Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.4 (trypsin)
 42,187 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Phytases can catalyze the hydrolysis of indigestible phytate and releases the usable phosphorus. Protease resistance and high activity of enzymes facilitate their biotechnological and medical application. Here we described a genetic manipulation method to improve enzyme tolerance to pepsin, trypsin, and low pH by optimizing the residual side chain of trypsin- and pepsin-sensitive HAP phytase YeAPPA from Yersinia enterocolitica.
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PMID:Engineering Protease-Resistant and Highly Active Phytases. 3177 79


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