Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.21.37 (neutrophil elastase)
4,078 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein neutrophil elastase 2998 HNE 828 cathepsin G 480 Sep 315 myeloperoxidase 293 Mol 269 elastin 249 chymotrypsin 233 serine protease 221 thrombin 211 alpha 1-antitrypsin 188 proteinase 3 184 protease inhibitor 164 IL-8 149 cytokine 148 Pseudomonas 138 collagen 119 granulocyte 113 lipopolysaccharide 99 elastase inhibitor 83 secretory leukocyte protease inhibitor 82 SDS 82 serine protease inhibitor 81 tumor necrosis factor 79 elafin 74 fibronectin 73 albumin 71 matrix metalloproteinase 70 glycoprotein 69 C-reactive protein 68 trypsin inhibitor 66 IL-6 65 TNF 64 MMP-9 60 fibrinogen 59 serine proteinase inhibitor 59 mucin 54 lactoferrin 50 Met 50 kallikrein 50 antithrombin III 48 urokinase-type plasminogen activator 47 interleukin-6 46 plasminogen 46 chemokine 46 collagenase 45 anti-elastase 43 alpha-1-antitrypsin 40 AAT 39 Alpha-1 antitrypsin 38 chymase 38 lysozyme 37 bradykinin 37 TNF-alpha 36 NMR 36 endoplasmic reticulum 36 metalloproteinase 35 LPS 34 histone 34 granulocyte colony-stimulating factor 33 antithrombin 32 peptidase 32 alpha-1 antitrypsin 32 factor Xa 31 antichymotrypsin 31 cathepsin B 31 proteoglycan 31 CD68 30 eosinophil cationic protein 30 MMP-2 30 insulin 29 CD11b 29 serum albumin 28 IL-10 27 mast cell 27 tissue plasminogen activator 27 IL-1 beta 27 polypeptide 27 cathepsin 27 CD4 27 more...

Disease emphysema 341 cystic fibrosis 234 chronic obstructive pulmonary disease 169 cancer 108 lung disease 107 tumor 96 sepsis 93 SDS 87 neutropenia 83 sepsis 82 severe congenital neutropenia 71 asthma 71 adult respiratory distress syndrome 61 pneumonia 60 rheumatoid arthritis 59 ischemia 53 leukemia 53 AAT deficiency 49 liver disease 42 bronchiectasis 40 periodontitis 39 SEM 36 chronic bronchitis 35 acute myeloid leukemia 35 vasculitis 34 bacterial infection 32 atherosclerosis 31 diabetes 30 psoriasis 29 Wegener's granulomatosis 27 genetic disorder 27 disseminated intravascular coagulation 26 lung cancer 26 infectious diseases 25 pulmonary edema 24 COPD 24 arthritis 24 acute promyelocytic leukemia 22 cirrhosis 22 breast cancer 22 respiratory failure 21 ulcerative colitis 20 pancreatitis 20 influenza 19 tumor growth 19 plaque 19 acute pancreatitis 19 myelodysplastic syndrome 18 carcinoma 17 mole 17 mole 17 hepatocellular carcinoma 17 HIV 17 tumor progression 16 adenocarcinoma 16 peritonitis 16 immunodeficiency 15 periodontal disease 15 virus infection 15 inflammatory bowel disease 15 leukopenia 15 stroke 14 abdominal aortic aneurysm 14 colitis 14 glomerulonephritis 14 hypertension 14 myocardial ischemia 13 malnutrition 13 tuberculosis 13 bronchiolitis 13 cold 13 obesity 13 pulmonary fibrosis 13 systemic lupus erythematosus 12 bronchitis 12 Crohn's disease 12 chronic myeloid leukemia 12 Infection 12 bronchitis 12 respiratory disease 12 more...

Symptom respiratory distress 57 anesthesia 23 pain 14 dyspnea 9 diarrhea 9 cough 9 hyperoxia 8 erythema 6 collapse 5 splenomegaly 3 fatigue 3 hypothermia 3 headache 3 functional recovery 3 BHS 2 disturbed balance 2 starvation 2 ataxic gait 2 constipation 2 Air trapping 2 angina 2 colic 1 twitching 1 nausea 1 nausea and vomiting 1 Welt 1 exertional dyspnea 1 abdominal discomfort 1 HSA 1 metamorphopsia 1 exhaustion 1 abdominal pain 1 Skin symptoms 1 productive cough 1 anorexia 1 dystonia 1 pallor 1 stridor 1 inflammation of the tonsils 1 flushing 1 weakness 1 bradypnea 1 microbial colonization 1 overweight 1 cachexia 1 seizures 1 flank pain 1 analgesia 1 syncope 1 stigma 1 chills 1 Gastrointestinal symptoms 1 thinning 1 Neuropathic pain 1 myalgia 1 chest pain 1

