Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.4 (trypsin)
42,187 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chymotrypsin 4896
Sep 2983
Mol 2164
SDS 2011
polypeptide 1814
trypsin inhibitor 1781
Trypsin 1776
thrombin 1535
mast cell 1226
amylase 1207
glycoprotein 1179
ATP 1145
collagenase 1118
serine protease 1100
collagen 1017
lipase 1003
insulin 887
neuraminidase 858
serum albumin 733
ATPase 681
casein 637
chymotrypsin-like 619
protease inhibitor 605
TOF 597
kallikrein 590
albumin 589
lectin 561
chymase 550
trypsinogen 506
gut 480
lysozyme 473
membrane-bound 453
fibronectin 441
IgE 440
proteasome 409
Gen 385
cholecystokinin 375
membrane protein 375
microsomal 373
ADP 369
endoplasmic reticulum 368
alkaline phosphatase 364
Met 359
bradykinin 350
ESI 346
peptidase 344
fibrinogen 331
cytokine 329
urokinase-type plasminogen activator 323
esterase 322
NMR 306
AMP 299
renin 297
hemoglobin 294
factor Xa 285
proteoglycan 280
calmodulin 279
GTP 278
hyaluronidase 274
plasminogen 270
alpha-amylase 268
secretin 261
Pseudomonas 260
serine protease inhibitor 260
peroxidase 260
lipopolysaccharide 251
histone 250
cytochrome c 249
threonine 248
PLA 246
cathepsin G 244
glucosamine 241
mast cell tryptase 240
heavy chain 239
fused 232
Chymotrypsin 232
neutrophil elastase 230
dimeric 220
myosin 220
epidermal growth factor 219
more...
Disease
SDS 2018
cancer 1195
tumor 1177
pancreatitis 559
acute pancreatitis 493
influenza 335
carcinoma 326
asthma 319
plaque 287
diabetes 280
cold 254
cystic fibrosis 249
chronic pancreatitis 244
leukemia 217
anaphylaxis 205
hepatocellular carcinoma 203
breast cancer 193
adenocarcinoma 191
mastocytosis 191
melanoma 177
Alzheimer's disease 173
HIV 160
uterus 150
multiple myeloma 150
Pancreas 150
cholera 144
Pancreas 144
hypertension 139
mole 131
virus infection 131
mole 125
rheumatoid arthritis 117
SEM 114
pancreatic insufficiency 114
pancreatic cancer 114
lymphoma 110
MCF 108
GSH 108
metastases 104
neuroblastoma 99
pertussis 93
infectious diseases 93
malaria 93
atherosclerosis 93
Mycoplasma 92
arthritis 87
celiac disease 85
allergic rhinitis 85
immunodeficiency 84
mastocytoma 83
carcinogenesis 81
emphysema 77
prostate cancer 77
periodontitis 77
atopic dermatitis 75
ischemia 75
sarcoma 75
tumor growth 75
Mycobacterium 75
tumor progression 74
squamous cell carcinoma 71
pruritus 69
osteoarthritis 68
herpes simplex 66
vaccinia 65
steatorrhea 65
depression 65
glioma 62
pneumonia 62
systemic lupus erythematosus 60
Adhesion 60
avian influenza 59
stomatitis 58
Klebsiella 58
worms 57
cirrhosis 57
sepsis 56
hepatitis 56
gastroenteritis 55
psoriasis 53
more...
Symptom
diarrhea 175
pain 130
anesthesia 80
starvation 60
collapse 58
autodigestion 56
abdominal pain 47
vomiting 39
agitation 38
flushing 36
tremor 26
HSA 26
acidity 24
seizures 19
erythema 19
Spots 19
respiratory distress 17
sneezing 15
nausea 15
headache 14
exhaustion 13
cough 12
Welt 12
fatigue 11
weakness 11
dyspnea 11
stigma 9
wheezing 9
syncope 9
discomfort 9
discomfort 9
hypoproteinemia 9
analgesia 9
angina 8
regurgitation 8
thinning 7
cachexia 7
dry skin 7
rundown 7
Ill 7
lethargy 7
anorexia 7
functional recovery 7
rhinorrhea 7
hypothermia 6
spasm 6
splenomegaly 6
hepatosplenomegaly 6
hyperoxia 6
colic 5
chest pain 5
overweight 5
arthralgia 5
eds 5
epigastric pain 5
halitosis 4
skin damage 4
Wind 4
stridor 4
bone pain 4
cancer pain 4
back pain 4
bloating 4
constipation 4
heartburn 3
shortness of breath 3
chills 3
hemoptysis 3
nausea and vomiting 3
paresis 3
Darier's sign 3
bitter taste 3
polyuria 3
Nasal symptoms 3
twitching 3
sleepiness 3
dry eye 3
low back pain 3
hepatomegaly 3
nasal discharge 3
more...
