8
regurgitation
8
thinning
7
cachexia
7
dry skin
7
rundown
7
Ill
7
lethargy
7
anorexia
7
functional recovery
7
rhinorrhea
7
hypothermia
6
spasm
6
splenomegaly
6
hepatosplenomegaly
6
hyperoxia
6
colic
5
chest pain
5
overweight
5
arthralgia
5
eds
5
epigastric pain
5
halitosis
4
skin damage
4
Wind
4
stridor
4
bone pain
4
cancer pain
4
back pain
4
bloating
4
constipation
4
heartburn
3
shortness of breath
3
chills
3
hemoptysis
3
nausea and vomiting
3
paresis
3
Darier's sign
3
bitter taste
3
polyuria
3
Nasal symptoms
3
twitching
3
sleepiness
3
dry eye
3
low back pain
3
hepatomegaly
3
nasal discharge
3
more...
Drug
lysine
1409
Gel
442
Asn
357
Dermatol
327
Pronase
256
NADH
137
ABC
125
Aprotinin
116
CaCl2
112
CaCl2
112
CaCl2
112
lactose
86
ascorbate
81
DNase I
76
CSF
73
IL-2
69
Histamine
67
IFN-gamma
66
DFP
65
Leaf
65
Albumin
62
Papain
59
FAD
57
Asthma
54
L-tyrosine
54
Fragment
52
Fraction
48
NAG
45
MAP
44
pyridoxal phosphate
41
AMC
39
uPA
35
ROS
34
balanced salt solution
34
Biopolymers
32
Gelatin
32
Secretin
29
caffeine
26
Alanine
25
PTH
25
ampicillin
23
Acacia
23
Cardiovasc
22
Nephron
22
CAM
21
Indomethacin
21
Ethanol
20
MRC
20
citric acid
20
Glucagon
20
Ringer's solution
18
Capsicum
18
Cibacron Blue
17
vitamin E
17
CTX
17
Fluorescein
17
Glutathione
16
Paraffin
16
Allergen
15
PTC
15
Bifidobacterium
15
Bromelain
15
Mutagen
15
Hypaque
14
TAT
14
Atropine
14
Fluorescein
14
Angiotensin II
13
Monit
13
Hypaque
13
TiO2
12
CCL
12
Hyaluronidase
11
Hyaluronidase
11
NH3
11
Gabexate mesilate
10
ZnCl2
10
PCP
10
Spectrum
10
Nephron
10
more...
Enzyme
trypsin
42187
chymotrypsin
5478
tryptase
2412
thrombin
1519
pepsin
1491
elastase
1418
collagenase
1166
plasmin
1106
papain
1088
lipase
1016
neuraminidase
908
kallikrein
794
ATPase
734
subtilisin
720
proteinase K
547
chymase
529
proteasome
503
lysozyme
477
RNase
473
thermolysin
463
peroxidase
460
protein kinase
446
RNase
424
neutrophil elastase
374
DNase
370
thromboplastin
366
alkaline phosphatase
364
hyaluronidase
362
urokinase-type plasminogen activator
337
renin
297
phospholipase A2
296
alpha-amylase
281
phospholipase C
277
hyaluronidase
274
cathepsin G
272
tissue kallikrein
226
protein kinase C
226
ribonuclease
220
ribonuclease
219
catalase
214
CD10
209
carboxypeptidase B
206
carboxypeptidase A
197
cathepsin B
194
ERK
186
superoxide dismutase
185
tissue plasminogen activator
184
enterokinase
175
mitogen-activated protein kinase
163
bromelain
157
adenylate cyclase
156
acetylcholinesterase
137
acrosin
136
cathepsin D
136
ACE
136
phosphodiesterase
132
beta-galactosidase
131
glutathione S-transferase
130
endoproteinase Glu-C
124
chondroitinase
122
lactate dehydrogenase
122
chondroitinase
121
APC
118
deaminase
115
alpha-glucosidase
114
leucine aminopeptidase
113
acid phosphatase
113
AMPK
111
deoxyribonuclease
104
deoxyribonuclease
104
ficin
100
PNGase F
99
lysyl endopeptidase
96
reverse transcriptase
95
transglutaminase
94
RNA polymerase
93
ATP synthase
92
calcineurin
92
carboxypeptidase Y
88
invertase
85
more...
Compound
serine
3049
Dec
2973
sodium
2822
arginine
2808
lysine
2534
sulfate
2154
SDS
2149
calcium
2028
DNA
2012
Trypsin
1776
water
1368
Clin
1363
cysteine
1222
ATP
1146
alanine
1071
leucine
1032
Phe
980
phosphate
956
tyrosine
934
methionine
919
EDTA
913
EDTA
913
His
882
Gly
846
Asp
840
ammonium
787
glucose
781
salt
766
NH2
764
urea
749
DEAE
720
bromide
719
galactose
680
threonine
670
TOF
597
hydrogen
556
Ile
539
acetate
528
oxygen
494
Triton X-100
494
Mg2+
428
tryptophan
397
zinc
387
tryptophan
385
ADP
383
tryptophan
375
tryptophan
375
ADP
369
ADP
369
ethanol
356
HCl
338
proline
330
AMP
325
GTP
314
iron
313
cAMP
311
nitrogen
306
PEG
295
guanidine
272
methanol
265
acrylamide
251
potassium
240
copper
230
acetic acid
226
acetone
216
glutamic acid
207
PEG
198
Tris
195
asparagine
194
TCA
194
aspartic acid
194
GlcNAc
192
manganese
191
aspartic acid
191
silver
190
aspartic acid
189
aspartic acid
188
Serine
181
glutamine
177
glycerol
174
more...