Drug lysine 49 Dermatol 45 Sivelestat 37 CSF 30 Cardiovasc 25 ICI 25 G-CSF 19 Asn 18 Sivelestat sodium hydrate 17 Gel 15 DNase I 13 Ulinastatin 11 IL-2 11 Aprotinin 10 IFN-gamma 9 ROS 8 DFP 7 Asthma 7 ENT 7 EPI 7 Nephron 6 Gelatin 6 Nephron 6 vitamin E 6 uPA 6 ACT 5 Prolastin 5 CaCl2 4 MAP 4 CaCl2 4 Dial 4 Albumin 4 Antithrombin III 4 CaCl2 4 ascorbate 4 ABC 4 Glutathione 3 Urokinase 3 Areca 3 Prednisolone 3 Doxycycline 3 citric acid 3 TAT 3 Biopolymers 3 MDS 3 Rebamipide 3 Alanine 2 nitroglycerin 2 Cilomilast 2 ROC 2 Allergen 2 ATV 2 Indomethacin 2 Fluorescein 2 Hyaluronidase 2 balanced salt solution 2 Iloprost 2 Hyperforin 2 CAM 2 NBT 2 Cimetidine 2 Histamine 2 Hyaluronidase 2 CCL 2 Cimetidine 2 Ringer's solution 2 Monit 2 AMC 2 Herceptin 2 Fluorescein 2 ISP 2 EPA 1 niacin 1 Piclamilast 1 Ceftazidime 1 Ocrelizumab 1 Bayer 1 Budesonide 1 CTA 1 Serum albumin 1 more...

Enzyme neutrophil elastase 4078 elastase 1231 cathepsin G 470 trypsin 374 peroxidase 310 chymotrypsin 286 thrombin 206 plasmin 165 collagenase 90 kallikrein 86 mitogen-activated protein kinase 54 proteinase-3 53 urokinase-type plasminogen activator 52 tryptase 47 thromboplastin 45 aspartate aminotransferase 39 NADPH oxidase 37 NADPH oxidase 37 lysozyme 37 tissue plasminogen activator 36 MMP-3 33 cathepsin B 32 chymase 32 ERK 31 papain 30 matrix metalloproteinase 9 29 catalase 28 subtilisin 28 APC 26 protein kinase C 26 macrophage elastase 23 superoxide dismutase 23 DNase 23 pseudolysin 19 cathepsin L 19 lactate dehydrogenase 19 caspase-3 17 alanine aminotransferase 16 beta-glucuronidase 16 tissue kallikrein 15 proteinase K 14 proteasome 13 cathepsin D 13 CD10 13 peptidylarginine deiminase 13 phosphodiesterase 12 matrix metalloproteinase 2 12 pepsin 12 protein kinase 12 reverse transcriptase 11 caspase-1 11 xanthine oxidase 11 granzyme B 11 neutrophil collagenase 11 MIP 10 cathepsin C 10 thermolysin 10 MMP 10 phospholipase A2 9 lipase 9 endonuclease 9 transglutaminase 9 alkaline phosphatase 9 phospholipase C 8 interstitial collagenase 8 cathepsin K 8 DNase II 8 hyaluronidase 8 creatine kinase 7 ACS 7 luciferase 7 Hageman factor 6 RNA polymerase 6 deoxyribonuclease 6 RNase 6 chloramphenicol acetyltransferase 6 hyaluronidase 6 deoxyribonuclease 6 focal adhesion kinase 6 BAL 5 more...

Compound serine 521 Dec 306 DNA 255 Clin 244 oxygen 189 alanine 172 Phe 121 sodium 117 methionine 107 acetate 103 leucine 100 sulfate 96 arginine 95 calcium 89 SDS 88 lysine 81 water 66 TNF 64 cysteine 57 valine 57 His 46 hydrogen 42 salt 41 tyrosine 40 NH2 39 Pac 35 Gly 35 nitrogen 33 Ile 32 phosphate 32 Serine 32 H2O2 32 AAT 32 nitric oxide 28 Asp 27 EDTA 26 EDTA 26 Heparin 26 ICI 25 glucose 24 threonine 23 proline 23 urea 22 PMA 22 retinoic acid 20 PMA 20 Thrombin 19 Elastin 19 hyaluronic acid 17 PEG 16 tryptophan 16 tryptophan 16 ammonium 16 tryptophan 16 tryptophan 16 creatinine 15 Trypsin 15 prostacyclin 15 chromate 14 ATP 14 TOF 14 zinc 13 ADP 13 glutamic acid 12 Plasmin 12 HCl 12 THP 12 FMLP 12 THP 12 PEG 11 acetic acid 11 ethanol 11 ACS 11 copper 10 PMSF 10 CO2 10 cAMP 9 guanidine 9 ADP 9 prostaglandin E1 9 more...

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