Drug
lysine 1409
Gel 442
Asn 357
Dermatol 327
Pronase 256
NADH 137
ABC 125
Aprotinin 116
CaCl2 112
CaCl2 112
CaCl2 112
lactose 86
ascorbate 81
DNase I 76
CSF 73
IL-2 69
Histamine 67
IFN-gamma 66
DFP 65
Leaf 65
Albumin 62
Papain 59
FAD 57
Asthma 54
L-tyrosine 54
Fragment 52
Fraction 48
NAG 45
MAP 44
pyridoxal phosphate 41
AMC 39
uPA 35
ROS 34
balanced salt solution 34
Biopolymers 32
Gelatin 32
Secretin 29
caffeine 26
Alanine 25
PTH 25
ampicillin 23
Acacia 23
Cardiovasc 22
Nephron 22
CAM 21
Indomethacin 21
Ethanol 20
MRC 20
citric acid 20
Glucagon 20
Ringer's solution 18
Capsicum 18
Cibacron Blue 17
vitamin E 17
CTX 17
Fluorescein 17
Glutathione 16
Paraffin 16
Allergen 15
PTC 15
Bifidobacterium 15
Bromelain 15
Mutagen 15
Hypaque 14
TAT 14
Atropine 14
Fluorescein 14
Angiotensin II 13
Monit 13
Hypaque 13
TiO2 12
CCL 12
Hyaluronidase 11
Hyaluronidase 11
NH3 11
Gabexate mesilate 10
ZnCl2 10
PCP 10
Spectrum 10
Nephron 10
more...
Enzyme
trypsin 42187
chymotrypsin 5478
tryptase 2412
thrombin 1519
pepsin 1491
elastase 1418
collagenase 1166
plasmin 1106
papain 1088
lipase 1016
neuraminidase 908
kallikrein 794
ATPase 734
subtilisin 720
proteinase K 547
chymase 529
proteasome 503
lysozyme 477
RNase 473
thermolysin 463
peroxidase 460
protein kinase 446
RNase 424
neutrophil elastase 374
DNase 370
thromboplastin 366
alkaline phosphatase 364
hyaluronidase 362
urokinase-type plasminogen activator 337
renin 297
phospholipase A2 296
alpha-amylase 281
phospholipase C 277
hyaluronidase 274
cathepsin G 272
tissue kallikrein 226
protein kinase C 226
ribonuclease 220
ribonuclease 219
catalase 214
CD10 209
carboxypeptidase B 206
carboxypeptidase A 197
cathepsin B 194
ERK 186
superoxide dismutase 185
tissue plasminogen activator 184
enterokinase 175
mitogen-activated protein kinase 163
bromelain 157
adenylate cyclase 156
acetylcholinesterase 137
acrosin 136
cathepsin D 136
ACE 136
phosphodiesterase 132
beta-galactosidase 131
glutathione S-transferase 130
endoproteinase Glu-C 124
chondroitinase 122
lactate dehydrogenase 122
chondroitinase 121
APC 118
deaminase 115
alpha-glucosidase 114
leucine aminopeptidase 113
acid phosphatase 113
AMPK 111
deoxyribonuclease 104
deoxyribonuclease 104
ficin 100
PNGase F 99
lysyl endopeptidase 96
reverse transcriptase 95
transglutaminase 94
RNA polymerase 93
ATP synthase 92
calcineurin 92
carboxypeptidase Y 88
invertase 85
more...
Compound
serine 3049
Dec 2973
sodium 2822
arginine 2808
lysine 2534
sulfate 2154
SDS 2149
calcium 2028
DNA 2012
Trypsin 1776
water 1368
Clin 1363
cysteine 1222
ATP 1146
alanine 1071
leucine 1032
Phe 980
phosphate 956
tyrosine 934
methionine 919
EDTA 913
EDTA 913
His 882
Gly 846
Asp 840
ammonium 787
glucose 781
salt 766
NH2 764
urea 749
DEAE 720
bromide 719
galactose 680
threonine 670
TOF 597
hydrogen 556
Ile 539
acetate 528
oxygen 494
Triton X-100 494
Mg2+ 428
tryptophan 397
zinc 387
tryptophan 385
ADP 383
tryptophan 375
tryptophan 375
ADP 369
ADP 369
ethanol 356
HCl 338
proline 330
AMP 325
GTP 314
iron 313
cAMP 311
nitrogen 306
PEG 295
guanidine 272
methanol 265
acrylamide 251
potassium 240
copper 230
acetic acid 226
acetone 216
glutamic acid 207
PEG 198
Tris 195
asparagine 194
TCA 194
aspartic acid 194
GlcNAc 192
manganese 191
aspartic acid 191
silver 190
aspartic acid 189
aspartic acid 188
Serine 181
glutamine 177
glycerol 174
more...